(Daim duab credit: Xib Fwb John Nicholls, Clinical Professor of Department of Pathology, HKUMed; and Professor Malik Peiris, Tam Wah-Ching Professor in Medical Science and Chair Professor of Virology, School of Public Health, HKUMed; and Electron Microscope Unit, HKU. )

Ua ntej txheeb xyuas "txawm tias peb yuav tsum txhawj xeeb txog Omicron variant lossis tsis", cia peb xub paub txog SARS-CoV-2 Omicron variant, uas tsuas yog tshwm sim hauv South Africa thaum 9 Kaum Ib Hlis 2021, cheb lub ntiaj teb los ntawm qhov kawg ntawm qhov tom ntej. hli thiab tau ua cov lus zoo li kev sib kis kab mob, koob thib peb thiab txhawb rau hauv kev tshawb fawb kub.

Cov kab mob sib kis tau zoo heev ua rau nws nyuaj rau peb tiv thaiv kab mob.

Cov duab hluav taws xob microscopic thaum pib ntawm tsab xov xwm yog lub ntiaj teb thawj daim duab "Omicron" tso tawm los ntawm Li Ka Shing Kws Kho Mob, University of Hong Kong (HKUMed) thaum Lub Kaum Ob Hlis 8, 2021:

Qhov saum npoo ntawm tus kab mob no muaj lub ntsej muag zoo li lub ntsej muag, uas yog cov protein ntau (S protein) siv los ntawm tus kab mob los txeeb lub cell.

Tus kab mob no tso siab rau cov kab mob loj no los khi rau cov receptors ntawm lub xov tooj ntawm tes, ua rau lub cell endocytosis mechanism qhib lub qhov rooj rau tus yeeb ncuab txaus ntshai thiab tom qab ntawd nkag mus rau lub hlwb los pab lawv rov ua cov kab mob tshiab kom lawv kis tau ntau lub hlwb.

Yog li ntawd, cov kab mob sib kis tsis yog tsuas yog tus yuam sij rau tus kab mob nkag mus rau cov hlwb tab sis kuj yog lub hom phiaj rau cov tshuaj tiv thaiv los qhia lub cev tiv thaiv kab mob kom "yeej" txheeb xyuas thiab ntes tus kab mob.Qhov ntau dua ntawm lawv qhov kev hloov pauv, qhov yooj yim dua yog rau cov tshuaj tiv thaiv kab mob tiv thaiv kom nco lawv.

Los ntawm cov duab hauv qab no piv cov qauv peb sab ntawm "Delta" thiab "Omicron" spike proteins luam tawm los ntawm lub tsev kho mob muaj koob npe Bambino Gesu hauv Rome thaum Lub Kaum Ib Hlis 27, 2021, koj tuaj yeem nkag siab tias yog vim li cas Omicron kis tau ntau dua li Delta.

(Source/WHO official website)

Cov haujlwm uas cim los ntawm cov xim yog thaj chaw hloov pauv uas txawv ntawm tus kab mob thawj zaug.Raws li kev txheeb xyuas, muaj tsawg kawg yog 32 qhov kev hloov pauv tseem ceeb hauv cov protein ntau ntawm "Omicron", deb tshaj "Delta", thiab thaj chaw hloov pauv loj heev (liab) kuj tseem muaj nyob hauv cov haujlwm uas cuam tshuam nrog tib neeg lub hlwb.

Cov kev hloov pauv no ua rau nws yooj yim dua rau "Omicron" txhawm rau txhawm rau tib neeg lub hlwb kom rov tsim dua tshiab, kis mus rau tib neeg thiab tshem tawm cov tshuaj tiv thaiv kab mob uas twb muaj lawm, ua rau muaj kev sib kis lossis rov ua dua tshiab.

"Omicron" yooj yim kis mus rau bronchus tab sis tsis tshua nkag mus rau hauv lub ntsws.

Raws li cov kev tshawb fawb tau luam tawm los ntawm HKUMed ntawm nws lub vev xaib raug cai thaum Lub Kaum Ob Hlis 15, Omicron variant replicates nyob ib ncig ntawm 70 lub sij hawm sai dua Delta thiab thawj Covid-19 hom kab mob hauv tib neeg lub ntsws tab sis tsis zoo hauv tib neeg lub ntsws.

(Daim duab Source/HKUMed official website)

Qhov no yuav piav qhia tias yog vim li cas "Omicron" kis tau sai sai thaum cov tsos mob pib ntawm tus kab mob (nqhis caj pas, qhov ntswg qhov ntswg) tuaj yeem ua yuam kev rau tus mob khaub thuas, tab sis qhov mob hnyav ntawm tus kab mob kuj tsawg.

Tab sis tsis txhob maj maj vim "Omicron" tsis tshua muaj peev xwm ua rau mob hnyav.Leej twg paub tias qhov kawg tshwm sim tos peb?

Dab tsi ntxiv, muaj "Delta" thiab "Influenza" tseem ntsia peb tib lub sijhawm!Txoj hauv kev zoo tshaj los zam lawv yog sim tswj peb txoj kev tiv thaiv ntawm qib siab txhua hnub.

Yog li peb tsis tas yuav txhawj xeeb ntau txog "Omicron" tab sis peb yuav tsum tau ceev faj kom ceev faj.

Nws yuav zoo li cas yog tias ib lub xovtooj tau kis nrog Omicron variant?

Ua tib zoo saib cov duab hauv qab no ntawm electron microscopic muab los ntawm HKUMed.

(Duab Credit/HKUMed & Electron Microscope Unit, HKU)

Qhov no yog lub tshuab hluav taws xob ntawm Vero (lub raum liab) ntawm tes 24 teev tom qab kis kab mob nrog Omicron variant ntawm SARS-CoV-2.Koj tuaj yeem pom tias ntau cov kab mob tau rov ua dua hauv cov hlwv ntawm tes, thiab cov kab mob uas tau rov ua dua tau raug tso tawm mus rau ntawm lub xov tooj ntawm tes npaj ua lawv txoj haujlwm.

Qhov no tsuas yog tus kab mob tshiab tsim los ntawm tus kab mob siv "ib lub xov tooj".Nws yog ceev heev!Hmoov zoo, nws tsuas yog kev sim hauv vitro cell.Yog tias nws tshwm sim hauv vivo, peb tsis paub tias muaj pes tsawg lub hlwb yuav raug kev txom nyem, thiab tus neeg mob lub sijhawm no feem ntau asymptomatic;thaum ib tug xav tias yuam kev thiab xav tiv thaiv, nws lig dhau lawm!

Tom qab kis kab mob, qee tus kab mob yuav nyob hauv lub cell thaum qee tus yuav nyob sab nraud ntawm tes.Lub cev tiv thaiv kab mob yuav cuam tshuam nrog cov kab mob sib txawv.

Antibodies induced los ntawm txhaj tshuaj tiv thaiv tsuas yog ntes tau (neutralize) tus kab mob sab nraum lub cell.Yog tias tus kab mob tuaj yeem cuam tshuam sai li sai tau thaum nws nkag mus rau hauv lub xov tooj ntawm tes, tej yam yooj yim kuj yooj yim;Yog hais tias tus kab mob kis mus rau hauv lub cell, lub cev tiv thaiv kab mob yuav tsum tau secrete interferon los thaiv cov kab mob replication nyob rau hauv lub hlwb thiab txo tus nqi thiab ceev ntawm tus kab mob proliferation thiab tseem xav tau "killer T cells" los yog "natural killer cells" los tua cov kab mob.

Ob tus kab mob ntes tau los ntawm cov tshuaj tiv thaiv kab mob thiab tua cov kab mob yuav tsum tau macrophages los khaws cov khoom.Ua ntej no, macrophages thiab dendritic hlwb kuj tseem yuav pab xa cov teeb liab mus rau "tus pab T cells", cov thawj coj loj ntawm lub cev tiv thaiv kab mob, uas tom qab ntawd muab cov lus txiav txim kom raug los tsim cytotoxic T hlwb thiab neutralizing cov tshuaj tiv thaiv.

Kev txhaj tshuaj tiv thaiv tuaj yeem ua rau cov tshuaj tiv thaiv kab mob, thiab cov tshuaj tiv thaiv kab mob tuaj yeem cuam tshuam tus kab mob rov ua dua tshiab hauv cov hlwb thiab ua rau qeeb kis tus kab mob.Txawm li cas los xij, txhawm rau txhawm rau tshem tawm tus kab mob tiag tiag, nws xav tau txhua yam ntawm lub cev tiv thaiv kab mob kom tau txais kev txhawb nqa thiab txhawb nqa.

Yog li, tom qab txhaj tshuaj tiv thaiv, yuav ua li cas txhawm rau txhim kho lub cev tiv thaiv kab mob, ntxiv dag zog rau lub cev tiv thaiv kab mob, txhim kho kev tiv thaiv kab mob, txhawb kev tiv thaiv kab mob, thiab tsis txhob mob ntau dhau?

Txij li kev tshawb fawb hauv xyoo 1990,Ganoderma lucidumtau raug pov thawj los ua kom lub cev loj hlob ntawm dendritic hlwb, tswj kev sib txawv ntawm T hlwb, txhawb kev tsim cov tshuaj tiv thaiv los ntawm B hlwb, txhawb kev sib txawv ntawm monocytes-macrophages, thiab txhim kho cov kev ua ntawm ntuj killer hlwb, pab nrog kev loj hlob ntawm ntau yam. Lub cev tiv thaiv kab mob thiab kev tso tawm ntawm ntau yam cytokines, thiab muaj kev tswj hwm zoo ntawm lub cev tiv thaiv kab mob.Cov teebmeem no tau muab sau tseg rau hauv daim duab hauv qab no.

Hauv kev rov qab los, peb yuav piav qhia rau koj ntxiv rau qhov tob "vim li casGanoderma lucidumtuaj yeem pab peb ntxiv dag zog rau kev tiv thaiv peb xav tau los tua cov kab mob "los ntawm ntau cov ntaub ntawv uas tau luam tawm hauv cov ntawv xov xwm thoob ntiaj teb.Ua ntej ntawd, peb vam tias koj tau pib nojGanoderma lucidumvim kev tiv thaiv txhua hnub tseem ceeb heev.Tsuas yog los ntawm kev tswj hwm lub cev tiv thaiv kab mob zoo txhua hnub tuaj yeem ua kom peb muaj kev nyab xeeb txhua hnub.

END

★ Kab lus no tau luam tawm raws li kev tso cai tshwj xeeb ntawm tus sau, thiab cov tswv cuab yog GANOHERB.

★ Cov haujlwm saum toj no tsis tuaj yeem muab luam tawm, txiav tawm lossis siv lwm txoj hauv kev yam tsis muaj kev tso cai ntawm GanoHerb.

★ Yog tias cov haujlwm tau tso cai siv, lawv yuav tsum tau siv nyob rau hauv qhov kev tso cai thiab qhia qhov chaw: GanoHerb.

★ Rau ib qho kev ua txhaum cai ntawm cov lus hais saum toj no, GanoHerb yuav ua raws li cov luag haujlwm raug cai.

★ Cov ntawv qub ntawm kab lus no tau sau ua lus Suav los ntawm Wu Tingyao thiab txhais ua lus Askiv los ntawm Alfred Liu.Yog tias muaj qhov tsis sib xws ntawm kev txhais lus (English) thiab tus thawj (Suav), tus thawj Suav yuav yeej.Yog tias cov nyeem muaj lus nug, thov hu rau tus thawj kws sau ntawv, Ms. Wu Tingyao.

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