Ganoderma lucidum waxay kor u qaadi kartaa difaaca dadka waayeelka ah ee qaba cudurrada wadnaha iyo xididdada dhiigga.

Hoos u dhaca difaacu waa ifafaale lama huraan ah oo gabowga ah, iyo dadka waayeelka ah ee qaba cudurrada wadnaha iyo xididada waxay leeyihiin dhibaatooyin aad u daran oo ku saabsan cilladaha difaaca.Bal aan eegno sida “Ganoderma lucidumwaxay saamaysaa shaqada difaaca unugga ee waayeelka" oo lagu daabacay joornaalka Shiinaha ee Geriatrics ee 1993.

Warbixintu waxay tilmaantay in dadka waayeelka ah ee celceliska da'doodu tahay 65 sano jir oo ay la il daran yihiin hyperlipidemia ama wadnaha wadnaha, ka dib markii ay qaataan 30 maalmood oo budada Ganoderma ah (4.5 garaam maalintii), dhaqdhaqaaqa unugyada dilaaga dabiiciga ah iyo uruurinta interferon.γiyo interleukin 2 ee dhiiga ayaa si weyn loo hagaajiyay, saameyntuna way sii socotay xitaa ka dib markii Ganoderma lucidum la joojiyay maalmo 10 (Jaantus 1).

Unugyada dilaaga dabiiciga ah waxay dili karaan unugyada fayraska ku dhaca waxayna soo saaraan interferon γ;interferon γ ma aha oo kaliya in uu joojiyo faafitaanka fayraska laakiin sidoo kale wuxuu kor u qaadaa awoodda macrophages si uu u daboolo fayraska;interleukin 2 waa cytokine oo ay soo saaraan unugyada T-da ee firfircoon oo kaliya ma horumarin karaan kororka unugyada T laakiin sidoo kale waxay kicin karaan unugyada B si ay u soo saaraan unugyada difaaca jirka.Sidaa darteed, hagaajinta saddexdan tilmaame ee difaaca ayaa muhiimad weyn u leh hagaajinta awoodda fayraska ee habka difaaca jirka.
Lingzhiwaxay hagaajin kartaa awoodda antioxidant ee dadka da'da dhexe.

Sannadkii 2017, koox cilmi-baadhiseed oo uu hoggaaminayo Professor Wang Jinkun oo ka tirsan Jaamacadda Caafimaadka ee Chung Shan ayaa daabacday daraasad caafimaad oo ku saabsan Biyolojiyada Dawooyinka.Daraasadani waxay isticmaashay qaab kontorool oo kala sooc ah, laba-indho la'aan ah, si loo barbardhigo 39 dadka da'da dhexe ee caafimaadka qaba (40-54 sano jir) farqiga u dhexeeya awoodda antioxidant ee u dhexeeya "Cunitaanka Lingzhi" iyo " Cunista Lingzhi ".

Thelikaha Reishikooxdu waxay qaadatay 225 mg oo ah Ganoderma lucidum fruiting body diyaarinta (oo ka kooban 7% ganoderic acid iyo 6% polysaccharide peptide) maalin kasta.6 bilood ka dib, tilmaamayaasha kala duwan ee antioxidant ee maadooyinka ayaa kordhay (Shaxda 1) halka shaqadooda beerka ay soo hagaagtay - celceliska qiimaha AST iyo ALT ayaa hoos u dhacay 42% iyo 27% siday u kala horreeyaan.Taa baddalkeeda, kooxda placebo ma aysan soo marin "farqi weyn" marka loo eego sidii hore.
Ganoderma lucidum waxay ka caawisaa carruurta inay kobciyaan nidaam difaac wanaagsan.

In kasta oo aan guud ahaan lagu talinayn in carruurtu ay cunaan Ganoderma lucidum, carruurta dugsiga ka hor waa koox dad ah oo si fudud ugu nugul hargabka iyo cudurrada, taas oo sidoo kale ah madax-xanuun dhab ah waalidiin badan.Cilmi-baarista lagu daabacay joornaalka Caalamiga ah ee Mushrooms Daawooyinka ee Jaamacadda Antioquia kaliya 2018 ayaa inta badan qiimeysay saameynta Ganoderma ee shaqada difaaca carruurta ee dugsiga barbaarinta, sidaas darteed waxaa sidoo kale lagu soo bandhigay halkan tixraacaaga.

Daraasadu waxay isticmaashay qaab la kala soocay, laba-indho la'aan, qaabka kontoroolka placebo si loogu qaybiyo carruurta caafimaadka qabta ee da'doodu u dhaxayso 3 ilaa 5 sano jir ee Ganoderma lucidum group (60 carruur ah) iyo kooxda placebo (64 carruur ah).Isla caano fadhi ayaa la siin jiray labada kooxood ee maadooyinka maalin kasta.Farqiga ayaa ah in caano fadhi ee kooxda Ganoderma ay ka kooban tahay 350 mg oo Ganoderma lucidum polysaccharide ah oo laga helo Ganoderma lucidum mycelia halkii adeegba.

12 usbuuc ka dib, tirada unugyada T ee kooxda Ganoderma ayaa si aad ah u kordhay, laakiin saamiga unugyada T-yada (CD4+ iyo CD8+) ma saameynin (Shaxda 3).

Sida ALT, AST, creatinine iyo cytokines ee la xidhiidha caabuqa aan caadiga ahayn (oo ay ku jiraan IL-12 p70, IL-1β, IL-6, IL-10, iyo TNF-α) iyo sidoo kale unugyada dilaaga dabiiciga ah iyo unugyada difaaca IgA, ma jirin. Farqi weyn oo u dhexeeya tirada labada kooxood ka hor iyo ka dib imtixaanka.
Nidaamka difaaca ee carruurnimada waa inuu la tacaalaa 10 ilaa 15 fayras kuwaas oo la xiriira markii ugu horeysay sannad kasta.Sidaa darteed, cilmi-baarayaashu waxay aaminsan yihiin in Ganoderma lucidum polysaccharide ay kor u qaadi karto kororka tirada unugyada T-yada, waxay ka caawisaa nidaamka difaaca carruurta ee dugsiga barbaarinta si loo dardargeliyo qaan-gaarnimada.

Hurdo ku filan, nafaqo dheellitiran, niyadda farxadda leh iyo jimicsiga dhexdhexaadka ah ayaa hagaajin kara difaaca.Si kastaba ha ahaatee, la'aanta bini'aadamka, sanadaha, cudurrada iyo walbahaarka nolosha ayaa caqabad ku noqon kara ilaalinta difaaca wanaagsan.

Ganoderma lucidum waxay ku fiican tahay dagaalka kaligiis, waxaana sidoo kale lagu dari karaa warqad dhakhtar.Waa badbaado, la isku halayn karo iyo hawl dhammaystiran.Waa labadaba “aan gaar ahayn” (si balaadhan uga soo horjeeda cudur-sidaha kala duwan) iyo “gaar ah” (ka-hortagga cudur-sidaha gaarka ah).Waxay faa'iido u yeelan kartaa baahida caafimaad ee dadka da'doodu kala duwan tahay iyada oo kor loo qaado habka difaaca jirka.

Waa sax in lala dagaalamo jeermiska aan la arki karin oo leh difaac wanaagsan oo aan muuqan.Haddii awoodda antioxidant ee wanaagsan lagu daro, way ku adkaan doontaa bakteeriyada soo duushay inay samayso hirar.

[Tixraac]
1. Tao Sixiang iwm Saamaynta Ganoderma lucidum ee shaqada difaaca unugga ee waayeelka.Joornaalka Shiinaha ee Geriatrics, 1993, 12 (5): 298-301.
2. Chiu HF, iyo al.Triterpenoids iyo polysaccharide peptides-ku kobcayGanoderma lucidum: daraasad aan kala sooc lahayn, laba-indho-indho-indho la'aan ah oo la xakameeyey placebo oo ku saabsan antioxidation-keeda iyo waxtarkeeda hepatoprotective ee tabaruceyaasha caafimaadka qaba.
Pharm Biol.2017, 55 (1): 1041-1046.
3. Henao SLD, iyo al.Tijaabada Caafimaad ee Randomized ee Qiimaynta Wax-ka-beddelka Difaaca ee Yogurt Lagu xoojiyey β-Glucans Lingzhi ama Reishi Mushroom Daawo,Ganoderma lucidum(Agaricomycetes), gudaha Carruurta Medellin.Kolombiya.Int J Med Mushrooms.2018;20 (8): 705-716.