Maachị 1, 2018 / Russian Academy of Sciences / Phytomedicine

Ederede / Wu Tingyao

Na March 2018, akwụkwọ bipụtara na Phytomedicine nke Institute of Cytology and Genetics of the Russian Academy of Sciences kwadoro na mgbe izu asaa nke nri gasịrị.Ganoderma lucidum(Reishi) mmiri ahụ na-amịpụta mkpụrụ nye ụmụ oke na-ata ahụhụ site na mgbakasị ahụ ketara eketa na-akpata ọbara mgbali elu, mmetụta hypotensive nkeGanoderma lucidumMwepụta mmiri dị ka nke Losartan (lee foto 1).

Nnwale anụmanụ ahụ chọpụtakwara na maka oke ọbara mgbali elu na-emeso yaGanoderma lucidummmịpụta mmiri, ụda ọbara nke akwara carotid ha mụbara nke ukwuu, ihe dị ka okpukpu abụọ karịa nke ndị na-enweghị ọgwụgwọ ọ bụla (lee foto 2).N'otu oge ahụ, dayameta akwara carotid na ọnụ ọgụgụ ọbara na-abawanye nke ukwuu.Nke a pụtara na ọ naghị ebelata ọbara na-eruba na ụbụrụ oke site na mbelata nke ọbara mgbali kama kama ọ na-arụsi ọrụ ike ma na-aba ụba n'okpuru mmetụtaGanoderma lucidum.N'ụzọ dị iche, ọ bụ ezie na dayameta carotid artery nke oke dị n'ime ìgwè ọgwụ hypotensive mụbara, ọnụọgụ ọbara agafeghị nke ndị na-achịkwa ya, na ọbara na-erugharị adịghịkwa iche na nke ndị na-achịkwa.

Na March 2018, akwụkwọ bipụtara na Phytomedicine nke Institute of Cytology and Genetics of the Russian Academy of Sciences kwadoro na mgbe izu asaa nke nri gasịrị.Ganoderma lucidum(Reishi) mmiri ahụ na-amịpụta mkpụrụ nye ụmụ oke na-ata ahụhụ site na mgbakasị ahụ ketara eketa na-akpata ọbara mgbali elu, mmetụta hypotensive nkeGanoderma lucidumMwepụta mmiri dị ka nke Losartan (lee foto 1).

Nnwale anụmanụ ahụ chọpụtakwara na maka oke ọbara mgbali elu na-emeso yaGanoderma lucidummmịpụta mmiri, ụda ọbara nke akwara carotid ha mụbara nke ukwuu, ihe dị ka okpukpu abụọ karịa nke ndị na-enweghị ọgwụgwọ ọ bụla (lee foto 2).N'otu oge ahụ, dayameta akwara carotid na ọnụ ọgụgụ ọbara na-abawanye nke ukwuu.Nke a pụtara na ọ naghị ebelata ọbara na-eruba na ụbụrụ oke site na mbelata nke ọbara mgbali kama kama ọ na-arụsi ọrụ ike ma na-aba ụba n'okpuru mmetụtaGanoderma lucidum.N'ụzọ dị iche, ọ bụ ezie na dayameta carotid artery nke oke dị n'ime ìgwè ọgwụ hypotensive mụbara, ọnụọgụ ọbara agafeghị nke ndị na-achịkwa ya, na ọbara na-erugharị adịghịkwa iche na nke ndị na-achịkwa.

Ọgụgụ 2 Mmetụta nkeGanoderma lucidummmịpụta mmiri na akwara ọbara ọgbụgba

[Cheta] Usoro nnwale bụ otu ihe ahụ dị n'elu.Mgbe izu asaa nke ọgwụgwọ gasịrị, ọnụ ọgụgụ ọbara carotid nke Reishi dị elu karịa nke otu abụọ ndị ọzọ.(Isi mmalite/Phytomedicine.2018 Mar 1; 41:1-6.)

Ntụle ọzọ nke 12 isi neurotransmitters zoro ezo site na cerebral cortex nke ọ bụla ìgwè oke, a chọpụtara na mmiri wepụ nke.Ganoderma lucidumahụ na-amị mkpụrụ nwere ike ịgbanwe nha nke ụfọdụ neurotransmitters, na-eme ka ndị na-egbochi neurotransmitters (dị ka glycine, nke a na-akpọ Gly) na neurotransmitters na-akpali akpali (dị ka glutamine, nke a na-akpọ Glx) nso na steeti ziri ezi, na steeti dị otú ahụ na-enyere aka. ọbara mgbali nkịtị.

Nsonaazụ a na-egosi na e jiri ya tụnyere Losartan, nke na-emegide ndị na-emegide AT1 ndị na-anabata angiotensin Ⅱ iji gbasaa arịa ọbara na ịchịkwa ọbara mgbali,Ganoderma lucidumMwepụ mmiri na-agbagwoju anya karị n'ịchịkwa ọbara mgbali elu ma na-ejikọta ya na nhazi nke usoro nhụjuanya cranial.

Ụdị anụmanụ ndị e ji mee nnwale ahụ bụ “oke ọbara mgbali elu na-akpata nrụgide”, ya bụ, iwu e ketara n’aka nna ma ọ bụ nne nke na-ebute ọbara mgbali elu n’ụzọ dị mfe, na nchekasị uche bụ isi ihe na-akpata.Nke a bụ n'ezie na ọnọdụ nke ọtụtụ ndị ọrịa na-eketa ọbara mgbali elu nke amaghị etiology: autonomic ụjọ usoro ọrịa kpatara nrụgide (na-achịkwa ọrụ ahaghị nhata n'etiti akwara ọmịiko na-achịkwa excitatory neurotransmitters na parasympathetic akwara na-achịkwa inhibitory neurotransmitters) na-eme ka ọbara mgbali elu. mgbe niile dị elu ma sie ike ịlaghachi na ọkwa nkịtị.

Ọ bụrụ na ị ghọtaghị mmekọrịta dị n'etiti akwara autonomic na ọbara mgbali elu, ị nwere ike iche n'echiche na ọbara mgbali elu na-agbapụta n'ihi obi ụtọ nke mmetụta uche (nke usoro nhụjuanya ọmịiko na-achịkwa) mgbe ị na-ekiri egwuregwu football, ma ọbara mgbali na-adaghachi azụ na nkịtị mgbe e mesịrị. oge ezumike (nke usoro nhụjuanya parasympathetic na-achịkwa).Nke a bụ usoro iwu nkịtị.Ozugbo ọbara mgbali elu enweghị ike ịlaghachi na nkịtị site na izu ike, ụra, na ntụrụndụ mmetụta uche, a ga-enwe nsogbu nke ọbara mgbali elu.N'ihe gbasara ma ọ̀tụ̀tụ̀ ọbara mgbali elu ruru ọnọdụ ọrịa ahụ akọwapụtara nke chọrọ ọgwụ, ọ dabere na ọbara mgbali elu systolic ma ọ bụ diastolic gafere uru e nyere ya - ọ bụrụhaala na otu n'ime ha adịghị mma, a na-ewere ya dị ka ọbara mgbali elu.

Enwere ọtụtụ akụkụ nke ụbụrụ nwere ike imetụta ọbara mgbali na ọnọdụ.Dị ka ọ na-adịkarị, a na-achịkwa ha site na cerebral cortex (“Ebe njikwa ikike ọgụgụ isi nke ụbụrụ”).Na mbụ, otu ndị ọzọ na-eme nchọpụta si na Russian Academy of Sciences ekwenyela na n'ime oke ndị nwere "oke ọbara mgbali elu na-akpata nrụgide na-akpata", ụbụrụ ụbụrụ na-ezobe ihe ndị na-akpali akpali nke neurotransmitters, na-eme ka ọbara mgbali elu dị elu.Ugbu a, na nnwale naGanoderma lucidum, a hụrụ na nchịkwa ọnụ nkeGanoderma lucidummmịpụta mmiri maka izu asaa n'usoro nwere ike ịhazi neurotransmitters zoro ezo site na ụbụrụ ụbụrụ ma melite ọbara mgbali elu.

Maka oke ndị nwere ọbara mgbali elu ririGanoderma lucidummkpụrụ osisi na-amịpụta mkpụrụ, ọbara ụbụrụ ha na-abawanye na mmụba ọbara ha na-abawanye.Ya mere, onye nyocha ahụ kwuru na njedebe nke akụkọ ahụGanoderma lucidumwepụ nwere ike nwere ike nootropic mmetụta.

Ma na-eri nriGanodermalucidumnwere ike mepụta mmetụta nootropic n'ezie, a ga-egosipụta ya site na nnwale ọzọ.Mana maka ndị ọrịa nwere ọbara mgbali elu nke amaghị etiology (ọ bụghị ọrịa shuga na ọrịa akụrụ kpatara),Ganoderma lucidumngwaahịa nwereGanoderma lucidumfruiting ahu extracts kwesịrị kwesịrị a na-agbalị.OpekempeGanoderma lucidumadịghị emepụta mmetụta ndị dị ka isi ọwụwa, imi imi, ụkwara, na ọgbụgbọ na-emekarị ọgwụ mgbochi hypertensive n'ozuzu.

Ọ dị mma ịkọwa na ọmụmụ ihe gara aga kwadoro nke ahụGanoderma lucidumtriterpenes nwere ike igbochi ọrụ nke angiotensin converting enzyme (ACE) nke mere na angiotensin m zoro ezo site na akụrụ enweghị ike ime ka ACE banye Angiotensin II nke nwere ike ịkwalite vasoconstriction.Ugbu a, mmiri wepụ nkeGanoderma lucidumahụ na-amị mkpụrụ, nke kachasị nke polysaccharides, ka egosipụtara na ọ na-eme ka ọbara mgbali elu dịkwuo elu site n'ịhazi usoro nhụjuanya cranial.Mmeju nke triterpenoids na polysaccharides na-akwadokwa nke ahụ ọzọGanoderma lucidumna ihe zuru oke (nke nwere ma triterpenoids na polysaccharides) bụ nhọrọ kacha mma.

[Isi iyi] Shevelev OB, et al.Mmetụta hypotensive na neurometabolic nke intragastric Reishi (Ganoderma lucidum) nchịkwa na ọbara mgbali elu ISIAH oke oke.Phytomedicine.2018 Maachị 1;41:1-6 .

N'ikpeazụ

Banyere onye odee/ Oriakụ Wu Tingyao

Wu Tingyao na-akọ akụkọ gbasara Ganoderma nke mbụ kemgbe 1999. Ọ bụ ya bụ onye dere akwụkwọ akụkọ.Ọgwụgwọ na Ganoderma(nke e bipụtara na The People's Medical Publishing House na Eprel 2017).

★ A na-ebipụta akụkọ a n'okpuru ikike nke onye edemede.★ Enweghị ike imepụtagharị ọrụ ndị a dị n'elu, wepụ ma ọ bụ jiri ya mee ihe n'ụzọ ndị ọzọ na-enweghị ikike nke onye edemede.★ Maka mmebi nke nkwupụta a dị n'elu, onye edemede ga-agbaso ọrụ iwu dị mkpa.★ Wu Tingyao dere ederede izizi nke akụkọ a n'asụsụ Chinese wee sụgharịa ya n'asụsụ Bekee site n'aka Alfred Liu.Ọ bụrụ na enwere nghọtahie n'etiti ntụgharị asụsụ (Bekee) na nke izizi (Chinese), Chinese izizi ga-emeri.Ọ bụrụ na ndị na-agụ akwụkwọ nwere ajụjụ ọ bụla, biko kpọtụrụ onye edemede mbụ bụ Oriakụ Wu Tingyao.