Kubvumbi 12, 2017 / Yunivhesiti yeBrawijaya / Heart International

Chinyorwa/ Wu Tingyao

Yenguva refu-yakakwirira-cholesterol yekudya inogona kutungamirira nyore kune isina kujairika ropa lipids, uye kwenguva yakareba isina kujairika ropa lipids inogona kutungamirira kuatherosclerosis.Zvisinei, kanaGanoderma lucidumpolysaccharides inopindira, kunyange kana lipids yeropa ichiri isina kujairika, njodzi yeatherosclerosis inogona kuderedzwa.

"Heart International" yakaburitsa chirevo kubva kuYunivhesiti yeBrawijaya muIndonesia muna 2017, zvichiratidza izvozvoGanoderma lucidumpolysaccharide peptides (protein-rich β-D-glucan yakatorwa kubvaGanoderma lucidum) kuva nekudzivirira uku.

Multiple mhedzisiro kurwisa atherosclerosis

Vatsvakurudzi vakadyisa makonzo ane high-cholesterol kudya kwemavhiki e12.Mapoka matatu emakonzo aidyiwa panguva imwe chete neakaderera, epakati uye akakwira madhizi (50, 150, 300 mg / kg) yeGanoderma lucidumpolysaccharide peptides (PsP) kugadzirira, iyo ine 20%Ganoderma lucidumpolysaccharide peptides, mumavhiki ekupedzisira e4 ekuedza.

Mushure mekuedza, hutano hweropa remakonzo hwakaongororwa kuburikidza nezviratidzo zvina, uye zvinotevera zvakawanikwa maererano nemakonzo akadya.Ganoderma lucidumpolysaccharide peptides:

1. Kusanganiswa kwemahara radicals H2O2 muserum yakanyanya kuderera - iyo yakaderera-density lipoprotein cholesterol (LDL-C) yakaunganidzwa mumadziro emidziyo yeropa yakasvibiswa nemahara radicals, iyo ndiyo nhanho yekutanga mukuumbwa kweatherosclerosis.Kana mahara radicals ichiderera, mukana weatherosclerosis unodzikira.

2. Kudzivirirwa kweIL-10, anti-inflammatory cytokine, inoderedzwa - zvinoreva kuti chiyero chekuputika chinyoro, saka hapana chikonzero che IL-10 yakawanda yekurwisana nekuputika.

3. Nhamba ye "endothelial progenitor cells" inogona kushandiswa kugadzirisa masvingo emidziyo yeropa yakakanganiswa yakawedzera - endothelial progenitor masero anotenderera mumuviri wose neropa anogona kugadzirisa masvingo emidziyo yeropa yakakanganiswa neoxidation uye kuzvimba.Nokudaro, kuwedzera kwe endothelial progenitor masero kunoratidza kuti mukana wekugadzirisa rusvingo rwakakanganisika rwemudziyo weropa unowedzera, uye mukana wekuwedzera kushanduka mu atherosclerosis wakaderera.

4. Ukobvu hwemadziro emukati weaorta (intima uye midhiya) iri pedyo neyakajairwa - chikamu chemuchinjikwa chemudziyo we arterial chinogona kugoverwa muzvikamu zvitatu kubva mukati kusvika kunze: rusvingo rwemudziyo weropa unosangana. nekuyerera kweropa kunonzi intima, iyo inoumbwa ne endothelial masero;chikamu chepakati chinoumbwa nemhasuru yakatsetseka inonzi media.Aya maviri akaturikidzana evascular tissues ndiyo inonyanya kukosha nzvimbo dzeatherosclerosis.Nokudaro, kana kukora kwezvikamu zviviri zvaswedera kune zvakajairika, zvinoreva kuti tsinga dzine hutano hwakanaka.

Yemahara radical concentration mu rat serum

[Cherechedza] H2O2 imhando yemahara radical.Iyo yakadzikira iyo yekuisa kwayo, iyo isinganyanyi kuve iri kuita atherosclerosis.(Kudhirowa/Wu Tingyao, kunobva data/Moyo Int. 2017; 12(1): e1-e7.)

Iko kusangana kwe-anti-inflammatory cytokine mune rat serum

[Cherechedza] Kana iyo inorwisa-kuzvimba IL-10 muserum isina kunyanya kukwirira, zvinoreva kuti kuzvimba kwemadziro etsinga yeropa kunogona kunge kusiri kwakanyanya, uye njodzi yeatherosclerosis yakaderedzwa zvakare.(Kudhirowa/Wu Tingyao, kunobva data/Moyo Int. 2017; 12(1): e1-e7.)

Nhamba ye endothelial progenitor masero muropa remakonzo

[Cherechedza] Endothelial progenitor masero anogona kugadzirisa madziro etsinga akakuvadzwa.Kana nhamba yavo ichiwedzera, zvinoreva kuti njodzi yeatherosclerosis inoderedzwa kana inogona kunonoka.(Kudhirowa/Wu Tingyao, kunobva data/Moyo Int. 2017; 12(1): e1-e7.)

Ukobvu hwemadziro emadziro egonzo

[Cherechedza] Iyo vascular "intima" uye "media" ndiyo inonyanya kukosha nzvimbo dzeatherosclerosis.Iyo iri padyo neukobvu hwavo kune iyo yetsinga pasi pechikafu chekudya, hutano hwetsinga dzeropa huchava.(Kudhirowa/Wu Tingyao, kunobva data/Moyo Int. 2017; 12(1): e1-e7.)

Kudzivirirwa kweGanoderma lucidumpolysaccharide peptides pahutano hwemwoyo inogona kunge isina kunyatsoratidzwa muzviratidzo zvinooneka.

Ongororo dziri pamusoro apa dzinoratidza kuti kunyangwe chikonzero cheatherosclerosis (kudya kwemafuta akawandisa) chiripo, uye lipids yeropa ichiri isina kujairika,Ganoderma lucidumpolysaccharide peptides inogona kuchengetedza tsinga dzeropa mune zvine hutano mamiriro kuburikidza nekatatu mhedzisiro ye-anti-oxidation, anti-inflammation uye nekuvandudza mukana wekugadzirisa akakuvadzwa tsinga madziro.Uye mhedzisiro yeGanoderma lucidumpolysaccharide peptides inoenderana nemwero wayo.

Nekuti boka rekutsvagisa rakambosimbisa kuburikidza nezvidzidzo zvekiriniki kuti kushandiswa kweizviGanoderma lucidumpolysaccharide peptides kugadzirira adjuvant kurapwa kwevarwere vane angina pectoris anogona zvikuru kunatsiridza kuzvimba, oxidative kukuvara, shuga muropa, uye ropa lipids mumuviri, nokudaro kuderedza kuwanda uye kuoma kweangina pectoris.Naizvozvo, kugona kwekiriniki yekushandisa kweGanoderma lucidumpolysaccharide peptides zvechokwadi akakodzera zvatinotarisira.

Zvidzidzo zvakawanda munguva yakapfuura zvakashandisa "kudzikisa lipids yeropa kune yakajairika" sechiratidzo chekushanda kweGanoderma lucidummukudzivirira hurongwa hwemwoyo.Nekudaro, tsvagiridzo kubva kuIndonesia inotiudza kuti kunyangwe kana lipids yeropa isati yadzokera kune yakajairika, kana kunyangwe angina pectoris ichiri kuitika, isu hatifanirwe kuodzwa mwoyo.Ganoderma lucidumnokuti rinoshanda, asi hamugoni kuona mashandiro aro nemeso enyu.Chero bedzi iyo inodyiwa kazhinji uye kwenguva yakareba, kuchengetedzwa kweGanoderma lucidumpa cardiovascular system ichaenderera mberi.

[Data Source] Wihastuti TA, et al.Iyo inhibitory mhedzisiro yepolysaccharide peptides (PsP) yeGanoderma lucidum kurwisa atherosclerosis mumakonzo ane dyslipidemia.Moyo Int.2017;12(1): e1-e7.

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Nezve munyori/ Ms. Wu Tingyao
Wu Tingyao anga achizivisa nezvekutanga-ruoko ruzivo rweGanoderma kubvira 1999. Ndiye munyori weKuporesa neGanoderma(yakabudiswa muThe People's Medical Publishing House muna Kubvumbi 2017).
 
★ Chinyorwa ichi chakatsikiswa pasi pemvumo yakasarudzika yemunyori.★ Mabhuku ari pamusoro haagone kutsikiswa, kutorwa kana kushandiswa nedzimwe nzira pasina mvumo yemunyori.★ Nekutyorwa kwechirevo chiri pamusoro, munyori achatevera mabasa akakodzera emutemo.★ Manyoro ekutanga echinyorwa ichi akanyorwa neChinese naWu Tingyao uye akashandurirwa muchiRungu naAlfred Liu.Kana paine mutsauko pakati peshanduro (yeChirungu) neyekutanga (Chinese), iyo yekutanga Chinese ichakunda.Kana vaverengi vaine mibvunzo, tapota taura nemunyori wemabviro, Ms. Wu Tingyao.