I-Ganoderma lucidum inokunyusa ukhuseleko lwabantu abadala abanesifo senhliziyo.

Ukuhla kwe-immunity yinto engenakuphepheka yokuguga, kwaye abantu abadala abanesifo se-cardiovascular disease baneengxaki ezinzulu zokuphazamiseka komzimba.Makhe sijonge ukuba njani “I-Ganoderma lucidumichaphazela ukusebenza kweseli yomzimba yokuzikhusela kwabantu abadala” eyapapashwa kwiShayina Journal of Geriatrics ngowe-1993.

Ingxelo yabonisa ukuba abantu abadala abaneminyaka eyi-65 ubudala kunye nokuxhatshazwa kwe-hyperlipidemia okanye i-cardiocerebral atherosclerosis, emva kokuthatha iintsuku ze-30 ze-Ganoderma powder (i-4.5 grams ngosuku), umsebenzi weeseli ezibulalayo zendalo kunye nokugxilwa kwe-interferon.γkunye ne-interleukin 2 egazini yaphuculwa kakhulu, kwaye umphumo uqhubekile nangemva kokuba i-Ganoderma lucidum iyekwa iintsuku ze-10 (Umfanekiso 1).

Iiseli ezibulalayo zendalo zinokubulala iiseli ezosulelwe yintsholongwane kwaye zikhuphe i-interferon γ;i-interferon γ ayithinteli nje ukwanda kwentsholongwane kodwa ikhuthaza amandla e-macrophages ukuba afake intsholongwane;I-interleukin 2 yi-cytokine eveliswa ziiseli ze-T ezisebenzayo kwaye ayikwazi ukukhuthaza ukwanda kweeseli ze-T kodwa iphinda ikhuthaze iiseli ze-B ukuba zivelise amajoni omzimba.Ke ngoko, ukuphuculwa kwezi zalathisi zintathu zokhuselo lomzimba kubaluleke kakhulu ekuphuculeni isakhono se-antiviral se-immune system.
Lingzhiinokuphucula amandla e-antioxidant kubantu abaneminyaka ephakathi.

Kwi-2017, iqela lophando elikhokelwa nguNjingalwazi uWang Jinkun weChung Shan Medical University lipapashe isifundo seklinikhi kwi-Pharmaceutical Biology.Olu pho nonongo lusebenzise imodeli yokulawula i-randomized, i-double-blind, i-placebo ukuthelekisa abantu abangama-39 abanempilo ephakathi (iminyaka eyi-40-54 ubudala) kumahluko kwi-antioxidant umthamo phakathi kwe-"Eating Lingzhi" kunye "Nokutya i-Lingzhi".

IReishi mushroomiqela lithathe i-225 mg ye-Ganoderma lucidum fruiting isicatshulwa somzimba wokulungiselela (iqulethe i-7% ye-ganoderic acid kunye ne-6% ye-polysaccharide peptide) yonke imihla.Emva kweenyanga ze-6, izibonakaliso ezahlukeneyo ze-antioxidant zezifundo zanda (Itheyibhile 1) ngelixa umsebenzi wabo wesibindi uphuculwe-imilinganiselo ye-AST kunye ne-ALT yehla nge-42% kunye ne-27% ngokulandelanayo.Endaweni yoko, iqela le-placebo liye lenza “akukho mahluko ubalulekileyo” xa kuthelekiswa nangaphambili.
I-Ganoderma lucidum inceda abantwana ukuba bakhulise amajoni omzimba afanelekileyo.

Nangona ngokuqhelekileyo akukhuthazwa ukuba abantwana batye i-Ganoderma lucidum, abantwana basenkulisa liqela labantu abangenwa lula yimikhuhlane kunye nezigulo, nto leyo eyintloko yokwenyani kubazali abaninzi.Uphando olupapashwe kwi-International Journal of Medicinal Mushrooms yiYunivesithi yase-Antioquia nje ngo-2018 ikakhulu ivavanye isiphumo se-Ganoderma kumsebenzi wokuzivikela komzimba wabantwana abasaqala isikolo, ngoko ke yaziswa apha ukuze ubhekiselele kuyo.

Uphononongo lusebenzise imodeli yokulawula i-randomized, i-double-blind-blind, i-placebo ukwahlula abantwana abanempilo abaneminyaka eyi-3 ukuya kwi-5 iminyaka ukuya kwiqela le-Ganoderma lucidum (abantwana be-60) kunye neqela le-placebo (abantwana be-64).I yoghurt efanayo yayinikwa amaqela amabini ezifundo yonke imihla.Umahluko kukuba i-yogurt kwiqela le-Ganoderma iqulethe i-350 mg ye-Ganoderma lucidum polysaccharide esuka kwi-Ganoderma lucidum mycelia ngokukhonza.

Emva kweeveki ze-12, inani leeseli ze-T kwiqela le-Ganoderma landa kakhulu, kodwa umlinganiselo we-T cell subsets (CD4 + kunye ne-CD8 +) awuchaphazelekanga (iThebhile 3).

Ngokuphathelele i-ALT, i-AST, i-creatinine kunye ne-cytokines ehambelana nokuvuvukala okungaqhelekanga (kubandakanya i-IL-12 p70, IL-1β, IL-6, IL-10, kunye ne-TNF-α) kunye neeseli ezibulalayo zendalo kunye ne-IgA antibodies, kwakungekho umahluko omkhulu kumanani phakathi kwamaqela amabini ngaphambi nasemva kovavanyo.
Amajoni omzimba ebuntwaneni kufuneka ajongane neentsholongwane ezili-10 ukuya kwezili-15 ezidibana okokuqala minyaka le.Ke ngoko, abaphandi bakholelwa ukuba i-Ganoderma lucidum polysaccharide inokukhuthaza ukwanda kwabantu beeseli ze-T, incede amajoni omzimba wabantwana basesikolweni ukukhawulezisa ukukhula.

Ukulala ngokwaneleyo, ukutya okunesondlo, umoya owonwabileyo kunye nokuzivocavoca umzimba okuphakathi kunokuphucula ukungakhuseleki.Nangona kunjalo, inertia yabantu, iminyaka, izifo kunye noxinzelelo lobomi kunokuthintela ukugcinwa kokugonywa kakuhle.

I-Ganoderma lucidum ilungile ekulweni yodwa, kwaye inokudityaniswa ibe ngummiselo.Ikhuselekile, ithembekile kwaye ibanzi ekusebenzeni.Yomibini “ayiyodwa” (ngokubanzi ngokuchasene neentlobo ngeentlobo zeentsholongwane) kunye “nokuthile” (kunxamnye nentsholongwane ethile).Inokuba luncedo kwiimfuno zempilo zabantu abakubudala obahlukeneyo ngokonyusa amajoni omzimba.

Kufanelekile ukulwa neentsholongwane ezingabonakaliyo kunye ne-immunity engabonakaliyo engabonakaliyo.Ukuba i-antioxidant enamandla yongezwa, kuya kuba nzima ukuba iibhaktheriya ezihlaselayo zenze amaza.

[Iimbekiselo]
1. I-Tao Sixiang njl. Umphumo weGanoderma lucidum kwi-cell immune function yabantu abadala.Ijenali yaseTshayina yeGeriatrics, i-1993, i-12 (5): 298-301.
2. Chiu HF, et al.I-Triterpenoids kunye ne-polysaccharide peptides-etyebileyoI-Ganoderma lucidum: i-randomized, i-double-blind-blind-blind-blind-controlled-placebo-controlled controlled crossover study of its antioxidation kunye ne-hepatoprotective efficacy kumavolontiya anempilo.
Pharm Biol.2017, 55 (1): 1041-1046.
3. Henao SLD, et al.Uvavanyo lweklinikhi olungenamkhethe loVavanyo lwe-Immune Modulation yi-Yoghurt Eyotyisiweyo nge-β-Glucans evela e-Lingzhi okanye kwi-Mushroom ye-Medicinal ye-Reishi,I-Ganoderma lucidum(Agaricomycetes), kuBantwana abavela eMedellin.Kholambiya.Int J Med Mushrooms.2018;20(8):705-716.