Na 2018, 9th International Conference on Mushroom Biology and Mushroom Products mere na Shanghai.Dr. Hua Fan sitere na Mahadum Free nke Berlin, Germany, nyere akụkọ na nzukọ ahụ wee kesaa nsonaazụ nyocha nke ụlọ nyocha ya na ndị otu Jinsong Zhang, Institute of Food Fungi, Shanghai Academy of Agricultural Sciences mere.Mkparịta ụka ka otu otuGanoderma lucidumpolysaccharide na-achịkwa usoro mgbochi na mgbochi ọrịa kansa yana nyocha etu otuGanoderma lucidumtriterpene na-egbochi uto nke mkpụrụ ndụ kansa na-enye ikike ahụike nkeGanoderma lucidumna atụmanya nke ọgwụ ọhụrụ.

Ederede/ Wu Tingyao

Dị ka onye ọbịa nke nzukọ ahụ, Jinsong Zhang, onye nduzi nke Institute of Food Fungi, Shanghai Academy of Agricultural Sciences, nyere Dr. Hua Fan akwụkwọ.Abụọ ndị nwere mmekọrịta onye nkuzi na ụmụ akwụkwọ bụ ndị ọkwọ ụgbọ ala dị mkpa nke na-eweta ọgwụ ọdịnala Chinese Ganoderma banye n'ụlọ nzukọ sayensị Europe.(Foto/Wu Tingyao)

Hua Fan, onye amuru na China ma kụọGanoderma lucidumna 1960 na 70s, bụ otu n'ime ndị ọkà mmụta sayensị China ole na ole a ma ama bụ ndị gara Germany ịga mụọ mba ọzọ n'oge mbụ.Na mmalite 1990s ka emebere usoro nyocha nke immunological na mgbochi tumor na Mahadum Free nke Berlin dị na Germany, ọ malitere imekọ ihe na Institute of Food Fungi, Shanghai Academy of Agricultural Sciences iji nyochaa akụkụ bioactive nke ihe ọkụkụ.Ganoderma lucidumna ọgwụ fungi ndị ọzọ.

Nwa akwụkwọ gụsịrị akwụkwọ bụ onye gara Germany maka mgbanwe na nnọchite nke Institute of Food Fungi, Shanghai Academy of Agricultural Sciences bụ onye isi na-ahụ maka Mgbakọ Mba Nile nke 9th na Mushroom Biology and Mushroom Products, Jinsong Zhang, onye isi ụlọ ọrụ Institute of Fungi Dible. ;Hua Fan bụ onye nlekọta doctoral nyeere Jinsong Zhang aka inweta nzere MD ya na Mahadum Free nke Berlin, Germany.

Mgbe Jinsong Zhang laghachiri na China, ọ gara n'ihu na-arụkọ ọrụ na ụlọ nyocha Hua Fan.Ndị otu Jinsong Zhang na Institute of Food Fungi nyere polysaccharides na triterpenes na akụkọ dị n'elu.Ihe fọrọ nke nta ka ọ bụrụ afọ iri abụọ nke imekọ ihe ọnụ n'etiti akụkụ abụọ ahụ bụ ihe dị oke mkpa maka iwebata Ganoderma n'ime ụlọ nyocha nke Europe na nkwalite nyocha zuru ụwa ọnụ na Ganoderma.

Polysaccharides nwere akụkụ dị iche iche nwere ọrụ mgbochi dị iche iche.

Ndị otu ahụ kewapụrụ ma sachaa macromolecular polysaccharide GLIS nwere 8-9% protein sitere na ahụ mfri nkeGanoderma lucidum.Nnwale cell gosipụtara na GLIS nwere ike ịgbalite usoro ahụ ji alụso ọrịa ọgụ site na mgbochi cellular (ịmalite macrophages) na mgbochi ihu ọchị (ịmalite lymphocytes gụnyere mkpụrụ ndụ B).

N'ezie, ịgbanye GLIS na dose nke 100μg n'ime òké ọ bụla ejirila S180 sarcoma sel ga-amụba ọnụ ọgụgụ nke mkpụrụ ndụ splin (nwere lymphocytes) ihe fọrọ nke nta ka ọ bụrụ otu ụzọ n'ụzọ atọ ma gbochie uto tumor (ọnụego mgbochi ruru 60 ~ 70%).Nke a pụtara naGanoderma lucidumpolysaccharide GLIS nwere ikike ịkwalite ikike sistemu ahụ ji alụso etuto ahụ ọgụ.

N'ụzọ na-akpali mmasị, polysaccharide ọzọ dị ọcha, GLPss58, nke dịpụrụ adịpụ naGanoderma lucidumahụ na-amị mkpụrụ, bụ sulfated na enweghị protein, ọ bụghị naanị na ọ naghị akwalite mgbochi dị ka gliS kamakwa ọ nwere ike igbochi mmụba na ọrụ nke macrophages na lymphocytes, belata mmepụta nke cytokines na-egbuke egbuke, ma gbochie lymphocytes n'ime ọbara ịkwaga n'ime ọkụ. Anụ ahụ… Usoro ya dị iche iche na-ebelata ike nke nzaghachi mgbochi ahụ.Mmetụta a dabara adaba maka mkpa ahụike nke ndị ọrịa nwere oke ọnya na-adịghị ala ala (dịka lupus erythematosus na ọrịa autoimmune ndị ọzọ).

Usoro mgbochi ọrịa kansa nke triterpenoids dị iche na nke polysaccharides.

Na mgbakwunye, ndị otu Hua Fan tụlekwara ọrụ anticancer nke ogige triterpene asatọ n'ime ahụ nke mkpụrụ osisi.Ganoderma lucidum.Nsonaazụ gosiri na abụọ n'ime triterpenes ndị a nwere mmetụta antiproliferative na pro-apoptotic na mkpụrụ ndụ cancer ara mmadụ, mkpụrụ ndụ cancer colorectal mmadụ na mkpụrụ ndụ melanoma na-adịghị mma.

Na nyocha ọzọ nke usoro nke triterpenes abụọ a na-akwalite apoptosis nke mkpụrụ ndụ kansa, ndị nchọpụta ahụ chọpụtara na ha "na-amanye" mkpụrụ ndụ cancer ka ha bibie onwe ha site na "ibelata ikike nke mitochondria" na "ịbawanye nrụgide oxidative nke mitochondria" .Nke a bụ kpamkpam dị iche iche si ọrụ nkeGanoderma lucidumpolysaccharide GLIS nke "na-apụtaghị ìhè" na-egbochi etuto ahụ site na usoro ahụ ji alụso ọrịa ọgụ.

Enwere ike iji polysaccharides ma ọ bụ triterpenes mee ihe otu ma ọ bụ ngwakọta.

Hua Fan mere ka anyị ghọta site na usoro nyocha German siri ike nke ihe dị iche iche na-arụ ọrụ dị na yaGanoderma lucidumenwere ike "jikọta" iji mepụta uru ahụike nke ịgbatị ndụ ma ọ bụ nwee ike "itinye ya iche" iji nye mmetụta ọgwụgwọ kpọmkwem maka ọrịa ndị dị ugbu a.

Ọ ga-ekwe omume ịme polysaccharides na-arụ ọrụ na triterpenes na-arụ ọrụ na nnwale ahụ n'ime ọgwụ ọgwụ n'ọdịnihu?"Ya mere, lee ọgbọ ndị na-eto eto!"Hua Fan lere anya na Jinsong Zhang, onye ewepụtalarị otu ndị nyocha siri ike.

E si na ya wepụta akụkọ aKedu isiokwu Ganoderma dị mkpa ka a tụlere na ogbako ero ero kacha mkpa na 2018?-Tọ 9th International Conference on Mushroom Biology and Mushroom Products(Nkebi nke 2).

Dr. Hua Fan sitere na Mahadum Free nke Berlin, Germany, nyere ihe ngosi na "Ịchọgharị ike nlekọta ahụike nke Ganoderma" na 9th International Conference on Mushroom Biology and Mushroom Products.(Foto/Wu Tingyao)

N'ikpeazụ

Banyere onye odee/ Oriakụ Wu Tingyao
Wu Tingyao na-akọ akụkọ mbụGanoderma lucidumozi kemgbe 1999. O bu odeeỌgwụgwọ na Ganoderma(nke e bipụtara na The People's Medical Publishing House na Eprel 2017).
 
★ A na-ebipụta akụkọ a n'okpuru ikike nke onye edemede ★ Ọrụ ndị a dị n'elu enweghị ike imepụtaghachi, wepụ ma ọ bụ jiri ya mee ihe n'ụzọ ndị ọzọ na-enweghị ikike nke onye edemede ★ imebi okwu a dị n'elu, onye edemede ga-agbaso ọrụ iwu metụtara ya ★ The mbụ Wu Tingyao dere ederede akụkọ a n'asụsụ Chinese ma Alfred Liu sụgharịrị ya na Bekee.Ọ bụrụ na enwere nghọtahie n'etiti ntụgharị asụsụ (Bekee) na nke izizi (Chinese), Chinese izizi ga-emeri.Ọ bụrụ na ndị na-agụ akwụkwọ nwere ajụjụ ọ bụla, biko kpọtụrụ onye edemede mbụ bụ Oriakụ Wu Tingyao.