Gwero la zithunzi / tsamba lovomerezeka la World Health Organisation

Kudzera m'mabodza a "mtundu wa ma virus", WHO idakumbutsa anthu onse mwachikondi kuti mitundu ina ya buku la coronavirus "imatha" mwachangu ndipo ndiyosavuta kufalikira pakati pa anthu kuposa ma coronavirus ena atsopano.Koma kaya ndi kachilombo komwe kamayenda mwachangu kapena pang'onopang'ono, njira yowaletsera kuti asakupezeni inu ndi ine ndiyofanana: sambani m'manja pafupipafupi, valani chigoba, khalani ndi malo ochezera, ndipo pewani kusonkhana m'magulu.

Kupatula njira zodzitetezera izi, ndi njira ziti “zodalirika,” “zosavuta kuzipeza,” ndi “zosavuta kuzitsatira” zomwe zingatithandize kulimbikitsa mphamvu zathu kuti tipite patsogolo pa mpikisano wothamanga wa mapiri ndi mapiri?Kodi tingatani kuti tiwonjezere chitetezo china kuti tichepetse kuwonongeka ngakhale titatenga kachilomboka mwangozi?

Pakhala pali malipoti angapo ofufuza kapena zolemba zowunikira zomwe zidasindikizidwa m'magazini apadziko lonse lapansi, zomwe zikuwonetsa kuti "Ganoderma lucidum", yomwe ili ndi ma polysaccharides, triterpenes ndi mapuloteni oteteza thupi ku chitetezo chathupi, iyenera kutithandiza kulimbana ndi coronavirus yatsopano.

Epulo 2020 - Journal of Molecule:Ganoderma lucidumali ndi zida zonse zotsutsana ndi ma virus komanso chitetezo chamthupi

Mu Epulo 2020, asayansi ochokera ku Yunivesite ya Chiang Mai ndi Royal Academy of Sciences of Thailand adasindikiza pepala loyang'ana m'ma Molecules.

Kutengera zotsatira za kafukufuku zomwe zadziwika pano, adawunika "masheya omwe angatheke" omwe angalepheretse SARS, MERS, COVID-19 ndi ma coronavirus ena kuchokera kuzinthu zambiri za mafangasi ndi cholinga "choletsa kuchulukitsa kwa ma virus" komanso "kuwongolera kuyankha kwa chitetezo chathupi".Zotsatira zake, ma polysaccharides, triterpenoids, ndi mapuloteni a immunomodulatory kuchokeraGanoderma lucidumonse alembedwa mwa iwo.

Popeza ma virus amayenera kudalira ma cell kuti apulumuke ndikuchulukirachulukira, zomwe zimatchedwa "anti-virus" zimangokhudza "kusokoneza kagayidwe ka kachilomboka muselo", zomwe zimapangitsa kuti zisatheke kuti kachilomboka katulutse ma virus ambiri kudzera mu selo. .

Ponena za ma virus omwe akuyang'anabe zomwe akufuna kunja kwa cell - kaya ndi kachilombo komwe kangolowa m'thupi kapena kachilombo komwe kangotulutsidwa kumene muselo - ma virus awa achotsedwa pakuyankha kwa chitetezo chamthupi.Pambuyo pochotsa kachilomboka, ngati kuyankha kotupa kumatha kuthetsedwa posachedwa kuti tipewe kuwonongeka kwa maselo abwinobwino zimadaliranso kuwongolera chitetezo chamthupi.

Chifukwa chake,Ganoderma lucidum, yomwe ili ndi zigawo zomwe zimalepheretsa kubwereza kwa ma virus ndikusintha chitetezo chamthupi, zikuwoneka ngati njira yachilengedwe yopewera ndikuchiritsa ma virus, kupereka inshuwaransi iwiri yomwe ikuyenera kuyembekezera kuchepetsa chiwopsezo cha ma coronavirus kuphatikiza buku la coronavirus.

June 2020- "Chinese Journal of Pharmacology and Toxicology": Zotsatira zaGanodermalucidumpolimbitsa mphamvu zofunikira ndikuchotsa zinthu zoyambitsa matenda komanso zotsatira zake zowononga ma virus

Mofanana ndi malingaliro a akatswiri aku Thailand, Pulofesa Zhi-Bin Lin waku Peking University adasindikizanso pepala mu Chinese Journal of Pharmacology and Toxicology mu June 2020, kukambirana za kuthekera kopewa ndi kuchiza COVID-19Ganoderma lucidumkuchokera pamalingaliro a TCM pakulimbitsa mphamvu zofunikira ndikuchotsa zinthu zoyambitsa matenda komanso malingaliro amankhwala akumadzulo mu anti-virus.

February 2021-Zomwe zikuchitika ku National Academy of Sciences: Ganoderma polysaccharides imatha kuchepetsa kuchuluka kwa ma coronavirus m'mapapu a nyama.

Lipoti lofalitsidwa ndi gulu la Taiwan Academia Sinica ku PNAS (Proceedings of the National Academy of Sciences) mu February 2021 linatsimikizira kuti:

Chimodzi mwazinthu zomwe zimagwira ntchito muGanoderma lucidum,"Ganoderma lucidum polysaccharides", itha kukhala antiviral onse mu vitro komanso mu vivo, kupereka umboni wachindunji wa sayansi kutiGanoderma lucidumimathandizira kupewa komanso kuchiza coronavirus yatsopano.

Choyamba, kuyesa kwa in vitro, ofufuzawo adakulitsa ma cell a Vero E6 ndiGanoderma lucidumpolysaccharide extract (code name RF3) palimodzi, kenako ndikuwonjezera buku la coronavirus kuti muwone kuchuluka kwa kachilombo kobwerezabwereza komanso kupulumuka kwa ma cell pakatha maola 48.

Monga tonse tikudziwa, buku la coronavirus limalowa m'thupi la munthu kudzera pa cholandilira cha ACE2 paselo.Ma cell a Vero E6 ochokera ku impso za anyani obiriwira aku Africa amatha kuwonetsa kuchuluka kwa ma ACE2 receptors, kotero akakumana ndi buku la coronavirus, kachilomboka kamatha kulowa m'maselo kuti abwereze ndikuchulukana.

Zotsatira zinawonetsa kutiGanoderma lucidumKutulutsa kwa polysaccharide kumatha kuchepetsa kuchuluka kwa kachilombo ka HIV mpaka theka pamlingo wochepa wa 2μg/mL popanda kuchititsa kufa kwa cell.

Ofufuzawo adayesa nyama: poyamba adapatsira ma hamster ndi buku la coronavirus kenako adaperekaGanoderma lucidumpolysaccharide Tingafinye pakamwa kwa hamsters pa tsiku mlingo wa 200 mg/kg kwa masiku 3.

Zinapezeka kuti kuchuluka kwa kachilombo ka HIV m'mapapo a hamster kunali pafupifupi theka la gulu losagwiritsidwa ntchito (madzi opatsidwa), ndipo kulemera kwa hamster kunakhalabe pamlingo womwewo monga matenda asanakhalepo popanda kuwonjezeka kwakukulu kapena kuchepa.Izi zikutanthauza kutiGanoderma lucidumKutulutsa kwa polysaccharide sikungalepheretse kukula kwa buku la coronavirus mu hamsters komanso kumakhala ndi chitetezo chokwanira.

Sizophweka kutiGanoderma lucidumma polysaccharides amatha kuonekera mu kafukufukuyu.Chifukwa izi ndi zotsatira za kuyerekeza ndi mankhwala a 2,855 a anthu kapena a nyama omwe amavomerezedwa ndi US Food and Drug Administration (FDA) ndi pafupifupi 200 amadzimadzi a mankhwala azitsamba achi China omwe amagwira ntchito pochiza matenda a virus.

Pomaliza,Ganoderma lucidumma polysaccharides ndi mankhwala okhawo omwe amatha kukhala ndi antivayirasi m'thupi popanda kuchititsa kufa kwa maselo kapena kuwonda.

Kuphatikiza apo, ma polysaccharides ndi amodzi mwazinthu zomwe zimagwira ntchitoGanoderma lucidum.Ngati ma polysaccharides ndi ma triterpenoids onse ku Ganoderma lucidum awonjezedwa kuti amenyane ndi kachilomboka, chimachitika ndi chiyani?

Meyi 2021-"International Journal of Medicinal Fungi":Ganoderma lucidum's kulinganiza zotsatira kumathandiza kuchira ndi kupewa matenda aakulu

Mu Meyi 2021, chifukwa cha zizindikiro za chibayo komanso kusintha kwa mitsempha chifukwa cha buku la coronavirus, pepala loyang'ana kumbuyo lomwe linasindikizidwa mu "International Journal of Medicinal Mushrooms" ndi akatswiri ochokera ku dipatimenti ya Biochemistry ndi Molecular Biology ya Jahangirnagar University ku Bangladesh ndi Agricultural. Extension Division Mushroom Development Research Institute ya Unduna wa Zaulimi ku Bangladesh idasanthula kuthekera kwa mitundu yosiyanasiyana ya bowa zomwe zimagwira ntchito pochiza komanso kupewa matenda oopsa ndipo adatsimikiza kuti.Ganoderma lucidumzikuwoneka ngati mankhwala oyenera kwambiri kuti anthu onse athe kulimbana ndi COVID-19 pakati pa mitundu yosiyanasiyana ya bowa.

Kwa odwala omwe ali ndi chibayo chodziwika bwino kuti achire kudera laumoyo m'malo mopitilira matenda oopsa, zikuwoneka kutiGanoderma lucidum, yomwe ili ndi zinthu zambiri zogwira ntchito, imakhala yabwino kwambiri pakusunga bwino pakati pa ACE (Angiotensin Converting Enzyme) ndi ACE2 (Angiotensin Converting Enzyme 2) komanso mgwirizano pakati pa kulimbitsa chitetezo cha mthupi (anti-viral) ndi kupondereza kutupa. kuyankha (kuteteza maselo).

February 2020-China Nutrition and Health Food Association:Ganoderma lucidumzitha kuthandiza kupewa ndi kuchiza matenda atsopano a coronavirus

"Nkhani yachiwiri yotchuka ya sayansi yokhudzana ndi chithandizo chenichenicho popewa komanso kuchiza matenda atsopano a coronavirus pankhani yazakudya - ntchito yazakudya zopatsa thanzi" yofalitsidwa ndi China Nutrition and Health Food Association idalengeza kwa anthu mitundu 12 yazakudya zomwe zimathandizira kupewa. ndikuchiritsa novel coronavirus, kuphatikizaGanoderma lucidum.

Nkhaniyo inanena momveka bwino kuti:Ganoderma lucidumali ndi chitetezo cha m'thupi, chomwe chingakhudze mwachindunji mphamvu yake yolimbana ndi matenda a bakiteriya ndi mavairasi.

Zikuwoneka kuti mpikisano pakati pa anthu ndi buku la coronavirus sudzatha pakanthawi kochepa.Kachilombo koyambitsa matenda komwe kamathamanga mwachangu sikuwoneka ngati Delta yokha.

Ngati mukufuna kukhala patsogolo osagwidwa ndi kachilomboka, idyani zambiriGanoderma lucidumndicho “chotsimikiziridwa mwasayansi”!Ganoderma lucidum, yomwe imapezeka, yotetezeka, yodalirika komanso imakhala ndi ma polysaccharides ndi triterpenes, sayenera kukukhumudwitsani.

[Magwero a Data]

1. Suwannarach N, et al.Natural Bioactive Compounds kuchokera ku Bowa monga Okhoza Kusankhidwa a Protease Inhibitors ndi Immunomodulators Kuti Alembetse Ma Coronaviruses.Mamolekyu.2020, 25 (8): 1800. doi: 10.3390 / mamolekyu25081800.

2. Zhi-Bin Lin.Kulimbitsa mphamvu zofunikira ndikuchotsa zinthu zoyambitsa matenda komanso antiviral effect ya Ganoderma lucidum.Chinese Journal of Pharmacology ndi Toxicology.2020;34 (6): 401-407.

3. Jia-Tsrong Jan, et al.Kuzindikiritsidwa kwa Mankhwala Omwe Alipo ndi Mankhwala Azitsamba Monga Zoletsa za SARS-CoV-2 Infection.Proc Natl Acad Sci US A. 2021 Feb 2;118(5):e2021579118.doi: 10.1073/pnas.2021579118.

4. Mohammad Azizur Rahman, et al.Kulinganiza Njira Zopewera ndi Zochizira Zotengera Bowa ku COVID-19: Ndemanga.Int J Med Bowa.2021;23(5):1-11.doi: 10.1615/IntJMedMushrooms.2021038285.

TSIRIZA 

Za wolemba/ Mayi Wu Tingyao

Wu Tingyao wakhala akufotokoza zambiri za Ganoderma lucidum kuyambira 1999. Iye ndi mlembi wa bukuli.Kuchiza ndi Ganoderma(lofalitsidwa mu The People's Medical Publishing House mu April 2017).

★ Nkhaniyi yasindikizidwa pansi pa chilolezo cha wolemba, ndipo umwini ndi wa GANOHERB ★ Ntchito zomwe zili pamwambazi sizingapangidwenso, kuchotsedwa kapena kugwiritsidwa ntchito m'njira zina popanda chilolezo cha GanoHerb ★ Ngati ntchitozo zaloledwa kugwiritsidwa ntchito, iwo ziyenera kugwiritsidwa ntchito mkati mwa chilolezo ndikuwonetsa gwero: GanoHerb ★ Pakuphwanya kulikonse kwa mawu omwe ali pamwambawa, GanoHerb idzatsatira maudindo okhudzana ndi zamalamulo ★ Zolemba zoyambirira za nkhaniyi zidalembedwa m'Chitchaina ndi Wu Tingyao ndikumasuliridwa m'Chingerezi ndi Alfred. Liu.Ngati pali kusiyana kulikonse pakati pa kumasulira (Chingerezi) ndi choyambirira (Chitchaina), Chitchaina choyambirira chidzapambana.Ngati owerenga ali ndi mafunso, lemberani wolemba woyamba, Mayi Wu Tingyao.

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