February 9, 2017/Chung Shan Medical University/Pharmaceutical Biology

Umbhalo/WuTingyao

Kumuntu onempilo, ingabe ukhona umehluko phakathi kokudlaI-Ganoderma lucidumfuthi bengadliI-Ganoderma lucidum?Noma ngenye indlela, ingabe abantu abanempilo enhle badinga ukudlaI-Ganoderma lucidum?

NgoFebhuwari 2017, ithimba labacwaningi eliholwa nguProfesa Chin-Kun Wang waseChung Shan Medical University lishicilele umbiko wocwaningo lomtholampilo ku-"Pharmaceutical Biology", okufanele sibhekisele kuyo.

Amaphilisi e-Ganoderma lucidum asetshenziswe kulolu cwaningo ngalinye linesisindo esingama-225 mg, futhi okuqukethweI-Ganoderma lucidumi-fruiting body extract, equkethe u-7% wama-ganoderic acid (okuhlanganisa i-ganoderic acid A, B, C, C5, C6, D, E no-G) ​​kanye nama-peptide e-polysaccharide angu-6%.Okuqukethwe kwe-capsule ye-placebo ngu-90% isitashi no-10%I-Ganoderma lucidumkhipha izinsalela, ezibukeka njengeI-Ganoderma lucidumi-capsule.

Abacwaningi baqasha amavolontiya angu-42 (amadoda angu-22 nabesifazane abangu-20) abaneminyaka engu-40 kuya kwengama-54 ababenempilo enhle iyonke ngaphandle kwabambalwa ababene-GOT noma i-GPT ephakeme noma isibindi esinamafutha amancane noma i-polyp ye-gallbladder.

Bahlukaniswa ngamaqembu amabili "ukuhlolwa kwe-double blind-blind crossover": iqembu elilodwa lathatha i-placebo, kanti elinye iqembu lathatha i-placebo.I-Ganoderma lucidumamaphilisi (1 capsule ngosuku ngemva kwesidlo sasemini noma isidlo sakusihlwa) izinyanga eziyisithupha.Ngemuva kwalokho, zonke izifundo zingene "esikhathini sokugeza" (akukho placebo nomaI-Ganoderma lucidum).Ngemva kwenyanga, labo abathathaI-Ganoderma lucidumyashintsha yaba yi-placebo, futhi labo abathatha i-placebo bashintsha babaI-Ganoderma lucidum.Zombili zahlala izinyanga eziyisithupha.

I-Ganoderma lucidumkuthuthukisa umthamo we-antioxidant.

Ngalo mklamo wokuhlola, umehluko phakathi “kokudlaI-Ganoderma lucidum” kanye “nokudla i-placebo” kungabonwa ngokulandelana esihlokweni esifanayo.Ekugcineni, bangu-39 sebebonke abaphothule ukuhlolwa.Kutholwe ukuthi awukho umehluko omkhulu ngobude, isisindo, amafutha omzimba kanye ne-body mass index (BMI) yezifundo kungakhathaliseki ukuthi ziyathatha.I-Ganoderma lucidumnoma i-placebo.

Nokho, ukwaziswa kukalwa ngegazi lezifundo kubonisa ukuthi ukudlaI-Ganoderma lucidumisigamu sonyaka kungandisa kakhulu i-Trolox-equivalent antioxidant capacity (TEAC), kanye nokuqukethwe kanye nomsebenzi we-antioxidant enzymes, futhi kunciphise kakhulu umonakalo oxidative kuma-cell membranes kanye ne-DNA;Ngokuphambene, i-placebo ayizange ilethe ushintsho olungako (bona ithebula elingezansi).

Ama-enzyme e-antioxidant kumangqamuzana egazi abomvu nawo ayinkomba ebalulekile ye-antioxidant enamandla-amangqamuzana egazi abomvu anesibopho sokuthutha ama-molecule omoya-mpilo asengozini enkulu yokulimala kwe-oxidative, futhi izindlela zawo zokuzivikela zibaluleke nakakhulu.Imiphumela yokuhlola nayo ikhombisa lokhoI-Ganoderma lucidumingakhuphula kakhulu okuqukethwe kwama-enzyme ahlukahlukene e-antioxidant kumaseli abomvu egazi (bheka ithebula elingezansi).

Ihlungwe nge-/Wu Tingyao (Umthombo / I-Pharm Biol. 2017 Dec;55(1):1041-1046.)

I-Ganoderma lucidumisiza ukuvikela isibindi.

Ngaphezu kwalokho,I-Ganoderma lucidumyehlise isilinganiso sezifundo se-GOT ne-GPT ngo-42% no-27%, ngokulandelana.I-Ultrasound yesisu iphinde yabonisa ukuthi izimpawu zezifundo ezintathu ezazinoshukela wokuqala wesibindi noma i-gallbladder polyp zicishe zabuyela kwesijwayelekile ngemuva kokwelashwaI-Ganoderma lucidum(njengoba kukhonjisiwe emfanekisweni ongezansi).

Isithombe (A), Isithombe (B), Isithombe (C) yizithombe ze-abdominal ultrasonography zezifundo No. 10, No. 19 kanye No. 36, ngokulandelana.Laba ababili bokuqala banesibindi esinamafutha amancane, kanti laba bangaphambili bane-polyp ye-gallbladder.Ngemva kokudlaI-Ganoderma lucidumizinyanga eziyisithupha, izimpawu zokuqala zazicishe zingabonakali ezithombeni ze-ultrasound zesisu (isithombe (D), isithombe (E), isithombe (F) ngokulandelana).

(Umthombo wedatha/I-Pharm Biol. 2017 Dec;55(1):1041-1046.)

I-Ganoderma lucidumithuthukisa impilo.

Imiphumela engenhla ikhombisa lokhoI-Ganoderma lucidumingathuthukisa i-anti-oxidation, ithuthukise ukusebenza kwesibindi futhi ilungise ukulimala kwesibindi kubantu abanempilo.Njengoba "i-oxidation" ingenye yemithombo "yokuguga", imiphumela yalolu cwaningo nayo inokubaluleka kokulwa nokuguga.

Ake sibone ukuthi yimaliniI-Ganoderma lucidumzadla lezi zifundo.I-capsule eyodwa kuphela ngosuku!Inqobo nje uma uqhubeka nokudla inani elincane (225 mg) likaI-Ganoderma lucidumkhipha, ungathuthukisa impilo yakho kakade enhle.Kungani kungenjalo?Kuyonga kakhulu kunokubuzaI-Ganoderma lucidumukuze uthole usizo ngemva kokugula.Vele, isisekelo siwukuthi i-Ganoderma lucidum oyidlayo kufanele okungenani icebile ngama-triterpenes nama-polysaccharidesI-Ganoderma lucidumisetshenziswe kulesi sivivinyo somtholampilo!

[Umthombo] Chiu HF, et al.I-Triterpenoids kanye ne-polysaccharide peptides-enothisiwe i-Ganoderma lucidum: isifundo se-placebo esilawulwa ngokungahleliwe, esiyimpumputhe esiphindwe kabili se-antioxidation nokusebenza kwe-hepatoprotective kumavolontiya anempilo.I-Pharm Biol.2017;55(1):1041-1046.doi: 10.1080/13880209.2017.1288750.

PHELA

Mayelana nombhali/ Nks. Wu Tingyao
UWu Tingyao ubelokhu ebika ngolwazi lwe-Ganoderma lokuqala kusukela ngo-1999. Ungumbhali wencwadiUkwelapha nge-Ganoderma(ishicilelwe ku-People's Medical Publishing House ngo-Ephreli 2017).
 
★ Lesi sihloko sishicilelwe ngaphansi kokugunyazwa okukhethekile kombhali.★ Le misebenzi engenhla ayinakuphinda ikhiqizwe, ikhishwe noma isetshenziswe ngezinye izindlela ngaphandle kwemvume yombhali.★ Ngokuphulwa kwesitatimende esingenhla, umbhali uzolandela izibopho ezingokomthetho ezifanele.★ Umbhalo wokuqala walesi sihloko ubhalwe ngesiShayina nguWu Tingyao futhi wahunyushelwa esiNgisini ngu-Alfred Liu.Uma kukhona ukungqubuzana phakathi kokuhumusha (isiNgisi) kanye nokwangempela (isiShayina), isiShayina sangempela siyonqoba.Uma abafundi benemibuzo, sicela uthinte umbhali wokuqala, uNksz. Wu Tingyao.