A cikin labarin "Tsarin asibiti guda uku naGanoderma luciduma inganta ciwon hanta na kwayar cuta, mun ga binciken asibiti wanda ya tabbatar da hakaGanoderma lucidumza a iya amfani da shi kadai ko a hade tare da na al'ada goyon baya da kuma symptomatic kwayoyi don taimaka marasa lafiya da kwayar cutar hepatitis yaki kumburi da cutar da kuma daidaita rashin daidaituwa rigakafi.Don haka, iyaGanoderma lucidumkuma magungunan da aka saba amfani da su na asibiti suma suna taka rawa?

Kafin mu shiga cikin wannan batu, dole ne mu fahimci cewa magungunan rigakafi ba za su iya kashe kwayar cutar ba amma suna iya hana kwafin kwayar cutar da ta shiga cikin "kwayoyin" da kuma rage yawan yaduwar cutar.

A wasu kalmomi, magungunan antiviral ba su da tasiri akan ƙwayoyin cuta waɗanda har yanzu suna "a waje da tantanin halitta" suna neman maƙasudin da ba za a iya kamuwa da su ba.Dole ne su dogara da haɗin gwiwar ƙwayoyin rigakafi da tsarin rigakafi ke samarwa da ƙwayoyin rigakafi ciki har da macrophages don kawar da kwayar cutar.

Wannan shine dalilin da ya sa akwai dakin magungunan antiviral daGanoderma lucidumyin aiki hannu da hannu – sabodaGanoderma lucidumyana da kyau a tsarin rigakafi, zai iya daidaita ƙarancin magungunan antiviral;kumaGanoderma lucidumTasirin hanawa akan kwafin ƙwayoyin cuta shima babban haɓaka ne ga magungunan rigakafi.

A cewar rahotanni na asibiti da aka buga, ko ana amfani da su tare da magungunan rigakafi irin su Lamivudine, Entecavir ko Adefovir fiye da shekara guda.Ganoderma lucidumbaya tsoma baki tare da inganci ko haifar da mummunan halayen.Akasin haka, yana iya taimakawa marasa lafiya na hepatitis B na yau da kullun don cimma "sauri" ko "mafi kyau" anti-inflammatory and antiviral effects, rage abin da ya faru na juriya na miyagun ƙwayoyi, da kuma inganta cututtuka na yau da kullum.Tasirin wannan ƙari ɗaya yana da girma wanda babu dalilin da zai hana amfani da su tare.

Daya daga cikin fa'idodin "Ganoderma lucidum+ magungunan rigakafi” ba shi da sauƙi don haɓaka juriya na ƙwayoyi.

A cewar wani rahoton asibiti da kwalejin likitanci ta biyu ta jami'ar Guangzhou ta kasar Sin ta bayar a shekarar 2007, a cikin majinyata da ke fama da ciwon hanta na B da suka samu 6.Ganoderma lucidumcapsules kowace rana jimlar 1.62 grams (daidai da 9 grams naGanoderma lucidum'ya'yan itace) tare da maganin rigakafi na lamivudine na tsawon shekara guda, wasu daga cikinsu kuma an yi musu magani da magungunan tallafi da alamun bayyanar cututtuka maimakon sauran magungunan rigakafi.

A sakamakon haka, ciwon hanta ya sami sauƙi da sauri, ba a gano DNA na kwayar cutar ba a cikin jinin mai haƙuri (wanda ke wakiltar cewa an rage yawan kwayar cutar zuwa baya zubewa cikin jini daga hanta), kuma damar e antigen ya ɓace / juya mara kyau. in mun gwada da girma (ba a sake haifar da kwayar cutar da karfi ba).A lokaci guda, yuwuwar maye gurbi na juriya na miyagun ƙwayoyi a cikin ƙwayoyin cuta ya ragu sosai.

Kamar yadda babu wani sakamako mara kyau na asibiti a duk lokacin jiyya, babu wani canje-canje mara kyau a cikin aikin jini na yau da kullun da gwaje-gwaje na aikin renal, lokuta 2 na gudawa a cikin rukunin rigakafin ƙwayar cuta mai tsafta da kuma yanayin 1 kawai na ciwon kai mai laushi a rukunin Ganoderma, amma duk waɗannan lokuta 3 duk sun iya spontaneously sauƙaƙa, ya nuna cewa jiyya naGanoderma lucidumhade tare da maganin rigakafi ba kawai tasiri ba amma har da lafiya.

Ganoderma lucidum ba kawai zai iya inganta ingancin magungunan ƙwayoyin cuta ba amma har ma ya ba marasa lafiya da tasirin immunomodulatory wanda magungunan antiviral ba su da shi.Wani rahoto na asibiti da aka buga a shekarar 2016 ta Cibiyar dakunan gwaje-gwaje na Clinical na birnin Huangshi, lardin Hubei, ya gano cewa, bayan shekara guda na jinyar marasa lafiya da ke fama da ciwon hanta, tare da 6 Ganoderma lucidum capsules da aka yi da Ganoderma lucidum 'ya'yan itacen ruwan jikin da ya kai gram 1.62 (daidai da gram 9) na Ganoderma lucidum fruiting body) a kowace rana da maganin rigakafi na Entecavir, ma'aunin hanta ya dawo daidai, kwayar cutar ta ragu, yiwuwar kwafin ƙwayoyin cuta ya zama mai rauni, kuma ƙwayoyin Th17 masu alaƙa da kumburi a cikin jini suna raguwa. yana haifar da kumburin hanta saboda tsarin rigakafi dole ne ya kai hari ga ƙwayoyin hanta don cire ƙwayoyin cuta da ke ɓoye a cikin sel.Lokacin da yaki tsakanin ƙwayoyin cuta da rigakafi ba zai ƙare ba, tsarin rigakafi yana raguwa a hankali tsakanin inganta kumburi (anti-virus) da kuma hana kumburi (kwayoyin kariya).Ɗaya daga cikin ƙayyadaddun alamunsa shine yawan samar da ƙwayoyin Th17 a cikin mataimaki T Kwayoyin (Th cells) waɗanda ke ba da umarnin tsarin rigakafi don yin yaki.

Kwayoyin Th17 ana amfani dasu da yawa don inganta kumburi da yaki da kamuwa da cuta.Lokacin da adadin su ya yi yawa, zai rage sauran rukunin T (TReg) sel waɗanda ke da alhakin hana kumburi.Haɗuwa da amfani da Ganoderma lucidum da Entecavir na iya rage ƙananan ƙwayoyin Th17, wanda babu shakka yana taimakawa wajen inganta kumburin hanta - don haka adadin lokuta inda ma'anar hanta ya koma al'ada zai kasance fiye da na Entecavir da aka yi amfani da shi kadai.

Kamar yadda magungunan antiviral na iya hana kwafin ƙwayoyin cuta kawai kuma ba su da ikon tsara rigakafi, raguwar Th17 a fili yana da alaƙa da Ganoderma lucidum;saboda raguwar Th17 ba zai shafi tasirin cutar ba, Ganoderma lucidum bai kamata kawai ya gyara kwayoyin Th17 ba amma kuma ya inganta rashin daidaituwa na rigakafi na marasa lafiya na hepatitis B.
Wani rahoto na asibiti da asibitin mutane na shida na birnin Shaoxing na lardin Zhejiang ya buga a shekarar 2011 ya kuma lura da marasa lafiya na ciwon hanta na B da aka yi musu maganin 100 ml na Ganoderma lucidum decoction (wanda aka yi da giram 50 na Ganoderma lucidum 'ya'yan itace da gram 10 na ja dabino da ruwa). hade da maganin rigakafi Adefovir tsawon shekaru biyu a jere.Wannan magani ba wai kawai yana da sakamako mai kyau na kawar da cutar hanta ba ko kuma danne kwayar cutar hanta amma kuma yana da tasirin daidaita tsarin rigakafi, gami da haɓaka adadin ƙwayoyin kisa na halitta, ƙwayoyin T da CD4+ T-cell subsets a cikin lymphocytes, kuma ta hanyar haɓakar ƙwayoyin cuta. CD4+ don ƙãra rabon CD4+/CD8+ T-cell subset, sa shi kusa da kyakkyawan yanayin lafiya.

Marasa lafiya na ciwon hanta na B na yau da kullun suna fuskantar raguwar ƙwayoyin T gabaɗaya, raguwar adadin CD4+ da ƙaruwar adadin CD8+ yayin da yanayin cutar ke ƙara tsayi, yana haifar da raguwar rabon CD4+/CD8+.Kwayoyin CD4+ T tare da alamun CD4+ a jikin tantanin halitta sun ƙunshi "masu taimakawa T cell" ko "kwayoyin T masu kayyade", wanda zai iya ba da umarni ga dukan sojojin na rigakafi don yin yaki (ciki har da ba da umarnin B Kwayoyin don samar da kwayoyin rigakafi) da kuma magance kumburi a cikin lokaci. ;da CD8+ T da CD8+ alamomin kwayoyin halitta a saman tantanin halitta, galibinsu “masu kashe kwayoyin halitta” ne da kan iya kashe kwayoyin cutar da suka kamu da cutar (da ciwon daji).Dukkan rukunonin T sun bambanta da ƙwayoyin T na farko, don haka suna shafar juna a lamba.Lokacin da kwayar cutar ta ci gaba da kamuwa da kwayoyin halitta, takan haifar da adadi mai yawa na ƙwayoyin T don bambanta zuwa ƙwayoyin kisa T (CD8+), wanda a zahiri yana rinjayar adadin CD4+ da umarninsa da haɗin kai.Irin wannan ci gaban zai shafi garkuwar garkuwar jiki ta anti-viral da anti-inflammatory, kuma yana da illa ga maganin ciwon hanta.

Sabili da haka, haɗuwa da amfani da Ganoderma lucidum da maganin antiviral adefovir dipivoxil zai iya ƙara yawan adadin ƙwayoyin T da CD4+ a cikinsu, ta haka yana ƙara CD4+/CD8+ rabo, kuma a lokaci guda dan kadan ƙara yawan ƙwayoyin kisa na halitta waɗanda ke da amfani. anti-virus da anti-tumor.Wadannan alamu ne na inganta aikin rigakafi na marasa lafiya da ke fama da ciwon hanta na kullum, kuma tasirin ya fi na marasa lafiya da aka yi wa maganin rigakafi kawai.
 
Bugu da ƙari, rahoton na asibiti ya kuma rubuta cewa babu rash, gastrointestinal reaction, creatine kinase (creatinine) karuwa da rashin aikin koda ya faru a cikin dukkanin batutuwa yayin aikin jiyya, wanda ya kara tabbatar da lafiyar Ganoderma lucidum a cikin maganin antiviral adjuvant.Abubuwan anti-viral da anti-mai kumburi suna taimakawa hana hanta daga taurin hankali a hankali da ciwon daji yayin maimaita kumburi da gyare-gyare, yana nuna mahimmancin su ga marasa lafiya da ciwon hanta na kullum.Idan za a iya rage alamun fibrosis na hanta a lokacin maganin ciwon hanta na B, wannan kuma zai iya zama wata hujja cewa maganin yana da tasiri.

Rahoton asibiti da Asibitin mutane na hudu na birnin Panzhihua na lardin Sichuan ya fitar a shekarar 2013, ta hanyar jinyar makwanni 48 (kimanin shekaru 1) na masu fama da ciwon hanta na ciwon hanta da ke dauke da capsules guda 9 na Ganoderma lucidum wanda ya kai giram 2.43 a kowace rana (daidai da g 13.5). na Ganoderma lucidum fruiting body) hade da maganin rigakafi Adefovir dipivoxil da hanta-kare, alamun bayyanar cututtuka da magungunan tallafi, sun gano cewa alamun cutar hanta na majiyyaci an inganta su sosai, kuma alamomi guda huɗu a cikin jinin marasa lafiya da ke da alaƙa da fibrosis hanta su ma sun ragu daga sama. na al'ada zuwa al'ada ko kusa da al'ada.Waɗannan sharuɗɗan sun nuna cewa ƙarin tasirin Ganoderma lucidum da magungunan rigakafi kuma ana iya bayyana su wajen hana cutar hanta.

Ya kamata a ambata cewa a cikin marasa lafiya 60 da suka karɓi duka Ganoderma lucidum da adefovir dipivoxil magani, marasa lafiya 3 (5%) ba su da kwayar cutar hanta ta B (HBsAg korau mai canzawa) kuma sun samar da ƙwayoyin rigakafi zuwa kwayar cutar (Anti-HBs tabbatacce). an kammala maganin.Irin wannan tasirin magani ba shi da sauƙin samun idan aka kwatanta da burin cewa kawai 1% na marasa lafiya na hepatitis B masu karɓar maganin rigakafi na iya gane mummunan juzu'i a kowace shekara.Ganoderma lucidum na iya inganta ingancin magungunan antiviral, wanda kuma an sake tabbatar da shi.Ganoderma lucidum 'ya'yan itace mai cire ruwa na jiki zai iya tsara duk wani nau'i na rigakafi.Kyakkyawan rigakafi zai iya hana kamuwa da cuta, rashin lafiya na yau da kullum da sake dawowa.

Rahotannin asibiti guda hudu da ke sama ba wai kawai sun nuna fa'idar Ganoderma lucidum ba wajen taimaka wa magungunan kashe kwayoyin cuta wajen maganin ciwon hanta na kullum amma kuma sun nuna yiwuwar amfani da Ganoderma lucidum da sauran magungunan kashe kwayoyin cuta a hade.

Ganoderma lucidum capsules da Ganoderma lucidum decoction da aka yi amfani da su a cikin bincike duka biyun ruwan 'ya'yan itace ne na Ganoderma lucidum 'ya'yan itace.

Abubuwan da ke aiki da ake samu ta hanyar fitar da ganoderma lucidum mai 'ya'yan itace da ruwa sune galibi polysaccharides ciki har da polysaccharide peptides da glycoproteins, da kuma ɗan triterpenoids.Wadannan sinadaran sune tushen aiki na Ganoderma lucidum don daidaita aikin rigakafi.Haɗin triterpenoids wanda zai iya hana kumburi mara kyau da hana kwafin ƙwayar cuta ba shakka zai yi cikakken bayanin tasirin Ganoderma lucidum a cikin taimakon magungunan rigakafin cutar.

A haƙiƙa, mabuɗin mafi mahimmanci don magance cututtukan ƙwayoyin cuta da ma hana kamuwa da cuta iri-iri shine tsarin rigakafi.Lokacin da tsarin rigakafi ya sami tsari mai kyau a cikin dukkanin tsari daga gano kwayar cutar, lissafin kwayar cutar kamar yadda ake so, samar da kwayoyin cuta, kawar da kwayar cutar… zuwa samuwar ƙwaƙwalwar ajiya ta ƙarshe da kuma ƙarewar kumburi. , ƙila ba za mu iya kamuwa da cutar cikin sauƙi a yaƙi da ƙwayoyin cuta ba, kuma za mu iya kawar da kwayar cutar kuma mu guje wa sake dawowa ko da mun kamu da cutar.

Kar a manta, ko da cutar hanta B ta barranta kuma ba za a iya samunta a cikin jiki ba (HBsAg negative converting), kwayoyin halittarsa ​​har yanzu yana iya kasancewa a cikin kwayar hanta ko chromosomes.Muddin ya sami damar raunin rigakafi, zai iya yin komowa.Kwayar cutar tana da wayo, ta yaya ba za mu ci gaba da cin Ganoderma lucidum ba?Magana

1. Chen Peiqiong.Binciken asibiti na Lamivudine tare da Ganoderma lucidum capsules a cikin kula da marasa lafiya 30 masu fama da ciwon hanta na kullum. Sabon likitancin kasar Sin.2007;39 (3): 78-79.
2. Chen Duan et al.Sakamakon entecavir tare da Ganoderma lucidum capsules a cikin maganin kwayoyin Th17 a cikin jini na jini na marasa lafiya tare da ciwon hanta na kullum B. Shizhen Guoyi Guoyao.2016;27 (6): 1369-1371.
3. Shen Huajiang.Ganoderma lucidum decoction hade da adefovir dipivoxil a cikin maganin ciwon hanta na kullum da kuma tasirinsa akan aikin rigakafi.Jaridar Zhejiang ta Magungunan Gargajiya ta kasar Sin.2011;46 (5): 320-321.
4. Li Yulong.Nazarin asibiti na adefovir dipivoxil hade tare da Ganoderma lucidum capsules a cikin maganin ciwon hanta na kullum B. Sichuan Medical Journal.2013;34 (9): 1386-1388.

KARSHE

Game da marubucin / Ms. Wu Tingyao
Wu Tingyao tana ba da rahoto kan bayanan Ganoderma lucidum na farko tun daga 1999. Ita ce marubucin Healing with Ganoderma (wanda aka buga a cikin Gidan Buga Likitan Jama'a a cikin Afrilu 2017).
 
★ An buga wannan labarin ne a ƙarƙashin izini na musamman na marubucin, kuma mallakin GANOHERB ne.★ Ayyukan da ke sama ba za a iya sake su ba, cire su ko amfani da su ta wasu hanyoyi ba tare da izinin GanoHerb ba.★ Idan an ba da izinin yin amfani da ayyukan, to a yi amfani da su cikin iyakar izini kuma a nuna tushen: GanoHerb.★ Duk wani keta bayanin da ke sama, GanoHerb za ta bi alhakin shari'a masu alaƙa.★ Asalin rubutun wannan labarin Wu Tingyao ne ya rubuta shi da Sinanci kuma Alfred Liu ya fassara shi zuwa Turanci.Idan akwai wani sabani tsakanin fassarar (Turanci) da na asali (China), asalin Sinanci zai yi nasara.Idan masu karatu suna da wasu tambayoyi, tuntuɓi marubuciyar asali, Ms. Wu Tingyao.

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