◎ Sengoliloeng sena se phatlalalitsoe ka lekhetlo la pele ka Sechaena sa setso Tokollong ea 96 ea “Khanoderma” (December 2022), mme e phatlalalitsoe ka lekhetlo la pele ka Sechaena se nolofalitsoeng ho “ganodermanews.com” (Pherekhong 2023), ’me joale e hatisitsoe mona ka tumello ea mongoli.

Sehloohong se reng “Motheo oaReishiho thibela ntaramane ─ Qi e lekaneng ea bophelo bo botle ka hare ho 'mele e tla thibela ho hlaseloa ha lintho tsa pathogenic" khatisong ea 46 ea "Khanoderma"Ka 2009, ke boletse hore khopolo ea meriana ea setso ea Sechaena e lumela hore bophelo bo botle le maloetse ke tsa linaha tse fapaneng tsa "khohlano pakeng tsa bophelo bo botle le pathogenic qi".Har'a tsona, "qi e phetseng hantle" e bolela bokhoni ba 'mele oa motho ho hanela mafu,' me "pathogenic qi" ka kakaretso e bolela likokoana-hloko le libaktheria tse hlaselang 'mele oa motho kapa lihlahala tse hlahisang' meleng.

Ka mantsoe a mang, motho o boemong bo botle hobane qi e lekaneng ea bophelo bo botle ka hare ho 'mele e thibela ho hlaseloa ha lintho tsa pathogenic, ke hore,' mele oa motho o na le matla a matla a ho hanyetsa maloetse, e leng ho sa bolele hore ha ho na pathogenic qi. 'meleng empa ho bolela hore pathogenic qi' meleng e ke ke ea hatella qi e phetseng hantle;motho o boemong ba ho kula hobane mabaka a likokoana-hloko a hlasela 'mele o haelloang ke qi e phetseng hantle, ke hore, ho haelloa ke bophelo bo botle ba qi ho fokolisa ho hanyetsa' mele oa lefu lena, 'me ho bokellana ha lintho tsa pathogenic' meleng ho lebisa ho mafu.Mokhoa o nepahetseng oa phekolo ke ho felisa ka ho feletseng mabaka a pathogenic.Leha ho le joalo, ho fihlela joale, ha ho meriana ea Bophirimela kapa meriana ea setso ea Machaena e ka felisang ka ho feletseng mabaka a mang a pathogenic.

Na ha ho joalo ka ts'oaetso e ncha ea coronavirus ea kajeno?Ka lebaka la khaello ea litlhare tse thibelang likokoana-hloko, ha ho meriana ea bophirimela kapa meriana ea setso ea Chaena e ka bolaeang likokoana-hloko ka ho feletseng.Lebaka leo ka lona batho ba nang le tšoaetso ba ka hlaphoheloa ke ho itšetleha ka ho matlafatsa tšireletso ea 'mele (qi e phetseng hantle) motheong oa phekolo ea matšoao (ho imoloha ha matšoao a sa phutholohang) ho qetella ho hlakoloa kokoana-hloko (pathogenic qi).

Tsamaiso e matla ea 'mele ea ho itšireletsa mafung e etsa hore ho be thata hore likokoana-hloko li bake maloetse. 

Coronavirus e ncha (SARS-CoV-2) e tšoaelitse le ho senya lefatše ka lilemo tse 3.Qetellong ea 2022, batho ba fetang limilione tse 600 ba tšoaelitsoe mme ba fetang limilione tse 6 ba shoele.Hajoale, mefuta e fapaneng ea Omicron ea "coronavirus" e ncha e ntse e ata lefatšeng ka bophara.Le hoja sekhahla sa bona sa pathogenicity le lefu li fokotsehile, se tšoaetsanoa haholo 'me sekhahla sa tšoaetso se phahame haholo.

Lithethefatsi tse seng li ntse li le teng tsa antiviral li ke ke tsa bolaea likokoana-hloko tse itseng, empa li ka thibela ho ata ha livaerase feela.Ntle le mehato e tloaelehileng ea thibelo e kang ho roala limaske, ho ela hloko bohloeki ba matsoho, ho boloka sebaka sa boiketlo ba sechaba, le ho qoba likopano, ntho ea bohlokoahali ke "ho matlafatsa qi e phetseng hantle".

Ho itšireletsa mafung ho bolela bokhoni ba sesole sa 'mele ho hanela le ho felisa tlhaselo ea likokoana-hloko tse kang libaktheria le likokoana-hloko, ho tlosa botsofali, lisele tse shoeleng kapa tse fetotsoeng' meleng le lintho tse bakang ho kula, ho boloka botsitso ba tikoloho e ka hare ea 'mele. boloka mmele o phetse hantle.

Lintho tse ngata tse kang khatello ea kelello, matšoenyeho, ho sebetsa ho feta tekano, khaello ea phepo e nepahetseng, bothata ba ho robala, ho se ikoetlise, botsofali, maloetse le lithethefatsi li ka ama tšireletso ea ’mele ’me tsa baka ho se sebetse hantle ha ’mele oa ho itšireletsa mafung kapa ho se sebetse hantle ha ’mele oa ho itšireletsa mafung.

Nakong ea seoa sena, batho ba bang ba neng ba e-na le kamano e haufi le batho ba tšoaelitsoeng ke "coronavirus" e ncha ha baa ka ba kula 'me ea e-ba linyeoe tsa asymptomatic;batho ba bang ba ile ba kula empa ba e-na le matšoao a fokolang.

Lebaka leo ka lona batho bana ba se nang matšoao kapa ba e-na le matšoao a bonolo ke hore tšireletso e matla ea 'mele (e phetseng hantle qi) e hatella kokoana-hloko (pathogenic qi).Ha ho na le qi e lekaneng ea bophelo bo botle 'meleng, mabaka a pathogenic ha a na mokhoa oa ho hlasela' mele.

Setšoantšo sa Reishi se matlafatsang bophelo bo botle ba qi le ho felisa likokoana-hloko

Reishie matlafatsa sesole sa 'mele le ho thibela tšoaetso ea kokoana-hloko.

Reishie na le phello ea 'mele ea ho itšireletsa mafung.Ntlha ea pele, Reishi e ka ntlafatsa ts'ebetso ea 'mele e sa tsitsang ea' mele ea ho itšireletsa mafung, ho kenyelletsa le ho khothalletsa ho hōla, ho khetholla le ho sebetsa ha lisele tsa dendritic, ho matlafatsa ts'ebetso ea ho bolaea macrophages ea mononuclear le lisele tse bolaeang tsa tlhaho, 'me e ka felisa ka ho toba likokoana-hloko tse hlaselang.

Ea bobeli,Reishie ntlafatsa ts'ebetso ea ts'ireletso ea li-humoral le ts'ireletso ea lisele tse kang ho khothalletsa ho ata ha lisele tsa B, ho khothalletsa tlhahiso ea immunoglobulin (antibody) IgM le IgG, ho khothalletsa ho ata ha lisele tsa T, ho matlafatsa ts'ebetso ea ho bolaea lisele tsa cytotoxic T (CTL), le ho khothalletsa tlhahiso ea li-cytokine tse kang interleukin-1 (IL-1), interleukin-2 (IL-2) le interferon-gamma (IFN-gamma).

Liphuputso li bontšitse hore Reishi e ka thibela tšireletso ea 'mele ea lisele tsa hlahala, empa hore na e na le phello e tšoanang ho phonyoha ha likokoana-hloko tsa likokoana-hloko e ntse e tsoela pele ho ithutoa.Leha ho le joalo, bakeng sa hypofunction ea 'mele ea ho itšireletsa mafung e bakoang ke mabaka a fapaneng a kang khatello ea kelello, matšoenyeho, ho sebetsa ho feta tekano, botsofali, maloetse le lithethefatsi,Reishie 'nile ea pakoa hore e thusa ho tsosolosa ts'ebetso e tloaelehileng ea' mele ea ho itšireletsa mafung.

Tšusumetso e matlafatsang 'mele ea Reishi e fana ka motheo oa theory bakeng sa thibelo ea eona ea tšoaetso ea coronavirus.

Reishie khutsisa moea, e hanela khatello ea maikutlo le ho matlafatsa sesole sa 'mele.

Nakong ea seoa sa COVID-19, batho ba bang ba bile le tšabo, tsitsipano, matšoenyeho, mathata a boroko, esita le khatello ea maikutlo ka lebaka la khatello ea kelello e bakiloeng ke ts'oaetso ea COVID-19 kapa mehato ea thibelo le taolo ea seoa, tseo kaofela li tla ama boits'ireletso ba mmele.

Sehloohong se reng “Liteko tsa Liphoofolo le Liteko tsa Batho tsaMofuta oa "Ganoderma Lucidum".Khahlanong le Khatello ea 'mele ea ho Itšireletsa 'meleng e bakoang ke khatello ea kelello” tokollong ea bo63 eaKhanodermaka 2014, ke ile ka bua ka liteko pharmacological horeGanoderma lucidume ntlafalitse tšebetso ea 'mele ea ho itšireletsa mafung ea litoeba tse bakoang ke khatello ea maikutlo.Pampiri ena e bontša hore khatello ea kelello ea 'mele le ea kelello e hlahisoang ke koetliso e matla haholo e ka thibela ts'ebetso ea' mele ea ho itšireletsa mafung ea baatlelete, empa Ganoderma lucidum e ka ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung.

Liphello tsena li amana le likarolo tse matlafatsang 'mele le tse khutsisang moea tsaReishi.Ka lentsoe le leng, Reishi e thusa ho fokotsa khatello ea kelello ka litlamorao tsa eona tse kang sedative hypnosis, anti-anxiety, le anti-depression.Ka hona, ha ho thata ho nahana hore ts'ebetso e khutsitseng ea moea ea Reishi e ka fokotsa khatello ea kelello e bakoang ke seoa sa COVID-19 le ho matlafatsa sesole sa 'mele.

Ganoderma lucidume boetse e na le phello ea anti-novel coronavirus.

Ganoderma lucidume tsebahala haholo ka thepa ea eona ea antiviral.Nakong ea seoa sena, batho ba amehile haholo ka hore naGanoderma lucidume na le phello ea anti-novel coronavirus (SARS-Cov-2).

Lipatlisiso tse entsoeng ke litsebi tse tsoang Academia Sinica, Taiwan tse hatisitsoeng ho "Proceedings of the National Academy of Sciences" Ka 2021 li pakile seo.Ganoderma lucidumpolysaccharide (RF3) e na le litlamorao tse hlakileng tsa anti-novel coronavirus in vivo le in vitro antiviral liteko, 'me ha e chefo.

Boithuto bo bonts'itse hore RF3 (2 μg/ml) e na le phello e kholo ea antiviral ho SARS-Cov-2 e hlahisitsoeng ka har'a vitro, mme e ntse e na le ts'ebetso ea inhibitory ha e hlakotsoe makhetlo a 1280, empa ha e na chefo ho Vero E6 e amohelang vaerase. lisele.Tsamaiso ea molomo eaGanoderma lucidumpolysaccharide RF3 (ka tekanyo ea letsatsi le letsatsi ea 30 mg/kg) e ka fokotsa bongata ba kokoana-hloko (liteng) matšoafong a li-hamster tse tšoaelitsoeng ke kokoana-hloko ea SARS-Cov-2, empa boima ba liphoofolo tsa liteko ha bo fokotsehe, ho bontša horeGanoderma lucidumpolysaccharide ha e na chefo (joalokaha ho bontšitsoe setšoantšong se ka tlase) [1].

Phello ea anti-novel coronavirus ea tse boletsoeng ka holimoGanoderma lucidumpolysaccharides in vivo le in vitro e fana ka motheo oa theory bakeng sa "ho felisa lintlha tsa pathogenic" bakeng sa thibelo ea eona ea tšoaetso e ncha ea coronavirus.

Liphetho tsa liteko tsaGanoderma lucidumli-polysaccharides khahlano le coronavirus e ncha ea vivo le in vitro

Ganoderma lucidume ntlafatsa phello ea ente ea kokoana-hloko.

Liente tsa kokoana-hloko ke litokisetso tsa autoimmune tse entsoeng ka ho fokotsa, ho kenya tšebetsong kapa ho fetola liphatsa tsa lefutso livaerase kapa likarolo tsa tsona ho thibela tšoaetso ea vaerase.

Ente e boloka litšobotsi tsa kokoana-hloko kapa likarolo tsa eona ho matlafatsa sesole sa 'mele.Ho entoa khahlanong le livaerase ho ka koetlisa sesole sa 'mele ho lemoha livaerase le ho kenya li-immunoglobulins (joalo ka li-antibodies tsa IgG le IgA) ho sireletsa khahlanong le tšoaetso ea baktheria le vaerase.Ha livaerase li kena 'meleng nakong e tlang, liente li ka lemoha le ho bolaea livaerase.Meento e ka boela ea susumetsa sesole sa 'mele le ho theha mohopolo o lumellanang oa 'mele oa ho itšireletsa mafung.Ha livaerase li kena 'meleng nakong e tlang, liente li ka lemoha kapele le ho felisa likokoana-hloko.

Ho ka bonoa ho sena hore sepheo sa ente e boetse ke ho thibela tlhaselo ea lintlha tsa pathogenic ka qi e lekaneng ea bophelo bo botle ka hare ho 'mele e le ho fumana tšireletso e khethehileng ea antiviral.Ganoderma lucidumpolysaccharide e le 'ngoe e ka ntlafatsa ts'ireletso ea 'mele e sa tsitsang hammoho le ts'ireletso e khethehileng ea "humoral" le ts'ireletso ea lisele.Motsoako oaGanoderma lucidum'me ente (antigen) e na le ts'ebetso ea motlatsi, e ka ntlafatsang immunogenicity ea antigen le ho ntlafatsa phello ea ente ea kokoana-hloko.

Sehloohong sa "Adjuvant properties ofGanoderma lucidumpolysaccharides - ho matlafatsa phello ea liente tsa kokoana-hloko" tokollong ea 92 ea"Ganoderm"aka 2021, ke tsebisitse ka botlalo seoGanoderma lucidumli-polysaccharides tse ntšitsoeng le ho hloekisoa ho tsonaGanoderma lucidum'mele ea fruiting e ka ntlafatsa liphello tsa liente tsa porcine circovirus, liente tsa kokoana-hloko ea likolobe le liente tsa kokoana-hloko ea lefu la Newcastle, ho khothalletsa tlhahiso ea li-antibodies tse khethehileng le li-cytokine tsa' mele tse kang interferon-γ, ho fokotsa matšoao a bakoang ke tlhaselo ea kokoana-hloko ho liphoofolo tsa liteko le ho fokotsa ho shoa.Lithuto tsena li fana ka motheo oa lipatlisiso le tšebeliso eaGanoderma lucidumho ntlafatsa phello ea ente e ncha ea coronavirus.

“Ganoderma lucidum+ ente” e ka ntlafatsa tšireletso. 

Kokoana-hloko ea Omicron e na le pathogenicity e tlase le sekhahla sa lefu le tlase, empa e tšoaetsanoa haholo.Kamora hore taolo ea lefu la seoa la "coronavirus" e tlosoe, malapa a mangata kapa likarolo li ile tsa etsa liteko tsa hore li na le nucleic acid kapa tlhahlobo e potlakileng ea antigen.

Ka hona, mokhoa oa bohlokoa ka ho fetisisa oa thibelo bakeng sa ba sa kang ba fetoha hantle ke ho "matlafatsa qi e phetseng hantle le ho felisa pathogen", e leng ho matlafatsa ho itšireletsa mafung ho hanyetsa tšoaetso ea kokoana-hloko.Ganoderma lucidumke e 'ngoe ea likhetho tse kholo tsa ho matlafatsa sesole sa 'mele.KaKhanodermatšireletso e kopantsoeng le ente, u ka ba le monyetla oa ho baleha.

Qetellong, ke tšepa ka tieo seoGanoderma lucidume matlafatsang qi e phetseng hantle le ho felisa likokoana-hloko e ka sebelisoa ho thibela le ho laola seoa sena, ho hlōla likokoana-hloko, le ho sireletsa libōpuoa tsohle tse phelang.

Tlhaloso: 1. Jia-Tsrong Jan, et al.Ho tsebahatsa litlama tse seng li ntse li le teng le meriana ea litlama e le li-inhibitors tsa ts'oaetso ea SARS-CoV-2.Proc Natl Acad Sci USA.2021;118(5): e2021579118.doi: 10.1073/ pnas.2021579118.

Ka bokhutšoaneKenyelletso ea Moprofesa Zhi-binLen

O inehetse thutong eaKhanodermahoo e ka bang halofo ea lekholo la lilemo 'me ke pula-maliboho thutong ea Ganoderma Chaena.

O sebelitse ka tatellano e le motlatsi oa mopresidente oa Univesithi ea Bongaka ea Beijing, motlatsi oa motlatsi oa Sekolo sa Meriana ea Motheo ea Univesithi ea Bongaka ea Beijing, motsamaisi oa Setsi sa Meriana ea Motheo le motsamaisi oa Lefapha la Pharmacology la Univesithi ea Bongaka ea Beijing.Hona joale ke moprofesa Lefapheng la Pharmacology, Sekolo sa Meriana ea Motheo ea Univesithi ea Bongaka ea Beijing.

Ho tloha 1983 ho isa 1984, e ne e le setsebi sa ketelo Setsing sa Lipatlisiso sa Meriana ea WHO Univesithing ea Illinois e Chicago, USA, le moprofesa ea etileng Univesithing ea Hong Kong ho tloha 2000 ho isa 2002. Ho tloha 2006, e bile mohlomphehi. moprofesa oa Perm State Pharmaceutical Academy Russia.

Ho tloha ka 1970, o sebelisitse mekhoa ea morao-rao ea saense ho ithuta liphello tsa pharmacological le mekhoa eaKhanodermale metsoako ea eona e sebetsang 'me e phatlalalitse lipampiri tsa lipatlisiso tse fetang 100 ka Ganoderma.

Ka 2014 le 2019, o kenyelelitsoe lenaneng la Bafuputsi ba Machaena ba Boletsoeng ka ho Fetisisa le hatisitsoeng ke Elsevier ka lilemo tse tšeletseng tse latellanang.

Ke eena mongoli oa palo eaKhanodermae sebetsa joalo ka "Lipatlisiso tsa Kajeno ka Ganoderma" (likhatiso tsa 1-4), "Lingzhi From Mystery to Science" (1-3 edition), "Adjuvant Treatment of Tumors with Lingzhi e matlafatsang bophelo bo botle ba qi le ho felisa likokoana-hloko", "Bua ka Ganoderma ” le “Ganoderma le Bophelo bo Botle”.