May noJulayi 2015/University of Haifa, Israel, etc./International Journal of Medicinal Mushrooms

Umbhalo/Wu Tingyao

Izinkinga zomtholampilo ezihlobene nesifo sikashukela zingabandakanya i-cardiovascular autonomic neuropathy, neuropathy, nephropathy, anemia, kanye nokuzivikela okubuthakathaka.Iglucose eningi kakhulu egazini izobhubhisa amangqamuzana abomvu egazi;imvelo ye-hyperglycemia idala inqwaba yama-radicals mahhala ukuthi ande, azophusha amangqamuzana amhlophe egazi afinyelele ku-apoptosis.Ucwaningo oluhlanganyelwe lwezazi zakwa-Israel nezase-Ukraine lubonise ukuthi isiko elicwilisiwe i-mycelium powder ofI-Ganoderma lucidumngesilinganiso esithile esiphezulu singathuthukisa ngesikhathi esisodwa lezi zinkinga ezimbili futhi sithuthukise impilo yezilwane ezinesifo sikashukela.

I-Ganoderma lucidumivikela amangqamuzana egazi abomvu futhi ivimbele i-anemia kushukela.

I-anemia ingenye yezinkinga ezivamile zesifo sikashukela.Ukugcwala okuphezulu koshukela wegazi kungabangela ukuwohloka kolwelwesi lwe-erythrocyte, okunciphisa kakhulu isikhathi sokuphila se-erythrocytes, bese kubangela i-anemia, okwenza iziguli zibe nzima ukuphefumula noma zizizwe zibuthakathaka futhi zikhathele ngenxa ye-tissue hypoxia yeselula.

Ngokocwaningo oluhlanganyelwe olwenziwe yiNyuvesi yaseHaifa kwa-Israel kanye no-Ivan Franko National University of Lviv e-Ukraine, isiko elicwilisiwe le-mycelium powder ofI-Ganoderma lucidumayikwazi ukulwa ne-anemia kuphela kodwa futhi noshukela wegazi ophansi.

Abacwaningi baqale bajova amagundane nge-synthetic antibiotic (streptozotocin) ukuze bacekele phansi amangqamuzana abo e-pancreatic islet, okwenza ukuthi akhe uhlobo lwesifo sikashukela, bese bewaphuza ngomlomo.I-Ganoderma lucidumisiko elingaphansi kwe-mycelium powder (1 g/kg/ngosuku).

Emasontweni amabili kamuva, uma kuqhathaniswa namagundane anesifo sikashukela angalashwa, iI-Ganoderma lucidumIqembu aligcini nje ukunciphisa kakhulu inkomba ye-glucose yegazi kanye nokuhlushwa kwe-glycosylated hemoglobin kodwa futhi libe namaseli abomvu egazi amaningi egazini.Amangqamuzana egazi abomvu ayengathambekele kangako “ekuphenduleni kwe-hemolytic” (okubhekisela ekuboleni okungavamile nokufa kwamangqamuzana abomvu egazi).Phakathi naleso sikhathi, ukugcwala kwe-hemoglobin ye-fetus kujwayelekile (le nkomba izokwanda ngesikhathi sokuntuleka kwegazi), futhi ikhono lomzimba lokukhiqiza amangqamuzana egazi abomvu lithuthuka kakhulu.

Ushukela wegazi wesikhathi eside uzolimaza kokubili amangqamuzana abomvu egazi namangqamuzana amhlophe egazi.Indawo kashukela ephezulu izokhuthaza ukukhiqizwa kwenani elikhulu lama-radicals mahhala (njenge-nitric oxide), okuholela ekwandeni kwenani lamangqamuzana amhlophe egazi (okungukuthi amangqamuzana omzimba omzimba anomsebenzi wokuzivikela omzimba) i-apoptosis, eholela ekwandeni ukwehla kwe-immunity.Ngakho-ke, ithimba labacwaningi liphinde labona umphumela wokuvikelaI-Ganoderma lucidumi-mycelium kumaseli amhlophe egazi ngokusebenzisa ukuhlolwa kwezilwane.

Lapho amagundane esifo sikashukela sohlobo 1 edlaI-Ganoderma lucidumi-mycelium powder amasonto amabili (umthamo: 1 g / kg / ngosuku), umsebenzi we-nitric oxide synthase emzimbeni wehla ngenkathi ama-metabolites e-nitric oxide ehla.Ngesikhathi esifanayo, inani lamangqamuzana egazi amhlophe kanye nesilinganiso se-apoptotic protein (p53) kanye ne-antiapoptotic protein (Bcl-2) kumaseli amhlophe egazi nawo asondelene nalawo amagundane avamile.Le miphumela ibonisa ukuthi ngaphansi kwemvelo kashukela ophezulu wegazi ku-vivo, i-culture mycelium powder engaphansi kwamanziI-Ganoderma luciduminganciphisa ukukhiqizwa kwezinhlobo ze-nitrogen esebenzayo futhi ivikele amangqamuzana egazi amhlophe.

Ngaphezu kweI-Ganoderma lucidum, abacwaningi baphinde babona izinhlobo ze-nitrogen ezilwa ne-anemia, i-hypoglycemic, i-anti-reactive kanye nemiphumela ephikisana ne-apoptotic yesiko elingaphansi kwamanzi i-mycelium powder.I-Agaricus brasiliensis.Ngaphansi kwemodeli yezilwane efanayo, umthamo ofanayo, nezimo zesikhathi esifanayo, nakuba isiko elingaphansi kwe-mycelium powderI-Agaricus brasiliensisibuye ibe nomphumela omuhle, kuyadabukisa ukuthi ukusebenza kwayo kuba buthaka kancane kunaleyoI-Ganoderma lucidum.

Kodwa-ke, kungakhathaliseki ukuthi i-mycelium powder yesiko elingaphansi kwamanziI-Ganoderma lucidumnomaI-Agaricus brasiliensis, zombili azinayo imiphumela emibi kushukela wegazi, amangqamuzana abomvu egazi noma amangqamuzana amhlophe egazi amagundane avamile.

Imiphumela yocwaningo engenhla ishicilelwe ku- "International Journal of Medicinal Mushrooms" ngo-2015 ezindabeni ezimbili.

[Umthombo]

1. vitak TY, et al.Umphumela Wamakhowe Emithi I-Agaricus brasiliensis kanye ne-Ganoderma lucidum (i-Basidiomycetes Ephakeme) Ohlelweni Lwe-Erythron Kumagundane Anesifo Sikashukela Esijwayelekile kanye ne-Streptozotocin.I-Int J Med Mushrooms.2015;17(3):277-86.

2. U-Yurkiv B, et al.Umthelela we-Agaricus brasiliensis kanye ne-Ganoderma lucidum Ukuphathwa Kwe-Mushroom Kwemithi ku-L-arginine/Nitric Oxide System kanye ne-Rat Leukocyte Apoptosis Ohlotsheni Lokuhlola Loku-1 Lwesifo sikashukela.I-Int J Med Mushrooms.2015;17(4):339-50.

PHELA

 
Mayelana nombhali/ Nks. Wu Tingyao
UWu Tingyao ubelokhu ebika ngolwazi lwe-Ganoderma lokuqala kusukela ngo-1999. Ungumbhali wencwadiUkwelapha nge-Ganoderma(ishicilelwe ku-People's Medical Publishing House ngo-Ephreli 2017).
 
★ Lesi sihloko sishicilelwe ngaphansi kokugunyazwa okukhethekile kombhali.★ Le misebenzi engenhla ayinakuphinda ikhiqizwe, ikhishwe noma isetshenziswe ngezinye izindlela ngaphandle kwemvume yombhali.★ Ukwephulwa kwesitatimende esingenhla, umbhali uzophishekela izibopho zayo ezingokomthetho ezihlobene.★ Umbhalo wokuqala walesi sihloko ubhalwe ngesiShayina nguWu Tingyao futhi wahunyushelwa esiNgisini ngu-Alfred Liu.Uma kukhona ukungqubuzana phakathi kokuhumusha (isiNgisi) kanye nokwangempela (isiShayina), isiShayina sangempela siyonqoba.Uma abafundi benemibuzo, sicela uthinte umbhali wokuqala, uNksz. Wu Tingyao.