Mu ngingo “Ingaruka eshatu zamavuriro yaGanoderma lucidummugutezimbere virusi ya hepatite ", twabonye ubushakashatsi bwamavuriro bubigaragazaGanoderma lucidumIrashobora gukoreshwa wenyine cyangwa ifatanije nubuvuzi busanzwe bufasha kandi bwerekana ibimenyetso bifasha abarwayi barwaye hepatite ya virusi kurwanya inflammation na virusi no kugenzura ubudahangarwa bwuzuye.Rero, birashobokaGanoderma lucidumn'imiti ikunze gukoreshwa imiti igabanya ubukana nayo igira uruhare rwuzuzanya?

Mbere yo gucengera muri iyi ngingo, tugomba kumva ko imiti igabanya ubukana idashobora kwica virusi ariko ko ishobora kubuza ikwirakwizwa rya virusi yinjiye muri “selile” kandi ikagabanya umubare w’ikwirakwizwa rya virusi.

Mu yandi magambo, imiti igabanya ubukana bwa virusi nta ngaruka igira kuri virusi zikiri “hanze y’akagari” zishakisha intego zanduza.Bagomba kwishingikiriza ku mbaraga zihuriweho na antibodies zikorwa na sisitemu yumubiri hamwe ningirabuzimafatizo zirimo macrophage kugirango bakureho virusi.

Niyo mpamvu hari umwanya wo gufata imiti igabanya ubukana kandiGanoderma lucidumgukora mu ntoki - kuberaGanoderma lucidumni byiza kugenzura ubudahangarwa bw'umubiri, birashobora gusa kuzuza ibura ry'imiti igabanya ubukana;naGanoderma lucidumIngaruka zo kubuza virusi nazo ni imbaraga nyinshi ku miti igabanya ubukana bwa virusi.

Raporo y’amavuriro yatangajwe, yaba ikoreshwa n’imiti igabanya ubukana nka Lamivudine, Entecavir cyangwa Adefovir mu gihe kirenga umwaka,Ganoderma lucidumntabwo ibangamira efficacy cyangwa itera ingaruka mbi.Ibinyuranye na byo, irashobora gufasha abarwayi ba hepatite B idakira kugera ku ngaruka "zihuse" cyangwa "nziza" zo kurwanya inflammatory na virusi, kugabanya kugaragara kw'ibiyobyabwenge, no kunoza indwara z’ubudahangarwa.Ingaruka yiyi yongeyeho imwe nini cyane kuburyo ntampamvu yo kutayikoresha hamwe.

Imwe mu nyungu za “Ganoderma lucidum+ imiti igabanya ubukana ”ntabwo byoroshye guteza imbere imiti.

Raporo y’ivuriro yasohowe n’ishuri rikuru rya kabiri ry’ubuvuzi rya kaminuza ya Guangzhou y’ubuvuzi bw’Ubushinwa mu 2007, mu barwayi barwaye hepatite B idakira bakiriye 6Ganoderma lucidumcapsules kumunsi yose hamwe garama 1.62 (ihwanye na garama 9 zaGanoderma lucidumimibiri yera) ifatanije nu muti wa lamivudine ya virusi ya virusi mu gihe cyumwaka umwe, bamwe muribo bavuwe n’imiti ifasha kandi yerekana ibimenyetso aho kuyindi miti igabanya ubukana.

Kubera iyo mpamvu, hepatite yorohewe vuba, nta ADN ya virusi yagaragaye mu maraso y’umurwayi (byerekana ko umubare wa virusi wagabanutse ukaba utagisuka mu maraso ava mu mwijima), kandi amahirwe ya e antigen yabuze / ahinduka nabi yari ugereranije hejuru (virusi ntikigaragara cyane).Muri icyo gihe, amahirwe yo kurwanya ihinduka ry’imiti muri gen yagabanutse cyane.

Kubera ko nta mavuriro yabayeho mu gihe cyo kuvura kwose, nta mpinduka mbi zigeze mu mikorere y’amaraso no gupima imikorere yimpyiko, inshuro 2 zimpiswi mu itsinda rya virusi itera virusi kandi ni 1 gusa yo kubabara umutwe byoroheje mu itsinda ryavuwe na Ganoderma, ariko izi zose uko ari 3 bose bashoboye guhita boroherwa, byerekanaga ko kuvuraGanoderma lucidumihujwe n'imiti igabanya ubukana ntabwo ikora neza gusa ahubwo ifite umutekano.

Ganoderma lucidum ntishobora gusa kunoza imikorere yimiti igabanya ubukana bwa virusi ahubwo inaha abarwayi ingaruka zubudahangarwa imiti ya virusi idafite.Raporo y’ubuvuzi yasohowe mu mwaka wa 2016 n’ikigo cya Clinical Laboratory Centre yo mu Mujyi wa Huangshi, mu Ntara ya Hubei yasanze nyuma y’umwaka umwe wo kuvura abarwayi ba hepatite B idakira bafite capsules 6 ya Ganoderma lucidum ikozwe muri Ganoderma lucidum yera imbuto ziva mu mubiri zingana na garama 1.62 (bihwanye na garama 9) ya Ganoderma lucidum yera imbuto) kumunsi hamwe nibiyobyabwenge bya virusi Entecavir, indangagaciro ya hepatite isubira mubisanzwe, virusi iragabanuka, amahirwe yo kwigana virusi aracika intege, kandi selile Th17 zijyanye no gutwika mumaraso nazo ziragabanuka. Virusi ya hepatite B. itera umwijima kuko sisitemu yumubiri igomba kwibasira selile yumwijima kugirango ikureho virusi yihishe muri selile.Iyo intambara hagati ya virusi nubudahangarwa itigeze irangira, sisitemu yumubiri igenda itakaza buhoro buhoro hagati yo guteza umuriro (anti-virusi) no guhagarika umuriro (kurinda selile).Kimwe mu bipimo byihariye ni umusaruro ukabije wa Th17 selile zifasha T selile (Th selile) zitegeka sisitemu yumubiri kurwanya.

Th17 selile zikoreshwa cyane mugutezimbere no kurwanya indwara.Iyo umubare wabo ari munini cyane, bizagabanya irindi tsinda ryingirabuzimafatizo T (TReg) zifite inshingano zo kubuza gucana.Gukoresha hamwe kwa Ganoderma lucidum na Entecavir birashobora kugabanya cyane selile Th17, nta gushidikanya ko bigira uruhare mu kuzamura umwijima w’umwijima - bityo rero umubare w’imanza aho igipimo cya hepatite gisubira mu buzima kizaba kirenze icya Entecavir yakoreshejwe wenyine.

Kubera ko imiti igabanya ubukana ishobora guhagarika virusi gusa kandi ikaba idafite ubushobozi bwo kugenzura ubudahangarwa, kugabanuka kwa Th17 biragaragara ko bifitanye isano na Ganoderma lucidum;kubera ko kugabanuka kwa Th17 kutagira ingaruka ku guhagarika virusi, Ganoderma lucidum ntigomba gukosora selile Th17 gusa ahubwo inatezimbere ubusumbane bw’ubudahangarwa bw’abarwayi ba hepatite B.
Raporo y’amavuriro yasohowe n’ibitaro bya gatandatu by’abaturage bo mu mujyi wa Shaoxing, mu Ntara ya Zhejiang mu mwaka wa 2011 yanagaragaje abarwayi ba hepatite B idakira bavuwe hamwe na ml 100 y’imiti ya Ganoderma lucidum (ikozwe muri garama 50 z’imibiri yera ya Ganoderma na garama 10 z’amatariki atukura n’amazi) ihujwe n'umuti wa virusi Adefovir imyaka ibiri ikurikiranye.Ubu buvuzi ntabwo bugira ingaruka nziza gusa zo kugabanya hepatite cyangwa guhagarika virusi ya hepatite ahubwo binagira ingaruka zo kugenzura ubudahangarwa bw'umubiri, harimo no kongera umubare w'uturemangingo twica kamere, selile T na CD4 + T-selile muri lymphocytes, no kwiyongera kwa CD4 + kugirango yongere igipimo cya CD4 + / CD8 + T-selile, kugirango yegere ubuzima bwiza.

Abarwayi ba hepatite B idakira bakunze kugabanuka muri selile T muri rusange, kugabanuka kwa CD4 + no kwiyongera kwa CD8 + mugihe inzira yindwara igenda yiyongera, bigatuma igabanuka rya CD4 + / CD8 +.CD4 + T ifite selile ya CD4 + ya molekulari hejuru yutugari irimo "umufasha T selile" cyangwa "selile T selile", zishobora gutegeka ingabo zose z'umubiri kurwana (harimo no gutegeka selile B gukora antibodies) no guhuza umuriro mugihe gikwiye. ;na CD8 + T selile zifite ibimenyetso bya CD8 + hejuru ya selile ni "selile T selile" zishobora kwica ubwonko selile zanduye virusi (na kanseri).Amatsinda yombi ya T selile atandukanye na selile T ya primitique, bityo bigira ingaruka kumubare.Iyo virusi ikomeje kwanduza selile, itera umubare munini wa selile T gutandukanya selile T yica (CD8 +), mubisanzwe bigira ingaruka kumubare wa CD4 + ninshingano zayo zo kuyobora no guhuza ibikorwa.Iterambere nk'iryo rizagira ingaruka ku mikorere y’ubudahangarwa bwo kurwanya virusi no kurwanya inflammatory, kandi ryangiza kuvura hepatite B.

Kubwibyo, gukoresha hamwe na Ganoderma lucidum hamwe nibiyobyabwenge bya virusi adefovir dipivoxil birashobora kongera umubare wa selile T na CD4 + muri byo, bityo bikongerera CD4 + / CD8 +, kandi mugihe kimwe byongera gato selile zica zisanzwe zifitiye akamaro akamaro. anti-virusi no kurwanya ibibyimba.Ibi ni ibimenyetso byerekana iterambere ryimikorere yubudahangarwa bw’abarwayi barwaye hepatite B idakira, kandi ingaruka ni nziza cyane kuruta iy'abarwayi bavuwe n'imiti ya virusi yonyine.
 
Byongeye kandi, raporo y’amavuriro yanditse kandi ko nta guhubuka, gastrointestinal reaction, creatine kinase (creatinine) kwiyongera ndetse n’imikorere idasanzwe y’impyiko byagaragaye mu masomo yose mu gihe cyo kuvura, ibyo bikaba bishimangira umutekano wa Ganoderma lucidum mu kuvura virusi itera virusi.Ibintu birwanya virusi na anti-inflammatory bifasha kurinda umwijima gukomera no guhagarikwa buhoro buhoro mugihe cyo gutwika no gusana inshuro nyinshi, bikagaragaza akamaro kabo kubarwayi barwaye hepatite idakira B. Fibrosis yumwijima nintangiriro yumwijima cirrhose.Niba ibipimo bifatika bya fibrosis yumwijima bishobora kugabanuka mugihe cyo kuvura hepatite B, ibi birashobora kandi kuba ikindi kimenyetso cyerekana ko kuvura ari byiza.

Raporo y’amavuriro yatanzwe n’ibitaro bya kane by’abaturage bo mu Mujyi wa Panzhihua, Intara ya Sichuan mu 2013, binyuze mu byumweru 48 (hafi umwaka 1) bivura abarwayi ba hepatite B idakira hamwe na capsules 9 ya Ganoderma lucidum yuzuye garama 2,43 ku munsi (bihwanye na 13.5 g ya Ganoderma lucidum yera imbuto) ifatanije n’imiti igabanya ubukana bwa Adefovir dipivoxil hamwe n’imiti irinda umwijima, ibimenyetso simusiga kandi bifasha, basanze ibipimo by’umwijima by’umurwayi byateye imbere ku buryo bugaragara, kandi ibimenyetso bine biri mu maraso y’umurwayi bijyanye na fiboside y’umwijima na byo byagabanutse bivuye hanze. bisanzwe mubisanzwe cyangwa hafi yubusanzwe.Ibi bintu byagaragaje ko ingaruka zuzuzanya za Ganoderma lucidum n’imiti igabanya ubukana zishobora no kugaragara mu gukumira indwara z’umwijima.

Twabibutsa ko mu barwayi 60 bakiriye imiti ya Ganoderma lucidum na adefovir dipivoxil, abarwayi 3 (5%) nta virusi ya hepatite B yamenyekanye (HBsAg ihinduka ryiza) hanyuma bakora antibodies kuri virusi (Anti-HBs positif positif) nyuma yo ubuvuzi bwarangiye.Ingaruka nkiyi yo kuvura ntabwo iboneka byoroshye ugereranije nintego yuko 1% byabarwayi ba hepatite B bahabwa imiti igabanya ubukana bwa virusi bashobora kwandura antibody mbi buri mwaka.Ganoderma lucidum irashobora kunoza imikorere yimiti igabanya ubukana bwa virusi, nayo yongeye kugaragara.Ganoderma lucidum yera imbuto yumubiri irashobora kugenga ibintu byose byubudahangarwa.Ubudahangarwa bwiza bushobora kwirinda kwandura, indwara zidakira no kongera kubaho.

Raporo enye z’amavuriro zavuzwe haruguru ntizerekana gusa inyungu za Ganoderma lucidum mu gufasha imiti igabanya ubukana bwa virusi ya hepatite B idakira ariko inerekana ko bishoboka gukoresha Ganoderma lucidum n’indi miti igabanya ubukana hamwe.

Capsules ya Ganoderma lucidum na decoction ya Ganoderma lucidum ikoreshwa mubushakashatsi byombi bivoma amazi mumibiri yera imbuto ya Ganoderma lucidum.

Ibikoresho bifatika byabonetse mugukuramo imibiri yimbuto ya Ganoderma lucidum namazi ni polysaccharide harimo peptide ya polysaccharide na glycoproteine, na triterpenoide nkeya.Ibi bikoresho nisoko ikora ya Ganoderma lucidum kugirango igenzure imikorere yumubiri.Ihuriro rya triterpenoide rishobora kubuza umuriro udasanzwe no kubuza kwandura virusi nta gushidikanya ko risobanura byimazeyo ingaruka za bonus ya Ganoderma lucidum mu gufasha imiti igabanya ubukana bwa virusi.

Mubyukuri, urufunguzo rwingenzi mu kuvura indwara za virusi ndetse no kwirinda indwara zitandukanye za virusi ni ubudahangarwa bw'umubiri.Iyo sisitemu yubudahangarwa igenzuwe neza mubikorwa byose uhereye igihe havumbuwe virusi, urutonde rwa virusi nkuko byifuzwa, gukora antibodi, kurandura virusi… kugeza igihe cyo kwibuka kwa nyuma kw’umubiri no guhagarika umuriro. , ntidushobora kwandura byoroshye mugukurura intambara na virusi, kandi turashobora gukuraho virusi kandi twirinda ko twongera kubaho nubwo twanduye.

Ntiwibagirwe, nubwo virusi ya hepatite B yahanaguwe kandi ntishobora kuboneka mu mubiri (HBsAg negatif ihinduka), ibikoresho byayo bikomeza kuba byinjijwe muri selile yumwijima nucleus cyangwa chromosomes.Igihe cyose ifashe amahirwe yo kutagira ubudahangarwa, irashobora kugaruka.Virusi ni amayeri cyane, nigute dushobora gukomeza kurya Ganoderma lucidum?Reba

1.Chen Peiqiong.Kwitegereza kwa Lamivudine hamwe na Ganoderma lucidum capsules mu kuvura abantu 30 barwaye hepatite idakira B. Ubuvuzi bushya bw'Abashinwa.2007;39 (3): 78-79.
2. Chen Duan n'abandi.Ingaruka za entecavir zifatanije na Ganoderma lucidum capsules mukuvura selile Th17 mumaraso ya peripheri yabarwayi barwaye hepatite idakira B. Shizhen Guoyi Guoyao.2016;27 (6): 1369-1371.
3. Shen Huajiang.Ganoderma lucidum decoction ihujwe na adefovir dipivoxil mukuvura hepatite B idakira n'ingaruka zayo mumikorere yubudahangarwa.Ikinyamakuru Zhejiang cyubuvuzi gakondo bwabashinwa.2011;46 (5): 320-321.
4. Li Yulong.Ubushakashatsi bwubuvuzi bwa adefovir dipivoxil bufatanije na capsules ya Ganoderma lucidum mu kuvura indwara ya hepatite idakira B. Ikinyamakuru cy’ubuvuzi cya Sichuan.2013;34 (9): 1386-1388.

IHEREZO

Ibyerekeye umwanditsi / Madamu Wu Tingyao
Wu Tingyao yagiye atanga amakuru ku makuru ya Ganoderma lucidum kuva mu 1999. Ni umwanditsi wa Healing hamwe na Ganoderma (yasohotse mu nzu y’ubuvuzi y’abaturage muri Mata 2017).
 
★ Iyi ngingo yasohowe uruhushya rwihariye rwumwanditsi, kandi nyirubwite ni GANOHERB.Work Ibikorwa byavuzwe haruguru ntibishobora kubyara, gucibwa cyangwa gukoreshwa mubundi buryo utabiherewe uburenganzira na GanoHerb.★ Niba imirimo yemerewe gukoreshwa, igomba gukoreshwa murwego rwo gutanga uburenganzira no kwerekana inkomoko: GanoHerb.★ Ku kurenga ku magambo yavuzwe haruguru, GanoHerb azakomeza inshingano zijyanye n'amategeko.Text Umwandiko wumwimerere wiyi ngingo wanditswe mu gishinwa na Wu Tingyao uhindurwa mu cyongereza na Alfred Liu.Niba hari itandukaniro riri hagati yubuhinduzi (icyongereza) numwimerere (igishinwa), igishinwa cyumwimerere kizatsinda.Niba abasomyi bafite ikibazo, nyamuneka hamagara umwanditsi wambere, Madamu Wu Tingyao.

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