Ku ya 12 Mata 2017 / Kaminuza ya Brawijaya / Umutima Mpuzamahanga

Inyandiko / Wu Tingyao

Indyo ndende ya cholesterol irashobora kumara byoroshye lipide yamaraso idasanzwe, kandi lipide yamaraso idasanzwe irashobora gutera aterosklerose.Ariko, nibaGanoderma lucidumpolysaccharide iraterwa, nubwo lipide yamaraso ikiri idasanzwe, ibyago byo kuba aterosklerozose birashobora kugabanuka.

“Heart International” yasohoye raporo yaturutse muri kaminuza ya Brawijaya muri Indoneziya mu 2017, ibigaragazaGanoderma lucidumpolysaccharide peptide (protein ikungahaye β-D-glucan yakuwe muriGanoderma lucidum) bigira ingaruka zo gukingira.

Ingaruka nyinshi zirwanya aterosklerose

Abashakashatsi bagaburiye imbeba ibyokurya bya cholesterol nyinshi mu byumweru 12.Amatsinda atatu yimbeba yagaburiwe icyarimwe hamwe na dosiye nkeya, iringaniye kandi ndende (50, 150, 300 mg / kg) yaGanoderma lucidumpolyisikaride peptide (PsP) itegura, irimo 20%Ganoderma lucidumpolysaccharide peptide, mubyumweru 4 byanyuma byubushakashatsi.

Nyuma yubushakashatsi, ubuzima bwimitsi yamaraso yimbeba bwasesenguwe hifashishijwe ibipimo bine, kandi ibisubizo bikurikira byabonetse kubyerekeranye nimbeba zariyeGanoderma lucidumpeptide ya polysaccharide:

1. Ubwinshi bwa radicals yubuntu H2O2 muri serumu iri hasi cyane - cholesterol ya lipoprotein nkeya (LDL-C) yegeranijwe mu rukuta rwamaraso ihindurwamo okiside na radicals yubuntu, iyi ikaba ari intambwe yambere yo gushiraho aterosklerose.Iyo radicals yubusa igabanutse, amahirwe ya atherosklerozose aragabanuka.

2. Ururenda rwa IL-10, cytokine irwanya inflammatory, rugabanuka - bivuze ko urugero rwo gutwika rworoheje, bityo rero ntihakenewe IL-10 nyinshi kugirango irwanye umuriro.

3. Umubare wa "endoteliyale progenitor selile" ushobora gukoreshwa mugusana inkuta zamaraso yangiritse wiyongereye - selile endoteliyale progenitor izenguruka umubiri wose hamwe namaraso irashobora gusana inkuta zamaraso yangijwe na okiside no gutwikwa.Kubwibyo, kwiyongera kwingirabuzimafatizo ya endoteliyale byerekana ko amahirwe yo gusana urukuta rwamaraso yangiritse yiyongereye, kandi amahirwe yo gukomeza guhinduka aterosklerose aragabanuka.

4. Ubunini bwurukuta rwimbere rwa aorta (intima nibitangazamakuru) byegeranye nibisanzwe - igice cyambukiranya imiyoboro y'amaraso gishobora kugabanywamo ibice bitatu uhereye imbere kugeza hanze: urukuta rw'umuyoboro w'amaraso uhuye hamwe n'amaraso yiswe intima, igizwe na selile endothelia;urwego rwagati rugizwe n'imitsi yoroshye yitwa itangazamakuru.Izi nzego zombi zingirangingo zamaraso nigice cyingenzi cyindwara ya atherosclerose.Kubwibyo, iyo umubyimba wibice byombi wegereye ibisanzwe, bivuze ko imiyoboro imeze neza.

Kwishyira ukizana kwa radical muri serumu yimbeba

[Icyitonderwa] H2O2 ni ubwoko bwubusa.Kugabanuka kwinshi kwayo, ntibishoboka ko habaho aterosklerose.(Igishushanyo / Wu Tingyao, isoko yamakuru / Umutima Int. 2017; 12 (1): e1-e7.)

Ubwinshi bwa anti-inflammatory cytokine muri serumu yimbeba

[Icyitonderwa] Iyo anti-inflammatory IL-10 yibanze muri serumu itari hejuru cyane, bivuze ko gutwika urukuta rw'imitsi y'amaraso bidashobora kuba bikomeye, kandi ibyago byo kurwara aterosklerose nabyo bigabanuka.(Igishushanyo / Wu Tingyao, isoko yamakuru / Umutima Int. 2017; 12 (1): e1-e7.)

Umubare w'ingirabuzimafatizo za endoteliyale mu maraso y'imbeba

[Icyitonderwa] Ingirabuzimafatizo ya endoteliyale irashobora gusana inkuta zamaraso yangiritse.Iyo umubare wabo wiyongereye, bivuze ko ibyago bya aterosklerose bigabanuka cyangwa bishobora gutinda.(Igishushanyo / Wu Tingyao, isoko yamakuru / Umutima Int. 2017; 12 (1): e1-e7.)

Ubunini bwurukuta rwa arterial yimbeba

[Icyitonderwa] Imitsi "intima" n "" itangazamakuru "nigice cyingenzi cyindwara ya aterosklerose.Iyo umubyimba wegereje cyane ni iy'imitsi iva mu ndyo isanzwe, imiyoboro y'amaraso izaba myiza.(Igishushanyo / Wu Tingyao, isoko yamakuru / Umutima Int. 2017; 12 (1): e1-e7.)

KurindaGanoderma lucidumpolysaccharide peptide kuri sisitemu yumutima nimiyoboro y'amaraso ntishobora kugaragara neza mubipimo bigaragara.

Ubushakashatsi bwavuzwe haruguru bwerekana ko nubwo igitera aterosklerose (indyo yuzuye amavuta) ikiriho, kandi lipide yamaraso iracyari idasanzwe,Ganoderma lucidumpeptide ya polysaccharide irashobora gutuma imiyoboro yamaraso itwara ubuzima bwiza ugereranije ningaruka eshatu zo kurwanya okiside, kurwanya inflammatory no kunoza amahirwe yo gusana inkuta zamaraso yangiritse.Ingaruka zaGanoderma lucidumpolysaccharide peptide iringaniza na dosiye yayo.

Kuberako itsinda ryubushakashatsi ryemeje mbere binyuze mubushakashatsi bwamavuriro ko ikoreshwa ryibiGanoderma lucidumpolysaccharide peptide itegura uburyo bwo kuvura abarwayi barwaye pectoris irashobora guteza imbere cyane umuriro, kwangirika kwa okiside, isukari yamaraso, hamwe na lipide yamaraso mumubiri, bityo bikagabanya inshuro nuburemere bwa pectoris ya angina.Kubwibyo, ivuriro rishobora gukoreshwa ryaGanoderma lucidumpolysaccharide peptide rwose irakwiriye ibyo dutegereje.

Ubushakashatsi bwinshi bwashize bwakoresheje "kugabanya lipide yamaraso mubisanzwe" nkikimenyetso cyerekana imikorere yaGanoderma lucidummukurinda sisitemu yumutima.Nyamara, ubushakashatsi bwakorewe muri Indoneziya butubwira ko niyo lipide yamaraso itasubiye mubisanzwe, cyangwa niyo pectoris ya angina ikibaho, ntitugomba gutenguhaGanoderma lucidumkuberako yagiye ikora, ariko ntushobora kubona ingaruka zayo n'amaso yawe.Igihe cyose kiribwa kenshi kandi igihe kinini, kurindaGanoderma lucidumkuri sisitemu yumutima nimiyoboro izakomeza.

[Inkomoko yamakuru] Wihastuti TA, nibindi.Ingaruka zo kubuza peptide ya polysaccharide (PsP) ya Ganoderma lucidum kurwanya aterosklerose mu mbeba hamwe na dyslipidemiya.Umutima Int.2017;12 (1): e1-e7.

IHEREZO

Ibyerekeye umwanditsi / Madamu Wu Tingyao
Wu Tingyao yagiye atanga amakuru ku makuru ya Ganoderma kuva mu 1999. Ni umwanditsi waGukiza hamwe na Ganoderma(byasohotse mu gitabo cy’ubuvuzi cy’abaturage muri Mata 2017).
 
★ Iyi ngingo yasohowe uruhushya rwihariye rwumwanditsi.Works Ibikorwa byavuzwe haruguru ntibishobora gusubirwamo, gucibwa cyangwa gukoreshwa mubundi buryo utabiherewe uburenganzira n'umwanditsi.★ Kurenga ku magambo yavuzwe haruguru, umwanditsi azakurikirana inshingano zemewe n'amategeko.Text Umwandiko wumwimerere wiyi ngingo wanditswe mu gishinwa na Wu Tingyao uhindurwa mu cyongereza na Alfred Liu.Niba hari itandukaniro riri hagati yubuhinduzi (icyongereza) numwimerere (igishinwa), igishinwa cyumwimerere kizatsinda.Niba abasomyi bafite ikibazo, nyamuneka hamagara umwanditsi wambere, Madamu Wu Tingyao.