◎ Chinyorwa ichi chakatanga kuburitswa mumutauro wechiChinese muChikamu 96 che“Ganoderma” (Zvita 2022), uye yakatanga kuburitswa muchiChinese chakareruka pa “ganodermanews.com” (Ndira 2023), uye yave kudhindwa pano nemvumo yemunyori.

Muchinyorwa "Nheyo yeReishikudzivirira furuwenza ─ Yakakwana hutano qi mukati memuviri ichadzivirira kupinda kwezvinhu zvepathogenic "mune 46th nyaya ye"Ganoderma"mu2009, ndakataura kuti dzidziso yemishonga yechinyakare yeChinese inotenda kuti hutano uye chirwere ndechenyika dzakasiyana dze "kupesana pakati pehutano uye pathogenic qi".Pakati pavo, iyo "hutano qi" inoreva kugona kwemuviri wemunhu kurwisa zvirwere, uye "pathogenic qi" inowanzoreva mavhairasi uye mabhakitiriya anopinda mumuviri wemunhu kana mamota anobuda mumuviri.

Izvi zvinoreva kuti, munhu ane hutano hwakanaka nokuti yakakwana yehutano qi mukati memuviri inodzivirira kupinda kwezvinhu zvepathogenic, kureva kuti, muviri wemunhu une simba rakasimba rekudzivisa zvirwere, izvo hazvirevi kuti hapana pathogenic qi. mumuviri asi zvinoreva kuti pathogenic qi mumuviri haigoni kukurira hutano qi;munhu ari mumamiriro ekurwara nokuti pathogenic zvinhu zvinopinda mumuviri usina kukwana muhutano qi, ndiko kuti, kushomeka kwehutano qi kunoderedza kurwisa kwechirwere chemuviri, uye kuunganidzwa kwezvinhu zvinokonzera zvirwere mumuviri zvinotungamirira kuchirwere.Nzira yakakodzera yekurapa ndeyekubvisa zvachose pathogenic zvinhu.Nekudaro, kusvika parizvino, hapana mushonga wekuMadokero kana wechinyakare mushonga weChinese unogona kubvisa zvachose zvimwe pathogenic zvinhu.

Hazvisi izvo here neanhasi novel coronavirus hutachiona?Nekuda kwekushaikwa kwemishonga inorwisa mavhairasi chaiwo, hapana mushonga wekumadokero kana wechinyakare mushonga weChinese unogona kuuraya hutachiona.Chikonzero nei vanhu vane utachiona vanogona kupora ndechekuvimba nekusimbisa kudzivirirwa kwemuviri (healthy qi) pahwaro hwechiratidzo chekurapa (kurerutsira kwezviratidzo zvisingafadzi) pakupedzisira kubvisa hutachiona (pathogenic qi).

Simba rekudzivirira zvirwere rinoita kuti zviome kuti mavhairasi akonzere zvirwere. 

Iyo novel coronavirus (SARS-CoV-2) yatapurira nekuparadza nyika kwemakore matatu.Mukupera kwa2022, vanhu vanodarika 600 miriyoni vabatwa nechirwere ichi uye vanhu vanopfuura mamirioni matanhatu vakafa.Parizvino, maOmicron akasiyana eiyo novel coronavirus achiri kupararira zvakanyanya pasirese.Kunyangwe iwo pathogenicity uye mwero wekufa zvakaderedzwa zvese, inotapurirana zvakanyanya uye huwandu hwayo hwehutachiona hwakakwira zvakanyanya.

Mishonga inorwisa mavhairasi iripo haigone kuuraya mavhairasi chaiwo, asi inogona kungotadzisa kuwanda kwehutachiona.Kunze kwemaitiro ekudzivirira ekudzivirira akadai sekupfeka masiki, kutarisisa hutsanana hwemaoko, kuchengetedza kushamwaridzana, uye kudzivirira kuungana, chinonyanya kukosha hachisi chimwe chinhu kunze kwe "kusimbisa hutano qi".

Kudzivirirwa (Immunity) zvinoreva kugona kwe immune system yemuviri kuramba uye kubvisa kupinda kwezvirwere zvakaita sebhakitiriya nemavhairasi, kubvisa kuchembera, kufa kana kuchinja maseru mumuviri uye zvinhu zvinokonzeresa kusawirirana, kuchengetedza kugadzikana kwenzvimbo yemukati yemuviri uye. chengetedza muviri wakanaka.

Zvinhu zvakawanda zvakadai sekushushikana mupfungwa, kufunganya, kushanda zvakapfurikidza, kushaya zvokudya zvinovaka muviri, kutadza kurara, kusaita maekisesaizi, kuchembera, zvirwere uye zvinodhaka zvinogona kukanganisa kudzivirirwa kwemuviri uye zvinogona kukonzera kusashanda zvakanaka kwezvirwere zvemuviri kana kuti immune system.

Munguva yedenda, vamwe vanhu vaive nehukama hwepedyo nevanhu vane hutachiona hwekoronavirus havana kurwara uye vakava asymptomatic kesi;vamwe vanhu vakarwara asi vaine zviratidzo zvishoma.

Chikonzero nei vanhu ava vasina zviratidzo kana kuti vane zviratidzo zvakapfava ndezvekuti kudzivirira kwakasimba kwemuviri (healthy qi) kunodzvanya hutachiona (pathogenic qi).Kana pane hutano hwakakwana qi mumuviri, pathogenic zvinhu hazvina nzira yekupinda nayo mumuviri.

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Schematic diagraph yeReishi inosimbisa hutano qi uye kubvisa hutachiona

Reishiinowedzera kudzivirirwa uye inodzivisa hutachiona hwehutachiona.

Reishiine immune-boosting effect.Chekutanga pane zvese, Reishi inogona kukwidziridza iyo isiri-yakananga immune immune yemuviri, kusanganisira kukurudzira kukura, kusiyanisa uye kushanda kwemasero edendritic, kuwedzera basa rekuuraya re mononuclear macrophages uye masero anouraya echisikigo, uye anogona kubvisa zvakananga mavhairasi anopinda.

Chechipiri,Reishiinowedzera mabasa ehumoral immunity uye masero ekudzivirira akadai sekusimudzira kuwanda kwemasero eB, kukurudzira kugadzirwa kweimmunoglobulin (antibody) IgM neIgG, kukurudzira kuwanda kwemasero eT, kuwedzera basa rekuuraya cytotoxic T masero (CTL), uye kukurudzira kugadzirwa kwe cytokines se interleukin-1 (IL-1), interleukin-2 (IL-2) uye interferon-gamma (IFN-gamma).

Zvidzidzo zvakaratidza kuti Reishi anogona kuvharidzira kupukunyuka kwemuviri webundu maseru, asi kana iine mhedzisiro yakafanana pakupukunyuka kwehutachiona hwehutachiona inoramba ichiongororwa.Nekudaro, kune immune hypofunction inokonzerwa nezvikonzero zvakasiyana sekushushikana kwepfungwa, kusagadzikana, kushanda zvakanyanya, kuchembera, chirwere uye zvinodhaka,Reishiyakaratidza kubatsira kudzorera zvakajairika immune system.

Iyo immune-inosimudzira mhedzisiro yeReishi inopa hwaro hwekufungidzira hwekudzivirira kwayo hutachiona hwekoronavirus.

Reishiinonyaradza mweya, inopikisa kushushikana uye inowedzera kudzivirirwa.

Munguva yeCOVID-19 denda, vamwe vanhu vakasangana nekutya, kushushikana, kusagadzikana, kusagadzikana kwekurara, uye kunyangwe kushungurudzika nekuda kwekunetsekana kwepfungwa kunokonzerwa neCCIDID-19 kutapukirwa kana denda rekudzivirira nekudzora matanho, zvese izvo zvinokanganisa kusadzivirirwa.

Muchinyorwa chino "Kuedza kweMhuka uye Kuedza kwevanhu kweGanoderma LucidumAgainst Stress-Induced Immune Function Suppression” muchikamu chechi63 cheGanodermamuna 2014, Ndakataura pamusoro pharmacological kuedza kutiGanoderma lucidumyakavandudza immune system yemakonzo anokonzerwa nekushushikana.Iri bepa rinoratidza kuti kushushikana kwemuviri uye kwepfungwa kunoburitswa nekudzidziswa kwepamusoro-soro kunogona kudzvanya kusashanda kwemuviri kwevatambi, asi Ganoderma lucidum inogona kuvandudza immune system.

Izvi zvinokonzeresa zvine chekuita neiyo immune-yekusimudzira uye inonyaradza mweya maficha eReishi.Mune rimwe izwi, Reishi anobatsira kuderedza kushushikana kwepfungwa nemhedzisiro yayo senge sedative hypnosis, anti-kufunganya, uye anti-depression.Naizvozvo, hazvina kuoma kufungidzira kuti kuita kwemweya-kunyaradza kwaReishi kunogona kuderedza kushushikana kwepfungwa kunokonzerwa neCOVID-19 denda uye kuwedzera kusadzivirirwa.

Ganoderma lucidumzvakare ine anti-novel coronavirus athari.

Ganoderma luciduminonyanyozivikanwa nekuda kweiyo antiviral properties.Munguva yedenda, vanhu vanonyanya kunetseka pamusoro pekutiGanoderma lucidumine anti-novel coronavirus (SARS-Cov-2) mhedzisiro.

Tsvagiridzo yakaitwa nenyanzvi dzeAcademia Sinica, Taiwan yakaburitswa mu "Proceedings of the National Academy of Sciences" Muna 2021 yakaratidza izvozvo.Ganoderma lucidumpolysaccharide (RF3) ine pachena anti-novel coronavirus mhedzisiro mu vivo uye in vitro antiviral bvunzo, uye haina chepfu.

Zvidzidzo zvakaratidza kuti RF3 (2 μg/ml) ine yakakosha antiviral mhedzisiro paSARS-Cov-2 yakasimwa mu vitro, uye ichine inhibitory chiitiko kana yakaderedzwa kusvika ka1280, asi haina chepfu kune hutachiona-host Vero E6. masero.Oral administration yeGanoderma lucidumpolysaccharide RF3 (pamwero wezuva nezuva we30 mg/kg) inogona kuderedza zvakanyanya huwandu hwehutachiwana (zviri mukati) mumapapu ema hamster ane hutachiona hweSARS-Cov-2, asi huremu hwemhuka dzekuyedza hahudzike, zvichiratidza kutiGanoderma lucidumpolysaccharide haina chepfu (sezvinoratidzwa mumufananidzo uri pazasi) [1].

Iyo anti-novel coronavirus maitiro ezvataurwa pamusoro apaGanoderma lucidumpolysaccharides mu vivo uye in vitro inopa hwaro hwekufungidzira hwe "kubvisa pathogenic zvinhu" kudzivirira kwayo hutachiona hwekoronavirus.

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The experimental results ofGanoderma lucidumpolysaccharides kurwisa iyo novel coronavirus mu vivo uye in vitro

Ganoderma luciduminowedzera kushanda kwehutachiona hwekudzivirira.

Mishonga yehutachiona gadziriro yeautoimmune inogadzirwa nekudzikisira, kusashanda kana kushandura mavhairasi kana zvikamu zvawo kudzivirira kutapukirwa nehutachiona.

Mushonga unochengeta hunhu hwehutachiona kana zvikamu zvahwo kuti ukurudzire immune system yemuviri.Kudzivirira mavhairasi kunogona kudzidzisa immune system kuti ione mavhairasi uye kukurudzira immunoglobulins (senge IgG neIgA antibodies) kudzivirira kubva kuhutachiona nehutachiona.Kana mavhairasi apinda mumuviri mune ramangwana, majekiseni anogona kuziva nekuuraya mavhairasi.Majekiseni anogona zvakare kukurudzira kusadzivirirwa kwemasero uye kuumba inowirirana immune ndangariro.Kana mavhairasi achipinda mumuviri mune ramangwana, majekiseni anogona kukurumidza kuona uye kubvisa mavhairasi.

Zvinogona kuonekwa kubva pane izvi kuti chinangwa chekudzivirira ndechekudzivirira kupinda kwezvinhu zvepathogenic nehuwandu hune hutano qi mukati memuviri kuitira kuti uwane humwe hutachiwana hwehutachiona.Ganoderma lucidumpolysaccharide yega inogona kukwidziridza kudzivirirwa kwemuviri kusiri-chaiyo pamwe chete nehutachiona hwehumoral uye kusadzivirirwa kwemasero.Kusanganiswa kweGanoderma lucidumuye vaccine (antigen) ine basa re adjuvant, iyo inogona kuwedzera immunogenicity ye antigen uye kuwedzera mhedzisiro yehutachiona hwekudzivirira.

Muchinyorwa "Adjuvant properties yeGanoderma lucidumpolysaccharides - kuwedzera mhedzisiro yehutachiona hwehutachiona" muchikamu che92 cheGanodermamuna 2021, ndakazivisa zvakadzama izvoGanoderma lucidumpolysaccharides yakabviswa uye yakacheneswa kubvaGanoderma lucidumMitumbi inobereka michero inogona kuwedzera migumisiro yeporcine circovirus vaccines, swine fever virus vaccines uye huku Newcastle chirwere chevhavha yehutachiona, inosimudzira kugadzirwa kweakananga antibodies uye immune cytokines senge interferon-γ, kuderedza zviratidzo zvinokonzerwa nehutachiona kurwisa mhuka dzekuedza uye kuderedza kufa.Zvidzidzo izvi zvinopa hwaro hwekutsvaga nekushandiswa kweGanoderma lucidumkuwedzera mashandiro eiyo novel coronavirus vaccine.

Ganoderma lucidum+ vaccine” inogona kuvandudza dziviriro. 

Omicron virus ine yakaderera pathogenicity uye yakaderera kesi yekufa mwero, asi inopararira zvakanyanya.Mushure meiyo novel coronavirus denda kudzora kwasimudzwa, mhuri zhinji kana mayunitsi akaongororwa ane hutachiona nucleic acid kana antigen nekukurumidza kuongorora.

Nokudaro, iyo inonyanya kukosha yekudzivirira chiyero kune avo vasina kutendeuka ndeye "kusimbisa hutano qi uye kubvisa pathogen", kureva kuwedzera hutachiona hwekudzivirira hutachiona hwehutachiona.Ganoderma lucidumndeimwe yeakanakisa sarudzo dzekuwedzera immune immune.WithGanodermadziviriro yakasanganiswa nejekiseni, unogona kuwana mukana wekupukunyuka.

Pakupedzisira, ndinovimba nomwoyo wose izvozvoGanoderma lucidumiyo inosimbisa hutano qi uye inobvisa hutachiona inogona kushandiswa kudzivirira uye kudzora denda, kukunda hutachiona, uye kuchengetedza zvipenyu zvese.

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Chirevo: 1. Jia-Tsrong Jan, et al.Kuzivikanwa kwemishonga iripo uye mishonga yemakwenzi sema inhibitors ehutachiona hweSARS-CoV-2.Proc Natl Acad Sci USA.2021;118(5): e2021579118.doi: 10.1073/ pnas.2021579118.

MuchidimbuNhanganyaya yaProfessor Zhi-binLin

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Akazvipira pakudzidza kweGanodermakweanoda kusvika hafu yezana ramakore uye ari piyona mukudzidza kweGanoderma muChina.

Akazoshanda semutevedzeri wemutungamiri weBeijing Medical University, mutevedzeri wemukuru weChikoro cheBasic Medicine cheBeijing Medical University, director weInstitute of Basic Medicine uye director weDhipatimendi reParmacology reBeijing Medical University.Parizvino purofesa muDhipatimendi rePharmacology, Chikoro cheBasic Medicine cheBeijing Medical University.

Kubva 1983 kusvika 1984, akange ari nyanzvi yekushanya paWHO Traditional Medicine Research Center paUniversity of Illinois muChicago, USA, uye ari purofesa anoshanya paUniversity yeHong Kong kubva 2000 kusvika 2002. Kubva 2006, anga ari anoremekedzwa. purofesa paPerm State Pharmaceutical Academy muRussia.

Kubva 1970, akashandisa nzira dzemazuva ano sci-tech kudzidza maitiro ezvemishonga uye maitiro eGanodermauye zvayakaita zvinosanganisa uye yakaburitsa anopfuura zana mapepa ekutsvagisa paGanoderma.

Muna 2014 na2019, akaverengerwa mune Yakanyanya Cited Chinese Vatsvagiri runyorwa rwakaburitswa naElsevier kwemakore matanhatu akateedzana.

Ndiye munyori wehuwandu hweGanodermainoshanda se "Modern Research on Ganoderma" (1-4 editions), "Lingzhi From Mystery to Science" (1-3 editions), "Adjuvant Treatment of Tumors with Lingzhi inosimbisa hutano qi uye inobvisa utachiona", "Taura nezveGanoderma ” uye “Ganoderma uye Utano”.


Nguva yekutumira: Mar-02-2023

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