Na Wu Tingyao

Inā ʻaʻole hiki ke hoʻopaʻa ʻia ka momona, aia kekahi ala e hoʻolōʻihi ai i ka piʻi ʻana o ke kaumaha me ka ʻole o ka hoʻopau ʻana i ka ʻai, a i ʻole e loaʻa ke kaumaha ma ke olakino?Ua hōʻike ʻia kahi hōʻike noiʻi i paʻi ʻia e kahi hui South Korea ma NutrientsʻO Ganoderma lucidumHiki iā ia ke hoʻoikaika i ka AMPK, he enzyme nui i ka metabolism ikehu cell, e hōʻemi i ka hōʻiliʻili momona, hoʻomaikaʻi i ka hoʻohana ʻana i ka glucose a hoʻemi i ka pilikia o ka momona, ka momona momona, hyperglycemia a me hyperlipidemia i hoʻoulu ʻia e ka meaʻai momona momona (HFD).

Ua paʻi pū nā mea noiʻi mai Chungbuk National University, Kyungpook National University a me National Institute of Horticultural and Herbal Science o South Korea i kā lākou ʻike i ka pukana "Nutrients" o Nowemapa 2020 (Nutrients Journal):

No nā ʻiole e ʻai i ka momona momona, ināʻO Ganoderma lucidumHoʻohui ʻia ka pauka extract (GEP) i kā lākou meaʻai, ma hope o 12 mau pule o ka hoʻokolohua, ʻaʻohe pilikia o nā ʻiole me ke kaumaha, ka momona o ke kino, ke kū ʻana o ka insulin, ke kō koko a i ʻole nā ​​lipid koko.Eia kekahi, ʻoi aku ka nuiʻO Ganoderma lucidumHoʻohui ʻia ka ʻiole, ʻoi aku ka pili o kēia mau ʻiole e ʻai i ka momona momona i nā ʻiole me ka meaʻai chow maʻamau (ND) a me ka meaʻai kaulike, hiki ke ʻike ʻia ma ka helehelena.

E ʻai i ka nui like o ka hānai akā e emi iho ka momona

Hiki ke ʻike ʻia ma ka Figure 1 ma hope o ka hoʻokolohua ʻumikūmālua pule, ʻo ka nui a me ke kaumaha o nā ʻiole ma kahi momona momona ua aneane pālua ka nui o nā ʻiole ma ka ʻai chow maʻamau, akā ʻo nā ʻiole i hānai pū ʻia meʻO Ganoderma lucidumLoaʻa nā loli like ʻole o ka extract ─ ʻO ka hoʻohui ʻana o 1%ʻO Ganoderma lucidumʻAʻole maopopo ka extract, akā ʻoi aku ka nui o ka hoʻohui ʻana o 3%, ʻoi aku ka nui o ka hopena inhibitory o ka hoʻohui ʻana i ka 5% i ka portly.

ʻO kaʻO Ganoderma lucidumka mea i ʻai ʻia e kēia mau ʻiole ma o ka unuhi ʻana i nā kino hua maloʻo o nā mea kikoʻī i kanu ʻiaʻO Ganoderma lucidumnā kānana (ASI7071) me 95% ethanol (waiʻona) e ka Mushroom Research Department o ka National Institute of Horticultural and Herbal Science o South Korea.ʻO nā mea bioactive nui o kaʻO Ganoderma lucidum'Ōleloʻia ka extract ma ka Papa 1: He 53% nā waikawa Ganoderic, a he 27% ka polysaccharides.Hōʻike ʻia nā haku meaʻai i hoʻohana ʻia ma kēia haʻawina ma ka Papa 2.

Ma muli o ka ʻawaʻawa o ka waikawa Ganoderic, ʻaʻole hiki i kekahi ke noʻonoʻo inā pili ia i ka ʻai ʻana o nā ʻiole a lilo ke kaumaha.ʻAʻole!Hōʻike nā hopena i ka ʻai ʻana o nā ʻiole ʻelua i ka nui o ka meaʻai i kēlā me kēia lā (Figure 2 ʻākau), akā aia nā ʻokoʻa nui i ka loaʻa ʻana o ke kaumaha o nā ʻiole ma mua a ma hope o ka hoʻokolohua (Figure 2 hema).Me he mea lā ke kumu o kēiaʻO Ganoderma lucidumhiki i ka extract ke hoʻokūkū me ka meaʻai momona kiʻekiʻe e pili ana i ka hoʻonui ʻana i ka hana metabolic.

ʻO Ganoderma lucidumKāohi i ka hōʻiliʻili momona a me ka hypertrophy adipocyte

ʻO ka loaʻa ʻana o ke kaumaha e pili pinepine i ka "ulu o ka ʻiʻo a i ʻole ka momona".Hiki ke ulu i nā ʻiʻo.Aia ka pilikia i ka ulu ʻana o ka momona, ʻo ia hoʻi, ke keʻokeʻo adipose tissue (WAT), ʻo ia ke kuleana no ka mālama ʻana i nā calorie keu i ke kino, ua hoʻonui.Hiki ke hōʻiliʻili kēia mau momona i nā ʻāpana like ʻole.Hoʻohālikelike ʻia me ka momona subcutaneous, ʻo ka momona visceral (i kapa ʻia ʻo ka momona ʻōpū) i hōʻiliʻili ʻia ma waena o nā ʻāpana like ʻole i loko o ka ʻōpū o ka ʻōpū a me ka momona ectopic i ʻike ʻia i loko o nā ʻiʻo nonadipose (e like me ka ate, ka puʻuwai a me ka ʻiʻo) pili pinepine i nā pilikia pili i ka momona e like me ka maʻi diabetes. , ʻaʻa momona a me ka maʻi cardiovascular.

Ma muli o nā hopena o nā hoʻokolohua holoholona ma luna.ʻO Ganoderma lucidumʻAʻole hiki i ka extract ke hōʻemi wale i ka hōʻiliʻili o ka momona subcutaneous, ka momona epididymal (e hōʻike ana i ka momona visceral) a me ka momona mesenteric (e hōʻike ana i ka momona o ka ʻōpū) (Figure 3) akā e hoʻemi pū i ka momona ma ke ake (Figure 4);ʻOi aku ka maʻalahi o ka ʻike ʻana mai ka ʻāpana o nā kiko adipose o ka epididymis e loli ka nui o nā adipocytes ma muli o ke komo ʻana oʻO Ganoderma lucidumunuhi (Figure 5).

ʻO Ganoderma lucidumhoʻemi i ka hyperlipidemia, hyperglycemia a me ka insulin resistance

ʻAʻole ʻo Adipose tissue wale nō kahi hale kūʻai no ke kino e hōʻiliʻili i ka momona nui akā hūnā pū kekahi i nā "hormones momona" e pili ana i ka carbohydrate a me ka lipid metabolism.Ke piʻi aʻe ka momona o ke kino, ʻo ka pilina o kēia mau momona momona e hoʻemi i ka naʻau o nā cell tissue i ka insulin (ʻo ia ka mea i kapa ʻia ʻo "insulin resistance"), ʻoi aku ka paʻakikī o nā cell e hoʻohana i ka glucose.

ʻAʻole e hoʻonui wale ka hopena i ke kō koko akā e hoʻoulu ai i ka metabolism lipid abnormal, e hoʻoulu ai i nā pilikia e like me ka hyperlipidemia, ka momona momona a me ke atherosclerosis.I ka manawa like, e koi ʻia ka pancreas e huna hou i ka insulin.Ma muli o ka hopena o ka insulin ponoʻī i ka hoʻoulu ʻana i ka momona a me ka mumū, ʻaʻole i hoʻopau wale ka insulin huna i ka pilikia akā ʻoi aku ka nui o ka momona a me nā pilikia āpau i luna.

ʻO ka mea pōmaikaʻi, e like me kēia hōʻike noiʻi South Korea,ʻO Ganoderma lucidumHe hopena hoʻoponopono ka extract i ka huna ʻole ʻana o nā hormones momona (leptin a me adiponectin), hoʻonui i ka pale ʻana o ka insulin a me ka hoʻemi ʻana i ka hoʻohana ʻana i ka glucose ma muli o ka ʻai momona.Hōʻike ʻia ka hopena kikoʻī ma nā hoʻokolohua holoholona i ʻōlelo ʻia ma luna nei: No nā ʻiole ma kahi momona momona i hoʻohui ʻia meʻO Ganoderma lucidumʻO kā lākou dyslipidemia a me ka piʻi ʻana o ke kō koko a me ka insulin i maʻalahi (Pau 3 a me 6).

ʻO Ganoderma lucidumho'āla i ka enzyme kī o ka ikehu cell metabolism - AMPK

No ke aha e hiki aiʻO Ganoderma lucidumextract e hoʻohuli i ka pilikia o ka meaʻai momona momona i kahi huli?Lawe nā mea noiʻi i ka ʻiʻo adipose a me ka ʻiʻo ate o nā ʻiole hoʻokolohua i ʻōlelo ʻia ma luna no ka nānā ʻana e ʻike i ka ʻokoʻa o kēia mau cell ma muli o ka hoʻohuiʻO Ganoderma lucidumextract ma lalo o ka like kiʻekiʻe-momonaʻai.

Ua ʻike ʻia kaʻO Ganoderma lucidumHoʻoikaika ka extract i ka hana o ka enzyme AMPK (5′ adenosine monophosphate activated protein kinase), nona ke kuleana no ka hoʻoponopono ʻana i ka ikehu i loko o nā adipocytes a me nā pūnaʻi ate.Hiki i ka AMPK i ho'ā 'ia ke ke'ake'a i ka hō'ike 'ana o nā genes e pili ana i ka adipogenesis a ho'onui i ka insulin receptor a me ka glucose transporter (protein e lawe ana i ka glucose mai waho o ke keena a i loko o ke keena) ma ka ili pūnaewele.

ʻO ia hoʻi,ʻO Ganoderma lucidumhakakā ka extract i ka meaʻai momona nui ma o ka mīkini i ʻōlelo ʻia ma luna, ma laila e hōʻemi ai i ka hōʻiliʻili momona, hoʻonui i ka hoʻohana ʻana i ka glucose, a i ka hopena e hoʻokō i ka pahuhopu e hōʻemi i ke kaumaha.

ʻOiaʻiʻo, he mea nui iaʻO Ganoderma lucidumHiki i ka extract ke hoʻoponopono i ka hana AMPK no ka mea pili ka hana AMPK i hoʻemi ʻia me ka momona a i ʻole ka maʻi diabetes type 2 i hoʻoulu ʻia e ka meaʻai momona.ʻO ka metformin lāʻau lapaʻau hypoglycemic maʻamau i hoʻohana ʻia i ka hoʻomaʻamaʻa lapaʻau e pili ana i ka hoʻonui ʻana i ka hana AMPK o nā adipocytes a me nā pūnaʻi ate.I kēia manawa, manaʻo ʻia ka hoʻonui ʻana i ka hana AMPK ma ke ʻano he hoʻolālā kūpono e hoʻonui ai i ka pae metabolic i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou e hoʻomaikaʻi ai i ka momona.

No laila ka noiʻi maʻO Ganoderma lucidummālama maoli i ka holomua o ka ʻepekema a me ka wikiwiki o ka manawa, a ʻo ka noiʻi maʻalahi i ʻōlelo ʻia mai South Korea e hāʻawi i ka hopena maʻalahi no ʻoe a me aʻu e "makemake e ʻai maikaʻi akā ʻaʻole makemake e hoʻopilikia ʻia e ka ʻai maikaʻi. ”, ʻo ia hoʻi, e hoʻopihaʻO Ganoderma lucidumextract i loaʻa nā ʻano like ʻole ganoderic acid aʻO Ganoderma lucidumpolysaccharides.

[Kumu ʻikepili] Hyeon A Lee, et al.Hoʻemi ʻo Ganoderma lucidum Extract i ka Insulin Resistance ma ka hoʻonui ʻana i ka hoʻoulu ʻana o AMPK i nā ʻiole momona momona momona.Nā meaʻai.2020 ʻOkakopa 30;12(11):3338.

HOPE

No ka mea kākau/ Ms. Wu Tingyao

Ua hōʻike ʻo Wu Tingyao ma ka lima muaʻO Ganoderma lucidumʻike

mai ka makahiki 1999. ʻO ia ke kumu oHoola me Ganoderma(i paʻi ʻia ma The People's Medical Publishing House ma ʻApelila 2017).

★ Ua paʻi ʻia kēia ʻatikala ma lalo o ka mana kūʻokoʻa o ka mea kākau ★ ʻAʻole hiki ke hana hou ʻia nā hana ma luna aʻe, ʻoki ʻia a hoʻohana ʻia ma nā ʻano ʻē aʻe me ka ʻole o ka ʻae ʻana o ka mea kākau ★ ʻAʻole i ʻae ʻia ka ʻōlelo ma luna, e hahai ka mea kākau i kāna mau kuleana pili i ke kānāwai ★ ʻO ke kumu kumu. Ua kākau ʻia nā kikokikona o kēia ʻatikala ma ka ʻōlelo Pākē e Wu Tingyao a unuhi ʻia i ka ʻōlelo Pelekania e Alfred Liu.Inā loaʻa kekahi ʻokoʻa ma waena o ka unuhi (English) a me ka unuhi mua (Pake), e lanakila ka Pākē mua.Inā he nīnau ka poʻe heluhelu, e ʻoluʻolu e kelepona i ka mea kākau kumu, ʻo Ms. Wu Tingyao.