ʻApelila 12, 2017 / Kulanui o Brawijaya / Heart International

Text/ Wu Tingyao

Hiki ke alakaʻi maʻalahi ka ʻai ʻana i ka cholesterol kiʻekiʻe i ka wā lōʻihi i nā lipids koko ʻino, a hiki i nā lipids koko ʻano lōʻihi ke alakaʻi i ke atherosclerosis.Eia naʻe, ināʻO Ganoderma lucidumHoʻopili ʻia ka polysaccharides, ʻoiai inā he ʻano like ʻole nā ​​lipids koko, hiki ke hoʻemi ʻia ka pilikia o ka atherosclerosis.

Ua paʻi ʻo "Heart International" i kahi hōʻike mai ke Kulanui o Brawijaya ma Indonesia ma 2017, e hōʻike ana i kēlāʻO Ganoderma lucidumpolysaccharide peptides (waiwai i ka protein β-D-glucan i lawe ʻia maiʻO Ganoderma lucidum) loaʻa kēia hopena pale.

ʻO nā hopena he nui i ka atherosclerosis

Ua hānai nā mea noiʻi i nā ʻiole me kahi meaʻai kiʻekiʻe-cholesterol no 12 pule.ʻEkolu mau pūʻulu ʻiole i hānai ʻia i ka manawa like me nā haʻahaʻa haʻahaʻa, waena a kiʻekiʻe (50, 150, 300 mg/kg) oʻO Ganoderma lucidumʻO ka hoʻomākaukau ʻana i nā polysaccharide peptides (PsP), nona ka 20%ʻO Ganoderma lucidumpolysaccharide peptides, i nā pule 4 hope loa o ka hoʻokolohua.

Ma hope o ka hoʻokolohua, ua ʻike ʻia ke olakino o nā kīʻaha koko o nā ʻiole ma o nā hōʻailona ʻehā, a ua ʻike ʻia nā hopena e pili ana i nā ʻiole i ʻai.ʻO Ganoderma lucidumʻO nā peptides polysaccharide:

1. He haʻahaʻa loa ka manaʻo o nā radical manuahi H2O2 i loko o ka serum - ʻo ka lipoprotein cholesterol haʻahaʻa haʻahaʻa (LDL-C) i hōʻiliʻili ʻia i loko o ka paia o ka moku koko e oxidized e nā radical manuahi, ʻo ia ka hana mua i ka hoʻokumu ʻana o atherosclerosis.I ka emi ʻana o nā radical manuahi, emi maoli ka manawa o ka atherosclerosis.

2. ʻO ka huna ʻana o IL-10, he cytokine anti-inflammatory, ua hoʻemi ʻia - ʻo ia ka mea maʻalahi ke degere o ka ʻāʻī, no laila ʻaʻohe pono o ka IL-10 e hakakā i ka ʻeha.

3. Ua hoʻonui ʻia ka nui o nā "endothelial progenitor cell" i hiki ke hoʻohana ʻia no ka hoʻoponopono ʻana i nā paia kīʻaha koko i hoʻopōʻino ʻia - endothelial progenitor cell e kaapuni ana i ke kino me ke koko hiki ke hoʻoponopono i nā paia kīʻaha koko i hōʻino ʻia e ka oxidation a me ka mumū.No laila, ʻo ka hoʻonui ʻana o nā cell progenitor endothelial e hōʻike ana e hoʻonui ʻia ka hiki ke hoʻoponopono i ka paia o ke kīʻaha koko i hōʻino ʻia, a ua emi iki ka manawa e ulu hou ai i ke atherosclerosis.

4. ʻO ka mānoanoa o ka paia o loko o ke aorta (intima a me ka media) kokoke i ka mea maʻamau - hiki ke hoʻokaʻawale ʻia ka ʻāpana o ka moku arterial i ʻekolu mau papa mai loko a i waho: ka paia o ke kīʻaha koko i pili. me ke kahe o ke koko i kapa ʻia ʻo ka intima, ka mea i hoʻokumu ʻia me nā ʻāpana endothelial;kapa ʻia ka papa waena i haku ʻia me ka ʻiʻo maʻemaʻe.ʻO kēia mau ʻāpana ʻelua o nā ʻiʻo vascular nā wahi lesion nui loa o ka atherosclerosis.No laila, ke kokoke loa ka mānoanoa o nā papa ʻelua i ka mea maʻamau, ʻo ia ke ʻano o ke ʻano o ke aʻa i kahi kūlana olakino.

ʻO ka manaʻo o ka radical manuahi i ka serum iole

[E hoʻomaopopo] ʻO H2O2 kekahi ʻano o ka radical manuahi.ʻO ka haʻahaʻa haʻahaʻa, ʻoi aku ka liʻiliʻi o ka hana ʻana i ka atherosclerosis.(Ke kaha kiʻi/Wu Tingyao, kumu ʻikepili/Heart Int. 2017; 12(1): e1-e7.)

ʻO ka manaʻo o ka cytokine anti-inflammatory i ka serum iole

[Note] I ka wā ʻaʻole kiʻekiʻe loa ka ʻike anti-inflammatory IL-10 i loko o ka serum, e hōʻike ana ʻaʻole i koʻikoʻi ka mumū o ka paia o ka moku koko, a ua hoʻemi ʻia ka pilikia o ka atherosclerosis.(Ke kaha kiʻi/Wu Tingyao, kumu ʻikepili/Heart Int. 2017; 12(1): e1-e7.)

ʻO ka helu o nā pūnaewele progenitor endothelial i ke koko ʻiole

[Note] Hiki i nā pūnaewele progenitor Endothelial ke hoʻoponopono i nā paia moku koko i poino.Ke piʻi aʻe ko lākou helu, ʻo ia ka mea e hōʻemi ʻia ka pilikia o ka atherosclerosis a hiki ke lohi.(Ke kaha kiʻi/Wu Tingyao, kumu ʻikepili/Heart Int. 2017; 12(1): e1-e7.)

ʻO ka mānoanoa o ka pā aʻe o ka ʻiole

[Note] ʻO ka "intima" vascular a me "media" nā wahi lesion nui loa o ka atherosclerosis.ʻOi aku ka ʻoi aku o ka mānoanoa o nā aʻa ma lalo o ka meaʻai maʻamau, ʻoi aku ka maikaʻi o nā kīʻaha koko.(Ke kaha kiʻi/Wu Tingyao, kumu ʻikepili/Heart Int. 2017; 12(1): e1-e7.)

Ka palekana oʻO Ganoderma lucidumʻAʻole hiki ke ʻike piha ʻia nā peptides polysaccharide ma ka ʻōnaehana cardiovascular i nā hōʻailona ʻike ʻia.

Hōʻike nā hoʻokolohua ma luna aʻe ʻoiai ke mau nei ke kumu o ka atherosclerosis (ʻai momona momona), a ʻaʻole mau nā lipids koko,ʻO Ganoderma lucidumHiki i nā polysaccharide peptides ke mālama i nā kīʻaha koko i loko o kahi kūlana olakino ma o nā hopena triple o ka anti-oxidation, anti-inflammation a me ka hoʻomaikaʻi ʻana i ka manawa e hoʻoponopono ai i nā paia moku koko i poino.A me ka hopena oʻO Ganoderma lucidumHoʻohālikelike ʻia nā peptides polysaccharide i kāna ʻano.

No ka mea, ua hōʻoia mua ka hui noiʻi ma o nā noiʻi lapaʻau i ka hoʻohana ʻana i kēiaʻO Ganoderma lucidumʻO ka hoʻomākaukau ʻana o ka polysaccharide peptides no ka mālama ʻana i nā maʻi me ka angina pectoris hiki ke hoʻomaikaʻi nui i ka mumū, ka pōʻino oxidative, ke koko koko, a me nā lipids koko i loko o ke kino, a laila e hōʻemi i ka pinepine a me ka paʻakikī o ka angina pectoris.No laila, ʻo ka hiki ke noi lapaʻau oʻO Ganoderma lucidumʻO nā peptides polysaccharide he kūpono i kā mākou mau manaʻo.

Nui nā haʻawina i ka wā ma mua i hoʻohana i ka "hoʻohaʻahaʻa i ka lipids koko i ka maʻamau" ma ke ʻano he hōʻailona kikoʻī o ka pono oʻO Ganoderma lucidumi ka pale ʻana i ka ʻōnaehana cardiovascular.Eia nō naʻe, haʻi mai ka noiʻi mai Indonesia iā mākou inā ʻaʻole i hoʻi hou nā lipids koko i ka maʻamau, a i ʻole inā e kū mau ana ka angina pectoris, ʻaʻole pono mākou e hoka.ʻO Ganoderma lucidumno ka mea, ua hana ia, akā ʻaʻole hiki iā ʻoe ke ʻike i kona hopena me kou mau maka ponoʻī.I ka wā e ʻai pinepine ʻia a no ka manawa lōʻihi, ka pale oʻO Ganoderma lucidumma ka ʻōnaehana cardiovascular e hoʻomau.

[Kumuʻikepili] Wihastuti TA, et al.Nā hopena pale o nā polysaccharide peptides (PsP) o Ganoderma lucidum e kū'ē i ke atherosclerosis i nāʻiole me ka dyslipidemia.Heart Int.2017;12(1): e1-e7.

HOPE

No ka mea kākau/ Ms. Wu Tingyao
Ua hōʻike ʻo Wu Tingyao i ka ʻike Ganoderma lima mua mai 1999. ʻO ia ka mea kākau oHoola me Ganoderma(i paʻi ʻia ma The People's Medical Publishing House ma ʻApelila 2017).
 
★ Ua paʻi ʻia kēia ʻatikala ma lalo o ka mana kūʻokoʻa o ka mea kākau.★ ʻAʻole hiki ke paʻi hou ʻia nā hana i luna, ʻokiʻoki a hoʻohana ʻia ma nā ʻano ʻē aʻe me ka ʻole o ka ʻae ʻia e ka mea kākau.★ No ka uhaki ʻana i ka ʻōlelo ma luna, e ʻimi ka mea kākau i nā kuleana pili kānāwai.★ Ua kākau ʻia ka kikokikona kumu o kēia ʻatikala ma ka ʻōlelo Pākē e Wu Tingyao a unuhi ʻia i ka ʻōlelo Pelekania e Alfred Liu.Inā loaʻa kekahi ʻokoʻa ma waena o ka unuhi (English) a me ka unuhi mua (Pake), e lanakila ka Pākē mua.Inā he nīnau ka poʻe heluhelu, e ʻoluʻolu e kelepona i ka mea kākau kumu, ʻo Ms. Wu Tingyao.