Ukuboza 13, 2019 / Kaminuza ya Yeungnam, nibindi / Raporo yubumenyi

Inyandiko / Wu Tingyao

Nkuko ubuzima bwa buri munsi bwabantu bose bubabajwe nigitabo cya coronavirus ya 2019, haracyari virusi nyinshi zidakira.Virusi ya Dengue yanduza abantu ikoresheje imibu ni imwe muri zo.

Kimwe na virusi zose, virusi ya dengue yanduza abantu ikoresheje imibu nayo ikoresha selile kugirango yororoke ibisekuruza bizaza.Kubwibyo, uburyo bwo kubangamira uburyo bwo kwigana virusi mu ngirabuzimafatizo byabaye ingamba nyamukuru yo guteza imbere imiti ifitanye isano.

Kugeza ubu, ubushakashatsi bwinshi bwibanze kuri virusi ya dengue NS2B-NS3, kubera ko ari ikintu cy'ingenzi kuri virusi ya dengue kugira ngo irangize inzira yo kwigana.Hatabigizemo uruhare, virusi ntishobora kubyara kugirango yanduze izindi selile.

Nk’uko ubushakashatsi bwasohotse muri “Scientific Reports” mu Kuboza 2019 bubitangaza, Ikigo cy’ibinyabuzima cya kaminuza ya Yeungnam muri Koreya yepfo n’amakipe yaturutse mu Buhinde na Turukiya basuzumye amoko 22 ya triterpenoide yo mu mubiri wera imbuto.Ganoderma Lucidumugasanga bane muribo bagaragaje ko bashobora kubuza ibikorwa bya protease NS2B-NS3.

Hifashishijwe ubushakashatsi bwa vitro kugirango bigereranye uburyo virusi yanduza selile mu mubiri, abashakashatsi bakomeje gusuzuma ubwoko bubiri bwaGanoderma lucidumtriterpenoids:

Abashakashatsi babanje gutsimbataza virusi ya dengue yo mu bwoko bwa 2 (DENV-2, ubwoko bushobora gutera indwara zikomeye) hamwe na selile zabantu kumasaha 1, hanyuma babavura bafite ibitekerezo bitandukanye (25 cyangwa 50 μM) byaGanoderma lucidumtriterpenoide kumasaha 1.Nyuma yamasaha 24, basesenguye igipimo cya selile zanduye virusi.

Ibisubizo byerekanye ko ganodermanontriol ishobora kugabanya umuvuduko wanduye selile hafi 25% (25μM) cyangwa 45% (50μM) mugihe acide ganoderic aside C2 idafite ingaruka nyinshi zo kubuza.

Ibisubizo by'ubu bushakashatsi biduha ubundi buryo bushoboka bwa virusi yaGanoderma lucidumkandi utange n'amahirwe mashya yo kuvura umuriro wa dengue, kuberako nta muti wihariye uhari.

Ibyavuzwe haruguru ni igishushanyo mbonera cyintambwe zo gusuzuma ibiyobyabwenge byabakandida kugirango babuze virusi ya dengueGanoderma lucidumtriterpenoids hamwe na protease ya NS2B-NS3 nkintego.Imbonerahamwe y'ibarurishamibare iri hepfo iburyo yerekana igipimo cyo guhagarika ganodermanontriol ku ngirabuzimafatizo zanduye virusi ya dengue.

[Source] Bharadwaj S, n'abandi.Ivumburwa rya Ganoderma lucidum triterpenoide nkibishobora gukumira virusi ya Dengue NS2B-NS3 protease.Sci Rep. 2019 Ukuboza 13; 9 (1): 19059.doi: 10.1038 / s41598-019-55723-5.

IHEREZO
Ibyerekeye umwanditsi / Madamu Wu Tingyao
Wu Tingyao yagiye atanga amakuru ku makuru ya Ganoderma lucidum kuva mu 1999. Ni umwanditsi wa Healing hamwe na Ganoderma (yasohotse mu nzu y’ubuvuzi y’abaturage muri Mata 2017).

★ Iyi ngingo yasohowe ku ruhushya rwihariye rw’umwanditsi works Ibikorwa byavuzwe haruguru ntibishobora gusubirwamo, gucibwa cyangwa gukoreshwa mu bundi buryo utabiherewe uburenganzira n’umwanditsi ★ Kurenga ku magambo yavuzwe haruguru, umwanditsi azakomeza inshingano zijyanye n’amategeko ★ Umwimerere inyandiko yiyi ngingo yanditswe mu gishinwa na Wu Tingyao ihindurwa mu Cyongereza na Alfred Liu.Niba hari itandukaniro riri hagati yubuhinduzi (icyongereza) numwimerere (igishinwa), igishinwa cyumwimerere kizatsinda.Niba abasomyi bafite ikibazo, nyamuneka hamagara umwanditsi wambere, Madamu Wu Tingyao.