Ianuali 2017/Amala Cancer Research Center/Mutation Research
Text/Wu Tingyao

ʻAʻole noʻonoʻo ka hapa nui o Ganoderma lucidum a hiki i ka wā e maʻi ai lākou.Poina wale lākou hiki ke hoʻohana ʻia ʻo Ganoderma lucidum no ka mālama ʻana i ka maʻi.Wahi a kahi hōʻike i paʻi ʻia e ka Amala Cancer Research Center o India i ka "Mutation Research" i Ianuali 2017, ʻo Ganoderma lucidum triterpenes, hiki ke pale pono i ke ola ʻana o nā maʻi maʻi maʻi, hiki ke hōʻemi i ka hanana a me ka paʻakikī o nā maʻi koko, inā hoʻohana ʻia ma waho a i ʻole. i loko.
ʻO Ganoderma lucidum triterpenes ke ola maikaʻi ʻole nā ​​​​pūnaewele kanesa.
Ua hoʻohana ka haʻawina i ka huina triterpenoid extract o ke kino hua o Ganoderma lucidum.Ua hui pū nā mea noiʻi me ka MCF-7 mau pūnaeau maʻi maʻi umauma kanaka (e pili ana i ka estrogen) a ʻike ʻia ʻoi aku ka kiʻekiʻe o ka neʻe ʻana o ka extract, ʻoi aku ka lōʻihi o ka manawa e launa pū ai me nā maʻi maʻi maʻi, ʻoi aku ka hiki ke hōʻemi i ke ola o ka maʻi kanesa. nā pūnaewele, a i kekahi mau hihia, hiki iā ia ke hoʻopau loa i nā pūnana maʻi kanesa (e like me ka hōʻike ʻana ma lalo).

(Ke kiʻi hou ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)

ʻO ka loiloi hou aʻe o ka hana anti-cancer o Ganoderma lucidum total triterpenes i hōʻike ʻia ma hope o ka hoʻoponopono ʻia ʻana o nā cell cancer e Ganoderma lucidum triterpenes, nui nā genes a me nā molela protein i loko o nā cell e hoʻololi nui.Ma ka kikoʻī, e hoʻopau ʻia ka cyclin hana mua D1 a me Bcl-2 a me Bcl-xL aʻo ka Bax a me Caspase-9 mālie mua e lilo i mea hoʻomaha.

ʻO Cyclin D1, Bcl-2 a me Bcl-xL e hoʻoikaika i ka hoʻonui mau ʻana o nā maʻi maʻi maʻi ʻoiai ʻo Bax a me caspase-9 e hoʻomaka i ka apoptosis o nā maʻi maʻi maʻi i hiki ai i nā maʻi maʻi ke ʻelemakule a make e like me nā cell maʻamau.

ʻO ka hoʻokolohua hoʻohana waho: Ganoderma lucidum triterpenes pale i ka ʻili ʻili.
ʻO ka hoʻohana ʻana i ka Ganoderma lucidum total triterpenes i nā holoholona hiki ke hana i kahi hopena pale pale i nā ʻōpū.ʻO ka mua, ʻo ia ka hoʻokolohua hoʻokomo ʻana o ka “cutaneous papilloma” (Ka palapala a ka Lunahooponopono: He maʻi papillary maikaʻi kēia e puka mai ana mai ka ʻili o ka ʻili.

Ua hoʻohana ʻia ka carcinogen DMBA (dimethyl benz[a]anthracene, he polycyclic aromatic hydrocarbon compound i hiki ke hoʻololi i nā ʻano genetic) ma ke kua o ka ʻiole hoʻokolohua (ua kahi ʻia kona lauoho) e hoʻoulu ai i nā ʻili ʻili.
Ma hope o 1 pule, ua noi nā mea noiʻi i ka aila croton, kahi mea e hoʻoikaika ai i ka ulu ʻana o ka maʻi maʻi, i ka ʻāpana like ʻelua i ka pule, a hoʻohana pū i ka 5, 10, a i ʻole 20 mg o Ganoderma lucidum triterpenes 40 mau minuke ma mua o kēlā me kēia noi ʻana o ka aila croton no 8 mau ʻano. pule (ka pule 2 a 9 o ka hoʻokolohua).

Ma hope o kēlā, ua ho'ōki ka poʻe noiʻi i ka hoʻohana ʻana i nā mea ʻino a me Ganoderma lucidum akā hoʻomau i ka hāpai ʻana i nā ʻiole a nānā i ko lākou kūlana.I ka pau ʻana o ka pule 18 o ka hoʻokolohua, ʻokoʻa loa nā ʻiole i loko o ka pūʻulu hoʻomalu i mālama ʻole ʻia, me ka nānā ʻole i ka ulu ʻana o nā maʻi koko, ka nui o nā maʻi koko i ulu, a me ka manawa e ulu ai ka maʻi koko mua, ʻokoʻa loa ia mai nā ʻiole i loaʻa. hoʻohana ʻia me 5, 10, a me 20 mg o Ganoderma lucidum triterpenes (e like me ka mea i hōʻike ʻia ma ke kiʻi ma lalo).(E hoʻomaopopo: 12 mau ʻiole no kēlā me kēia hui.)

ʻO ka loaʻa ʻana o ka papilloma ʻili ma hope o 18 mau pule o ka ʻike ʻana i nā carcinogens
(Ke kiʻi ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)

ʻO ka awelika helu o nā maʻi koko ma ka ʻili o kēlā me kēia ʻiole ma hope o 18 mau pule o ka ʻike ʻana i nā carcinogens
(Ke kiʻi ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)

ʻO ka manawa e ulu ai ka maʻi maʻi ma hope o ka loaʻa ʻana o nā carcinogens
(Ke kiʻi ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)
Hoʻokolohua hānai: Ganoderma lucidum triterpenes pale i ka maʻi maʻi umauma.
ʻO ka lua, ʻo ia ka hoʻokolohua "maʻi maʻi umauma": hānai ʻia nā ʻiole carcinogen DMBA i hoʻokahi manawa i ka pule no 3 mau pule, a mai ka lā aʻe ma hope o ka hānai mua ʻana i ka carcinogen (24 mau hola ma hope), 10, 50 a i ʻole 100 mg / kg o Ganoderma lucidum triterpenes ua hānai ʻia i kēlā me kēia lā no 5 mau pule.
Ua aneane like nā hopena me nā hoʻokolohua papilloma ʻili ma mua.ʻO ka hui hoʻomalu me ka loaʻa ʻole o ka lāʻau lapaʻau he 100% ka manawa o ka hoʻomohala ʻana i ka maʻi maʻi umauma.Hiki i ka Ganoderma lucidum triterpenes ke hoʻemi nui i ka nui o nā maʻi maʻi;ʻokoʻa loa nā ʻiole i ʻai iā Ganoderma lucidum mai nā ʻiole ʻaʻole i ʻai iā Ganoderma lucidum i ka nui o nā maʻi koko i ulu a me ka manawa e ulu ai ka maʻi koko mua (e like me ka mea i hōʻike ʻia ma ke kiʻi ma lalo).
ʻO ke kaumaha o nā ʻiole i pale ʻia me ka 10, 50 a i ʻole 100 mg/kg huina pau o Ganoderma lucidum triterpenes he ʻelua hapakolu wale nō, hoʻokahi hapa a me ka hapakolu o nā paona ʻiole o nā ʻiole i loko o ka pūʻulu mana.

Ka nui o ka maʻi maʻi umauma
(Ke kiʻi ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)

ʻO ka awelika helu o nā maʻi koko ma ka ʻili o kēlā me kēia ʻiole i ka pule he 17 ma hope o ka ʻai ʻana i nā carcinogens
(Ke kiʻi ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)

ʻO ka manawa e ulu ai nā ʻiole ma hope o ka ʻai ʻana i nā carcinogens
(Ke kiʻi ʻia e Wu Tingyao, kumu ʻikepili / Mutat Res. 2017; 813: 45-51.)

Loaʻa iā Ganoderma lucidum triterpenes nā pono palekana a maikaʻi hoʻi.

ʻO nā hopena o nā hoʻokolohua holoholona ʻelua i hōʻike maopopo ʻia iā mākou inā paha ka hoʻokele waha a i ʻole ka hoʻohana ʻana i waho o Ganoderma lucidum total triterpenes hiki ke hoʻohaʻahaʻa maikaʻi i ka ulu ʻana o nā maʻi koko, hoʻemi i ka nui o nā maʻi koko a hoʻopaneʻe i ke ʻano o nā ʻōpū.

ʻO ke ʻano o ka Ganoderma lucidum total triterpenes e pili ana i ka hoʻoponopono ʻana i nā genes a me nā molekele protein i loko o nā pūnaʻi tumora i ʻōlelo ʻia ma mua o kēia ʻatikala.Ua hōʻoia mua ka hui noiʻi ʻaʻole e hōʻino nā Ganoderma lucidum total triterpenes i nā cell maʻamau, e hōʻike ana he palekana a maikaʻi hoʻi ka Ganoderma lucidum total triterpenes.

I loko o kēia hui hou i piha i nā pilikia olakino, he mea noʻonoʻo ke pale aku i nā carcinogens.Pehea e noi ai i nā pōmaikaʻi i nā manawa pilikia?ʻO nā huahana i loaʻa iā Ganoderma lucidum total triterpenes kāu meaʻai maikaʻi loa.

[Kumu] Smina TP, et al.ʻO Ganoderma lucidum ka nui o nā triterpenes e hoʻoulu i ka apoptosis i loko o nā pūnaewele MCF-7 a hoʻemi i ka DMBA i hoʻokomo ʻia i ka mammary a me ka ʻili carcinomas i nā holoholona hoʻokolohua.ʻO Mutat Res.2017;813: 45-51.
No ka mea kākau/ Ms. Wu Tingyao

Ke hōʻike nei ʻo Wu Tingyao i ka ʻike Ganoderma lima mua mai 1999. ʻO ia ka mea kākau o Healing with Ganoderma (i paʻi ʻia ma The People's Medical Publishing House ma ʻApelila 2017).

★ Ua paʻi ʻia kēia ʻatikala ma lalo o ka mana kūʻokoʻa o ka mea kākau.★ ʻAʻole hiki ke paʻi hou ʻia nā hana i luna, ʻokiʻoki a hoʻohana ʻia ma nā ʻano ʻē aʻe me ka ʻole o ka ʻae ʻia e ka mea kākau.★ No ka uhaki ʻana i ka ʻōlelo ma luna, e ʻimi ka mea kākau i nā kuleana pili kānāwai.★ Ua kākau ʻia ka kikokikona kumu o kēia ʻatikala ma ka ʻōlelo Pākē e Wu Tingyao a unuhi ʻia i ka ʻōlelo Pelekania e Alfred Liu.Inā loaʻa kekahi ʻokoʻa ma waena o ka unuhi (English) a me ka unuhi mua (Pake), e lanakila ka Pākē mua.Inā he nīnau ka poʻe heluhelu, e ʻoluʻolu e kelepona i ka mea kākau kumu, ʻo Ms. Wu Tingyao.