Ku ya 1 Werurwe 2018 / Ishuri Rikuru ry'Uburusiya / Phytomedicine

Inyandiko / Wu Tingyao

Muri Werurwe 2018, urupapuro rwasohowe muri Phytomedicine n'Ikigo cya Cytology na Genetika mu Ishuri Rikuru ry'Ubumenyi bw'Uburusiya ryemeje ko nyuma y'ibyumweru birindwi bigaburiraGanoderma lucidum.Ganoderma lucidumkuvoma amazi biragereranywa nibya Losartan (reba Ishusho 1).

Ubushakashatsi bw’inyamaswa bwagaragaje kandi ko ku mbeba zifite umuvuduko ukabije wavuweGanoderma lucidumamazi akuramo, ubwinshi bwamaraso yimitsi ya karotide yiyongereye cyane, bikubye hafi kabiri abadafite imiti (reba Ishusho 2).Muri icyo gihe, diameter ya karotide na umuvuduko wamaraso nabyo byiyongereye cyane.Ibi bivuze ko amaraso atembera mubwonko bwimbeba ntagabanuka nigabanuka ryumuvuduko wamaraso ahubwo igakora cyane kandi ikagwira bitewe naGanoderma lucidum.Ibinyuranye na byo, nubwo diameter ya karotide yimbeba yimbeba zo mumatsinda ya hypotensive yiyongereye, umuvuduko wamaraso ntiwarenze uw'itsinda rishinzwe kugenzura, kandi ubwinshi bwamaraso ntabwo bwari butandukanye cyane nubw'itsinda rishinzwe kugenzura.

Muri Werurwe 2018, urupapuro rwasohowe muri Phytomedicine n'Ikigo cya Cytology na Genetika mu Ishuri Rikuru ry'Ubumenyi bw'Uburusiya ryemeje ko nyuma y'ibyumweru birindwi bigaburiraGanoderma lucidum.Ganoderma lucidumkuvoma amazi biragereranywa nibya Losartan (reba Ishusho 1).

Ubushakashatsi bw’inyamaswa bwagaragaje kandi ko ku mbeba zifite umuvuduko ukabije wavuweGanoderma lucidumamazi akuramo, ubwinshi bwamaraso yimitsi ya karotide yiyongereye cyane, bikubye hafi kabiri abadafite imiti (reba Ishusho 2).Muri icyo gihe, diameter ya karotide na umuvuduko wamaraso nabyo byiyongereye cyane.Ibi bivuze ko amaraso atembera mubwonko bwimbeba ntagabanuka nigabanuka ryumuvuduko wamaraso ahubwo igakora cyane kandi ikagwira bitewe naGanoderma lucidum.Ibinyuranye na byo, nubwo diameter ya karotide yimbeba yimbeba zo mumatsinda ya hypotensive yiyongereye, umuvuduko wamaraso ntiwarenze uw'itsinda rishinzwe kugenzura, kandi ubwinshi bwamaraso ntabwo bwari butandukanye cyane nubw'itsinda rishinzwe kugenzura.

Igishushanyo 2 Ingaruka zaGanoderma lucidumamazi akuramo umuvuduko wamaraso

[Icyitonderwa] Inzira yubushakashatsi nimwe nkuko byavuzwe haruguru.Nyuma yibyumweru birindwi bivurwa, umuvuduko wamaraso wa karotide yitsinda rya Reishi wari hejuru cyane ugereranije nandi matsinda abiri.(Inkomoko / Phytomedicine.2018 Werurwe 1; 41: 1-6.)

Isesengura ryakozwe kuri 12 nyamukuru ya neurotransmitter yasohowe nubwonko bwubwonko bwa buri tsinda ryimbeba, byagaragaye ko ikuramo amazi yaGanoderma lucidumumubiri wera imbuto ushobora guhindura igipimo cya neurotransmitter zimwe na zimwe, bigatuma inzitizi zangiza za neurotransmitter (nka glycine, zitwa Gly) hamwe na neurotransmitter zishimishije (nka glutamine, bita Glx) hafi yigihugu kiringaniye, kandi leta nkiyi irafasha umuvuduko w'amaraso usanzwe.

Igisubizo cyerekana ko ugereranije na Losartan, irwanya antagonist ya AT1 yakira angiotensin Ⅱ kwagura imiyoboro yamaraso no kugenzura umuvuduko wamaraso,Ganoderma lucidumkuvoma amazi biragoye cyane mugutunganya umuvuduko wamaraso kandi bifitanye isano no kugenga sisitemu yimitsi.

Icyitegererezo cy’inyamanswa zikoreshwa muri ubwo bushakashatsi ni "umurage watewe na hypertension arterial", ni ukuvuga itegeko nshinga ryarazwe na se cyangwa nyina bitera umuvuduko ukabije w'amaraso, kandi guhangayika mu mutwe nicyo kintu nyamukuru gitera.Ibi mubyukuri bihuye nimiterere yabarwayi benshi bafite hypertension ya hereditaire ya etiologiya itazwi: ihungabana ryimikorere ya nervous sisitemu iterwa no guhangayika (imikorere yimikorere idahwitse hagati yimitsi yimpuhwe yiganjemo imyakura ya neurotransmitter hamwe na parasimpatique yiganjemo ibuza neurotransmitters) itera umuvuduko wamaraso burigihe hejuru kandi bigoye gusubira murwego rusanzwe.

Niba udasobanukiwe isano iri hagati yumutima wigenga numuvuduko wamaraso, urashobora kwiyumvisha ko umuvuduko wamaraso utera bitewe numunezero wamarangamutima (wiganjemo sisitemu yimpuhwe zimpuhwe) mugihe ureba umukino wumupira wamaguru, ariko umuvuduko wamaraso ugabanuka mubisanzwe nyuma igihe cyo kuruhuka (cyiganjemo sisitemu ya parasimpatique).Ubu ni uburyo busanzwe bwo kugenzura.Umuvuduko wamaraso ntushobora gusubira mubisanzwe kuruhuka, gusinzira, no kuruhuka mumarangamutima, hazabaho ikibazo cyumuvuduko ukabije wamaraso.Ku bijyanye n’uko umuvuduko wamaraso ugera ku ndwara zasobanuwe n’ubuvuzi zisaba imiti, biterwa n’uko umuvuduko wamaraso wa systolique cyangwa diastolique urenze agaciro kateganijwe - mugihe kimwe murimwe kidasanzwe, gifatwa nkumuvuduko ukabije wamaraso.

Hariho ibice byinshi byubwonko bishobora kugira ingaruka kumaraso no kumutima.Mubisanzwe, bigengwa nubwonko bwubwonko (“ubwonko bwo hejuru bwubwonko bwo kugenzura ubwenge”).Mbere, irindi tsinda ry’abashakashatsi bo mu Ishuri Rikuru ry’Ubumenyi ry’Uburusiya ryemeje ko mu mbeba zifite “umurage uterwa n’umuvuduko ukabije wa arterial hypertension”, ubwonko bw’ubwonko burekura ibintu byinshi bitera imbaraga za neurotransmitter, bigatuma umuvuduko w'amaraso uba mwinshi.Noneho, mubigeragezo hamweGanoderma lucidum, byagaragaye ko ubuyobozi bwo mu kanwa bwaGanoderma lucidumAmazi akuramo ibyumweru birindwi bikurikiranye arashobora kugenga imiyoboro ya neurotransmitter isohorwa nubwonko bwubwonko kandi igatera imbere cyane hypertension.

Naho izo mbeba zifite umuvuduko ukabije wariyeGanoderma lucidumimbuto zivamo umubiri, umuvuduko wamaraso wubwonko bwiyongereye kandi umuvuduko wamaraso wiyongera.Kubwibyo, umushakashatsi yerekanye arangije raporo koGanoderma lucidumibiyikuramo birashobora kugira ingaruka za nootropic.

Niba kuryaGanodermalucidumIrashobora rwose gutanga ingaruka za nootropique, igomba kugaragazwa nubundi bushakashatsi.Ariko kubarwayi bafite umuvuduko ukabije wamaraso etiologiya itazwi (idatewe na diyabete n'indwara zimpyiko),Ganoderma lucidumibicuruzwa birimoGanoderma lucidumimbuto zivamo umubiri zigomba kuba zikwiye kugerageza.NiburaGanoderma lucidumntabwo itanga ingaruka mbi nko kuzunguruka, kuzunguruka mu mazuru, inkorora, no kugira isesemi bikunze kugaragara ku miti rusange igabanya ubukana.

Birakwiye kuvuga ko ubushakashatsi bwashize bwemeje koGanoderma lucidumtriterpène irashobora guhagarika ibikorwa bya angiotensin ihindura enzyme (ACE) kugirango Angiotensin I narekuwe nimpyiko idashobora gutangizwa na ACE muri Angiotensin II ishobora guteza vasoconstriction.Noneho, ibivamo amazi yaGanoderma lucidumumubiri wera, ugizwe ahanini na polysaccharide, byagaragaye ko uzamura umuvuduko ukabije wamaraso muguhindura sisitemu yimitsi.Ubwuzuzanye bwa triterpenoide na polysaccharide byongeye kubyemezaGanoderma lucidumhamwe nibikoresho byuzuye (birimo triterpenoide na polysaccharide) nuguhitamo kwiza.

[Inkomoko] Shevelev OB, n'abandi.Ingaruka za hypotensive na neurometabolic ya intragastric Reishi (Ganoderma lucidum) ubuyobozi muri hypertension ISIAH imbeba.Phytomedicine.2018 Werurwe 1;41: 1-6.

IHEREZO

Ibyerekeye umwanditsi / Madamu Wu Tingyao

Wu Tingyao yagiye atanga amakuru ku makuru ya Ganoderma kuva mu 1999. Ni umwanditsi waGukiza hamwe na Ganoderma(byasohotse mu gitabo cy’ubuvuzi cy’abaturage muri Mata 2017).

★ Iyi ngingo yasohowe uruhushya rwihariye rwumwanditsi.Works Ibikorwa byavuzwe haruguru ntibishobora gusubirwamo, gucibwa cyangwa gukoreshwa mubundi buryo utabiherewe uburenganzira n'umwanditsi.★ Kurenga ku magambo yavuzwe haruguru, umwanditsi azakurikirana inshingano zemewe n'amategeko.Text Umwandiko wumwimerere wiyi ngingo wanditswe mu gishinwa na Wu Tingyao uhindurwa mu cyongereza na Alfred Liu.Niba hari itandukaniro riri hagati yubuhinduzi (icyongereza) numwimerere (igishinwa), igishinwa cyumwimerere kizatsinda.Niba abasomyi bafite ikibazo, nyamuneka hamagara umwanditsi wambere, Madamu Wu Tingyao.