◎ Maqaalkan waxaa markii ugu horreysay lagu daabacay Shiinaha dhaqameed ee Tirsiga 96 ee "Ganoderma"(Diseembar 2022), waxaana markii ugu horreysay lagu daabacay Shiinaha la fududeeyay "ganodermanews.com" (Janaayo 2023), oo hadda halkan lagu daabacay iyadoo oggolaansho laga haysto qoraaga.

Maqaalka "SaldhiggaReishisi looga hortago ifiladaGanoderma"2009, waxaan xusay in aragtida daawada dhaqameed ee Shiinaha ay aaminsan tahay in caafimaadka iyo cudurku ay ka tirsan yihiin gobollada kala duwan ee "isku dhaca u dhexeeya caafimaadka iyo cudur-sidaha qi".Waxa ka mid ah, “qi caafimaad qaba” waxa ay tilmaamaysaa awoodda jidhka bini’aadamka u leeyahay iska caabinta cudurrada, iyo “pathogenic qi” guud ahaan waxa loola jeedaa fayrasyada iyo bakteeriyada ku soo duusha jidhka bini’aadamka ama burooyinka ka soo baxa jidhka.

Taasi waa in la yidhaahdo, qofku waa xaalad caafimaad leh sababtoo ah ku filan oo caafimaad leh oo ku filan gudaha jidhka ayaa ka hortagaya duulaanka arrimaha pathogenic, taas oo ah, jidhka bini'aadamka wuxuu leeyahay awood xooggan oo uu iskaga caabiyo cudurrada, taas macnaheedu maaha in aysan jirin wax cudur-sidaha ah. jidhka dhexdiisa laakiin waxa ay ka dhigan tahay in cudurka pathogenic ee jidhku aanu ka adkaan karin qi caafimaadka qaba;Qofku waxa uu ku sugan yahay xaalad jirro,sababtoo ah waxa keena cudur-sidaha jidhka ku soo duulaya oo ay ka liidato qi caafimaad qabta,taas oo ah, yaraanta qi caafimaad qabta waxa ay daciifisaa iska caabbinta cudurrada jidhka,waxana ku ururista waxyaalaha sababa caabuqa ee jidhka ku keena cuduro.Habka ugu habboon ee daaweyntu waa in gebi ahaanba la tirtiro waxyaabaha keena cudurka.Si kastaba ha noqotee, ilaa hadda, dawada reer galbeedka ama daawada dhaqameed ee Shiinaha si buuxda uma baabi'in karto qaar ka mid ah arrimaha cudurka.

Miyaanay taasi ahayn infekshanka coronavirus-ka cusub ee maanta?Sababtoo ah la'aanta dawooyin gaar ah oo ka hortagga fayraska, daawooyinka reer galbeedka ama daawada dhaqameed ee Shiinaha si fiican uma dili karaan fayraska.Sababta ay dadka cudurka qaba u soo kaban karaan waa inay ku tiirsanaadaan xoojinta difaaca jirka (qi caafimaad qaba) iyadoo lagu salaynayo daawaynta calaamadaha (calamadaha aan fiicnayn) si ay ugu dambeyntii u nadiifiyaan fayraska (pathogenic qi).

Nidaam difaac oo xoog leh ayaa ku adkeynaya fayrasyadu inay cudurro keenaan. 

Fayraska novel coronavirus (SARS-CoV-2) wuxuu haleelay oo dunidoo dhan baabi'iyay muddo 3 sano ah.Dhamaadka 2022, in ka badan 600 milyan oo qof ayaa cudurka qaaday in ka badan 6 milyan oo qofna way dhinteen.Waqtigan xaadirka ah, noocyada Omicron ee novel coronavirus ayaa wali si ba'an ugu faafaya adduunka oo dhan.In kasta oo heerka cudurkooda iyo dhimashadooda ay labaduba hoos u dhaceen, aad bay u faafaan heerka caabuqa waa mid aad u sarreeya.

Daawooyinka ka hortagga fayraska ee jira ma dili karaan fayrasyo ​​gaar ah, laakiin waxay joojin karaan oo keliya faafidda fayraska.Marka laga reebo tallaabooyinka ka hortagga caadiga ah sida xirashada maaskaro, fiiro gaar ah u yeelashada nadaafadda gacmaha, ilaalinta kala fogaanshaha bulshada, iyo ka fogaanshaha isu imaatinka, waxa ugu muhiimsan waa wax ka badan "xoojinta qi caafimaad qabta".

difaacu waxa loola jeedaa awooda habka difaaca jidhku u leeyahay in uu iska caabiyo oo uu meesha ka saaro duulaanka cudurada sida bakteeriyada iyo fayrasyada, ka saara gabowga, unugyada dhintay ama isbedelay ee jidhka iyo walxaha sababa falcelinta xasaasiyadda, ilaalinta xasiloonida deegaanka gudaha ee jidhka jidhka ku ilaali.

Waxyaabo badan oo ay ka mid yihiin walbahaarka maskaxda, walbahaarka, shaqada xad dhaafka ah, nafaqo-xumada, hurdo la'aanta, jimicsi la'aanta, gabowga, cudurrada iyo daroogooyinka ayaa saameyn ku yeelan kara difaaca jirka waxayna sababi karaan difaaca jirka oo yaraada ama difaaca jirka oo yaraada.

Intii uu cudurku socday, dadka qaarkood oo xiriir dhow la lahaa dadka uu ku dhacay cudurka 'coronavirus' novel ma aysan jiran oo waxay noqdeen kiisas asymptomatic ah;dadka qaar ayaa bukooday laakiin waxay lahaayeen astaamo fudud.

Sababta ay dadkani u yihiin asymptomatic ama ay leeyihiin calaamado khafiif ah ayaa ah in difaaca xooggan ee jirku (qi caafimaad qaba) uu xakameeyo fayraska (pathogenic qi).Marka ay jirto qi ku filan oo caafimaad qabta oo jidhka ku jirta, arrimaha caabuqa keena ma laha hab ay ku duulaan jidhka.

Jaantuska jaantuska ee Reishi xoojinta qi caafimaadka qabta iyo baabi'inta cudurada

ReishiWaxay kordhisaa difaaca waxayna joojisaa caabuqyada fayraska.

Reishiwaxay leedahay saamayn difaac-kordhinta.Ugu horreyntii, Reishi waxay kor u qaadi kartaa shaqada difaaca ee aan gaarka ahayn ee jirka, oo ay ku jiraan kor u qaadista korriinka, kala duwanaanta iyo shaqada unugyada dendritic, kor u qaadista waxqabadka dilka ee macrophages mononuclear iyo unugyada dilaaga dabiiciga ah, waxayna si toos ah u baabi'in kartaa fayraska soo duulay.

Marka labaad,ReishiWaxay wanaajisaa hawlaha difaaca kaftanka iyo difaaca unugga sida kor u qaadida badinta unugyada B, kor u qaadida soosaarka immunoglobulin (antibody) IgM iyo IgG, kor u qaadida faafinta unugyada T, kor u qaadida waxqabadka dilka unugyada cytotoxic T unugyada (CTL), iyo kor u qaadista wax soo saarka cytokines sida interleukin-1 (IL-1), interleukin-2 (IL-2) iyo interferon-gamma (IFN-gamma).

Daraasaduhu waxay muujiyeen in Reishi uu joojin karo baxsashada difaaca ee unugyada burooyinka, laakiin haddii ay saameyn la mid ah ku leedahay badbaadada difaaca ee fayraska ayaa weli ah in la sii darso.Si kastaba ha ahaatee, hoos u dhac ku yimaada difaaca jirka oo ay sababaan sababo kala duwan sida walbahaarka maskaxda, welwelka, shaqada dheeraadka ah, gabowga, cudurada iyo daroogooyinka,Reishiayaa la caddeeyey in ay gacan ka geysato soo celinta shaqadii caadiga ahayd ee difaaca.

Saamaynta difaaca jirka ee Reishi waxay bixisaa aasaas aragtiyeed oo loogu talagalay ka hortagga caabuqa coronavirus.

Reishiwaxay dejisaa ruuxa, waxay ka hortagtaa walbahaarka waxayna xoojisaa difaaca.

Intii lagu jiray masiibada COVID-19, dadka qaar waxay la kulmeen cabsi, kacsanaan, walaac, hurdo la'aan, iyo xitaa niyad-jabka kadeedka maskaxeed ee uu sababay caabuqa COVID-19 ama ka-hortagga iyo xakamaynta faafidda, kuwaas oo dhammaantood saamayn doona difaaca.

Maqaalka "Tijaabada Xoolaha iyo Tijaabada Aadanaha eeGanoderma LucidumKa-hortagga Cadaadiska Ka-hortagga Shaqada Difaaca ee Cadaadiska" ee cadadka 63aad eeGanoderma2014, waxaan ka hadlay tijaabooyinka dawooyinkaGanoderma lucidumwaxay wanaajisay shaqada difaaca ee jiirarka oo ay sababtay diiqada.Warqadani waxay tilmaamaysaa in culeyska jireed iyo maskaxeed ee uu soo saaro tababbarka xoogga badan uu xakameyn karo shaqada difaaca ee ciyaartoyda, laakiin Ganoderma lucidum waxay hagaajin kartaa shaqada difaaca.

Saamayntan waxay la xiriirtaa kor u qaadista difaaca jirka iyo astaamaha xasilinta ruuxaReishi.Si kale haddii loo dhigo, Reishi waxay ka caawisaa yaraynta diiqada maskaxda ee saameynteeda sida suuxinta hypnosis, ka-hortagga walaaca, iyo niyad-jabka.Sidaa darteed, ma adka in la qiyaaso in waxtarka xasilloonida ruuxa ee Reishi ay yarayn karto walbahaarka maskaxeed ee uu keeno masiibada COVID-19 ayna kor u qaaddo difaaca.

Ganoderma lucidumsidoo kale waxay leedahay saamayn ka hortagta novel coronavirus.

Ganoderma lucidumayaa si fiican loogu yaqaanaa sifooyinka fayraska.Inta lagu jiro cudurka faafa, dadku waxay aad uga walaacsan yihiin iyo in kaleGanoderma lucidumwaxay leedahay saamayn ka-hortagga novel coronavirus (SARS-Cov-2).

Cilmi-baaris ay sameeyeen aqoonyahanno ka socda Akadeemiyada Sinica, Taiwan oo lagu daabacay "Talaabada Akadeemiyada Qaranka ee Sayniska" 2021 waxay caddeeyeen inGanoderma lucidumpolysaccharide (RF3) waxay leedahay saameyn cad oo ka hortagga-novel coronavirus gudaha vivo iyo in vitro baaritaannada fayraska ka hortagga, oo aan sun ahayn.

Daraasaduhu waxay muujiyeen in RF3 (2 μg / ml) ay saameyn weyn ku leedahay fayraska SARS-Cov-2 ee lagu beeray vitro, oo ay wali leedahay waxqabadyo xannibaad ah marka lagu qaso 1280 jeer, laakiin wax sun ah uma laha fayraska- martida loo yahay ee Vero E6. unugyo.Maamulka afka eeGanoderma lucidumpolysaccharide RF3 (qiyaas maalinle ah oo ah 30 mg/kg) waxay si weyn u yarayn kartaa culayska fayraska (content) ee sambabada hamsters-ka ee uu ku dhacay fayraska SARS-Cov-2, laakiin miisaanka xayawaanka tijaabada ahi ma yaraado, taas oo muujinaysa inGanoderma lucidumpolysaccharides ma aha sun (sida ku cad sawirka hoose) [1].

Saamaynta ka-hortagga novel coronavirus ee kuwa aan kor ku soo sheegnayGanoderma lucidumpolysaccharides in vivo iyo in vitro waxay bixisaa aasaas aragtiyeed oo loogu talagalay "ciribtirka arrimaha pathogenic" ee ka hortagga caabuqa cusub ee coronavirus.

Natiijooyinka tijaabada ah eeGanoderma lucidumpolysaccharides ka dhanka ah novel coronavirus in vivo iyo in vitro

Ganoderma lucidumwaxay kordhisaa saamaynta tallaalka fayraska.

Tallaalada fayrasku waa diyaargarow isdifaac ah oo lagu sameeyo si macmal ah loo yareeyo, kicinta ama wax ka beddelka fayrasyada ama qaybahooda si looga hortago caabuqyada fayraska.

Tallaalku waxa uu hayaa sifooyinka fayraska ama qaybihiisa si uu u kiciyo habka difaaca jidhka.Tallaalka ka dhanka ah fayrasku wuxuu tababari karaa habka difaaca si uu u aqoonsado fayraska oo uu keeno immunoglobulins (sida IgG iyo IgA antibodies) si looga ilaaliyo caabuqyada bakteeriyada iyo fayraska.Marka fayrasyadu mustaqbalka soo galaan jidhka, tallaaladu waxay aqoonsan karaan oo dili karaan fayraska.Talaalku waxa kale oo ay kicin karaan difaaca unugga oo ay sameeyaan xasuus difaac oo u dhiganta.Marka fayrasyadu mustaqbalka soo galaan jidhka, tallaaladu si dhakhso ah ayey u aqoonsan karaan oo u baabi'in karaan fayraska.

Waxaa laga arki karaa tan in ujeedada tallaalku ay sidoo kale tahay in laga hortago duulaanka arrimaha pathogenic by qi ku filan oo caafimaad qaba gudaha jirka si loo helo difaac gaar ah oo fayraska ah.Ganoderma lucidumpolysaccharides oo keliya ayaa kor u qaadi karta difaaca jirka ee aan gaarka ahayn iyo sidoo kale difaac kaftan gaar ah iyo difaaca unugyada.Isku darkaGanoderma lucidumiyo tallaalka (antigen) wuxuu leeyahay shaqada adjuvant, kaas oo kor u qaadi kara difaaca jirka ee antigen iyo kor u qaadida saameynta tallaalka fayraska.

In maqaalka "Adjuvant Properties eeGanoderma lucidumpolysaccharides - kor u qaadida saamaynta tallaalada fayraska" ee cadadka 92aad eeGanoderma2021, waxaan si faahfaahsan u soo bandhigay taasGanoderma lucidumpolysaccharides oo laga soo saaro lagana nadiifiyoGanoderma lucidumMiraha miraha waxay kor u qaadi karaan saamaynta tallaalada circovirus doofaarka, tallaalada fayraska qandhada doofaarka iyo digaaga tallaalada fayraska cudurka Newcastle, waxay kor u qaadaan soo saarista unugyada difaaca gaarka ah iyo cytokines difaaca sida interferon-γ, waxay yareeyaan calaamadaha ay sababaan fayras weerar ku ah xayawaanka tijaabada ah waxayna yareeyaan dhimashada.Daraasadahani waxay aasaas u yihiin cilmi-baarista iyo ku dhaqankaGanoderma lucidumsi kor loogu qaado saamaynta tallaalka coronavirus-ka cusub.

"Ganoderma lucidum+ tallaalka” ayaa wanaajin kara ilaalinta. 

Fayraska Omicron wuxuu leeyahay cudur-gaarsiineed hooseeya iyo heerka dhimashada kiisaska hooseeya, laakiin aad ayuu u faafayaa.Ka dib markii la qaaday xakameynta cudurka faafa ee coronavirus-ka cusub, qoysas badan ama cutubyo ayaa laga helay baaritaanka degdega ah ee nucleic acid ama antigen.

Sidaa darteed, qiyaasta ugu muhiimsan ee ka-hortagga kuwa aan si wanaagsan u soo jeedin waa "xoojinta qi caafimaad qabta iyo baabi'inta cudur-sidaha", taas oo ah in kor loo qaado difaaca si looga hortago caabuqa fayraska.Ganoderma lucidumwaa mid ka mid ah fursadaha ugu weyn ee kor loogu qaado difaaca.lehGanodermailaalinta lagu daray tallaalka, waxaa laga yaabaa inaad fursad u hesho inaad ka baxsato.

Ugu dambeyntii, waxaan si dhab ah u rajeynayaa taasGanoderma lucidumtaas oo xoojisa qi caafimaad qabta oo meesha ka saarta cudur-sidaha waxa loo isticmaali karaa in lagaga hortago oo la xakameeyo faafitaanka, lagana adkaado cudur-sidaha, loona ilaaliyo dhammaan noolaha.

Tixraac: 1. Jia-Tsrong Jan, et al.Aqoonsiga dawooyinka jira iyo dawooyinka dhirta inay yihiin hor-joogayaasha caabuqa SARS-CoV-2.Proc Natl Acad Sci USA.2021;118 (5): e2021579118.doi: 10.1073/ pnas.2021579118.

KoobanHordhaca Professor Zhi-binLin

Waxa uu naftiisa u huray in uu wax bartoGanodermaku dhawaad ​​nus qarni waana hormuudka daraasadda Ganoderma ee Shiinaha.

Waxa uu si isdaba joog ah u noqday gudoomiye ku xigeenka Jaamacadda Caafimaadka ee Beijing, kuxigeenka madaxa Iskuulka Caafimaadka Aasaasiga ah ee Jaamacadda Caafimaadka ee Beijing, Agaasimaha Machadka Daawada Aasaasiga ah iyo Agaasimaha Waaxda Farmashiga ee Jaamacadda Caafimaadka ee Beijing.Hadda waa borofisar ka tirsan Waaxda Farmashiyaha, Dugsiga Daawada aasaasiga ah ee Jaamacadda Caafimaadka ee Beijing.

Laga soo bilaabo 1983 ilaa 1984, wuxuu ahaa aqoonyahan booqasho ku jooga Xarunta Cilmi-baarista Daawada Dhaqanka ee WHO ee Jaamacadda Illinois ee Chicago, USA, iyo borofisar booqday Jaamacadda Hong Kong 2000 ilaa 2002. Ilaa 2006, wuxuu ahaa sharaf. Professor wax ka dhiga Akademiyada Dawooyinka ee Gobolka Perm ee Ruushka.

Tan iyo 1970-kii, waxa uu isticmaalay hababka sci-technology ee casriga ah si uu u barto saamaynta dawooyinka iyo hababkaGanodermaiyo maaddooyinkeeda firfircoon waxayna daabacday in ka badan 100 waraaqo cilmi-baaris ah oo ku saabsan Ganoderma.

2014 iyo 2019, waxaa lagu daray liiska cilmi-baarayaasha Shiinaha ee inta badan la soo xigtay ee uu daabacay Elsevier lix sano oo isku xigta.

Isagu waa qoraaga tiro ka mid ahGanodermaWaxay u shaqeysaa sida "Cilmi-baaris Casri ah oo ku saabsan Ganoderma" (1-4 daabacado), "Lingzhi From Mystery to Science" (1-3 daabacado), "Daawaynta Adjuvant ee Burooyinka leh Lingzhi taas oo xoojisa qi caafimaad leh oo ka takhalusta cudurada", "Ka hadal Ganoderma". "iyo" Ganoderma iyo Caafimaadka".