Hiki i ka Ganoderma lucidum ke hoʻonui i ka palekana o ka poʻe ʻelemakule me ka maʻi cardiovascular.

ʻO ka emi ʻana o ka pale ʻana he mea hiki ʻole ke pale ʻia o ka ʻelemakule, a ʻo ka poʻe ʻelemakule me ka maʻi cardiovascular he mau pilikia koʻikoʻi me nā maʻi immune.E nānā kākou pehea "ʻO Ganoderma lucidumpili i ka cellular immune function o ka poʻe ʻelemakule" i paʻi ʻia ma ka Chinese Journal of Geriatrics ma 1993.

Ua hōʻike ka hōʻike i ka poʻe ʻelemakule me ka awelika o 65 mau makahiki a me ka maʻi hyperlipidemia a i ʻole cardiocerebral atherosclerosis, ma hope o ka lawe ʻana i 30 mau lā o ka pauka Ganoderma (4.5 grams i kēlā me kēia lā), ka hana o nā pūnae pepehi maoli a me nā ʻano o ka interferon.γa me ka interleukin 2 i loko o ke koko ua hoʻomaikaʻi nui ʻia, a ua mau ka hopena ma hope o ka pau ʻana o ka Ganoderma lucidum no nā lā 10 (Figure 1).

Hiki i nā pūnaewele pepehi kanaka ke pepehi i nā pūnaewele i hoʻopiliʻia i ka maʻi a hūnā i ka interferon γ;ʻAʻole ka interferon γ wale nō ke kāohi i ka hoʻonui ʻana i ka maʻi maʻi akā hoʻoikaika pū i ka hiki o nā macrophages e hoʻopau i ka maʻi;ʻO ka interleukin 2 he cytokine i hana ʻia e nā pūnaewele T i hoʻōla ʻia a ʻaʻole hiki ke hoʻoikaika wale i ka hoʻonui ʻana o ka cell T akā hoʻoulu pū kekahi i nā cell B e hana i nā antibodies.No laila, he mea nui ka hoʻomaikaʻi ʻana o kēia mau hōʻailona immune ʻekolu no ka hoʻomaikaʻi ʻana i ka hiki antiviral o ka ʻōnaehana pale.
Lingzhihiki ke hoʻonui i ka mana antioxidant o nā poʻe waena.

Ma 2017, ua paʻi kahi hui noiʻi i alakaʻi ʻia e Professor Wang Jinkun o ke Kulanui Lapaʻau ʻo Chung Shan i kahi noiʻi lapaʻau ma Pharmaceutical Biology.Ua hoʻohana kēia haʻawina i kahi kumu hoʻohālike i hoʻohālikelike ʻia, pālua-makapō, placebo e hoʻohālikelike ai i 39 mau kānaka olakino waena (40-54 mau makahiki) ma ka ʻokoʻa o ka mana antioxidant ma waena o "Eating Lingzhi" a me "Not eating Lingzhi".

ʻO kaʻO Reishi mushroomUa lawe ka hui i 225 mg o Ganoderma lucidum fruiting body extract hoʻomākaukau (i loko o 7% ganoderic acid a me 6% polysaccharide peptide) i kēlā me kēia lā.Ma hope o 6 mau mahina, ua hoʻonui ʻia nā hōʻailona antioxidant like ʻole o nā kumuhana (Table 1) ʻoiai ka hoʻomaikaʻi ʻana o ka hana o ko lākou ate-ua emi iho nā kumu waiwai o AST a me ALT e 42% a me 27%.Akā, ua "ʻaʻohe ʻokoʻa koʻikoʻi" ka hui placebo i hoʻohālikelike ʻia ma mua.
Kōkua ʻo Ganoderma lucidum i nā keiki e hānai i kahi ʻōnaehana pale maikaʻi.

ʻOiai ʻaʻole ʻōlelo ʻia no nā keiki e ʻai i ka Ganoderma lucidum, ʻo nā keiki kula kamaliʻi he pūʻulu o nā poʻe i maʻalahi i ke anu a me nā maʻi, ʻo ia hoʻi kahi poʻo poʻo maoli no nā mākua he nui.ʻO ka noiʻi i paʻi ʻia ma ka International Journal of Medicinal Mushrooms e ke Kulanui ʻo Antioquia ma 2018 wale nō i loiloi i ka hopena o Ganoderma i ka hana immune o nā keiki preschool, no laila ua hoʻolauna ʻia ma aneʻi no kāu kuhikuhi.

Ua hoʻohana ke aʻo ʻana i kahi kumu hoʻohālike hoʻomalu, ʻelua makapō, placebo e hoʻokaʻawale i nā keiki olakino mai 3 a 5 mau makahiki i loko o ka hui Ganoderma lucidum (60 keiki) a me kahi hui placebo (64 keiki).Hāʻawi ʻia ka yogurt like i nā hui ʻelua o nā kumuhana i kēlā me kēia lā.ʻO ka ʻokoʻa, ʻo ka yogurt i loko o ka hui Ganoderma he 350 mg o Ganoderma lucidum polysaccharide mai Ganoderma lucidum mycelia i kēlā me kēia lawelawe.

Ma hope o nā pule he 12, ua hoʻonui nui ʻia ka nui o nā cell T i ka hui Ganoderma, akā ʻaʻole i hoʻopilikia ʻia ka hapa o nā subsets T cell (CD4 + a me CD8 +) (Table 3).

No ka ALT, AST, creatinine a me nā cytokines e pili ana i ka mumū ʻino (me IL-12 p70, IL-1β, IL-6, IL-10, a me TNF-α) a me nā mea pepehi maoli a me nā antibodies IgA, ʻaʻohe ʻokoʻa nui i nā helu ma waena o nā hui ʻelua ma mua a ma hope o ka hoʻāʻo.
ʻO ka ʻōnaehana pale i ka wā kamaliʻi e hana me 10 a 15 mau maʻi i hoʻopili ʻia no ka manawa mua i kēlā me kēia makahiki.No laila, manaʻo ka poʻe noiʻi hiki i ka Ganoderma lucidum polysaccharide ke hoʻoikaika i ka hoʻonui ʻana o ka heluna cell T, kōkua i ka ʻōnaehana pale ʻana o nā keiki preschool e hoʻolalelale i ke oʻo.

ʻO ka hiamoe kūpono, ka meaʻai kaulike, ke ʻano hauʻoli a me ka hoʻomaʻamaʻa haʻahaʻa hiki ke hoʻomaikaʻi i ka pale ʻana.Eia naʻe, hiki i ke kanaka inertia, nā makahiki, nā maʻi a me ke kaumaha o ke ola ke keʻakeʻa i ka mālama ʻana i ka palekana maikaʻi.

He maikaʻi ʻo Ganoderma lucidum i ka hakakā wale ʻana, a hiki ke hoʻohui pū ʻia i loko o kahi palapala.He palekana, hilinaʻi a piha i ka hana.ʻO ia ʻelua "kūpono ʻole" (e kūʻē i nā ʻano pathogens) a me "specific" (kūʻē i nā pathogens kikoʻī).Hiki ke kōkua i nā pono olakino o nā kānaka o nā makahiki like ʻole ma o ka hoʻoikaika ʻana i nā ʻōnaehana pale.

He kūpono ke kaua ʻana i nā germs i ʻike ʻole ʻia me ka palekana maikaʻi ʻole.Inā hoʻohui ʻia ka mana antioxidant maikaʻi, e paʻakikī i ka maʻi bacteria e hana i nā nalu.

[Nā Haʻawina]
1. Tao Sixiang etc. ʻO ka hopena o Ganoderma lucidum ma ka cellular immune function o ka poʻe kahiko.Ka Nupepa Kina o Geriatrics, 1993, 12(5): 298-301.
2. Chiu HF, et al.ʻO nā triterpenoids a me ka polysaccharide peptides i hoʻonui ʻiaʻO Ganoderma lucidum: kahi hoʻopaʻa ʻana i ka hoʻopaʻa ʻia ʻana o ka hoʻopaʻa ʻana o ka antioxidation a me ka hepatoprotective efficacy i nā mea manawaleʻa olakino.
Pharm Biol.2017, 55 (1): 1041-1046.
3. Henao SLD, et al.ʻO ka hoʻāʻo hoʻāʻo ʻokoʻa no ka loiloi ʻana o ka hoʻololi ʻana o ka Immune e Yogurt i hoʻonui ʻia me nā β-Glucans mai Lingzhi a i ʻole Reishi Medicinal Mushroom,ʻO Ganoderma lucidum(Agaricomycetes), i nā keiki mai Medellin.Kolomepia.Int J Med Halo.2018;20(8):705-716.