Wu Tingyao

Idan ba za a iya danne kiba ba, shin akwai wata hanyar da za a rage kiba ba tare da hana ci ba, ko ma a kara nauyi cikin koshin lafiya?Wani rahoton bincike da wata tawagar Koriya ta Kudu a cikin abinci mai gina jiki ta buga ya nuna hakanGanoderma lucidumna iya kunna AMPK, maɓalli mai mahimmanci a cikin metabolism na makamashin sel, don rage yawan kitse, inganta amfani da glucose da rage haɗarin kiba, hanta mai kitse, hyperglycemia da hyperlipidemia haifar da abinci mai mai yawa (HFD).

Masu bincike daga Jami'ar Kasa ta Chungbuk, Jami'ar Kasa ta Kyungpook da Cibiyar Horticultural and Herbal Science na Koriya ta Kudu sun buga bincikensu tare a cikin fitowar Nuwamba 2020 na "Ma'adanai" (Jarida mai gina jiki):

Ga berayen da suke cin abinci mai kitse, idanGanoderma luciduman ƙara cire foda (GEP) zuwa abincin su, bayan makonni 12 na gwaji, berayen ba su da wata matsala mai mahimmanci tare da nauyi, kitsen jiki, juriya na insulin, sukarin jini ko jini.Bugu da ƙari, ƙariGanoderma luciduman ƙara cirewa, mafi kusancin waɗannan alamomin mice waɗanda ke cin abinci mai kitse za su kasance ga na ɓeraye masu cin abinci na yau da kullun (ND) da daidaiton abinci mai gina jiki, wanda har ma ana iya gani daga bayyanar.

Ku ci abinci iri ɗaya amma ku rage mai

Za a iya gani daga Hoto na 1 cewa bayan gwaji na makonni goma sha biyu, girman da nauyin berayen akan abinci mai yawan kitse sun kusan ninki biyu na mice akan cin abinci na yau da kullun, amma berayen da suma aka ciyar dasu.Ganoderma lucidumcirewa ya sami canje-canje daban-daban ─ Ƙarin 1%Ganoderma lucidumtsantsa har yanzu ba a bayyane yake ba, amma ƙari na 3% a bayyane yake, musamman ma tasirin hanawa na ƙara 5% zuwa portly ya fi mahimmanci.

TheGanoderma lucidumcire cewa waɗannan berayen sun samo su ne ta hanyar fitar da busassun gawarwakin da aka noma na wucin gadiGanoderma lucidumdamuwa (ASI7071) tare da 95% ethanol (giya) ta Sashen Bincike na Naman kaza na Cibiyar Nazarin Horticultural da Herbal Science na Koriya ta Kudu.Manyan abubuwan da ke haifar da bioactive naGanoderma lucidumAn bayyana tsantsa a cikin Tebur 1: Ganoderic acid yana lissafin 53%, kuma polysaccharides suna lissafin 27%.Abubuwan abinci da aka yi amfani da su a cikin wannan binciken an bayyana su a cikin Table 2.

Kamar yadda Ganoderic acid yana da ɗanɗano mai ɗaci, wanda ba zai iya taimakawa ba sai dai yana mamakin ko yana rinjayar abincin da ke cikin mice kuma yana haifar da asarar nauyi.A'a!Sakamakon ya nuna cewa duka ƙungiyoyin berayen sun ci kusan adadin abinci iri ɗaya a kowace rana (Hoto na 2 dama), amma akwai bambance-bambance masu yawa a cikin nauyin mice kafin da bayan gwajin (Hoto 2 hagu).Wannan yana nufin cewa dalilin da ya saGanoderma lucidumtsantsa iya gasa tare da wani high-mai rage cin abinci na iya zama alaka da kayan haɓɓaka aiki na rayuwa yadda ya dace.

Ganoderma lucidumyana hana tarin kitse da hypertrophy adipocyte

Yawan nauyi yana da alaƙa da "ci gaban tsoka ko mai".Babu laifi girma tsokoki.Matsalar ta ta'allaka ne a cikin girma mai, wato, farin adipose tissue (WAT), wanda ke da alhakin adana yawan adadin kuzari a cikin jiki, ya karu.Wadannan karin kitse na iya taruwa a sassa daban-daban.Idan aka kwatanta da kitsen da ke cikin jiki, kitse na visceral (wanda kuma ake kira kitsen ciki) da ya taru tsakanin gabobin jiki daban-daban a cikin kogon ciki da kitsen ectopic da ke bayyana a cikin kyallen jikin da ba na dipose (kamar hanta, zuciya da tsoka) galibi suna da alaƙa da haɗari masu alaƙa da kiba kamar ciwon sukari. , hanta mai kitse da cututtukan zuciya.

Dangane da sakamakon gwaje-gwajen dabba da ke sama,Ganoderma lucidumtsantsa ba zai iya rage tarin kitsen da ke cikin jiki ba, kitsen epididymal (mai wakiltar kitsen visceral) da kitsen mesenteric (mai wakiltar kitse na ciki) (Hoto 3) amma kuma yana rage kitse a cikin hanta (Hoto 4);Yana da mahimmanci don ganin daga sashin adipose tissues na epididymis cewa girman adipocytes zai canza saboda tsoma baki.Ganoderma lucidumcire (Hoto na 5).

Ganoderma lucidumyana rage hyperlipidemia, hyperglycemia da juriya na insulin

Adipose nama ba kawai wurin ajiya ba ne don jiki don tara kitse mai yawa amma kuma yana ɓoye “hormones masu kitse” daban-daban waɗanda ke shafar carbohydrate da metabolism na lipid.Lokacin da abun ciki mai kitse na jiki ya fi girma, hulɗar waɗannan hormones mai kitse zai rage jin daɗin ƙwayoyin nama zuwa insulin (wannan shine abin da ake kira "juriya na insulin"), yana sa ya fi wahala ga sel suyi amfani da glucose.

Sakamakon ba zai ƙara yawan sukarin jini kawai ba amma har ma yana haifar da rashin lafiyar lipid metabolism, haifar da matsaloli irin su hyperlipidemia, hanta mai kitse da atherosclerosis.A lokaci guda kuma, ƙwayar ƙwayar cuta za a tilasta ta ta ɓoye ƙarin insulin.Domin ita kanta Insulin tana da tasirin inganta tarin kitse da kumburi, insulin da aka boye fiye da kima ba wai kawai ya magance matsalar ba har ma yana sa kiba da duk matsalolin da ke sama su yi muni.

Abin farin ciki, a cewar wannan rahoton binciken Koriya ta Kudu,Ganoderma lucidumtsantsa yana da sakamako mai gyara akan ɓoyayyen ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta (leptin da adiponectin), haɓaka juriya na insulin da rage yawan amfani da glucose ta hanyar abinci mai kitse.Ana nuna takamaiman tasiri a cikin gwaje-gwajen dabba da aka ambata a sama: Ga berayen akan abinci mai kitse da aka ƙara da su.Ganoderma lucidumcirewa, dyslipidemia da haɓakar sukarin jini da insulin sun kasance masu sauƙi (Table 3 da Figure 6).

Ganoderma lucidumyana kunna maɓallin enzyme na metabolism na makamashin sel - AMPK

Me yasa zai iyaGanoderma lucidumtsantsa ya juya rikicin cin abinci mai yawan kitse ya zama juyi?Masu binciken sun fitar da nama da nama na hanta na berayen gwaji da aka ambata a sama don bincike don ganin yadda waɗannan ƙwayoyin za su bambanta saboda kari.Ganoderma lucidumcire a karkashin wannan high-fat rage cin abinci.

An gano cewaGanoderma lucidumcirewa ya inganta aikin enzyme AMPK (5' adenosine monophosphate activated protein kinase), wanda ke da alhakin daidaita makamashi a cikin adipocytes da ƙwayoyin hanta.AMPK da aka kunna zai iya hana bayyanar kwayoyin halittar da ke da alaƙa da adipogenesis kuma yana ƙara mai karɓar insulin da mai jigilar glucose (protein da ke jigilar glucose daga wajen tantanin halitta zuwa cikin tantanin halitta) akan saman tantanin halitta.

Watau,Ganoderma lucidumtsantsa yana yaki da abinci mai kitse ta hanyar tsarin da aka ambata a sama, ta yadda zai rage yawan kitse, inganta amfani da glucose, da kuma cimma burin rage kiba.

A gaskiya ma, yana da matukar ma'ana cewaGanoderma lucidumcirewa na iya daidaita ayyukan AMPK saboda rage yawan ayyukan AMPK yana da alaƙa da kiba ko nau'in ciwon sukari na 2 wanda abinci mai kitse ya jawo.Maganin da ake amfani da shi na hypoglycemic metformin a cikin aikin asibiti yana da alaƙa da haɓaka ayyukan AMPK na adipocytes da ƙwayoyin hanta.A halin yanzu, ana ɗaukar haɓaka ayyukan AMPK a matsayin dabara mai yuwuwa don haɓaka ƙimar rayuwa a cikin haɓaka sabbin magunguna da yawa don haɓaka kiba.

Don haka bincike akanGanoderma lucidumda gaske yana ci gaba da ci gaban kimiyya da saurin zamani, kuma bincike mai zurfi da aka ambata a sama daga Koriya ta Kudu ya ba da mafita mafi sauƙi a gare ni da ku waɗanda “suna son cin abinci mai kyau amma ba sa son cin abinci mai kyau ya shafe su. ”, wato don sake cikawaGanoderma lucidumcirewa wanda ya ƙunshi nau'ikan ganoderic acid daGanoderma lucidumpolysaccharides.

[Tsarin Bayanai] Hyeon A Lee, et al.Ganoderma lucidum Cire Yana Rage Juriya na Insulin ta Haɓaka Kunnawar AMPK a cikin Ƙaƙƙarfan Abincin Abinci mai Kiba mai Kiba.Abubuwan gina jiki.Oktoba 30, 12 (11): 3338.

KARSHE

Game da marubucin / Ms. Wu Tingyao

Wu Tingyao ya kasance yana bayar da rahoto da farkoGanoderma lucidumbayani

tun 1999. Ita ce marubucinWaraka tare da Ganoderma(an buga a The People's Medical Publishing House a Afrilu 2017).

★ An buga wannan labarin ne a ƙarƙashin izini na musamman na marubuci ★ Wadannan ayyukan da ke sama ba za a iya sake su ba, cirewa ko amfani da su ta wasu hanyoyi ba tare da izini daga marubucin ba. Wu Tingyao ne ya rubuta wannan labarin da Sinanci kuma Alfred Liu ya fassara shi zuwa Turanci.Idan akwai wani sabani tsakanin fassarar (Turanci) da na asali (China), asalin Sinanci zai yi nasara.Idan masu karatu suna da wasu tambayoyi, tuntuɓi marubuciyar asali, Ms. Wu Tingyao.