Akụkọ banyere arụkwaghịm nke minista Japan bụ Shinzo Abe mere ka ụwa mara ọrịa ulcerative colitis.Ihe na-akpata ọrịa a bụ ọdịda nke usoro nchịkwa nke usoro ahụ ji alụso ọrịa ọgụ, na-ebute mbufụt ugboro ugboro.

Ganoderma lucidum, nke na-enye mgbe niile echiche nke "ịkwalite mgbochi", bụ n'ezie nna ukwu na "ịchịkwa mbufụt".

Ulcerative colitis naanị bụ nnukwu nsogbu.Ọ bụrụ na ị na-ahọrọ anụ esiri esi ọkụ ma ọ bụ anụ uhie na nri gị, ọ ga-abụ na ọ ga-akwalite mbufụt nke eriri afọ na ọrịa cancer colorectal.

Otú ọ dị, ọ bụrụ na a pụrụ iji ganoderma triterpene mee ihe iji nọgide na-enwe eriri afọ, ọ nwere ike dozie ọtụtụ nsogbu ahụ.N'ihi na dị ka nnwale anụmanụ nke Prọfesọ Daniel Sliva nke Indiana University School of Medicine bipụtara na "PLOS ONE" na 2012:

Nlekọta ọnụ nke GLT, ihe nchịkọta triterpene nke mkpụrụ osisi Ganoderma lucidum, nwere ike ibelata ogo nrịanrịa na mmebi nke eriri afọ, belata mgbasa nke polyp na ọnya anụ ahụ, ma gbochie ọrịa cancer na tumor mgbe ihe abụọ dị n'elu dị n'elu na-ejikọta ọnụ.

Ọzọkwa, tupu nchekwa (na-ewere 300 mg / kg ugboro atọ n'izu) dị irè karịa inye Ganoderma triterpene (na-ewere 500 mg / kg ugboro atọ n'izu) mgbe ihe ize ndụ pụtara, na dose achọrọ dịkwa ala (Lee. Tebụl dị n'okpuru).

Chebe mkpụrụ ndụ eriri afọ ma belata mbufụt bụ isi ihe
 
Na mmetụta ogologo oge nke carcinogens nri na ulcerative colitis, gịnị kpatara yaReishi erotriterpene GLT nwere ike inye nchebe maka eriri afọ? Dị ka ihe akaebe nyochara na ọmụmụ a, enwere ike kewaa ihe kpatara ya n'ụzọ atọ:
1. Belata nsi nke carcinogens: mezie enzyme (cytochrome P450) nke na-emepụta heterocyclic amine PhIP n'ime ahụ, ma gbochie PhIP site na enzyme na-arụ ọrụ n'ime ihe nwere ọrụ carcinogenic.
2. Chebe mkpụrụ ndụ intestinal: gbochie ịgbalite ụmụ irighiri protein na-etinye aka na mbufụt na mmụba cell n'ime sel eriri afọ (Njirimara 1) ka ọ ghara ime ka ọ dị mfe site na mkpali enteritis na carcinogens intestinal.
3. Na-ahazi nzaghachi mgbochi ahụ: belata ọnụ ọgụgụ nke macrophages na-abanye n'ime anụ ahụ colon (Nyocha 2), nke mere na nzaghachi mkpali agaghị anọgide na-amụba n'ihi oke oke nke macrophages, si otú ahụ na-ebelata mbufụt na ibelata ohere nke cell cancer.

Ọnụọgụ 1: Ganoderma triterpenes na-egbochi mgbasa mkpụrụ ndụ na-adịghị mma

Ọgụgụ 2: Ganoderma triterpenes na-egbochi nzaghachi mbufụt nke macrophages

Usoro ọgwụgwọ akwadoro maka ahụ mmadụ

GLT ejiri mee ihe n'ọmụmụ ihe a bụ ngwakọta triterpene nke enwetara site n'iwepụta ozu nke Ganoderma lucidum na-amị mkpụrụ n'ụzọ a kapịrị ọnụ.Ihe ndị mejupụtara ya bụ ganoderic acid A (3.8 mg/g), ganoderic acid H (1.74 mg/g) na ganoderic acid F (0.95 mg/g).
 
Ndị nyocha ahụ tụgharịrị ọgwụ kachasị dị irè na nnwale òké ka ọ bụrụ dose maka okenye nwere kilogram 60 ruo 80.90-120 grams nke GLT kwa izu (nkezi nke 12.9 ruo 17.1 grams nke GLT kwa ụbọchị) ga-enwe mmetụta yiri nke ahụ na nyocha anụmanụ.
 
Ebe ọ bụ na ịdị arọ nke anụmanụ nnwale na-eri GLT ka na-abawanye nke ọma, ọ nweghịkwa imeju na akụrụ na-adịghị mma, metabolism lipid ọbara na metabolism glucose ọbara.Ya mere, maka ndị na-amasị anụ uhie ma na-enwekwa ulcerative colitis, na-agbakwunye Ganoderma lucidum triterpenes iji gbochie na ịgwọ ọrịa cancer colorectal yiri ka e kwesịrị ịtụle.
 
Lingzhina-achịkwa ihe mgbochi ma dịkwa mma maka mbufụt na-adịghị mma
 
N'ihi akụkọ banyere arụkwaghịm nke Abe, nchọpụta gara aga na Ganoderma lucidum tụgharịrị, naanị ịchọta na Ganoderma lucidum polysaccharides na triterpenes nwere mmetụta na ulcerative colitis.
 
N'ezie, Ganoderma lucidum nwekwara ike inyefe Ọrịa Crohn, ụdị ọzọ nke ọrịa bowel na-egbuke egbuke nke autoimmunity kpatara, na obere eriri afọ na-egbu mgbu kpatara (lee ntụaka 2 ruo 4 maka nkọwa).
 
Nsonaazụ ndị a na-egosikwa na Ganoderma lucidum nwere ikike ịchịkwa mbufụt na ịkwalite mgbochi.
 
Ihe dị iche iche Ganoderma lucidum nwere ọrụ dị iche iche.Ọ bụrụ na Ganoderma lucidum polysaccharides na Ganoderma lucidum triterpenes nwere ike iri n'otu oge, mmetụta ahụ ga-aka mma.
 
Otú ọ dị, n'agbanyeghị ihe mgwa nke Ganoderma lucidum a na-eri, ma ị na-eri ya n'onwe gị ma ọ bụ na-ewebata ya na ezinụlọ gị na ndị enyi gị, biko jide n'aka na ị ga-ahọrọ ngwaahịa Ganoderma lucidum nke na-agbanwe agbanwe, n'ihi na ọ bụ naanị njikwa ụkpụrụ ụlọ ọrụ siri ike nwere ike hụ na nchekwa na nchekwa. ịdị irè nke ngwaahịa site na nsogbu ruo nhazi.Ịchịkwa ọkwa dị mma nwere ike ime ka ngwaahịa ndị na-eme ka ahụ mmadụ dịkwuo mma.
 
Ntụaka
1. Sliva D, et al.Mushroom Ganoderma lucidum na-egbochi ọrịa carcinogenesis metụtara colitis na ụmụ oke.PLoS One.2012;7 (10): e47873 .
2. Liu C, et al.Mmetụta mgbochi mkpali nke Ganoderma lucidumTriterpenoid na Ọrịa Crohn nke mmadụ jikọtara ya na Downregulation nke NF-κB Signaling.Ọkpụkpụ eriri afọ.2015 Ọgọst; 21 (8): 1918-25 .
3. Hanaoka R, et al.Na mmiri-soluble wepụ si cultured ọkara nke Ganoderma lucidum (Reishi) mycelia (Edepụtara dị ka MAK) emeliorates murine colitis butere trinitrobenzenesulphonicacid.Scand J Immunol.2011 Nov; 74 (5): 454-62 .

4. Nagai K, et al.Polysaccharides sitere na Ganoderma lucidum fungus mycelia ameliorate indomethacin na-ebute mmerụ ahụ nke obere eriri afọ site na ntinye nke GM-CSF site na macrophages.Immunol cell.2017 Ọkt; 320:20-28 .

Banyere onye odee/ Oriakụ Wu Tingyao
Wu Tingyao na-akọ banyere ozi Ganoderma lucidum nke mbụ kemgbe 1999. Ọ bụ onye edemede nke "Ganoderma lucidum: Ingenious Beyond Description" (nke e bipụtara na Ụlọ Nbipụta Ahụike Ndị Mmadụ na April 2017).

★ A na-ebipụta akụkọ a n'okpuru ikike nke onye edemede, na onye nwe ya bụ GANOHERB ★ Ọrụ ndị dị n'elu enweghị ike ịmegharị, wepụ ma ọ bụ jiri ya mee ihe n'ụzọ ndị ọzọ na-enweghị ikike nke GanoHerb ★ Ọ bụrụ na enyere ikike iji ọrụ ndị ahụ, ha ekwesịrị iji ya mee ihe n'ime oke ikike wee gosi isi mmalite: GanoHerb ★ Mmebi okwu a dị n'elu, GanoHerb ga-agbaso ọrụ iwu metụtara ya.

Nyefee na Omenala Ahụike Millennia
Nye aka na ịdịmma maka mmadụ niile