Ib txoj kev tshawb fawb luam tawm nyob rau hauv "Pharmacological Research" los ntawm Lub Xeev Lub Tsev Haujlwm Tseem Ceeb ntawm Kev Tshawb Fawb Suav Tshuaj Zoo Tshaj Plaws ntawm University of Macau (tus sau cov ntaub ntawv tshawb fawb) thiab ntau lub tsev tshawb fawb hauv tsev thaum Lub Yim Hli 2020 pom:

Ntxiv cov nas nrog Ganoderma lucidum spore roj (800 mg / kg) txhua hnub rau 27 hnub sib law liag tuaj yeem txhim kho lub peev xwm ntawm phagocytic ntawm macrophages thiab toxicity ntawm natural killer cells (NK cells).

Macrophages thiab natural killer cells yog cov protagonists ntawm "innate immune teb".Lawv lub luag haujlwm hauv kev tiv thaiv kab mob yog zoo li cov tub ceev xwm tub ceev xwm saib xyuas thiab tswj kev txiav txim hauv tib neeg lub ntiaj teb.Lawv tuaj yeem hais tau ua ntej ntawm kev tiv thaiv ntau yam kab mob, kab mob, thiab qog nqaij hlav cancer.

Yog li ntawd, cov lus teb muaj peev xwm ntawm macrophages thiab cov cell killer ntuj yuav nce ntxiv nrog cov roj spores, uas tuaj yeem ua rau muaj kev tiv thaiv kab mob los tua ntau yam "cov yeeb ncuab tsis pom".

Vim li cas cov roj spore txhim kho kev tiv thaiv?Nws yog ze ze rau cov kab mob plab hnyuv.

Cov hnyuv tau faib nrog ntau lub cev tiv thaiv kab mob thiab tseem muaj txhua yam kab mob.Kev noj zaub mov txawv yuav ua kom muaj zog lossis tsis muaj zog ntau hom kab mob hauv plab, thiab qhov sib txawv ntawm cov kab mob hauv plab hnyuv thiab cov metabolites uas tsim los ntawm ntau hom kab mob plab hnyuv yuav cuam tshuam rau kev taw qhia thiab qib ntawm kev tiv thaiv kab mob.

Raws li kev txheeb xyuas ntawm cov ntaub ntawv tshawb fawb no, tom qab nas tau noj cov roj spores rau ib lub sijhawm, cov khoom xyaw thiab cov metabolites ntawm lawv cov hnyuv yuav hloov, xws li:

Kev nce ntawm cov kab mob uas muaj txiaj ntsig zoo xws li Lactobacillus, txo qis ntawm cov kab mob phem xws li Staphylococcus thiab Helicobacter, thiab kev hloov pauv ntawm ntau tshaj li kaum hom kab mob metabolites xws li dopamine thiab L-threonine kom muaj nuj nqis.

Cov kev hloov pauv no muaj txiaj ntsig zoo los txhawb phagocytosis ntawm macrophages thiab txhim kho cov peev xwm tua neeg ntawm cov hlwb.

Ob peb xyoos dhau los, ntau cov kev tshawb fawb tau ua pov thawj tias kev tiv thaiv kev tiv thaiv ntawm Ganoderma lucidum fruiting lub cev extract thiab spore hmoov muaj feem xyuam rau cov kev cai ntawm cov hnyuv thiab nws cov metabolites.Niaj hnub no, kev tshawb fawb thaum kawg tau ua qhov sib txawv ntawm qhov nam ntawm cov roj spore.

Txawm hais tias nce kev ua yeeb yam ntawm macrophages thiab cov neeg tua neeg tuaj yeem ua rau muaj kev tiv thaiv kab mob hauv tsev tiv thaiv kab mob, xws li lub cev tsis muaj kab tiv thaiv kabmob (xws li cov hlwb ntawm sab hauv ntej) thiab nrhiav tau Cov tswv cuab tiv thaiv kab mob (xws li T hlwb, B hlwb thiab cov tshuaj tiv thaiv kab mob).

Txij li thaum cov extract, spore hmoov thiab spore roj ntawm Ganoderma lucidum muaj lawv tus kheej zoo hauv kev tswj kev tiv thaiv kab mob, vim li cas ho tsis siv lawv ib txhij los ua kom muaj feem cuam tshuam rau "tus yeeb ncuab tsis pom"?

[Data Resource] Xu Wu, et al.Ib qho kev sib xyaw microbiome thiab metabolomic tsom xam txheeb xyuas cov yam ntxwv ntawm kev tiv thaiv kab mob ntawm Ganoderma lucidum spores roj hauv cov nas.Pharmacol Res.Peb 2020, 158:104937.doi: 10.1016/j.phrs.2020.104937.

Hais txog tus sau/ Ms. Wu Tingyao
Wu Tingyao tau tshaj tawm cov ntaub ntawv Ganoderma lucidum thawj zaug txij li xyoo 1999. Nws yog tus sau "Ganoderma lucidum: Ingenious Beyond Description" (tshaj tawm hauv Lub Tsev Kho Mob Cov Neeg Kho Mob thaum Lub Plaub Hlis 2017).
 

★ Kab lus no tau luam tawm raws li kev tso cai tshwj xeeb ntawm tus sau, thiab cov tswv cuab yog GANOHERB ★ Cov haujlwm saum toj no tsis tuaj yeem luam tawm, txiav tawm lossis siv lwm txoj hauv kev yam tsis tau tso cai ntawm GanoHerb ★ Yog tias cov haujlwm tau tso cai siv, lawv yuav tsum tau siv nyob rau hauv lub Scope ntawm kev tso cai thiab qhia lub hauv paus: GanoHerb ★ Ua txhaum ntawm cov lus saum toj no, GanoHerb yuav ua raws li nws cov luag hauj lwm raws li txoj cai