Umthombo wesithombe / Iwebhusayithi esemthethweni Yenhlangano Yezempilo Yomhlaba

Ngenkulumo-ze “yohlanga lwegciwane,” i-WHO ikhumbuze sonke isintu ngemfudumalo ukuthi ezinye izinhlobo zenoveli coronavirus “zigijima” ngokushesha futhi kulula ukusakazeka phakathi kwabantu kunamanye ama-coronavirus amasha.Kepha noma ngabe igciwane eligijima ngokushesha noma elihamba kancane, indlela yokubavimba ukuthi bangangitholi mina nawe iyafana: geza izandla njalo, gqoka imaskhi, ugcine ukuqhelelana komphakathi, futhi ugweme ukuhlangana ngamaqembu.

Ngaphandle kwalezi zindlela zokuphepha eziyisisekelo, yiziphi ezinye izindlela “ezithembeke ngempela,” “okulula ukuzithola,” kanye “ezilula ukuzisebenzisa” zokuthuthukisa amandla ethu ukuze sihlale phambili kulo mjaho we-hill-by-hill?Yini esingayenza ukuze sengeze ungqimba olwengeziwe lwesivikelo ukuze sinciphise umonakalo ngisho noma singenwe igciwane ngephutha?

Kube nemibiko eminingana yocwaningo noma amaphepha okubukeza ashicilelwe kumajenali omhlaba, akhombisa ukuthi “I-Ganoderma lucidum", ecebile ngama-polysaccharides, ama-triterpenes namaprotheni avikela umzimba, kufanele asisize silwe ne-coronavirus yenoveli.

Ephreli 2020 - Ijenali Yemolekyuli:I-Ganoderma luciduminakho kokubili i-anti-virus kanye nezingxenye ezilawula amasosha omzimba

Ngo-Ephreli 2020, ososayensi baseNyuvesi yaseChiang Mai kanye neRoyal Academy of Sciences yaseThailand bashicilela iphepha lokubheka emuva kumaMolekuli.

Ngokusekelwe emiphumeleni yocwaningo eyaziwayo njengamanje, bahlole “amasheya angaba khona” angase avimbele i-SARS, i-MERS, i-COVID-19 namanye ama-coronavirus ezithako eziningi zesikhunta ngenhloso “yokuvimbela ukuphindaphindeka kwegciwane” kanye “nokulawula ukuphendula kwamasosha omzimba”.Ngenxa yalokho, ama-polysaccharides, ama-triterpenoids, nama-protein immunomodulatory avelaI-Ganoderma lucidumbonke babalwe phakathi kwabo.

Njengoba amagciwane kufanele athembele kumaseli ukuze aphile futhi ande, lokho okubizwa ngokuthi “i-anti-virus” imiphumela imayelana “nokuphazamisa inqubo yokuphindaphindeka kwegciwane engqamuzaneni”, okwenza kube nzima ngegciwane ukukhiqiza amagciwane amaningi ngengqamuzana. .

Ngokuqondene nalawo magciwane asafuna okuhlosiwe ngaphandle kwengqamuzana - kungakhathaliseki ukuthi igciwane elisanda kuhlasela umzimba noma igciwane elisha elisanda kukhishwa esitokisini - la magciwane azoqedwa ekuphenduleni kokuvuvukala kwamasosha omzimba.Ngemuva kokuthi igciwane selisuliwe, ukuthi impendulo yokuvuvukala ingaqedwa ngokushesha ngangokunokwenzeka ukuze kugwenywe ukulimala kwamaseli ajwayelekile nakho kuncike ekulawuleni amasosha omzimba.

Ngakho-ke,I-Ganoderma lucidum, enezingxenye ezivimbela ukuphindaphinda kwegciwane futhi ilungise amasosha omzimba, ibonakala iyifomula yemvelo ye-cocktail yokuvimbela nokwelapha amagciwane, ehlinzeka ngomshwalense ophindwe kabili okufanele ubheke phambili ekunciphiseni usongo lwama-coronavirus kuhlanganise ne-coronavirus yenoveli.

Juni 2020- "Ijenali YaseShayina Ye-Pharmacology and Toxicology": Umphumela weI-Ganodermalucidumekuqiniseni amandla abalulekile kanye nokuqeda izici ze-pathogenic kanye nomphumela wayo we-antiviral

Ngokufana nemibono yezazi zaseThailand, uSolwazi Zhi-Bin Lin wasePeking University uphinde washicilela iphepha ku-Chinese Journal of Pharmacology and Toxicology ngoJuni 2020, exoxa ngamathuba okuvikela nokwelapha i-COVID-19I-Ganoderma lucidumkusukela kokubili umbono we-TCM ekuqiniseni amandla abalulekile nokuqeda izici ze-pathogenic kanye nombono womuthi wasentshonalanga ku-anti-virus.

February 2021-Izinqubo zeNational Academy of Sciences: I-Ganoderma polysaccharides inganciphisa inani le-coronavirus yenoveli emaphashini ezilwane.

Umbiko oshicilelwe yiqembu le-Taiwan Academia Sinica e-PNAS (Izinqubo ze-National Academy of Sciences) ngoFebhuwari 2021 ukuqinisekisile lokho:

Esinye sezithako eziyinhloko ezisebenzayo kuI-Ganoderma lucidum,"I-Ganoderma lucidum polysaccharides", ingaba yi-antiviral kokubili ku-vitro kanye ne-vivo, inikeza ubufakazi obuqondile besayensi bokuthiI-Ganoderma lucidumisiza ukuvimbela kanye nokwelapha inoveli coronavirus.

Okokuqala, ukuhlolwa kwe-in vitro, abacwaningi baqala ukwenza amaseli e-Vero E6 futhiI-Ganoderma lucidumi-polysaccharide extract (igama lekhodi RF3) ndawonye, ​​bese wengeza i-coronavirus yenoveli ukuze kubonwe inani lokuphindaphinda kwegciwane kanye nokusinda kwamaseli ngemuva kwamahora angama-48.

Njengoba sonke sazi, i-coronavirus yenoveli ihlasela umzimba womuntu ngesamukeli se-ACE2 esitokisini.Amaseli e-Vero E6 avela esicutshini sezinso zezinkawu eziluhlaza zase-Afrika angaveza inani elikhulu lama-receptors e-ACE2, ngakho-ke lapho ehlangana ne-coronavirus yenoveli, leli gciwane lingangena kalula kumaseli ukuze liphindaphindeke futhi lande.

Imiphumela yabonisa ukuthiI-Ganoderma lucidumukukhishwa kwe-polysaccharide kunganciphisa inani lokuphindaphinda kwegciwane kuhhafu ekuhlanganiseni okuphansi kwe-2μg/mL ngaphandle kokubangela ukufa kweseli.

Abacwaningi base benza izivivinyo zezilwane: baqale bathelela ama-hamster nge-coronavirus yenoveli base belawulaI-Ganoderma lucidumi-polysaccharide ikhishwa ngomlomo kuma-hamster ngethamo lansuku zonke lama-200 mg/kg izinsuku ezintathu.

Kutholakale ukuthi inani legciwane emaphashini ama-hamster lalicishe libe yingxenye yeqembu elingaphathwanga (amanzi anikezwe), futhi isisindo sama-hamster sahlala sisezingeni elifanayo nangaphambi kokutheleleka ngaphandle kokunyuka okubukhali noma ukwehla.Lokhu kusho ukuthi i-I-Ganoderma lucidumUkukhishwa kwe-polysaccharide akukwazi nje ukuvimbela ngempumelelo ukukhula kwe-coronavirus yenoveli kuma-hamster kodwa futhi kunezinga eliphezulu lokuphepha okudliwayo.

Akulula ngempela lokhoI-Ganoderma lucidumama-polysaccharides angagqama kulolu cwaningo.Ngoba lokhu kuwumphumela wokuqhathanisa nezidakamizwa zabantu noma zezilwane eziyi-2,855 ezigunyazwe i-US Food and Drug Administration (FDA) kanye nezingcaphuno zamanzi ezicishe zibe ngu-200 zemithi yemithi yaseShayina esebenza ngempumelelo ekwelapheni izifo ezibangelwa amagciwane.

Ekugcineni,I-Ganoderma lucidumama-polysaccharides ukuphela kwezakhi zokwelapha ezingaba nemiphumela elwa namagciwane emzimbeni ngaphandle kokubangela ukufa kwamangqamuzana noma ukuncipha kwesisindo.

Ngaphezu kwalokho, i-polysaccharides ingenye yezithako ezisebenzayoI-Ganoderma lucidum.Uma kokubili ama-polysaccharides nama-triterpenoid e-Ganoderma lucidum engezwa ukulwa naleli gciwane, kuzokwenzekani?

Meyi 2021-"I-International Journal of Medicinal Fungi":I-Ganoderma lucidumukulinganisa umphumela usiza ukululama futhi ugwema ukugula okunzima

NgoMeyi 2021, ngenxa yezimpawu ze-pneumonia kanye noshintsho lwemithambo yegazi olubangelwa inoveli coronavirus, iphepha lokubuyela emuva elishicilelwe ku- "International Journal of Medicinal Mushrooms" yizazi ezivela eMnyangweni we-Biochemistry kanye ne-Molecular Biology yase-Jahangirnagar University e-Bangladesh kanye ne-Agricultural. I-Extension Division Mushroom Development Research Institute yoMnyango Wezolimo wase-Bangladesh ihlaziye ukuthi kungenzeka yini izinhlobonhlobo zezithako ezisebenzayo zesikhunta ukwelapha nokuvimbela ukugula okunzima futhi yaphetha ngokuthi.I-Ganoderma lucidumkubonakala kuwumuthi ofaneleka kakhulu kubo bonke abantu ukulwa ne-COVID-19 phakathi kwezinhlobo ezihlukahlukene zamakhowe.

Ukuze iziguli ezine-novel pneumonia ye-coronary zilulame endaweni yezempilo kunokuba zibe zimbi kakhulu zibheke isifo esibi, kubonakala sengathi kuphelaI-Ganoderma lucidum, ecebile ngezinhlobonhlobo zezithako ezisebenzayo, ingcono kakhulu ekugcineni ibhalansi phakathi kwe-ACE (Angiotensin Converting Enzyme) ne-ACE2 (Angiotensin Converting Enzyme 2) kanye nebhalansi phakathi kokuthuthukisa ukusabela komzimba (anti-viral) nokucindezela ukuvuvukala. impendulo (ukuvikela amaseli).

February 2020-China Nutrition and Health Food Association:I-Ganoderma lucidumkungasiza ukuvikela nokwelapha izifo ezintsha ze-coronavirus

"Isihloko sesibili esidumile sochungechunge lwesayensi mayelana nosizo olunembile ekuvimbeleni nasekwelapheni ukutheleleka okusha kwe-coronavirus mayelana nokudla okunomsoco - umsebenzi wezithako zokudla okunomsoco" eshicilelwe yi-China Nutrition and Health Food Association yamemezela emphakathini izinhlobo eziyi-12 zezithako zokudla okunomsoco ezisiza ukuvimbela. futhi welaphe inoveli coronavirus, okuhlanganisaI-Ganoderma lucidum.

I-athikili yaveza ngokucacile:I-Ganoderma luciduminomphumela ovuselela umzimba, ongathinta ngokuqondile amandla ayo okulwa nezifo ezibangelwa amagciwane kanye negciwane.

Kubonakala sengathi umjaho phakathi kwabantu ne-coronavirus yenoveli ngeke uphele ngesikhathi esifushane.Igciwane le-mutant eligijima ngokushesha alibonakali kuyi-Delta yodwa.

Uma ufuna ukuqhubeka ungabanjwa yigciwane, yidla kakhuluI-Ganoderma lucidumlokho “kugunyazwe ngokwesayensi”!I-Ganoderma lucidum, elandelekayo, ephephile, enokwethenjelwa futhi equkethe ama-polysaccharides nama-triterpenes, akufanele ikuvumele phansi.

[Umthombo Wedatha]

1. Suwannarach N, et al.Ama-Natural Bioactive Compounds avela ku-Fungi Njengabangase Bangenele ama-Protease Inhibitors kanye nama-Immunomodulators ukuze bafake isicelo seCoronavirus.Amangqamuzana.2020, 25(8): 1800. doi:10.3390/molecules25081800.

2. Zhi-Bin Lin.Ukuqinisa amandla abalulekile kanye nokuqeda izici ze-pathogenic kanye nomphumela we-antiviral we-Ganoderma lucidum.I-Chinese Journal of Pharmacology kanye ne-Toxicology.2020;34(6): 401-407.

3. Jia-Tsrong Jan, et al.Ukuhlonzwa Kwemithi Ekhona kanye Nemithi Yekhambi Njengama-Inhibitors we-SARS-CoV-2 Infection.I-Proc Natl Acad Sci US A. 2021 Feb 2;118(5):e2021579118.doi: 10.1073/pnas.2021579118.

4. U-Mohammad Azizur Rahman, et al.Ukulungiswa Kwezindlela Zokuvimbela Nezokwelapha Ezisekelwe Kumakhowe ku-COVID-19: Buyekeza.I-Int J Med Mushrooms.2021;23(5):1-11.doi: 10.1615/IntJMedMushrooms.2021038285.

PHELA 

Mayelana nombhali/ Nks. Wu Tingyao

UWu Tingyao ubelokhu ebika ngolwazi lokuqala lwe-Ganoderma lucidum kusukela ngo-1999. Ungumbhali wencwadiUkwelapha nge-Ganoderma(ishicilelwe ku-People's Medical Publishing House ngo-Ephreli 2017).

★ Lesi sihloko sishicilelwe ngaphansi kokugunyazwa okukhethekile kombhali, futhi ubunikazi bungeka-GANOHERB ★ Le misebenzi engenhla ayinakuphinda ikhiqizwe, ikhishwe noma isetshenziswe ngezinye izindlela ngaphandle kokugunyazwa kwe-GanoHerb ★ Uma imisebenzi igunyaziwe ukuthi isetshenziswe, kufanele isetshenziswe ngaphakathi kobubanzi bokugunyazwa futhi ibonise umthombo: GanoHerb ★ Kunoma yikuphi ukwephulwa kwesitatimende esingenhla, i-GanoHerb izophishekela izibopho zomthetho ezihlobene ★ Umbhalo wokuqala wale ndatshana ubhalwe ngesiShayina nguWu Tingyao futhi wahunyushelwa esiNgisini ngu-Alfred. U-Liu.Uma kukhona ukungqubuzana phakathi kokuhumusha (isiNgisi) kanye nokwangempela (isiShayina), isiShayina sangempela siyonqoba.Uma abafundi benemibuzo, sicela uthinte umbhali wokuqala, uNksz. Wu Tingyao.

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