Ma 2018, ua mālama ʻia ka 9th International Conference on Mushroom Biology and Mushroom Products ma Shanghai.Ua hāʻawi ʻo Kauka Hua Fan mai ke Kulanui Kūʻokoʻa o Berlin, Kelemānia, i kahi hōʻike ma ka hālāwai a hōʻike i ka hopena o ka noiʻi i hana pū ʻia e kāna keʻena keʻena a me Jinsong Zhang's Team, Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences.ʻO ke kūkākūkā e pili ana i kahi hoʻokahiʻO Ganoderma lucidumHoʻoponopono ka polysaccharide i nā mīkini pale a anti-cancer a me ka nānā ʻana i ke ʻano o ka hoʻokahiʻO Ganoderma lucidumtriterpene keʻakeʻa i ka ulu ʻana o nā maʻi maʻi maʻi e hāʻawi i ka hiki ke olakino oʻO Ganoderma luciduma me ka manao o na laau hou.

Text/ Wu Tingyao

Ma keʻano he mea hoʻokipa o ka hālāwai, ua hāʻawiʻo Jinsong Zhang, ka luna o ka Institute of Edible Fungi, Shanghai Academy of Agricultural Science, i palapala hōʻoia iā Kauka Hua Fan.ʻO lāua ʻelua ka pilina kumu-haumāna nā mea hoʻokele koʻikoʻi o ka lawe ʻana mai i ka lāʻau lapaʻau Kina kuʻuna Ganoderma i loko o ka hale ʻepekema ʻEulopa.(Photography/Wu Tingyao)

ʻO Hua Fan, i hānau ʻia ma Kina a kanu ʻiaʻO Ganoderma lucidumi nā makahiki 1960 a me 70, ʻo ia kekahi o nā kānaka ʻepekema Kina koʻikoʻi i hele i Kelemānia e aʻo i nā ʻāina ʻē i nā lā mua.I nā makahiki 1990 mua ma hope o ka hoʻokumu ʻia ʻana o kahi kahua hoʻokolohua immunological a anti-tumor ma ke Kulanui Free o Berlin ma Kelemānia, ua hoʻomaka ʻo ia e hui pū me ka Institute of Edible Fungi, Shanghai Academy of Agricultural Science e ʻimi i nā mea bioactive oʻO Ganoderma luciduma me nā haʻi lāʻau lapaʻau ʻē aʻe.

ʻO ka haumāna puka i hele i Kelemānia no ka hoʻololi ʻana ma ka inoa o Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences ʻo ia ka mea nui i mālama i ka 9th International Conference on Mushroom Biology and Mushroom Products, Jinsong Zhang, ka luna o ka Institute of Edible Fungi ;ʻO Hua Fan ka luna kauka kauka nāna i kōkua iā Jinsong Zhang e loaʻa kāna kēkelē MD mai ke Kulanui Free o Berlin, Kelemānia.

Ma hope o ka hoʻi ʻana o Jinsong Zhang i Kina, ua hoʻomau ʻo ia i ka hana pū me ka hale hana ʻo Hua Fan.Ua hāʻawi ʻia nā polysaccharides a me triterpenes i ka hōʻike ma luna e ka hui o Jinsong Zhang ma Institute of Edible Fungi.ʻO ka aneane ʻelua mau makahiki o ka launa pū ʻana ma waena o nā ʻaoʻao ʻelua he mea koʻikoʻi nui no ka hoʻokomo ʻana o Ganoderma i loko o ka hale noiʻi ʻEulopa a me ka hoʻolaha ʻana i ka noiʻi honua ma Ganoderma.

ʻO nā polysaccharides me nā ʻano hana like ʻole he mau hana pale ʻokoʻa.

Ua hoʻokaʻawale a hoʻomaʻemaʻe ka hui i ka macromolecular polysaccharide GLIS i loaʻa ka 8-9% protein mai nā kino hua oʻO Ganoderma lucidum.Ua hōʻoia ʻia nā hoʻokolohua kelepona hiki iā GLIS ke hoʻāla i ka ʻōnaehana pale āpau ma o ka pale ʻana o ke kelepona (hoʻoulu ʻana i nā macrophages) a me ka pale ʻana i ka humoral (hoʻoulu ʻia o nā lymphocytes me nā pūnaʻi B).

ʻOiaʻiʻo, ʻo ka hoʻokomo ʻana i ka GLIS ma kahi ʻano o 100μg i kēlā me kēia ʻiole i hoʻopaʻa mua ʻia me ka S180 sarcoma cell e hoʻonui i ka nui o nā pūnaewele spleen (loaʻa nā lymphocytes) ma kahi kokoke i hoʻokahi hapakolu a kāohi i ka ulu ʻana o ka maʻi maʻi (hiki i ka 60 ~ 70%).ʻO ia hoʻiʻO Ganoderma lucidumHiki i ka polysaccharide GLIS ke hoʻoikaika i ka hiki o ka ʻōnaehana pale ke kaua i nā ʻōpū.

ʻO ka mea hoihoi, ʻo kekahi polysaccharide maʻemaʻe, ʻo GLPss58, i hoʻokaʻawale ʻia maiʻO Ganoderma lucidumʻO ke kino hua, he sulfated a ʻaʻohe mea protein, ʻaʻole wale e hoʻoikaika i ka pale ʻana e like me GLIS akā hiki ke kāohi i ka hoʻonui a me ka hana o nā macrophages a me nā lymphocytes, hoʻemi i ka hana ʻana o nā cytokine inflammatory, a pale i nā lymphocytes i loko o ke koko mai ka neʻe ʻana i ka mea maʻi. tissues… ʻO kāna mau hana he nui e hoʻemi i ka ikaika o ka pane ʻana o ke kino.He kūpono kēia hopena no nā pono lapaʻau o nā poʻe maʻi me ka ʻeha nui loa (e like me ka lupus erythematosus a me nā maʻi autoimmune ʻē aʻe).

ʻOkoʻa ka hana anti-cancer o triterpenoids mai ka polysaccharides.

Eia kekahi, ua loiloi pū ka hui o Hua Fan i ka hana anticancer o ʻewalu mau pūhui triterpene hoʻokahi i loko o ke kino hua oʻO Ganoderma lucidum.Ua hōʻike ʻia nā hopena he ʻelua o kēia mau triterpenes he hopena antiproliferative a me ka pro-apoptotic i nā maʻi maʻi maʻi umauma o ke kanaka, nā maʻi maʻi maʻi colorectal kanaka a me nā cell melanoma malignant.

I ka nānā hou ʻana i nā hana e hoʻolaha ai kēia mau triterpenes ʻelua i ka apoptosis o nā maʻi maʻi maʻi, ua ʻike nā mea noiʻi ua "pololei" lākou i nā cell cancer e luku iā lākou iho ma o ka "hoʻemi ʻana i ka hikiwawe o ka mitochondria" a me ka "hoʻonui ʻana i ke kaomi oxidative o mitochondria" .He ʻokoʻa loa kēia mai ke kuleana oʻO Ganoderma lucidumpolysaccharide GLIS ka mea "indirectly" inhibits tumors ma o ka immune system.

Hiki ke hoʻohana hoʻokahi a hui pū paha nā polysaccharides a i ʻole triterpenes.

Ua hoʻomaopopo ʻo Hua Fan iā mākou ma o ke ʻano noiʻi koʻikoʻi Kelemania i loaʻa i nā mea hana like ʻoleʻO Ganoderma lucidumhiki ke "hoʻohui" e hana i ka waiwai olakino o ka hoʻolōʻihi ʻana i ke ola a i ʻole hiki ke "pili ʻokoʻa" e hāʻawi i nā hopena curative kūikawā no nā maʻi e kū nei.

Hiki paha ke hana i nā polysaccharides ikaika a me nā triterpenes ikaika i ka hoʻokolohua i nā lāʻau lapaʻau i ka wā e hiki mai ana?"A laila e nānā i ka hanauna ʻōpio!"Ua nānā nui ʻo Hua Fan iā Jinsong Zhang, nāna i hoʻokumu i kahi hui noiʻi ikaika.

Wehe ʻia kēia ʻatikala maiHe aha nā kumuhana Ganoderma koʻikoʻi i kūkākūkā ʻia i ka hālāwai kūkā nui edible mushroom ma 2018?- The 9th International Conference on Mushroom Biology and Mushroom Products(Mahele 2).

Ua hāʻawi ʻo Kauka Hua Fan mai ke Kulanui Kūʻokoʻa o Berlin, Kelemānia, i kahi hōʻike ma ka "Exploring the Health Care Potential of Ganoderma" ma ka 9th International Conference on Mushroom Biology and Mushroom Products.(Photography/Wu Tingyao)

HOPE

No ka mea kākau/ Ms. Wu Tingyao
Ua hōʻike ʻo Wu Tingyao ma ka lima muaʻO Ganoderma lucidumʻike mai ka makahiki 1999. ʻO ia ke kumu oHoola me Ganoderma(i paʻi ʻia ma The People's Medical Publishing House ma ʻApelila 2017).
 
★ Ua paʻi ʻia kēia ʻatikala ma lalo o ka mana kūʻokoʻa o ka mea kākau ★ ʻAʻole hiki ke hana hou ʻia nā hana ma luna aʻe, ʻoki ʻia a hoʻohana ʻia ma nā ʻano ʻē aʻe me ka ʻole o ka ʻae ʻana o ka mea kākau ★ ʻAʻole i ʻae ʻia ka ʻōlelo ma luna, e hahai ka mea kākau i kāna mau kuleana pili i ke kānāwai ★ ʻO ke kumu kumu. Ua kākau ʻia nā kikokikona o kēia ʻatikala ma ka ʻōlelo Pākē e Wu Tingyao a unuhi ʻia i ka ʻōlelo Pelekania e Alfred Liu.Inā loaʻa kekahi ʻokoʻa ma waena o ka unuhi (English) a me ka unuhi mua (Pake), e lanakila ka Pākē mua.Inā he nīnau ka poʻe heluhelu, e ʻoluʻolu e kelepona i ka mea kākau kumu, ʻo Ms. Wu Tingyao.