Ganoderma lucidum nwere ike ịkwalite mgbochi nke ndị agadi nwere ọrịa obi.

Mbelata nke mgbochi bụ ihe a na-apụghị izere ezere nke ịka nká, na ndị agadi nwere ọrịa obi na-enwe nsogbu dị njọ karị na nsogbu ndị na-alụso ọrịa ọgụ.Ka anyị lee otú”Ganoderma lucidumna-emetụta ọrụ mgbochi cellular nke ndị agadi” nke e bipụtara na Chinese Journal of Geriatrics na 1993.

Akụkọ ahụ kwuru na ndị agadi na nkezi afọ 65 na-arịa hyperlipidemia ma ọ bụ cardiocerebral atherosclerosis, mgbe ha were ụbọchị 30 nke Ganoderma ntụ ntụ (gram 4.5 kwa ụbọchị), ọrụ nke mkpụrụ ndụ na-egbu egbu na ntinye nke interferon.γna interleukin 2 n'ime ọbara na-eme ka ọ dịkwuo mma, na mmetụta ahụ nọgidere na-adịru ọbụna mgbe Ganoderma lucidum kwụsịrị maka ụbọchị 10 (Nyocha 1).

Mkpụrụ ndụ na-egbu egbu nwere ike igbu mkpụrụ ndụ ndị bu nje virus wee zoo interferon γ;interferon γ ọ bụghị naanị na-egbochi mgbasa nje, kamakwa ọ na-akwalite ikike nke macrophages ikpuchi nje ahụ;interleukin 2 bụ cytokine nke mkpụrụ ndụ T na-arụ ọrụ na-emepụta na ọ bụghị nanị na-akwalite mmụba cell T kamakwa ime ka mkpụrụ ndụ B mepụta ọgwụ mgbochi.Ya mere, mmelite nke ihe ngosi atọ ndị a na-adịghị ahụkebe dị oke mkpa maka imeziwanye ikike mgbochi nke usoro ahụ ji alụso ọrịa ọgụ.
Lingzhinwere ike melite ikike antioxidant nke ndị agadi.

Na 2017, otu nyocha nke Prọfesọ Wang Jinkun nke Mahadum Ahụike Chung Shan duuru bipụtara ọmụmụ ụlọ ọgwụ na Biology Pharmaceutical.Ọmụmụ ihe a na-eji usoro nchịkwa, nke abụọ kpuru ìsì, ebe a na-achịkwa ebebo iji tụnyere 39 ndị agadi nọ n'etiti ahụ ike (40-54 afọ) na ọdịiche dị na ikike antioxidant dị n'etiti "Iri Lingzhi" na "adịghị eri Lingzhi".

NkeReishi eroOtu a were 225 mg nke Ganoderma lucidum fruiting body extract nkwadebe (nwere 7% ganoderic acid na 6% polysaccharide peptide) kwa ụbọchị.Mgbe ọnwa 6 gachara, ihe ngosi antioxidant dị iche iche nke isiokwu ndị ahụ mụbara (Table 1) ebe ọrụ imeju ha na-abawanye - nkezi ụkpụrụ AST na ALT belatara site na 42% na 27% n'otu n'otu.Kama nke ahụ, otu placebo nwere "enweghị nnukwu ọdịiche" ma e jiri ya tụnyere nke mbụ.
Ganoderma lucidum na-enyere ụmụaka aka ịkwalite usoro ahụ ji alụso ọrịa ọgụ dị mma.

Ọ bụ ezie na a naghị atụ aro ka ụmụaka rie Ganoderma lucidum, ụmụaka ụlọ akwụkwọ ọta akara bụ otu ndị mmadụ na-enwekarị oyi na ọrịa, nke bụkwa ezigbo isi ọwụwa nye ọtụtụ ndị nne na nna.Nnyocha e bipụtara na International Journal of Medicinal Mushrooms nke Mahadum Antioquia dị naanị na 2018 tụlere nsonaazụ Ganoderma na ọrụ mgbochi nke ụmụaka ụlọ akwụkwọ ọta akara, yabụ ewebata ya ebe a maka ntụaka gị.

Ọmụmụ ihe a na-eji usoro nchịkwa, nke abụọ kpuru ìsì, ebe a na-achịkwa ebebo iji kewaa ụmụaka ahụike dị afọ 3 ruo 5 n'ime ìgwè Ganoderma lucidum (ụmụ 60) na placebo otu (ụmụ 64).A na-enye otu yogọt otu ihe ahụ kwa ụbọchị.Ihe dị iche bụ na yogọt na otu Ganoderma nwere 350 mg nke Ganoderma lucidum polysaccharide sitere na Ganoderma lucidum mycelia kwa nri.

Mgbe izu iri na abụọ gachara, ọnụ ọgụgụ nke mkpụrụ ndụ T na Ganoderma mụbara nke ukwuu, mana emetụtaghị akụkụ nke T cell subsets (CD4+ na CD8+) (Table 3).

Banyere ALT, AST, creatinine na cytokines metụtara mbufụt na-adịghị mma (gụnyere IL-12 p70, IL-1β, IL-6, IL-10, na TNF-α) yana mkpụrụ ndụ na-egbu egbu na ọgwụ mgbochi IgA, ọ nweghị. nnukwu ọdịiche dị na ọnụọgụ n'etiti otu abụọ ahụ tupu ule na mgbe ule gasịrị.
Usoro ahụ ji alụso ọrịa ọgụ na nwata aghaghị ịlụso nje virus 10 ruo 15 na-akpakọrịta na nke mbụ kwa afọ.Ya mere, ndị na-eme nchọpụta kwenyere na Ganoderma lucidum polysaccharide nwere ike ịkwalite mmụba nke ọnụ ọgụgụ T cell, nyere aka n'ịgwọ ọrịa ụmụaka nke ụlọ akwụkwọ ọta akara iji mee ka ntozu okè.

Ịra ụra nke ọma, nri kwesịrị ekwesị, ọnọdụ obi ụtọ na mmega ahụ na-agafeghị oke nwere ike imeziwanye ihe nchebe.Otú ọ dị, mmadụ inertia, afọ, ọrịa na nrụgide nke ndụ nwere ike igbochi mmezi nke ọma mgbochi.

Ganoderma lucidum dị mma n'ịlụ ọgụ naanị ya, enwere ike jikọta ya na ndenye ọgwụ.Ọ bụ nchekwa, ntụkwasị obi na nke zuru oke na ọrụ.Ọ bụ ma “na-abụghị nke a kapịrị ọnụ” (na-emegide ụdị nje dị iche iche) na “kpọmkwem” (megide pathogens kpọmkwem).Ọ nwere ike ịba uru maka mkpa ahụike nke ndị nọ n'afọ ndụ dị iche iche site na ịkwalite usoro ahụ ji alụso ọrịa ọgụ.

Ọ bụ ihe ziri ezi ịlụ ọgụ megide nje ndị a na-adịghị ahụ anya nke nwere ezigbo ihe nchebe na-adịghị ahụ anya.Ọ bụrụ na agbakwunyere ikike antioxidant dị mma, ọ ga-esiri nje bacteria na-awakpo ike ime ebili mmiri.

[Ntụaka]
1. Tao Sixiang wdg Mmetụta nke Ganoderma lucidum na ọrụ mgbochi cellular nke ndị agadi.Akwụkwọ akụkọ China nke Geriatrics, 1993, 12 (5): 298-301.
2. Chiu HF, et al.Triterpenoids na polysaccharide peptides bara ụbaGanoderma lucidum: a randomized, abụọ kpuru placebo-achịkwa crossover ọmụmụ nke antioxidation na hepatoprotective arụmọrụ na ndị ọrụ afọ ofufo ahụ ike.
Pharm Biol.2017, 55 (1): 1041-1046.
3. Henao SLD, et al.Ọnwụnwa ụlọ ọgwụ Randomized maka nyocha nke Modulation nke mgbochi site na Yogurt mebere ya na β-Glucans sitere na Lingzhi ma ọ bụ ero ọgwụ Reishi,Ganoderma lucidum(Agaricomycetes), na ụmụaka si Medellin.Colombia.Int J Med ero.2018;20 (8): 705-716 .