Nhau dzekusiya basa kwegurukota reJapan Shinzo Abe dzakaita kuti pasi rose richerechedze ulcerative colitis.Chikonzero chikuru chechirwere ichi chiri mukukundikana kwekugadzirisa hurongwa hwekudzivirira zvirwere, zvichikonzera kurwiswa kakawanda kwekuputika.

Ganoderma lucidum, iyo yakagara ichipa pfungwa ye "kuwedzera kudzivirirwa", chaizvoizvo inyanzvi pa "kugadzirisa kuzvimba".

Ulcerative colitis chete idambudziko guru.Kana iwe uchida nyama yakabikwa yakanyanya kupisa kana nyama tsvuku mukudya kwako, zvinonyanya kukurudzira kuzvimba kwematumbo uye cancer yemudumbu.

Zvisinei, kana ganoderma triterpene inogona kushandiswa kuchengetedza matumbo, inogona kukwanisa kugadzirisa dambudziko rakawanda.Nekuti maererano nekuyedza kwemhuka kwakabudiswa naProfessor Daniel Sliva weIndiana University Chikoro cheMishonga mu "PLOS ONE" muna 2012:

Oral management yeGLT, triterpene inobvisa yeGanoderma lucidum fruiting body, inogona kuderedza chiyero chekuzvimba kwemukati uye kukuvadzwa, kuderedza kuwanda kwepolyp uye maronda ematishu, uye inhibisa gomarara uye kukura kwebundu kana zvinhu zviviri zviri pamusoro apa zvine njodzi.

Uyezve, kusati kwadzivirirwa (kutora 300 mg / kg katatu pavhiki) kunoshanda kupfuura kutungamirira Ganoderma triterpene (kutora 500 mg / kg katatu pavhiki) apo njodzi inooneka, uye chiyero chinodiwa chakadererawo (Ona. tafura iri pazasi).

Chengetedza masero emukati uye kubvisa kuzvimba ndiyo kiyi
 
Mukureba kwenguva refu kwekudya carcinogens uye ulcerative colitis, neiReishi mushroomtriterpene GLT inogona kudzivirira matumbu? Maererano nehumbowo hwakaongororwa muchidzidzo ichi, zvikonzero zvinogona kukamurwa kuita zvinhu zvitatu:
1. Deredza huturu hwemakenza: gadzirisa enzyme (cytochrome P450) iyo inogadzirisa heterocyclic amine PhIP mumuviri, uye kudzivirira PhIP kuti irege kushandiswa ne enzyme kuita chinhu chine carcinogenic basa.
2. Chengetedza masero emukati: inhibisa kushandiswa kweprotein molecules inobatanidzwa mukuputika uye kuwedzera kwesero mumasero emukati (Mufananidzo 1) kuitira kuti zvirege kushandiswa nyore nyore ne enteritis stimuli uye intestinal carcinogens.
3. Kugadzirisa maitiro ekudzivirira zvirwere: kuderedza nhamba ye macrophages inopinda mucolon tissue (Mufananidzo 2), kuitira kuti mhinduro yekuputika irege kuramba ichiwedzera nekuda kwekunyanya kubatanidzwa kwema macrophages, nokudaro kuderedza kuputika uye kuderedza mukana wekenza yesero.

Mufananidzo 1: Ganoderma triterpenes inhibit abnormal cell proliferation

Mufananidzo 2: Ganoderma triterpenes inhibisa kuzvimba kupindura kwema macrophages

Inokurudzirwa dosage yemuviri wemunhu

Iyo GLT inoshandiswa muchidzidzo ichi ndeye triterpene musanganiswa unowanikwa nekubvisa michero miviri yeGanoderma lucidum neimwe nzira.Zvikamu zvaro zvikuru ganoderic acid A (3.8 mg / g), ganoderic acid H (1.74 mg / g) uye ganoderic acid F (0.95 mg / g).
 
Vatsvakurudzi vakashandura dhizimusi yepamusoro-soro mukuedza kwembeva kuita dosi remunhu mukuru ane huremu hwe60 kusvika 80 kilogram.90-120 magiramu eGLT pavhiki (avhareji ye12.9 kusvika 17.1 magiramu eGLT pazuva) angave nemhedzisiro yakafanana mukuedza kwemhuka.
 
Sezvo huremu hwemhuka dzekuyedza dzinodya GLT huchiri kuwedzera zvakajairika, uye hapana chiropa chisina kujairika uye chepfu yeitsvo, ropa lipid metabolism uye glucose yeropa metabolism.Naizvozvo, kune vanhu vanoda nyama tsvuku asi zvakare vane ulcerative colitis, kuwedzera Ganoderma lucidum triterpenes kudzivirira nekurapa colorectal cancer inoita seyakakodzera kutariswa.
 
Lingzhiinogadzirisa hutachiona uye inokodzerawo kuzvimba zvisina kujairika
 
Nekuda kwenhau dzekusiya basa kwaAbe, tsvakiridzo yakapfuura paGanoderma lucidum yakaonekwa, ndokuzongoona kuti Ganoderma lucidum polysaccharides uye triterpenes ine mhedzisiro paulcerative colitis.
 
Muchokwadi, Ganoderma lucidum inogona zvakare kudzoreredza Chirwere cheCrohn, imwe mhando yehutachiona hwehutachiona hunokonzerwa ne autoimmunity, uye huturu hudiki hunokonzerwa nemarwadzo ekurwadziwa (ona References 2 kusvika 4 kuti uwane mamwe mashoko).
 
Mhedzisiro iyi inowedzera kuratidza kuti Ganoderma lucidum inokwanisa kudzora kuzvimba uye kuwedzera kusadzivirirwa.
 
Yakasiyana Ganoderma lucidum ingredients ine mabasa akasiyana.Kana Ganoderma lucidum polysaccharides uye Ganoderma lucidum triterpenes inogona kudyiwa panguva imwe chete, mhedzisiro ichava nani.
 
Nekudaro, zvisinei kuti ndechipi chinongedzo cheGanoderma lucidum chinodyiwa, kunyangwe uchichidya wega kana kuchizivisa kumhuri yako neshamwari, ndapota iva nechokwadi chekusarudza Ganoderma lucidum zvigadzirwa zvehuhu hunoenderana, nekuti chete kwakasimba kwekambani kudzora zviyero kunogona kuve nechokwadi chekuchengetedza uye efficacy yezvigadzirwa kubva kune strain kusvika pakugadziriswa.Kudzora kwemhando yepamusoro kunogona kuita zvigadzirwa zvinoita kuti muviri wemunhu urambe uine hutano.
 
References
1. Sliva D, nevamwe.Mushroom Ganoderma lucidum inodzivirira colitis-associated carcinogenesis mumakonzo.PLoS Imwe.2012;7(10):e47873.
2. Liu C, nevamwe.Anti-inflammatory Effects yeGanoderma lucidumTriterpenoid muHuman Crohn's Disease Inobatanidza neDownregulation yeNF-κB Signaling.Inflamm Bowel Dis.2015 Aug;21(8):1918-25.
3. Hanaoka R, nevamwe.Mvura inonyungudika kubva kuGanoderma lucidum (Reishi) mycelia (Yakasarudzwa seMAK) inovandudza murine colitis inokonzerwa ne trinitrobenzenesulphonicacid.Scand J Immunol.2011 Nov;74(5):454-62.

4. Nagai K, nevamwe.Polysaccharides inotorwa kubva kuGanoderma lucidum fungus mycelia ameliorate indomethacin-induced intestinal kukuvara kwemukati kuburikidza nekuiswa kweGM-CSF kubva macrophages.Cell Immunol.2017 Oct;320:20-28.

Nezve munyori/ Ms. Wu Tingyao
Wu Tingyao anga achirondedzera nezvekutanga-ruoko Ganoderma lucidum ruzivo kubvira 1999. Ndiye munyori we "Ganoderma lucidum: Ingenious Beyond Description" (yakabudiswa muThe People's Medical Publishing House muna April 2017).

★ Chinyorwa ichi chakaburitswa pasi pemvumo yakasarudzika yemunyori, uye muridzi ndeweGANOHERB ★ Mabasa ari pamusoro haagone kudhindwa, kutorwa kana kushandiswa nedzimwe nzira pasina mvumo yeGanoHerb ★ Kana mabasa acho akatenderwa kushandiswa, iwo inofanira kushandiswa mukati mechikamu chemvumo uye kuratidza kwainobva: GanoHerb ★ Kutyora chirevo chiri pamusoro, GanoHerb ichatevera mabasa ayo ane chekuita nemutemo.

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