Ganoderma lucidum inogona kuwedzera kudzivirirwa kwevakwegura vane chirwere chemwoyo.

Kuderera kwehutachiona chinhu chisingadzivisiki chekukwegura, uye vakwegura vane chirwere chemwoyo vane zvinetso zvakakomba zvakanyanya nezvirwere zvekudzivirira.Ngationei kuti sei “Ganoderma luciduminokanganisa mashandiro emasero emuviri evakwegura” rakabudiswa muChinese Journal of Geriatrics muna 1993.

Mushumo wacho wakaratidza kuti vakwegura vane avhareji yezera remakore 65 uye vanotambura ne hyperlipidemia kana cardiocerebral atherosclerosis, mushure mekutora mazuva makumi matatu eGanoderma powder (4.5 gramu pazuva), basa remasero anouraya echisikigo uye kuwedzera kwe interferon.γuye interleukin 2 muropa yakagadziridzwa zvakanyanya, uye mhedzisiro yacho yakaramba iripo kunyange mushure mekunge Ganoderma lucidum yakabviswa kwemazuva 10 (Mufananidzo 1).

Masero anouraya echisikigo anogona kuuraya masero ane hutachiona uye anoburitsa interferon γ;interferon γ haisi kungodzivisa kupararira kwehutachiwana asiwo inokurudzira kukwanisa kwema macrophages kuvhara utachiona;interleukin 2 is a cytokine inogadzirwa neT masero akagadzirwa uye haingogone kukurudzira T cell kuwanda asiwo kukurudzira B masero kugadzira masoja ekudzivirira chirwere.Naizvozvo, kuvandudzwa kweaya matatu ekudzivirira ekudzivirira ane kukosha kukuru pakuvandudza simba rekudzivirira immune system.
Lingzhiinogona kuvandudza iyo antioxidant kugona kwevanhu vepakati-kati.

Muna 2017, timu yekutsvagisa inotungamirwa naProfessor Wang Jinkun weChung Shan Medical University yakaburitsa chidzidzo chekiriniki muPharmaceutical Biology.Ichi chidzidzo chakashandisa randomized, kaviri-mapofu, placebo control model kuenzanisa 39 vane hutano hwevanhu vepakati-kati (40-54 yemakore) pamusiyano we antioxidant simba pakati pe "Kudya Lingzhi" uye "Kusadya Lingzhi".

TheReishi mushroomboka rakatora 225 mg yeGanoderma lucidum fruiting body extract gadziriro (ine 7% ganoderic acid uye 6% polysaccharide peptide) zuva rega rega.Mushure memwedzi ye6, zviratidzo zvakasiyana-siyana zve-antioxidant zvezvidzidzo zvakawedzera (Tafura 1) apo chiropa chavo chakavandudza-chiyero chemaitiro eAST uye ALT chakaderera ne42% uye 27% maererano.Pane kudaro, boka re placebo rakawana "hapana mutsauko wakakosha" zvichienzaniswa nekare.
Ganoderma lucidum inobatsira vana kukurudzira immune system yakanaka.

Kunyange zvazvo zvisingawanzokurudzirwi kuti vana vadye Ganoderma lucidum, vana vechikoro iboka revanhu vari nyore kubatwa nedzihwa uye zvirwere, izvo zvinovawo musoro chaiwo kuvabereki vakawanda.Tsvagiridzo yakaburitswa muInternational Journal yeMedicinal Mushrooms neAntioquia University ichangopfuura muna 2018 yakanyatso ongorora maitiro eGanoderma pane immune mashandiro evana vekireshi, saka inounzwawo pano kuti utarise.

Chidzidzo chacho chakashandisa maitiro, maviri-mapofu, e-placebo control model kuti aparadzanise vana vane utano vane makore 3 kusvika ku5 makore muGanoderma lucidum boka (vana makumi matanhatu) uye boka re placebo (64 vana).Iyo yogati imwechete yakapihwa kumapoka maviri ezvidzidzo zuva rega rega.Musiyano ndewekuti iyo yogati muboka reGanoderma ine 350 mg yeGanoderma lucidum polysaccharide kubva kuGanoderma lucidum mycelia pakushumira.

Mushure memavhiki e12, nhamba yemasero eT muboka reGanoderma yakawedzera zvakanyanya, asi chikamu cheT cell subsets (CD4 + uye CD8 +) haina kukanganiswa (Tafura 3).

Kana iri ALT, AST, creatinine uye cytokines zvine chokuita nekuputika kusina kujairika (kusanganisira IL-12 p70, IL-1β, IL-6, IL-10, uye TNF-α) pamwe chete nemasero emuurayi echisikigo uye IgA antibodies, pakanga pasina. mutsauko mukuru wenhamba pakati pemapoka maviri pamberi uye mushure mebvunzo.
Iwo immune system muhudiki inofanirwa kutarisana nemavhairasi gumi kusvika gumi nemashanu ari kusangana kekutanga gore rega rega.Naizvozvo, vaongorori vanotenda kuti Ganoderma lucidum polysaccharide inogona kusimudzira kuwanda kweT cell vanhu, kubatsira immune system yevana vechikoro kuti ikurumidze kukura.

Kurara kwakakwana, kudya kwakadzikama, kufara uye kurovedza muviri zvine mwero kunogona kuvandudza hutachiona.Zvisinei, inertia yevanhu, makore, zvirwere uye kushungurudzika kwehupenyu zvinogona kukanganisa kuchengetedza kwekudzivirira kwakanaka.

Ganoderma lucidum yakanaka pakurwa yega, uye inogona zvakare kusanganiswa kuita chirevo.Yakachengeteka, yakavimbika uye yakazara mukushanda.Zvose "zvisina-kunanga" (zvakanyanya kurwisana nemarudzi akasiyana-siyana ezvirwere) uye "zvakananga" (zvinopesana nehutachiona chaihwo).Inogona kubatsira kune zvinodiwa zvehutano zvevanhu vezera rakasiyana kuburikidza nekuwedzera masoja emuviri.

Zvakakodzera kurwisa utachiona husingaoneki husingaonekwi hwakanaka.Kana yakanaka antioxidant simba yakawedzerwa, zvichave zvakaoma kuti mabhakitiriya anopinda aite mafungu.

[Mazita]
1. Tao Sixiang etc. Mhedzisiro yeGanoderma lucidum pane cellular immune function yevakwegura.Chinese Journal of Geriatrics, 1993, 12 (5): 298-301.
2. Chiu HF, nevamwe.Triterpenoids uye polysaccharide peptides-yakafumiswaGanoderma lucidum: a randomized, double-blind-placebo-controlled controlled crossover study of its antioxidation uye hepatoprotective efficacy mune vanozvipira vane utano.
Nhoroondo ye Pharm Biol.2017, 55(1): 1041-1046.
3. Henao SLD, nevamwe.Randomized Clinical Trial yekuongororwa kweImmune Modulation neYogurt Yakagadzirwa ne β-Glucans kubva kuLingzhi kana Reishi Medicinal Mushroom,Ganoderma lucidum(Agaricomycetes), muVana vanobva kuMedellin.Korombiya.Int J Med Howa.2018;20(8):705-716.