Isi iyi foto / webụsaịtị gọọmentị nke World Health Organisation

Site na mgbasa ozi “ọsọ nje”, WHO ji obi ụtọ chetara ihe a kpọrọ mmadụ na ụfọdụ ụdị coronavirus ọhụrụ “na-agba ọsọ” ngwa ngwa ma dịkwa mfe ịgbasa n'etiti ndị mmadụ karịa coronaviruse akwụkwọ akụkọ ndị ọzọ.Mana ma ọ bụ nje na-agba ọsọ ọsọ ma ọ bụ nwayọ, ụzọ ị ga-esi gbochie ha ịbịakwute mụ na gị bụ otu ihe ahụ: na-asa aka gị ugboro ugboro, na-ekpuchi ihe mkpuchi, na-adọpụ uche ọha na eze, ma zere izukọta n'ìgwè.

E wezụga mkpachapụ anya ndị a bụ isi, gịnị bụ ụfọdụ “a pụrụ ịdabere na ya,” “dị mfe inweta,” na “dị mfe itinye n'ọrụ” ụzọ isi kwalite ume anyị iji nọrọ n'ihu na marathon nke ugwu?Kedu ihe anyị nwere ike ime iji gbakwunye nchebe ọzọ ka anyị wee nwee ike ibelata mmebi ọ bụrụgodị na anyị bu nje virus na mberede?

Enweela ọtụtụ akụkọ nyocha ma ọ bụ akwụkwọ nyocha ndị e bipụtara n'akwụkwọ akụkọ mba ụwa, na-egosi na "Ganoderma lucidum", nke bara ụba na polysaccharides, triterpenes na protein immunomodulatory, kwesịrị inyere anyị aka ịlụso coronavirus ọhụrụ ọgụ.

Eprel 2020 - Akwụkwọ akụkọ nke Molecule:Ganoderma lucidumnwere ma ihe mgbochi nje na ihe na-achịkwa ihe mgbochi

N'April 2020, ndị ọkà mmụta sayensị si Mahadum Chiang Mai na Royal Academy of Sciences nke Thailand bipụtara akwụkwọ nlegharị anya na Molecules.

Dabere na nsonaazụ nyocha nke ama ama ugbu a, ha enyochala “oke ebuka” nke nwere ike igbochi SARS, MERS, COVID-19 na coronaviruses ndị ọzọ site na ọtụtụ ihe ndị fungal na ebumnuche nke “igbochi mmegharị nje” na “ịhazi nzaghachi mgbochi”.N'ihi ya, polysaccharides, triterpenoids, na protein immunomodulatory siGanoderma lucidumEdepụtara ha niile n'ime ha.

Ebe nje virus ga-adabere na sel ka ọ dị ndụ ma gbasaa, ihe a na-akpọ "mgbochi nje" bụ ihe niile gbasara "itinye aka na usoro mmegharị nje na cell", na-eme ka nje ahụ ghara ịmịpụta ọtụtụ nje site na cell. .

Banyere nje ndị ahụ ka na-achọ ebumnuche n'èzí cell - ma ọ bụ nje nke wakporo ahụ ma ọ bụ nje ọhụrụ nke a tọhapụrụ na cell - a ga-ewepụ nje ndị a na nzaghachi mkpali nke usoro ahụ ji alụso ọrịa ọgụ.Mgbe nje ahụ kpochapụrụ, ma enwere ike ịkwụsị mmeghachi omume mkpasu iwe ozugbo enwere ike iji zere imebi mkpụrụ ndụ nkịtị na-adaberekwa na nhazi nke usoro ahụ ji alụso ọrịa ọgụ.

Ya mere,Ganoderma lucidum, nke nwere ihe ndị na-egbochi mmegharị nje ma na-edozi usoro ahụ ji alụso ọrịa ọgụ, yiri ka ọ bụ usoro mmanya okike maka igbochi na ịgwọ nje virus, na-enye mkpuchi okpukpu abụọ nke kwesịrị ịtụ anya ibelata ihe egwu nke coronaviruses gụnyere coronavirus ọhụrụ.

June 2020- "Akwụkwọ akụkọ China nke Pharmacology na Toxicology": Mmetụta nkeGanodermalucidumna-ewusi ike dị mkpa ike na ikpochapụ ihe ndị na-akpata ọrịa na mmetụta antiviral ya

N'otu aka ahụ n'echiche ndị ọkà mmụta Thai, Prọfesọ Zhi-Bin Lin nke Mahadum Peking bipụtakwara akwụkwọ na Chinese Journal of Pharmacology and Toxicology na June 2020, na-atụle ohere nke igbochi na ọgwụgwọ COVID-19 site na.Ganoderma lucidumsite na ma echiche nke TCM na-ewusi ike dị mkpa ike na iwepụ ihe ndị na-akpata ọrịa na echiche nke ọgwụ ọdịda anyanwụ na mgbochi nje.

Febụwarị 2021-Mmemme nke National Academy of Sciences: Ganoderma polysaccharides nwere ike belata ọnụọgụ coronavirus ọhụrụ na ngụgụ anụmanụ.

Akụkọ nke ndị otu Taiwan Academia Sinica bipụtara na PNAS (Proceedings of the National Academy of Sciences) na February 2021 kwadoro na:

Otu n'ime ihe ndị na-arụsi ọrụ ike naGanoderma lucidum, "Ganoderma lucidum polysaccharides", nwere ike ịbụ antiviral ma in vitro na in vivo, na-enye ihe akaebe sayensị kpọmkwem naGanoderma lucidumna-enyere aka igbochi na ịgwọ ọrịa coronavirus ọhụrụ.

Nke mbụ, na nnwale in vitro, ndị nchọpụta ahụ buru ụzọ mepụta mkpụrụ ndụ Vero E6 naGanoderma lucidumMwepụta polysaccharide (koodu aha RF3) ọnụ, wee gbakwunye coronavirus akwụkwọ akụkọ iji hụ ọnụọgụ nje virus na nlanarị cell mgbe awa 48 gachara.

Dị ka anyị niile maara, akwụkwọ akụkọ coronavirus na-awakpo ahụ mmadụ site na onye na-anabata ACE2 na cell.Mkpụrụ ndụ Vero E6 sitere na anụ ahụ akụrụ nke anụ ọhịa na-acha akwụkwọ ndụ akwụkwọ ndụ Africa nwere ike igosipụta ọnụ ọgụgụ buru ibu nke ndị na-anabata ACE2, yabụ mgbe ha batara na coronavirus ọhụrụ, nje ahụ nwere ike ịbanye n'ime sel ngwa ngwa iji mepụtaghachi ma gbasaa.

Nsonaazụ gosiri naGanoderma lucidumMwepụta nke polysaccharide nwere ike ibelata ọnụọgụ nje virus na ọkara na ntinye dị ala nke 2μg / ml n'emeghị ka mkpụrụ ndụ nwụọ.

Ndị nyocha ahụ meziri nnwale anụmanụ: ha bu ụzọ bute hamsters akwụkwọ akụkọ coronavirus wee nyezie haGanoderma lucidumpolysaccharide na-ewepụta ọnụ na hamsters na dose kwa ụbọchị nke 200 mg / kg maka ụbọchị 3.

Achọpụtara na ọnụọgụ nje na ngụgụ nke hamsters bụ nanị ihe dị ka ọkara nke ndị na-adịghị agwọ ọrịa (mmiri a na-enye), na ịdị arọ nke hamsters nọgidere n'otu ọkwa ahụ dị ka tupu ọrịa ahụ na-enweghị mmụba ma ọ bụ ibelata.Nke a pụtara naGanoderma lucidumMwepụta polysaccharide nwere ike ọ bụghị naanị igbochi uto nke coronavirus ọhụrụ na hamsters mana ọ nwekwara oke nchekwa nchekwa nri.

N'ezie, ọ dịghị mfe naGanoderma lucidumpolysaccharides nwere ike ịpụta na nyocha a.N'ihi na nke a bụ n'iji ya tụnyere ọgwụ mmadụ ma ọ bụ anụmanụ 2,855 nke US Food and Drug Administration (FDA) kwadoro na ihe fọrọ nke nta ka ọ bụrụ mmiri 200 nke ọgwụ ahịhịa ndị China bụ ndị dị irè n'ịgwọ ọrịa nje.

N'ikpeazụ,Ganoderma lucidumpolysaccharides bụ naanị akụrụngwa ọgwụ nwere ike ịkpata mmetụta mgbochi n'ahụ n'ezie na-akpataghị ọnwụ cell ma ọ bụ mbelata ibu.

Ọzọkwa, polysaccharides bụ naanị otu n'ime ihe na-arụ ọrụGanoderma lucidum.Ọ bụrụ na agbakwunyere polysaccharides na triterpenoids na Ganoderma lucidum iji lụso nje a ọgụ, gịnị ga-eme?

Mee 2021 - "International Journal of Medicinal Fungi":Ganoderma lucidum's itule mmetụta na-enyere mgbake na-ezere oké ọrịa

Na Mee 2021, n'ihi ihe mgbaàmà nke oyi baa na mgbanwe vaskụla nke akwụkwọ akụkọ coronavirus kpatara, akwụkwọ nyochaghachi nke ebipụtara na "International Journal of Medicinal Mushrooms" nke ndị ọkà mmụta sitere na Ngalaba Biochemistry na Molecular Biology nke Mahadum Jahangirnagar na Bangladesh na Agricultural. Extension Division Mushroom Development Research Institute nke Ministry of Agriculture of Bangladesh nyochara ike nke ụdị fungi dị iche iche na-arụ ọrụ iji gwọọ ma gbochie ọrịa siri ike wee kwubie na.Ganoderma lucidumyiri ka ọ bụ ọgwụ kachasị mma maka mmadụ niile ịlụ ọgụ megide COVID-19 n'etiti ụdị ero dị iche iche.

N'ihi na ndị ọrịa nwere novel coronary oyi baa na-agbake na ntụziaka nke ahụike kama na-akawanye njọ na ntụziaka nke ọrịa siri ike, o yiri ka ọ bụ naanị.Ganoderma lucidum, nke bara ụba na ihe dị iche iche na-arụ ọrụ, na-akacha mma na-edozi nguzozi n'etiti ACE (Angiotensin Converting Enzyme) na ACE2 (Angiotensin Converting Enzyme 2) na nguzozi n'etiti ịkwalite nzaghachi mgbochi (mgbochi nje) na igbochi mkpasu iwe. nzaghachi (sel nchekwa).

Febụwarị 2020-Nri nri na nri ahụike China:Ganoderma lucidumnwere ike inye aka gbochie ma gwọọ ọrịa coronavirus ọhụrụ

"Ihe edemede sayensị nke abụọ a ma ama banyere enyemaka ziri ezi na mgbochi na ọgwụgwọ nke ọrịa coronavirus ọhụrụ n'ihe gbasara nri nri - ọrụ nke mgbakwunye nri" nke China Nutrition and Health Food Association bipụtara mara ọkwa ọha mmadụ ụdị nri iri na abụọ nke na-enyere aka igbochi. ma gwọọ coronavirus ọhụrụ, gụnyereGanoderma lucidum.

Akụkọ ahụ rụtụrụ aka n'ụzọ doro anya:Ganoderma lucidumnwere mmetụta na-akpali akpali nke na-alụso ọrịa ọgụ, nke nwere ike imetụta ikike ya ịlụso nje bacteria na nje virus ọgụ ozugbo.

Ọ dị ka agbụrụ dị n'etiti mmadụ na coronavirus agaghị akwụsị n'oge na-adịghị anya.Nje nje mutant nke na-agba ọsọ ọsọ adịghị ka ọ bụ Delta naanị ya.

Ọ bụrụ na ịchọrọ ịnọ n'ihu na-enweghị nje virus ejide gị, rie nke ukwuuGanoderma lucidumnke ahụ bụ “gbapụtara na sayensị”!Ganoderma lucidum, nke nwere ike ịchọta, nchekwa, ntụkwasị obi ma nwee polysaccharides na triterpenes, ekwesịghị ịhapụ gị.

[Ebe data]

1. Suwannarach N, et al.Ngwakọta bioactive eke sitere na fungi dị ka ndị Candidates maka Protease Inhibitors na Immunomodulators itinye akwụkwọ maka Coronaviruses.Molecules.2020, 25(8): 1800. doi:10.3390/molecules25081800.

2. Zhi-Bin Lin.Na-eme ka ike dị mkpa dị ike na ikpochapụ ihe ndị na-akpata ọrịa na mmetụta antiviral nke Ganoderma lucidum.Akwụkwọ akụkọ China nke Pharmacology na Toxicology.2020;34 (6): 401-407.

3. Jia-Tsrong Jan, et al.Nchọpụta nke ọgwụ dị adị na ọgwụ herbal dị ka ndị na-egbochi ọrịa SARS-CoV-2.Proc Natl Acad Sci US A. 2021 Feb 2;118(5):e2021579118.doi: 10.1073/pnas.2021579118.

4. Mohammad Azizur Rahman, et al.Nhazi usoro mgbochi na ọgwụgwọ dabere ero na COVID-19: Nyochaa.Int J Med ero.2021;23 (5): 1-11 .doi: 10.1615/IntJMedMushrooms.2021038285.

N'ikpeazụ 

Banyere onye odee/ Oriakụ Wu Tingyao

Wu Tingyao na-akọ akụkọ gbasara Ganoderma lucidum ozi kemgbe 1999. Ọ bụ ya bụ onye dere akwụkwọ akụkọ.Ọgwụgwọ na Ganoderma(nke e bipụtara na The People's Medical Publishing House na Eprel 2017).

★ A na-ebipụta akụkọ a n'okpuru ikike nke onye edemede, na onye nwe ya bụ GANOHERB ★ Ọrụ ndị dị n'elu enweghị ike ịmegharị, wepụ ma ọ bụ jiri ya mee ihe n'ụzọ ndị ọzọ na-enweghị ikike nke GanoHerb ★ Ọ bụrụ na enyere ikike iji ọrụ ndị ahụ, ha kwesiri iji ya mee ihe n'ime oke ikike ma gosi isi mmalite: GanoHerb ★ Maka mmebi ọ bụla nke nkwupụta a dị n'elu, GanoHerb ga-agbaso ọrụ iwu metụtara ya ★ Wu Tingyao dere ederede mbụ nke isiokwu a n'asụsụ Chinese wee sụgharịa ya n'asụsụ Bekee site n'aka Alfred Liu.Ọ bụrụ na enwere nghọtahie n'etiti ntụgharị asụsụ (Bekee) na nke izizi (Chinese), Chinese izizi ga-emeri.Ọ bụrụ na ndị na-agụ akwụkwọ nwere ajụjụ ọ bụla, biko kpọtụrụ onye edemede mbụ bụ Oriakụ Wu Tingyao.

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