Qoraal/Zhi-bin LIN (professor ka ah Waaxda Farmashiistaha, Jaamacadda Peking ee Sayniska Caafimaadka Aasaasiga ah)
★Maqaalkan waxa laga soo xigtay ganodermanews.com.Waxaa lagu daabacay ogolaanshaha qoraaga.

Sidee buu Lingzhi (oo sidoo kale loo yaqaan Ganoderma ama likaha Reishi) u ciyaara saameyntiisa ka hortagga fayraska?Waxaa guud ahaan la aqbalay in Lingzhi uu si aan toos ahayn u diido fayrasyada inay soo galaan jidhka bini'aadamka oo ay ku bataan oo ay dhaawacaan jidhka isaga oo kor u qaadaya habka difaaca jirka.Lingzhi waxa kale oo uu yarayn karaa bararka uu keeno fayrasku iyo dhaawaca xubnaha muhiimka ah sida sambabada, wadnaha, beerka iyo kelyaha iyada oo loo marayo saamaynta anti-oxidative iyo xagjirnimada bilaashka ah.Intaa waxaa dheer, waxaa jiray warbixino cilmi-baaris ah tan iyo 1980-meeyadii in Lingzhi, gaar ahaan triterpenoid-yada ku jira, ay saameyn ku yeeshaan fayrasyada kala duwan.

Professor Zhi-bin LIN wuxuu ku hawlanaa cilmi-baarista Lingzhifarmashiistaha muddo nus qarni ah waana hormuudka cilmi baarista Lingzhi ee Shiinaha.(Sawirka/Wu Tingyao)

Cudurka Coronavirus 2019 (COVID-19) wali wuu sii wareegayaa wuxuuna ku faafay caalamka oo dhan.Ka-hortagga iyo xakameynta faafitaanka cudurka, daweynta bukaannada iyo soo afjaridda cudurka waa rajada iyo mas'uuliyadda guud ee bulshada oo dhan.Warbixinnada kala duwan ee warbaahinta, waan ku faraxsanahay inaan arko kuwa badanGanoderma lucidumsoosaarayaasha ayaa ugu deeqa sahayda kahortaga cudurka iyo agabka Lingzhi aagagga cudurka iyo kooxaha caafimaadka Hubei.Waxaan rajeynayaa in Lingzhi uu gacan ka geysan karo ka hortagga novel coronavirus pneumonia oo uu ilaaliyo dhakhaatiirta iyo bukaannada.

Dambiilaha cudurkaan waa coronavirus novel 2019 (SARS-CoV-2).Kahor intaanay jirin dawooyinka coronavirus-ka-novel-ka-hortagga ah iyo tallaalada, dariiqa ugu muhiimsan uguna waxtarka badan wuxuu ahaa in la karantiilo bukaanka, la sameeyo astaamo iyo daaweyn taageero ah, kor loogu qaado difaaca, ka hortagga fayraska inay waxyeeleeyaan oo waxyeelleeyaan xubnaha iyo unugyada muhiimka ah ee jirka ugu dambeyntiina laga adkaado cudurka.Dadka u nugul, kor u qaadista nidaamka difaaca waxay ka caawisaa inay iska caabiyaan weerarada fayraska.

Intaa waxaa dheer, goobta caafimaadku waxay sidoo kale isku dayeysaa inay hesho dawooyin la dagaallami kara fayraskan cusub daawooyinka fayraska ee jira.Waxaa jira warar xan ah oo badan oo ku saabsan internetka.Haddii ay wax ku ool yihiin iyo in kale weli si caafimaad looma xaqiijin.

Lingzhi wuxuu wanaajiyaa awoodda ka hortagga fayraska ee habka difaaca jirka.

Lingzhi (Ganoderma lucidumiyoGanoderma sinensis) waa qalab dawo ah oo dhaqameed Shiinees ah oo sharci ah oo ku jira Pharmacopoeia ee Jamhuuriyadda Dadka Shiinaha (Qaybta Koowaad), sida laga soo xigtay Lingzhi wuxuu kabi karaa qi, dareemaha dajinta, nafiska qufaca iyo neefta, waxaana loo isticmaali karaa nasasho la'aan, hurdo la'aan, garaaca wadnaha, sambabada oo yaraada iyo qufac iyo hinraag, cudur wax cuna iyo neefta oo yaraata, iyo cunto xumo.Ilaa hadda, in ka badan boqol nooc oo dawooyinka Lingzhi ah ayaa loo oggolaaday in loo suuq geeyo ka hortagga iyo daaweynta cudurrada.

Daraasadaha dawooyinka casriga ah waxay caddeeyeen in Lingzhi uu kor u qaadi karo shaqada difaaca, iska caabbinta daalka, hagaajinta hurdada, iska caabbinta oksaydhka iyo inuu ka takhaluso xagjirnimada xorta ah, wuxuuna ilaalin karaa wadnaha, maskaxda, sambabada, beerka iyo kelyaha.Waxa loo isticmaalay daawaynta ama daawaynta adjuvant ee boronkiitada raaga, caabuqyada hab-mareenka neefsiga ee soo noqnoqda, neefta iyo cudurrada kale.

Sidee buu Lingzhi u ciyaara saameyntiisa ka hortagga fayraska?Waxaa guud ahaan la aqbalay in Lingzhi uu si aan toos ahayn u diido fayrasyada inay soo galaan jidhka bini'aadamka oo ay ku bataan oo ay dhaawacaan jidhka isaga oo kor u qaadaya habka difaaca jirka.

In kasta oo fayrasku aad u daran yahay, haddana ugu dambayntii waa la tirtiri doonaa iyada oo ay jirto difaac adag.Tan waxaa looga hadlay maqaalka "Lingzhi wuxuu xoojiyaa xasaanadda" oo lagu daabacay cadadka 58aad ee "GANODERMA" iyo maqaalka "AasaaskaGanoderma lucidumSi looga hortago Hargabka - Marka uu jiro qi ku filan oo caafimaad qaba gudaha, arrimaha pathogenic ma laha si ay u galaan jirka" oo lagu daabacay cadadka 46aad ee "GANODERMA".

Marka la soo koobo, mid ayaa ah in Lingzhi uu kor u qaadi karo hawlaha difaaca jidhka ee aan gaarka ahayn sida kor u qaadida fidinta, kala soocida iyo shaqada unugyada dendritic, kor u qaadida waxqabadka phagocytic ee macrophages mononuclear iyo unugyada dilaaga dabiiciga ah, iyo ka hortagga fayrasyada iyo bakteeriyada inay soo galaan aadanaha. jir.Marka labaad, Lingzhi waxa uu wanaajin karaa humoral iyo difaaca unugyada sida kor u qaadida wax soo saarka Immunoglobulin M (IgM) iyo Immunoglobulin G (IgG), kordhinta fidinta T lymphocytes iyo B lymphocytes, iyo kor u qaadida wax soo saarka cytokine interleukin-1 (IL-). 1), Interleukin-2 (IL-2) iyo interferon gamma (IFN-γ).

Xasaanadda humoral iyo difaaca unugga ayaa ka kooban difaaca qotodheer ee jirka ee ka hortagga fayraska iyo caabuqyada bakteeriyada.Waxay xidhi karaan bartilmaameedyo gaar ah si ay u sii difaacaan oo ay u baabi'iyaan fayrasyada iyo bakteeriyada soo weerarta jidhka.Marka shaqada difaacu hoos u dhacdo sababo kala duwan awgood, Lingzhi waxa kale oo uu wanaajin karaa shaqada difaaca.

Intaa waxa dheer, Lingzhi waxa kale oo uu yarayn karaa caabuqa uu keeno fayrasku iyo waxyeelada fayrasku u geysto xubnaha muhiimka ah sida sambabada, wadnaha, beerka, kelyaha, iyo ka hortagga ama yaraynta calaamadaha iyada oo loo marayo saamaynta anti-oxidant iyo xagjirnimada bilaashka ah.Caddadka 75-aad ee "GANODERMA", waxaa loo isticmaali karaa tixraac ah in muhiimada anti-oxidant iyo saamaynta xoqidda xagjirka ah ee xorta ahGanoderma lucidumka hortagga iyo daaweynta cudurrada waxaa si gaar ah looga hadlay maqaalka cinwaankiisu yahay "Lingzhi - Daaweynta Cudurro kala duwan oo isku mid ah".

Laga soo bilaabo 1980-meeyadii, waxaa jiray warbixino cilmi baaris ah oo ku saabsan saamaynta fayraska Lingzhi.Inta badan daraasaadkan waxay isticmaaleen moodooyinka unugyada uu haleelay fayraska gudaha vitro, iyo daraasado shaqsiyeed sidoo kale waxay isticmaaleen noocyada xoolaha ee caabuqa fayraska si ay u eegaan saamaynta fayraska Lingzhi.

Maqaallada tiirka ee uu daabacay Professor Zhibin Lin ee ku qoran 46, 58, iyo 75 ee "GANODERMA"

Fayraska ka hortagga cagaarshowga

Zhang Zheng iyo al.(1989) ayaa ogaadayGanoderma applanatum,Ganoderma atrumiyoGanoderma capensewaxay joojin kartaa fayraska cagaarshow B DNA polymerase (HBV-DNA polymerase), yaraynta HBV-DNA dib u soo celinta oo waxay joojin kartaa dheecaanka antigen-ka cagaarshowga B (HBsAg) ee unugyada PLC/PRF/5 (unugyada kansarka beerka ee bini'aadamka).

Cilmi-baadhayaashu waxay si dheeraad ah u arkeen waxtarka guud ee fayraska ka hortagga fayraska ee daawada ee qaabka cagaarshowga duck.Natiijadu waxay muujisay in maamulka afka eeGanoderma applanatum(50 mg/kg) laba jeer maalintii 10 maalmood oo isku xigta waxay yarayn kartaa saamaynta fayraska cagaarshow B DNA polymerase (DDNAP) iyo shinbiraha cagaarshow B DNA (DDNA) ee shinbiraha yaryar ee qaba fayraska cagaarshow B (DHBV), kaas oo taas ayaa tilmaamaysaGanoderma applanatumwaxay saameyn joojin ku leedahay DHBV ee jirka [1].

Li YQ iyo al.(2006) ayaa sheegay in kansarka beerka bini'aadamka ee unugyada unugyada HepG2 ee lagu wareejiyo HBV-DNA ay muujin karaan HBV antigen (HbsAg), HBV core antigen (HbcAg) iyo borotiinnada qaabdhismeedka fayraska HBV, waxayna si deggan u soo saari karaan qaybo fayraska cagaarshowga B ah.Ganoderic acid oo laga soo saaroG. lucidumDhaqan ahaan qiyaasta dhexdhexaadka ah ee ku-tiirsanaanta (1-8 μg / mL) waxay joojisay muujinta iyo soo saarista HBsAg (20%) iyo HBcAg (44%), taas oo soo jeedinaysa in ganoderic acid ay joojisay ku-noqoshada HBV ee unugyada beerka [2].

Fayraska ka hortagga hargabka

Zhu Yutong (1998) wuxuu ogaaday in gavage ama intraperitoneal lagu duroG. applanatumlaga soosaaray (ka-saarista biyaha ama faleebo qabow) waxay si weyn u kordhin kartaa heerka badbaadada iyo waqtiga badbaadada ee jiirarka qaba fayraska hargabka ee FM1, sidaas darteed waxay yeelanayaan saameyn ka hortag ah [3].

Mothana RA iyo al.(2003) waxay ogaatay in ganodermadiol, lucidadiol iyo applanoxidic acid G laga soo saaray oo laga nadiifiyay Yurub G. pfeifferi ay muujiyeen waxqabadyo ka hortagga fayraska hargabka A iyo fayraska herpes simplex nooca 1 (HSV-1).ED50 ee ganodermadiol si ay u ilaaliso unugyada MDCK (unugyada epithelioid ee ka soo jeeda kelyaha canine) ee ka hortagga caabuqa hargabka A waa 0.22 mmol/L.ED50 (50% qiyaasta wax ku oolka ah) ee ka ilaaliya unugyada Vero (unugyada kelyaha daayeer ee Afrikaan cagaaran) ka hortagga caabuqa HSV-1 waa 0.068 mmol/L.ED50 ee ganodermadiol iyo applanoxidic acid G ee ka dhanka ah infekshanka hargabka A waxay ahaayeen 0.22 mmol/L iyo 0.19 mmol/L, siday u kala horreeyaan [4].

La-dagaallanka HIV

Kim iyo al.(1996) wuxuu ogaaday in qaybta miisaanka kelli ee hoose eeG. lucidumSoosaarida biyaha jidhka miraha iyo qaybta dhexdhexaadka ah iyo alkaline ee laga soosaaray methanol waxay joojin kartaa faafitaanka fayraska difaaca jirka (HIV) [5].

El-Mekkawy iyo al.(1998) ayaa sheegay in triterpenoids ay ka go'doomeen soosaarka methanol eeG. lucidumJidhka miraha leh waxay leeyihiin saameyn anti-HIV-1 cytopathic waxayna muujinayaan waxqabadka xannibaadda ee borotiinka HIV laakiin wax saameyn ah kuma laha waxqabadka HIV-1 reverse transcriptase [6].

Min iyo al.(1998) waxay ogaadeen in ganoderic acid B, lucidumol B, ganodermanondiol, ganodermanontriol iyo ganolucidic acid A laga soosaarayG. lucidumkudka waxay leeyihiin saameyn adag oo ka hortag ah oo ku saabsan HIV-1 protease function [7].

Sato N iyo al.(2009) waxay ogaatay in triterpenoids-ka cusub ee loo yaqaan 'lanostane-nope' oo ogsijiin ah [ganodenic acid GS-2, 20-hydroxylucidenic acid N, 20(21) -dehydrolucidenic acid N iyo ganederol F] oo ka go'an jidhka mirahaGanoderma lucidumWaxay leeyihiin saameyn ka hortag ah oo ku saabsan HIV-1 protease oo leh dhexdhexaadinta dhexdhexaadinta dhexdhexaadka ah (IC50) sida 20-40 μm [8].

Yu Xiongtao iyo al.(2012) ayaa sheegay inG. lucidumSoosaarida biyaha spore waxay saameyn ku leedahay Simian Immunodeficiency Virus (SIV) kaas oo saameeya unugyada CEM × 174 ee xariiqda unugyada T lymphocyte, iyo IC50 waa 66.62 ± 20.21 mg / L.Shaqadeeda ugu weyni waa in ay ka joojiso SIV in ay soo gasho oo ay gasho unugyada marxaladda hore ee infekshanka fayraska SIV, waxayna yareyn kartaa heerka muujinta SIV capsid protein p27 [9].

Anti-Herpes Virus

Eo SK (1999) waxa uu diyaariyey laba qaybood oo biyo-milmi ah (GLhw iyo GLlw) iyo siddeed methanol laga soosaaray (GLMe-1-8) oo laga soo saaray mirahaG. lucidum.Dhaqdhaqaaqooda ka hortagga fayraska waxaa lagu qiimeeyay saameynta cytopathic (CPE) baaritaanka joojinta iyo baaritaanka yaraynta huurada.Waxaa ka mid ah, GLhw, GLMe-1, GLMe-2, GLMe-4, iyo GLMe-7 waxay muujinayaan saameyn cad oo ka hortagga fayraska herpes simplex nooca 1 (HSV-1) iyo nooca 2 (HSV-2), iyo sidoo kale stomatitis vesicular. fayraska (VSV) noocyada Indiana iyo New Jersey.Qiimaynta dhimista huurada, GLhw waxay joojisay samaynta huurada HSV-2 oo leh EC50 ee 590 iyo 580μg/mL ee unugyada Vero iyo HEp-2, iyo tusmooyinkeeda xulashada (SI) waxay ahaayeen 13.32 iyo 16.26.GLMe-4 ma aysan soo bandhigin cytotoxicity ilaa 1000 μg/ml, halka ay muujisay firfircoonida ka hortagga fayraska ee VSV New Jersey oo leh SI ka badan 5.43 [10].

OH KW iyo al.(2000) ka go'doomay borotiinka aashitada ku xidhan polysaccharide (APBP) oo ka yimid carpophores of Ganoderma lucidum.APBP waxay muujisay firfircoonida fayraska lidka ku ah HSV-1 iyo HSV-2 ee unugyada Vero ee EC50 ee 300 iyo 440μg/mL, siday u kala horreeyaan.APBP ma lahayn cytotoxicity unugyada Vero marka la uruurinayo 1 x 10(4) μg/ml.APBP waxay leedahay saameyn is-hortaag ah oo xakameynaya HSV-1 iyo HSV-2 marka lagu daro dawada ka hortagga Herpes Aciclovir, Ara-A ama interferonγ(IFN-γ) siday u kala horreeyaan [11,12].

Liu Jing iyo al.(2005) wuxuu ogaaday in GLP, polysaccharide ka go'anG. lucidummycelium, waxay joojin kartaa caabuqa unugyada Vero by HSV-1.GLP waxay xannibtay infekshanka HSV-1 marxaladaha hore ee caabuqa laakiin ma joojin karo isku-darka fayraska iyo makromolecules noolaha [13].

Iwatsuki K iyo al.(2003) waxay ogaatay in noocyo kala duwan oo triterpenoid ah laga soo saaray oo laga nadiifiyayGanoderma lucidumwaxay leeyihiin saameyn lid ku ah soo saarista fayraska Epstein-Barr ee antigen hore (EBV-EA) ee unugyada Raji (unugyada lymphoma bini'aadamka) [14].

Zheng DS iyo al.(2017) waxay ogaatay in shan triterpenoids laga soo saarayG. lucidum,oo ay ku jiraan ganoderic acid A, ganoderic acid B, iyo ganoderol B, ganodermanontriol iyo ganodermanondiol, waxay si weyn u yareeyaan suurtagalnimada kansarka naasopharyngeal (NPC) 5-8 F unugyada lagu beeray vitro, waxay muujinayaan saameyn weyn oo ka hortag ah labadaba EBV EA iyo CA firfircoonida iyo xakameynta telomerase hawlqabad.Natiijooyinkani waxay keeneen caddaynta ku-dhaqanka kuwanG. lucidumtriterpenoids ee daaweynta NPC [15].

Anti-Newcastle Disease Virus

Fayraska cudurka Newcastle waa nooc ka mid ah fayras hargabka avian-ka, kaas oo leh caabuq sare iyo dilaa shimbiraha dhexdooda.Shamaki BU iyo al.(2014) ogaaday inGanoderma lucidumSoosaarayaasha methanol, n-butanol iyo ethyl acetate waxay joojin karaan dhaqdhaqaaqa neuraminidase ee fayraska cudurka Newcastle [16].

Virus-ka-Dengue

Lim WZ iyo al.(2019) waxay ogaadeen in biyaha laga soo saaroG. lucidumqaabkeeda antler waxay joojisay dhaqdhaqaaqa DENV2 NS2B-NS3 protease ee 84.6 ± 0.7%, oo ka sarreeya kan caadiga ahG. lucidum[17]

Bharadwaj S iyo al.(2019) waxay adeegsatay hab baadhista farsamada ah iyo tijaabooyinka in vitro si loo saadaaliyo awooda triterpenoid ee shaqaynaysaGanoderma lucidumwaxaana la ogaaday in ganodermanontriol laga soo saarayGanoderma lucidumwaxay joojin kartaa fayraska dengue (DENV) NS2B -NS3 dhaqdhaqaaqa protease [18].

Anti-Enterovirus

Enterovirus 71 (EV71) waa cudur keenaha ugu weyn ee cudurada gacanta, cagaha iyo afka, taasoo keenta dhibaatooyin dilaa ah neerfayaasha iyo habdhiska ee carruurta.Si kastaba ha ahaatee, hadda ma jiraan dawooyin ka hortag fayrus ah oo kiliinikada la ansixiyey oo loo isticmaali karo ka hortagga iyo daaweynta caabuqan fayraska.

Zhang W iyo al.(2014) ogaaday in labadaGanoderma lucidumtriterpenoids (GLTs), oo ay ku jiraan Lanosta-7,9 (11), 24-trien-3-one,15;26-dihydroxy (GLTA) iyo Ganoderic acid Y (GLTB), muujiyaan waxqabadyo anti-EV71 muhiim ah oo aan cytotoxicity.

Natiijooyinku waxay soo jeediyeen in GLTA iyo GLTB ay ka hortagaan caabuqa EV71 iyaga oo la falgalaya qayb ka mid ah fayraska si ay u xannibaan galitaanka fayraska unugyada.Intaa waxaa dheer, isdhexgalka ka dhexeeya EV71 virion iyo xeryahooda waxaa saadaaliyay kombuyuutar molecular docking, taas oo muujisay in GLTA iyo GLTB laga yaabo inay ku xidhaan borotiinka capsid fayraska jeebka hydrophobic (F site), oo sidaas darteed laga yaabo inay xannibaan daboolka EV71.Waxaa intaa dheer, waxay muujiyeen in GLTA iyo GLTB ay si weyn u xakameeyaan ku-noqoshada fayraska RNA (vRNA) ee EV71 ku-celinta iyadoo la xirayo EV71 uncoating [19].

Soo koobid iyo dood
Natiijooyinka cilmi-baarista ee kor ku xusan waxay muujinayaan in Lingzhi, gaar ahaan triterpenoid-yada ku jira, ay saameyn joojin ku leedahay noocyo kala duwan oo fayras ah.Falanqaynta hordhaca ah waxay muujinaysaa in habka caabuqa ka hortagga fayraska ay ku lug leedahay joojinta xayeysiiska iyo dhexgalka fayraska ee unugyada, joojinta firfircoonida fayraska hore ee antigen, xannibaya dhaqdhaqaaqa qaar ka mid ah enzymes ee looga baahan yahay fayraska unugyada unugyada, xannibaya DNA-da fayraska ama RNA soo-celinta iyada oo aan la helin. cytotoxicity oo waxay leedahay saameyn isku-dhafan marka lagu daro daawooyinka fayraska ee la yaqaan.Natiijooyinkani waxay bixiyaan caddayn cilmi-baaris dheeraad ah oo ku saabsan saameynta fayraska Lingzhi triterpenoids.

Dib-u-eegis lagu sameeyo waxtarka caafimaad ee jira ee Lingzhi ee ka hortagga iyo daaweynta cudurrada fayraska, waxaan ogaanay in Lingzhi uu u beddeli karo calaamadaha fayraska cagaarshow B (HBsAg, HBeAg, anti-HBc) si xun uga hortagga iyo daawaynta cagaarshowga B. Laakiin marka laga reebo taas, daawaynta herpes zoster, condyloma acuminatum iyo AIDS oo ay weheliyaan dawooyinka fayraska ka hortaga, ma aynaan helin caddayn in Lingzhi uu si toos ah u joojin karo fayraska bukaanka.Waxtarka caafimaad ee Lingzhi ee cudurada fayrasku waxa laga yaabaa inay inta badan la xidhiidha saamaynta immunomodulatory, anti-oxidant iyo saamaynta xoqidda xagjirka ah ee xorta ah iyo saamaynta ay ku ilaalinayso dhaawaca xubnaha ama unugyada.(Mahad waxaa leh Professor Baoxue Yang oo saxay maqaalkan.)

Tixraacyo

1. Zhang Zheng, iyo al.Daraasadda Tijaabada ah ee 20 nooc oo Fungi Shiinaha ah oo ka dhan ah HBV.Journal of Beijing Medical University.1989, 21: 455-458.

2. Li YQ, iyo al.Hawlaha ka hortagga cagaarshowga B ee ganoderic acid oo ka yimidGanoderma lucidum.Biotechnol Lett, 2006, 28 (11): 837-841.

3. Zhu Yutong, et al. Saamaynta Ilaalinta ee Soo saaristaGanoderma applanatum(pers) pat.on Jiirarka uu ku dhacay Fayraska Hargab FM1. Journal of Guangzhou University of Chinese Medicine dhaqameed.1998, 15(3): 205-207.

4. Mothana RA, iyo al.Lanostanoid triterpenes ka-hortagga fayraska ee fangaskaGanoderma pfeifferi.Fitoterapia.2003, 74 (1-2): 177-180.

5. Kim BK.Waxqabadka Fayraska Kahortagga Difaaca-Aadamiga eeGanoderma lucidum.1996 International Ganoderma Symposium, Muxaadaro Gaar ah, Taipei.

6. El-Mekkawy S, iyo al.Anti-HIV iyo anti-HIV-protease walxaha kaGanoderma lucidum.Phytochemistry.1998, 49 (6): 1651-1657.

7. Min BS, iyo al.Triterpenes oo ka soo jeeda kudkaGanoderma lucidumiyo waxqabadkooda ka hortagga HIV-1 protease.Chem Pharm Bull (Tokyo).1998, 46 (10): 1607-1612.

8. Sato N, iyo al.Fayraska difaaca jirka ka-hortagga bini'aadamka-1 protease waxqabadka cusub ee nooca lanostane-triterpenoid kaGanoderma sinense.Chem Pharm Bull (Tokyo).2009, 57 (10): 1076-1080.

9. Yu Xiongtao, iyo al.Daraasad ku saabsan Saamaynta Ka-hortagga eeGanoderma lucidumku saabsan Fayraska Imunodeficiency ee Simian in vitro.Joornaalka Shiinaha ee Foomamka Caafimaadka Tijaabada .2012, 18 (13): 173-177.

10. Eo SK, iyo al.Dhaqdhaqaaqyada ka hortagga fayraska ee biyaha kala duwan iyo walxaha milmay ee methanol ee ka soocanGanoderma lucidum.J Ethnopharmacol.1999, 68 (1-3): 129-136.

11. Oh KW, iyo al.Dhaqdhaqaaqyada antiherpetic ee borotiinka acidic ee ku xidhan polysaccharide ka go'doonsanGanoderma lucidumkeligiis iyo isku-darka acyclovir iyo vidarabine.J Ethnopharmacol.2000, 72 (1-2): 221-227.

12. Kim YS, iyo al.Dhaqdhaqaaqyada antiherpetic ee borotiinka acidic ee ku xidhan polysaccharide ka go'doonsanGanoderma lucidumkeligiis iyo isku darka interferon.J Ethnopharmacol.2000, 72 (3): 451-458.

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14. Iwatsuki K, iyo al.Lucidenic acids P iyo Q, methyl lucidenate P, iyo triterpenoidyada kale ee fangaskaGanoderma lucidumiyo saameyntooda ka-hortagga ah ee firfircoonida Epstein-Barrvirus.J Nat Prod.2003, 66 (12): 1582-1585.

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★ Qoraalka asalka ah ee maqaalkan waxa ku qoray Shiinaha Professor Zhi-bin LIN waxaana u turjumay Ingiriisi Alfred Liu.Haddii uu jiro farqi u dhexeeya tarjumaada (Ingiriiska) iyo kan asalka ah (Shiineyska), Shiinaha asalka ah ayaa guulaysan doona.

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