May ndi July 2015/University of Haifa, Israel, etc./International Journal of Medicinal Mushrooms

Mawu/Wu Tingyao

Mavuto azachipatala okhudzana ndi matenda a shuga angaphatikizepo mtima wamtima autonomic neuropathy, neuropathy, nephropathy, kuchepa magazi, komanso kufooka kwa chitetezo chamthupi.Glucose wambiri m'magazi amawononga maselo ofiira a magazi;chilengedwe cha hyperglycemia chimayambitsa kuchuluka kwa ma free radicals kuti achuluke, zomwe zimakankhira maselo oyera amagazi kupita ku apoptosis.Kafukufuku wophatikizana ndi akatswiri a Israeli ndi Chiyukireniya wasonyeza kuti chikhalidwe cha mycelium chamira chaGanoderma lucidumpa mlingo winawake mkulu akhoza imodzi kusintha mavuto awiriwa ndi kusintha thanzi la matenda a shuga nyama.

Ganoderma lucidumimateteza maselo ofiira a magazi komanso kupewa kuchepa kwa magazi m'thupi la matenda a shuga.

Kuperewera kwa magazi m'thupi ndi chimodzi mwazovuta zomwe zimachitika mu shuga.Kuchuluka kwa shuga m'magazi kungayambitse kuwonongeka kwa erythrocyte membrane, komwe kumafupikitsa moyo wa erythrocytes, ndiyeno kumayambitsa kuchepa kwa magazi m'thupi, zomwe zimapangitsa odwala kukhala ovuta kupuma kapena kukhala ofooka komanso otopa chifukwa cha hypoxia yama cell.

Malinga ndi kafukufuku ophatikizana wochitidwa ndi University of Haifa ku Israel ndi Ivan Franko National University of Lviv ku Ukraine, chikhalidwe chomira mycelium ufa waGanoderma lucidumsangathe kulimbana ndi kuchepa kwa magazi m'thupi komanso kuchepetsa shuga.

Ofufuzawo adayamba kubaya makoswe ndi mankhwala ophatikizika (streptozotocin) kuti awononge maselo awo a pancreatic islet, kuwapangitsa kupanga mtundu wa shuga 1, kenako adawachiritsa pakamwa.Ganoderma lucidumufa wa mycelium womira (1 g/kg/tsiku).

Patatha milungu iwiri, poyerekeza ndi makoswe osachiritsika a matenda a shuga, aGanoderma lucidumGulu silinangochepetsa kuchuluka kwa shuga m'magazi ndi glycosylated hemoglobin, komanso linali ndi maselo ofiira ambiri m'magazi.Maselo ofiira a m'magazi anali ochepa kwambiri "hemolytic reaction" (kutanthauza kuwonongeka kwachilendo ndi imfa ya maselo ofiira a magazi).Pakadali pano, kuchuluka kwa hemoglobin ya fetal ndikwabwinobwino (chilozerachi chidzawonjezeka panthawi ya kuchepa kwa magazi), ndipo mphamvu ya thupi yotulutsa maselo ofiira amagazi imakhala bwino.

Shuga wokwera m'magazi kwa nthawi yayitali amawononga maselo ofiira am'magazi ndi maselo oyera.Kuchuluka kwa shuga m'magazi kudzalimbikitsa kupanga kuchuluka kwa ma free radicals (monga nitric oxide), zomwe zimapangitsa kuti kuchuluka kwa maselo oyera amwazi (mwachitsanzo, maselo a chitetezo chamthupi) apoptosis, zomwe zimabweretsa kuchepa kwa chitetezo chokwanira.Choncho, gulu lofufuza lidawonanso chitetezo chaGanoderma lucidummycelium pa maselo oyera a magazi kupyolera mu kuyesa nyama.

Pamene makoswe amtundu woyamba adadyaGanoderma lucidummycelium ufa kwa milungu iwiri (mlingo: 1 g/kg/tsiku), ntchito ya nitric oxide synthase m’thupi inachepa pamene metabolites ya nitric oxide inachepa.Panthawi imodzimodziyo, chiwerengero cha maselo oyera a magazi ndi chiŵerengero cha mapuloteni a apoptotic (p53) ndi mapuloteni a antiapoptotic (Bcl-2) m'maselo oyera a magazi amakhalanso pafupi ndi makoswe abwino.Zotsatirazi zikuwonetsa kuti pansi pa chilengedwe cha shuga wambiri m'magazi mu vivo, chikhalidwe chomira cha mycelium ufa waGanoderma lucidumimatha kuchepetsa kupanga kwa mitundu ya nayitrogeni yokhazikika komanso kuteteza maselo oyera amagazi.

Kuphatikiza paGanoderma lucidum, ofufuzawo adawonanso za anti-anemia, hypoglycemic, anti-reactive nitrogen mitundu ndi anti-apoptotic zotsatira za chikhalidwe chozama cha mycelium ufa waAgaricus brasiliensis.Pansi pa chitsanzo cha nyama chomwecho, mlingo womwewo, ndi nthawi yomweyi, ngakhale kuti chikhalidwe cha mycelium chimakwirira.Agaricus brasiliensisilinso ndi zotsatira zabwino, ndizomvetsa chisoni kuti machitidwe ake ndi ofooka pang'ono kuposa aGanoderma lucidum.

Komabe, ziribe kanthu kaya ndi m'madzi chikhalidwe mycelium ufa waGanoderma lucidumkapenaAgaricus brasiliensis, onsewa alibe zotsatira zoyipa pa shuga wamagazi, maselo ofiira amwazi kapena maselo oyera amagazi a makoswe abwinobwino.

Zotsatira zafukufuku zomwe zili pamwambazi zasindikizidwa mu "International Journal of Medicinal Mushrooms" mu 2015 m'nkhani ziwiri.

[Chitsime]

1. vitak TY, et al.Zotsatira za Bowa Wamankhwala Agaricus brasiliensis ndi Ganoderma lucidum (Higher Basidiomycetes) pa Erythron System mu Normal and Streptozotocin-Induced Diabetic Rats.Int J Med Bowa.2015;17(3):277-86.

2. Yurkiv B, ndi al.Zotsatira za Agaricus brasiliensis ndi Ganoderma lucidum Medicinal Mushroom Administration pa L-arginine /Nitric Oxide System ndi Rat Leukocyte Apoptosis mu Experimental Type 1 Diabetes Mellitus.Int J Med Bowa.2015;17(4):339-50.

TSIRIZA

 
Za wolemba/ Mayi Wu Tingyao
Wu Tingyao wakhala akufotokoza zambiri za Ganoderma kuyambira 1999. Iye ndi mlembi wa bukuli.Kuchiza ndi Ganoderma(lofalitsidwa mu The People's Medical Publishing House mu April 2017).
 
★ Nkhaniyi yasindikizidwa pansi pa chilolezo cha wolemba.★ Ntchito zomwe zili pamwambazi sizingathe kupangidwanso, kuchotsedwa kapena kugwiritsidwa ntchito mwanjira ina popanda chilolezo cha wolemba.★ Kuphwanya mawu omwe ali pamwambawa, wolemba adzakwaniritsa udindo wake walamulo.★ Zolemba zoyambirira za nkhaniyi zidalembedwa m'Chitchaina ndi Wu Tingyao ndikumasulira m'Chingerezi ndi Alfred Liu.Ngati pali kusiyana kulikonse pakati pa kumasulira (Chingerezi) ndi choyambirira (Chitchaina), Chitchaina choyambirira chidzapambana.Ngati owerenga ali ndi mafunso, lemberani wolemba woyamba, Mayi Wu Tingyao.