I-Ganoderma lucidum ingathuthukisa ukungatheleleki kwabantu asebekhulile abanesifo senhliziyo.

Ukwehla kokuzivikela komzimba kuyisici esingenakugwenywa sokuguga, futhi asebekhulile abanesifo senhliziyo banezinkinga ezinkulu kakhulu zokuphazamiseka komzimba.Ake sibheke ukuthi kanjani “I-Ganoderma lucidumkuthinta ukusebenza kwamangqamuzana omzimba asebekhulile” eyanyatheliswa kuyi-Chinese Journal of Geriatrics ngo-1993.

Lo mbiko uveze ukuthi asebekhulile abaneminyaka yobudala engama-65 futhi abaphethwe yi-hyperlipidemia noma i-cardiocerebral atherosclerosis, ngemva kokuthatha izinsuku ezingu-30 ze-Ganoderma powder (amagremu angu-4.5 ngosuku), umsebenzi wamangqamuzana abulalayo wemvelo kanye nokugxila kwe-interferon.γfuthi i-interleukin 2 egazini yathuthukiswa kakhulu, futhi umphumela waqhubeka ngisho nangemva kokuba i-Ganoderma lucidum iyekwa izinsuku ezingu-10 (Umfanekiso 1).

Amangqamuzana abulalayo emvelo angabulala amaseli anamagciwane futhi akhiphe i-interferon γ;i-interferon γ ayivimbeli nje ukwanda kwegciwane kodwa futhi ikhuthaza ikhono lama-macrophages lokugwinya igciwane;i-interleukin 2 iyi-cytokine ekhiqizwa ama-T cell acushiwe futhi ayikwazi nje kuphela ukukhuthaza ukwanda kwama-T cell kodwa futhi yenze ama-B cell akhiqize amasosha omzimba.Ngakho-ke, ukuthuthukiswa kwalezi zinkomba ezintathu zokuzivikela kubaluleke kakhulu ekuthuthukiseni ikhono lokuvikela amasosha omzimba.
Lingzhiingathuthukisa umthamo we-antioxidant wabantu abaneminyaka ephakathi.

Ngo-2017, ithimba labacwaningi eliholwa nguSolwazi Wang Jinkun waseChung Shan Medical University lashicilela isifundo somtholampilo ku-Pharmaceutical Biology.Lolu cwaningo lusebenzise imodeli yokulawula i-placebo engahleliwe, eyimpumputhe ephindwe kabili ukuze iqhathanise abantu abaneminyaka engu-39 abanempilo ephakathi (iminyaka engu-40-54 ubudala) ngomehluko kumthamo we-antioxidant phakathi kwe-"Eating Lingzhi" kanye "Nokungadli i-Lingzhi".

IReishi amakhoweiqembu lithathe u-225 mg we-Ganoderma lucidum fruiting body extract preparation (equkethe u-7% we-ganoderic acid kanye no-6% we-polysaccharide peptide) nsuku zonke.Ngemuva kwezinyanga ze-6, izinkomba ezihlukahlukene ze-antioxidant zezifundo zanda (Ithebula 1) ngenkathi umsebenzi wabo wesibindi uthuthuka-amanani ajwayelekile we-AST ne-ALT ancipha ngo-42% no-27% ngokulandelana.Esikhundleni salokho, iqembu le-placebo alizange lenze "awukho umehluko omkhulu" uma kuqhathaniswa nangaphambili.
I-Ganoderma lucidum isiza izingane ukuthi zikhulise amasosha omzimba.

Nakuba ngokuvamile akunconywa ukuba izingane zidle i-Ganoderma lucidum, izingane zasenkulisa ziyiqembu labantu abangenwa kalula imikhuhlane nezifo, okubuye kube yikhanda langempela kubazali abaningi.Ucwaningo olushicilelwe ku-International Journal of Medicinal Mushrooms yi-Antioquia University ngonyaka ka-2018 ikakhulukazi lwahlola umphumela we-Ganoderma ekusebenzeni kokuzivikela komzimba kwezingane zasenkulisa, ngakho-ke yethulwa lapha ukuze uthole ireferensi yakho.

Ucwaningo lusebenzise imodeli yokulawula engahleliwe, eyimpumputhe ephindwe kabili, ye-placebo ukuze kuhlukaniswe izingane ezinempilo ezineminyaka engu-3 kuya kwengu-5 ubudala zibe yiqembu le-Ganoderma lucidum (izingane ezingu-60) kanye neqembu le-placebo (izingane ezingu-64).Iyogathi efanayo yanikezwa amaqembu amabili ezifundo nsuku zonke.Umehluko ukuthi iyogathi eqenjini le-Ganoderma iqukethe u-350 mg we-Ganoderma lucidum polysaccharide evela ku-Ganoderma lucidum mycelia ngokukhonza ngakunye.

Ngemva kwamasonto angu-12, inani lamaseli e-T eqenjini le-Ganoderma landa kakhulu, kodwa ingxenye ye-T cell subsets (CD4+ ne-CD8+) ayizange ithinteke (Ithebula 3).

Ngokuqondene ne-ALT, i-AST, i-creatinine nama-cytokines ahlobene nokuvuvukala okungavamile (okuhlanganisa i-IL-12 p70, IL-1β, IL-6, IL-10, ne-TNF-α) kanye namangqamuzana abulalayo emvelo kanye namasosha omzimba e-IgA, kwakungekho. umehluko omkhulu ezinambeni phakathi kwamaqembu amabili ngaphambi nangemuva kokuhlolwa.
Amasosha omzimba ebuntwaneni kufanele abhekane namagciwane ayi-10 kuya kwayi-15 athintana okokuqala minyaka yonke.Ngakho-ke, abacwaningi bakholelwa ukuthi i-Ganoderma lucidum polysaccharide ingakhuthaza ukwanda kwenani lama-T cell, isize amasosha omzimba ezingane zasenkulisa ukuthi asheshise ukuvuthwa.

Ukulala ngokwanele, ukudla okunomsoco, isimo sengqondo esijabulisayo nokuzivocavoca umzimba okusesilinganisweni kungathuthukisa amasosha omzimba.Kodwa-ke, inertia yomuntu, iminyaka, izifo kanye nokucindezeleka kokuphila kungavimbela ukugcinwa kokuzivikela okuhle.

I-Ganoderma lucidum inhle ekulweni yodwa, futhi ingabuye ihlanganiswe ibe incwadi kadokotela.Iphephile, ithembekile futhi ibanzi ekusebenzeni.Kokubili “akuqondile” (ngokubanzi ngokumelene nezinhlobonhlobo zamagciwane) kanye “nokuqondile” (kumelene namagciwane athile).Kungaba usizo ezidingweni zezempilo zabantu abaneminyaka ehlukene ngokuthuthukisa amasosha omzimba.

Kufanelekile ukulwa namagciwane angabonakali anokuzivikela okuhle okungabonakali.Uma umthamo omuhle we-antioxidant wengezwa, kuzoba nzima ukuthi amagciwane ahlaselayo enze amagagasi.

[Izithenjwa]
1. I-Tao Sixiang njll. Umphumela we-Ganoderma lucidum ekusebenzeni kwamangqamuzana omzimba asebekhulile.I-Chinese Journal of Geriatrics, i-1993, i-12 (5): 298-301.
2. Chiu HF, et al.I-Triterpenoids ne-polysaccharide peptides-enothisiweI-Ganoderma lucidum: ucwaningo lwe-crossover olulawulwa ngokungahleliwe, oluyimpumputhe oluphindwe kabili lwe-antioxidation nokusebenza kwe-hepatoprotective kumavolontiya anempilo.
I-Pharm Biol.2017, 55(1): 1041-1046.
3. I-Henao SLD, et al.Ukuhlolwa Komtholampilo Okungahleliwe Kokuhlolwa Kokuguqulwa Kwamasosha omzimba ngeYogathi Kuthuthukiswe ngama-β-Glucans avela e-Lingzhi noma e-Reishi Medicinal Mushroom,I-Ganoderma lucidum(Agaricomycetes), kuBantwana baseMedellin.Colombia.I-Int J Med Mushrooms.2018;20(8):705-716.