NgoMeyi noJulayi 2015/iYunivesithi yaseHaifa, kwaSirayeli, njalo njalo/Ijenali yeHlabathi yamaMushrooms amayeza

Umbhalo/Wu Tingyao

Iingxaki zeklinikhi ezinxulumene nesifo seswekile zinokubandakanya i-cardiovascular autonomic neuropathy, i-neuropathy, i-nephropathy, i-anemia, kunye nobuthathaka bomzimba.I-glucose eninzi kakhulu egazini iya kutshabalalisa iiseli ezibomvu zegazi;Imekobume ye-hyperglycemia ibangela inani elikhulu leeradicals zasimahla ukuba zande, eziya kuthi zityhale iiseli ezimhlophe zegazi ukuya kwi-apoptosis.Uphononongo oludityanelweyo ngabaphengululi bakwaSirayeli nabaseUkraine lubonise ukuba inkcubeko entywilayo yemycelium powder yeI-Ganoderma lucidumkwidosi ethile ephezulu ngaxeshanye ingaphucula ezi ngxaki zimbini kwaye iphucule impilo yezilwanyana ezinesifo seswekile.

I-Ganoderma lucidumikhusela iiseli ezibomvu zegazi kwaye ikhusela i-anemia kwisifo seswekile.

I-anemia yenye yeengxaki eziqhelekileyo zesifo seswekile.Uxinzelelo oluphezulu lweswekile yegazi lunokubangela ukuwohloka kwenwebu ye-erythrocyte, enciphisa kakhulu ubomi be-erythrocytes, kwaye emva koko ibangele i-anemia, eyenza izigulane kube nzima ukuphefumla okanye ukuziva zibuthathaka kwaye zidiniwe ngenxa ye-hypoxia yeselula yezicubu.

Ngokutsho kophononongo oludibeneyo oluqhutywe yiYunivesithi yaseHaifa kwaSirayeli kunye neYunivesithi yeSizwe ye-Ivan Franko yaseLviv e-Ukraine, inkcubeko ye-mycelium powder ephantsi kwamanzi.I-Ganoderma lucidumayinakulwa kuphela i-anemia kodwa iyancipha iswekile yegazi.

Abaphandi baqala ngokutofa iimpuku nge-antibiotiki eyenziwe (i-streptozotocin) ukutshabalalisa iiseli zabo ze-pancreatic islet, zibangele ukuba zenze uhlobo lwe-1 yeswekile, kwaye emva koko babanyanga ngomlomo.I-Ganoderma luciduminkcubeko ephantsi komhlaba umgubo we-mycelium (1 g/kg/ngosuku).

Kwiiveki ezimbini kamva, xa kuthelekiswa neempuku zesifo seswekile ezingaphathwanga, iI-Ganoderma lucidumIqela alizange linciphise kakhulu i-glucose index kunye ne-glycosylated hemoglobin concentration kodwa libe neeseli ezibomvu zegazi ezininzi.Iiseli zegazi ezibomvu zazingafaneli kakhulu "kwi-hemolytic reaction" (ibhekisa ekuboleni okungaqhelekanga kunye nokufa kweeseli ezibomvu zegazi).Okwangoku, ukuxinwa kwe-hemoglobin ye-fetal kuqhelekileyo (esi salathisi siya kwanda ngexesha le-anemia), kwaye amandla omzimba wokuvelisa iiseli ezibomvu zegazi aphuculwe kakhulu.

Ixesha elide iswekile ephezulu iya kulimaza zombini iiseli ezibomvu zegazi kunye neeseli ezimhlophe zegazi.Imekobume ephezulu yeswekile yegazi iya kukhuthaza ukuveliswa kwenani elikhulu leeradicals zasimahla (ezifana ne-nitric oxide), okukhokelela ekwandeni kwenani leeseli ezimhlophe zegazi (oko kukuthi iiseli zokhuselo lomzimba ezinomsebenzi wokuzivikela komzimba) i-apoptosis, ekhokelela ekubeni ukuhla kwi-immunity.Ngoko ke, iqela lophando liye laqaphela umphumo wokukhuselaI-Ganoderma lucidummycelium kwiiseli ezimhlophe zegazi ngovavanyo lwezilwanyana.

Xa iimpuku zesifo seswekile zohlobo loku-1 zityileI-Ganoderma lucidumi-mycelium powder kwiiveki ezimbini (i-dose: 1 g / kg / ngosuku), umsebenzi we-nitric oxide synthase emzimbeni wehla ngelixa i-metabolites ye-nitric oxide iyancipha.Ngexesha elifanayo, inani leeseli ezimhlophe zegazi kunye nomlinganiselo weprotheni ye-apoptotic (p53) kunye neprotheni ye-antiapoptotic (Bcl-2) kwiiseli ezimhlophe zegazi nazo zisondele kakhulu kwiigundane eziqhelekileyo.Ezi ziphumo zibonisa ukuba phantsi kokusingqongileyo kweswekile yegazi ephezulu kwi-vivo, i-mycelium yenkcubeko engaphantsi kwamanzi engumguboI-Ganoderma luciduminokunciphisa ukuveliswa kweentlobo ze-nitrogen ezisebenzayo kunye nokukhusela iiseli ezimhlophe zegazi.

Ukwengeza kwiI-Ganoderma lucidum, abaphandi baye baqaphela i-anti-anemia, i-hypoglycemic, iintlobo ze-nitrogen ezichasene ne-anti-reactive kunye nemiphumo echasene ne-apoptotic yenkcubeko ephantsi kwamanzi i-mycelium powderAgaricus brasiliensis.Ngaphantsi kwemodeli yesilwanyana esifanayo, idosi efanayo, kunye neemeko zexesha elifanayo, nangona inkcubeko ephantsi kwamanzi i-mycelium powderAgaricus brasiliensisnayo inesiphumo esihle, kulilusizi ukuba ukusebenza kwayo kubuthathaka kancinci kunokoI-Ganoderma lucidum.

Nangona kunjalo, kungakhathaliseki ukuba yinkcubeko ephantsi kwe-mycelium powderI-Ganoderma lucidumokanyeAgaricus brasiliensis, zombini azikho imiphumo emibi kwishukela egazini, iiseli ezibomvu zegazi okanye iiseli ezimhlophe zegazi zeempuku eziqhelekileyo.

Iziphumo zophando ezingentla zipapashwe kwi-"International Journal of Medicinal Mushrooms" kwi-2015 kwimiba emibini.

[Umthombo]

1. vitak TY, et al.Umphumo wamaMushrooms amayeza i-Agaricus brasiliensis kunye ne-Ganoderma lucidum (i-Basidiomycetes ephezulu) kwi-Erythron System kwi-Normal kunye ne-Streptozotocin-Induced Diabetic Rats.Int J Med Mushrooms.2015;17(3):277-86.

2. Yurkiv B, et al.Umphumo we-Agaricus brasiliensis kunye ne-Ganoderma lucidum Ulawulo lwe-Mushroom yoNyango kwi-L-arginine / i-Nitric Oxide System kunye ne-Rat Leukocyte Apoptosis kwi-Experimental Type 1 Diabetes Mellitus.Int J Med Mushrooms.2015;17(4):339-50.

ISIPHELO

 
Malunga nombhali/ Nksz. Wu Tingyao
UWu Tingyao unike ingxelo ngolwazi lweGanoderma lokuqala ukusukela ngo-1999. Ungumbhali wencwadiUkunyanga ngeGanoderma(ipapashwe kwiNdlu yePeople's Medical Publishing House ngo-Epreli 2017).
 
★ Eli nqaku lipapashwe phantsi kogunyaziso olulodwa lombhali.★ Le misebenzi ingasentla ayinakuphinda iveliswe, icatshulwe okanye isetyenziswe ngezinye iindlela ngaphandle kokugunyaziswa ngumbhali.★ Ukwaphulwa kwengxelo engentla, umbhali uya kulandela uxanduva olunxulumene nomthetho.★ Umbhalo wokuqala weli nqaku ubhalwe ngesiTshayina nguWu Tingyao waza waguqulelwa kwisiNgesi nguAlfred Liu.Ukuba kukho nakuphi na ukungangqinelani phakathi kwenguqulelo (isiNgesi) kunye neyoqobo (isiTshayina), isiTshayina sokuqala siya koyisa.Ukuba abafundi banayo nayiphi na imibuzo, nceda uqhagamshelane nombhali wokuqala, uNks. Wu Tingyao.