A shekarar 2018, an gudanar da taron kasa da kasa karo na 9 kan halittun namomin kaza da naman kaza a birnin Shanghai.Dokta Hua Fan daga jami'ar Free University of Berlin ta kasar Jamus, ta ba da rahoto a wajen taron, inda ta bayyana sakamakon binciken da dakin gwaje-gwajenta da kungiyar Jinsong Zhang ta yi tare da cibiyar nazarin fungi mai cin abinci ta kwalejin kimiyyar aikin gona ta Shanghai.Tattaunawar yadda guda dayaGanoderma lucidumpolysaccharide yana tsara hanyoyin rigakafi da rigakafin ciwon daji da kuma nazarin yadda guda ɗayaGanoderma lucidumtriterpene yana hana haɓakar ƙwayoyin cutar kansa suna ba da damar likita naGanoderma lucidumda kuma fatan sabbin kwayoyi.

Rubutu/ Wu Tingyao

A matsayin mai masaukin bakin taron, darektan cibiyar kula da fungi mai cin abinci na kwalejin kimiyyar aikin gona ta Shanghai Jinsong Zhang, ya ba da takardar shaida ga Dr. Hua Fan.Su biyun da ke da alakar malamai da dalibai su ne muhimman ababen da ke kawo maganin gargajiya na kasar Sin Ganoderma cikin zauren kimiyyar Turai.(Hotuna/Wu Tingyao)

Hua Fan, wacce aka haifa a China kuma aka shukaGanoderma luciduma shekarun 1960 da 70s, ya kasance daya daga cikin fitattun masana kimiyyar kasar Sin da suka je Jamus don yin karatu a kasashen waje a farkon zamanin.A farkon shekarun 1990 bayan da aka kafa dandalin gwajin rigakafi da rigakafin ciwon daji a jami'ar Free University of Berlin da ke Jamus, ta fara hada kai da Cibiyar Nazarin Fungi mai ci, Kwalejin Kimiyyar Aikin Gona ta Shanghai don gano abubuwan da suka shafi kwayoyin halitta.Ganoderma lucidumda sauran magungunan fungi.

Dalibin da ya kammala karatun digirin da ya je Jamus don yin musanya a madadin Cibiyar Nazarin Fungi mai cin abinci, Kwalejin Kimiyyar Aikin Noma ta Shanghai ita ce babban jami'in da ke jagorantar taron kasa da kasa karo na 9 kan halittun namomin kaza da namomin kaza, Jinsong Zhang, darektan cibiyar kula da fungi mai ci. ;Hua Fan ita ce babban mai kula da digiri na uku wanda ya taimaka Jinsong Zhang ya sami digirinsa na MD daga Jami'ar Free University of Berlin, Jamus.

Bayan da Jinsong Zhang ya koma kasar Sin, ya ci gaba da yin hadin gwiwa da dakin gwaje-gwajen Hua Fan.Tawagar Jinsong Zhang ta Cibiyar Kula da Fungi ce ta samar da polysaccharides da triterpenes a cikin rahoton da ke sama.Kusan shekaru 20 na hadin gwiwa tsakanin bangarorin biyu na da matukar muhimmanci ga shigar da Ganoderma a cikin dakin bincike na Turai da kuma inganta binciken duniya kan Ganoderma.

Polysaccharides tare da sassa daban-daban suna da ayyukan rigakafi daban-daban.

Ƙungiyar ta ware kuma ta tsarkake macromolecular polysaccharide GLIS mai dauke da furotin 8-9% daga jikin 'ya'yan itace.Ganoderma lucidum.Gwaje-gwajen tantanin halitta sun tabbatar da cewa GLIS na iya kunna tsarin rigakafi gaba ɗaya ta hanyar rigakafi ta salon salula (kunna macrophages) da rigakafi na jin daɗi (kunna lymphocytes ciki har da ƙwayoyin B).

A gaskiya ma, yin amfani da GLIS a kashi na 100μg a cikin kowane linzamin kwamfuta da aka riga aka yi wa alurar riga kafi tare da S180 sarcoma cell zai kara yawan adadin kwayoyin halitta (wanda ke dauke da lymphocytes) ta kusan kashi ɗaya bisa uku kuma ya hana ci gaban ƙwayar cuta (ƙididdigar hanawa ya kai 60 ~ 70%).Wannan yana nufin hakaGanoderma lucidumpolysaccharide GLIS yana da ikon haɓaka ƙarfin tsarin rigakafi don yaƙar ciwace-ciwace.

Abin sha'awa, wani polysaccharide mai tsabta, GLPss58, wanda ke keɓe dagaGanoderma lucidum'Ya'yan itãcen marmari, yana da sulfated kuma ba ya ƙunshi abubuwan gina jiki, ba wai kawai ba ya inganta rigakafi kamar gliS amma kuma zai iya hana yaduwar macrophages da lymphocytes, rage samar da cytokines mai kumburi, da hana lymphocytes a cikin jini daga ƙaura zuwa kumburi. kyallen takarda… Hanyoyinsa da yawa suna rage ƙarfin amsawar rigakafi.Wannan tasirin ya dace kawai don buƙatun likita na marasa lafiya tare da ƙumburi na yau da kullun (kamar lupus erythematosus da sauran cututtukan autoimmune).

Tsarin rigakafin ciwon daji na triterpenoid ya bambanta da na polysaccharides.

Bugu da kari, tawagar Hua Fan ta kuma kimanta ayyukan anticancer na mahadi guda takwas na triterpene guda takwas a cikin jikin 'ya'yan itace.Ganoderma lucidum.Sakamakon ya nuna cewa biyu daga cikin waɗannan triterpenes suna da tasiri mai mahimmanci na antiproliferative da pro-apoptotic akan kwayoyin cutar kansar nono, kwayoyin cutar kansar launi na mutum da kuma kwayoyin cutar melanoma.

A cikin ƙarin nazarin hanyoyin da waɗannan triterpenes guda biyu ke haɓaka apoptosis na ƙwayoyin cutar kansa, masu binciken sun gano cewa "kai tsaye" suna tilasta ƙwayoyin cutar kansa don lalata kansu ta hanyar "rage yuwuwar membrane na mitochondria" da "ƙara oxidative matsa lamba na mitochondria" .Wannan ya bambanta da aikinGanoderma lucidumpolysaccharide GLIS wanda "a kaikaice" ya hana ciwace-ciwace ta hanyar tsarin rigakafi.

Ana iya amfani da polysaccharides ko triterpenes guda ɗaya ko a hade.

Hua Fan ta sa mu fahimci ta hanyar ingantaccen tsarin bincike na Jamus wanda nau'ikan kayan aiki iri-iri a cikiGanoderma lucidumana iya "haɗe" don ƙirƙirar ƙimar lafiyar tsawaita rayuwa ko za'a iya "amfani daban" don samar da takamaiman tasirin warkewa ga cututtukan da ke akwai.

Shin zai yiwu a yi polysaccharides masu aiki da triterpenes masu aiki a cikin gwaji a cikin magungunan asibiti a nan gaba?"Sa'an nan ku dubi 'yan zamani!"Hua Fan ta dubi Jinsong Zhang, wanda ya riga ya kafa ƙungiyar bincike mai ƙarfi.

An ciro wannan labarin dagaWadanne mahimman batutuwan Ganoderma ne aka tattauna a cikin mafi mahimmancin taron naman kaza mai cin abinci a cikin 2018?- TTaron kasa da kasa karo na 9 akan Halittar Naman kaza da Kayayyakin Naman kaza(Kashi na 2).

Dokta Hua Fan daga Jami'ar Free University of Berlin, Jamus, ta ba da gabatarwa kan "Bincika Ƙimar Kiwon Lafiyar Ganoderma" a taron kasa da kasa karo na 9 kan Halittar Naman kaza da Kayayyakin namomin kaza.(Hotuna/Wu Tingyao)

KARSHE

Game da marubucin / Ms. Wu Tingyao
Wu Tingyao ya kasance yana bayar da rahoto da farkoGanoderma lucidumbayanai tun 1999. Ita ce marubucinWaraka tare da Ganoderma(an buga a The People's Medical Publishing House a Afrilu 2017).
 
★ An buga wannan labarin ne a ƙarƙashin izini na musamman na marubuci ★ Wadannan ayyukan da ke sama ba za a iya sake su ba, cirewa ko amfani da su ta wasu hanyoyi ba tare da izini daga marubucin ba. Wu Tingyao ne ya rubuta wannan labarin da Sinanci kuma Alfred Liu ya fassara shi zuwa Turanci.Idan akwai wani sabani tsakanin fassarar (Turanci) da na asali (China), asalin Sinanci zai yi nasara.Idan masu karatu suna da wasu tambayoyi, tuntuɓi marubuciyar asali, Ms. Wu Tingyao.