Grifola frondosa (nke a na-akpọkwa Maitake) bụ obodo ugwu nke ugwu Japan.Ọ bụ ụdị ero nri-ọgwụ na-atọ ụtọ na mmetụta ọgwụ.A na-ele ya anya dị ka ụtụ maka ezinụlọ ndị eze Japan kemgbe oge ochie.Azụlitebeghị ero a nke ọma ruo etiti afọ 1980.Kemgbe ahụ, ndị ọkà mmụta sayensị na Japan emeela nyocha buru ibu na ero Maitake na kemistri, biochemistry na ọgwụ ọgwụ, na-egosi na ero Maitake bụ ero kacha bara uru maka ọgwụ na nri.Karịsịa Maitake D-fraction, ihe kacha arụ ọrụ nke ọma ewepụtara na ero Maitake, nwere mmetụta mgbochi ọrịa kansa siri ike.

Nnyocha zuru oke na mmetụta ọgwụ nke Grifola frondosa na Japan, Canada, Italy na United Kingdom na afọ ndị na-adịbeghị anya egosila na Grifola frondosa nwere mmetụta nke mgbochi ọrịa cancer, nkwalite mgbochi ọrịa, mgbochi ọbara mgbali elu, na-ebelata shuga ọbara, na-ebelata lipids ọbara na mgbochi ịba ọcha n'anya nje.

Na nchịkọta, Grifola frondosa nwere ọrụ nlekọta ahụike ndị a:
1.N'ihi na ọ bara ụba na ígwè, ọla kọpa na vitamin C, ọ nwere ike igbochi anaemia, scurvy, vitiligo, arteriosclerosis na ụbụrụ thrombosis;
2.Ọ nwere nnukwu selenium na chromium ọdịnaya, nke nwere ike ichebe imeju na pancreas, gbochie imeju imeju na ọrịa shuga;ọdịnaya selenium dị elu ya nwekwara ọrụ nke igbochi ọrịa Keshan, ọrịa Kashin-Beck na ọrịa obi ụfọdụ;
3.Ọ nwere ma calcium na vitamin D. Nchikota nke abụọ nwere ike igbochi ma na-emeso rickets n'ụzọ dị irè;
4.Ọdịnaya zinc dị elu bara uru iji kwalite mmepe ụbụrụ, nọgide na-ahụ anya ma kwalite ọgwụgwọ ọnya;
5.Nchikota nke nnukwu ọdịnaya nke vitamin E na selenium na-enyere ya aka inwe mmetụta nke mgbochi ịka nká, nkwalite ncheta na nkwalite uche.N'otu oge ahụ, ọ bụ ezigbo immunomodulator.
6.Dị ka a omenala Chinese ọgwụ, Grifola frondosa bụ Ẹkot Polyporus umbellatus.Ọ nwere ike ịgwọ dysuria, edema, ụkwụ egwuregwu, cirrhosis, ascites na ọrịa shuga.
7.Ọ nwekwara mmetụta nke igbochi ọbara mgbali elu na oke ibu.
8.The elu selenium ọdịnaya nke Grifola frondosa nwere ike igbochi cancer.

Nnwale anụmanụ na nnwale ụlọ ọgwụ na-egosi na Maitake D-fraction na-arụ ọrụ mgbochi ọrịa kansa site na akụkụ ndị a:
1.Ọ nwere ike ịgbalite sel ndị na-alụso ọrịa ọgụ dị ka phagocytes, mkpụrụ ndụ egbu egbu eke na mkpụrụ ndụ cytotoxic T, ma mee ka nzuzo nke cytokines dị ka leukin, interferon-γ, na tumor necrosis factor-α.
2.Ọ nwere ike ịkpalite apoptosis nke mkpụrụ ndụ kansa.
3.Combined na omenala chemotherapy ọgwụ (dị ka mitomycin na Carmustine), ọ bụghị nanị na-amụba irè nke ọgwụ ma na-ebelata nsi mmetụta na mmetụta n'oge chemotherapy.
4.Synergistic mmetụta na immunotherapy ọgwụ (interferon-α2b).
5. Ọ nwere ike belata ihe mgbu nke ndị ọrịa cancer dị elu, na-abawanye agụụ ma melite ogo ndụ nke ndị ọrịa.