A yau, mutane da yawa, lokacin zabarGanodermasamfurori, akai-akai tambaya, "Mene ne abun ciki na triterpene na samfurin ku?"Da alama cewa mafi girman abun ciki na triterpene, mafi kyawun samfurin.Duk da haka, wannan ba daidai ba ne.

A halin yanzu, hanyar da kamfanonin gida ke amfani da su don auna abun ciki naGanodermatriterpenes shine hanyar sinadarai.Wannan hanya tana da al'amurran da suka shafi musamman da manyan kurakurai.Sabili da haka, matakin abun ciki na triterpene ba zai iya wakiltar ingancin mai ba daidai ba 

A haƙiƙa, ingancin samfurin mai na spore yana ƙayyade ta hanyoyi daban-daban.chromatography na ruwa mai girma yana iya gano ainihin abun cikin "Ganoderic Acid A".Idan samfurin mai na spore zai iya nuna a sarari abun ciki na "Ganoderic Acid A", yana ba da garanti mafi girma na ingancin samfurin.Menene Ganoderic Acid A?Menene tasirinsa na musamman?Menene bambanci tsakaninsa da jimlar triterpenes?Yau, bari mu san shi.

Akwai nau'ikan nau'ikan sama da 300Ganodermatriterpene mahadi.Wadanne ne kuka saba dasu?

Na farko, yana da mahimmanci a san hakanGanodermamahadi na triterpene ba abu ɗaya ba ne, amma a maimakon haka koma zuwa abubuwan da ke cikiGanodermawanda ke da tsarin triterpene.Ya zuwa yau, an gano fiye da nau'ikan 300, an rarraba su a cikiGanoderma'ya'yan itace da kumaGanodermaspore foda.

Wadannan mahadi na triterpene za a iya rarraba su zuwa tsaka tsaki triterpenes da triterpenes acidic.Abubuwan triterpenes na acidic sun haɗa da nau'o'i daban-daban kamar Ganoderic Acid A, Ganoderic Acid B, Ganoderic Acid F, da dai sauransu. Ko da kuwa ko Ganoderic Acid A ko Ganoderic Acid B, dukansu 'yan uwa ne na triterpene.Kowannensu yana da nau'ikan sinadarai daban-daban kuma, saboda haka, suna da ayyukan ilimin lissafi daban-daban.

Daga cikin nau'ikan nau'ikan nau'ikan nau'ikan triterpene sama da 300, Ganoderic Acid A a halin yanzu shine mafi yawan bincike kuma shine fili triterpene tare da tasirin gano da yawa.Yafi fitowa dagaGanoderma lucidum, kuma kusan babu shi a cikiGanoderma cuta.

Na gaba, bari mu gabatar da babban tasirin Ganoderic Acid A wanda aka nuna a ko'ina cikin binciken harhada magunguna.

Tasirin Ganoderic Acid A Kan Rauni Mai Mutuwar Hanta

A cikin 2019, an buga labarin a cikin Jarida na Jami'ar Nanjing na Magungunan Gargajiya ta Sin.Binciken ya kafa ƙungiya ta al'ada, ƙungiyar ƙira, ƙungiyar Ganoderic Acid A mai ƙarancin kashi (20mg / kg), da kuma ƙungiyar Ganoderic Acid A (40mg / kg).Ya yi nazarin tasirin Ganoderic Acid A akan berayen da aka yi musu allura tare da D-Galactosamine (D-GaIN) da Lipopolysaccharides (LPS), da rawar da take takawa da kuma hanyoyin da ke da alaƙa da cutar hanta da D-GaIN/LPS ta haifar a cikin mice.Binciken ya gano cewa Ganoderic Acid A yana da tasirin kariya daga raunin hanta wanda D-GaIN / LPS ya haifar a cikin mice.An yi imani da cewa wannan sakamako na iya kasancewa da alaƙa da ka'idar hanyar siginar NLRP3 / NF-KB.[1]

Sakamakon Anti-Tumor na Ganoderic Acid A

Nemo ingantaccen magani don wahala-da-wayar m meningiomas ya kasance begen likitoci da marasa lafiya koyaushe.Ganodermaya kasance mai tasiri koyaushe wajen hana ciwace-ciwacen daji da kuma dawo da aikin tiyata bayan ciwon daji.

A cikin 2019, wani rahoto da aka buga a cikin "Clinical and Translational Oncology" ta hanyar kwakwalwa da ƙungiyar ƙwayar cuta ta kashin baya a Cibiyar Ciwon daji ta Hollings (cibiyar ciwon daji da Cibiyar Ciwon daji ta Ƙasar Amurka ta tsara) ya nuna cewa ko Ganoderic Acid A ko Ganoderic. Ana amfani da Acid DM shi kaɗai, duka biyun suna iya hana haɓakar cutar sankarau da kuma tsawaita lokacin rayuwa na beraye masu ɗauke da ƙari.Tsarin aikin yana da alaƙa da sake kunnawa na ƙwayar ƙwayar ƙwayar cuta ta NDRG2.[2]

(An ɗauki abubuwan hoto daga gidan yanar gizon mujallu na hukuma)

A cikin 2021, an buga labarin a cikin Jarida ta Sinawa na Clinical Pharmacology.Binciken ya kafa ƙungiyar gwaji ta amfani da 0.5mmol/L na Ganoderic Acid A don shiga cikin ƙwayoyin glioma C6 na bera.An gano cewa ɓangaren ɓangaren ƙwayar ƙwayar cuta a cikin ƙungiyar gwaji na glioma ratsan ya kasance mafi ƙanƙanta fiye da na ƙungiyar kulawa, kuma an rage yawan adadin CD31 mai kyau na maganganu idan aka kwatanta da ƙungiyar kulawa.An yanke shawarar cewa Ganoderic Acid A na iya hana yaduwar ƙwayoyin bera glioma C6 a cikin vitro, kuma a lokaci guda, yana iya hana haɓakar ƙirar glioma a cikin berayen ta hanyar toshe samuwar tasoshin jini.[3]

Tasirin Ganoderic Acid A Kan Tsarin Jijiya

A cikin 2015, wani labarin ilimi da aka buga a cikin Journal of Mudanjiang Medical University ya ruwaito cewa ta hanyar gwaje-gwaje, an gano cewa 50μg / ml na Ganoderic Acid A zai iya ƙara yawan rayuwa na hippocampal neurons, inganta aikin SOD na epileptic-kamar hippocampal neurons, da kuma ƙara ƙarfin mitochondrial membrane.An nuna cewa Ganoderic Acid A na iya karewa rashin cajin jijiya na hippocampal ta hanyar hana lalacewar ƙwayoyin cuta da kuma apoptosis.[4]

TheHanaTasirin Ganoderic Acid A akan Fibrosis na Renal da Ciwon Koda na Polycystic

Tawagar karkashin jagorancin Farfesa Yang Baoxue, shugaban Sashen Kimiyyar Magunguna a Makarantar Kimiyyar Kiwon Lafiya ta Jami'ar Peking, ta buga takardu guda biyu a jere a cikin "Acta Pharmacologica Sinica" a karshen 2019 da farkon 2020. Takardun sun tabbatar da cikas. sakamakonGanodermaakan fibrosis na koda da cututtukan koda na polycystic, tare da Ganoderic Acid A shine babban sashi mai tasiri.[5]

Bugu da kari, Ganoderic Acid A zai iya hana sakin histamine na salula, yana inganta aikin gabobin daban-daban a cikin tsarin narkewa, kuma yana da tasiri kamar rage yawan lipids na jini, rage hawan jini, kare hanta, da daidaita aikin hanta.[6]

Gabaɗaya, tabbas yana da kyau a sami babban abun ciki naGanodermatriterpenes.Ƙara Ganoderic Acid A, wanda aka sani don daidaitattun tasiri da tasiri mai karfi, zai inganta ingancin man mai.

Magana:

1. Wei Hao, et al."Tasirin kariya na Ganoderic Acid A kan raunin hanta wanda D-galactosamine / lipopolysaccharide ya haifar a cikin mice," Journal of Nanjing University of Traditional Chinese Medicine, 2019, 35 (4), p.432.

2.Wu Tingyao."Sabuwar bincike: Masanan Amurka sun tabbatar da cewa Ganoderic Acid A da DM suna tsara kwayar cutar ciwon daji ta NDRG2, suna hana ci gaban meningiomas masu cutarwa," GanoHerb Organic Ganoderma, 2020-6-12.

3.Yang Xin, Huang Qin, Pan Xiaomei."Tasirin hanawa na Ganoderic Acid A kan haɓakar glioma a cikin berayen," Jarida ta Sinawa na Clinical Pharmacology, 2021, 37 (8), p.997-998.

4.Wu Rongliang, Liu Junxing."Tasirin Ganoderic Acid A a kan epileptic-kamar fitarwa neurons hippocampal," Journal of Mudanjiang Medical University, 2015, 36 (2), p.8.

5.Wu Tingyao."Sabon bincike: Tawagar Farfesa Yang Baoxue a Jami'ar Peking ta tabbatar da cewa Ganoderic Acid A shine babban bangaren Ganoderma triterpenes don kare koda," GanoHerb Organic Ganoderma, 2020-4-16.

6. Wei Hao, et al."Tasirin kariya na Ganoderic Acid A akan raunin hanta wanda D-galactosamine / lipopolysaccharide ya haifar a cikin mice," Journal of Nanjing University of Traditional Chinese Medicine, 2019, 35 (4), p.433