Amakuru y’iyegura rya minisitiri w’Ubuyapani Shinzo Abe yatumye isi imenyekanisha colitis ulcerative colitis.Intandaro yiyi ndwara iri mu kunanirwa kugenzura imikorere y’umubiri, bigatera ibitero inshuro nyinshi.

Ganoderma lucidum, buri gihe cyatanze igitekerezo cyo "kongera ubudahangarwa", mubyukuri ni umuhanga "kugenzura ibicanwa".

Indwara ya kolite yonyine ni ikibazo gikomeye.Niba ukunda inyama zitetse cyane cyangwa inyama zitukura mumirire yawe, birashoboka cyane gutera uburibwe bwo munda na kanseri yibara.

Ariko, niba ganoderma triterpene ishobora gukoreshwa mukubungabunga amara, irashobora gukemura ibibazo byinshi.Kuberako ukurikije ubushakashatsi bwinyamaswa bwashyizwe ahagaragara na Porofeseri Daniel Sliva wo mu Ishuri Rikuru ry’Ubuvuzi rya Indiana muri “PLOS ONE” muri 2012:

Ubuyobozi bwo mu kanwa bwa GLT, ikomoka kuri triterpene yumubiri wera imbuto ya Ganoderma lucidum, irashobora kugabanya urugero rwo gutwika amara no kwangirika, kugabanya ikwirakwizwa rya polyp hamwe nudukoko twangiza, kandi bikabuza kanseri no gukura kwikibyimba mugihe ibintu bibiri byavuzwe haruguru bibana.

Byongeye kandi, kubanza kurinda (gufata 300 mg / kg inshuro eshatu mu cyumweru) bigira akamaro kuruta gutanga Ganoderma triterpene (gufata 500 mg / kg inshuro eshatu mu cyumweru) mugihe hagaragaye impanuka, kandi ikinini gisabwa nacyo kiri hasi ((Reba imbonerahamwe ikurikira).

Kurinda selile zo munda no kugabanya uburibwe nurufunguzo
 
Mu ngaruka ndende ziterwa na kanseri y'ibiryo na colitis ulcerative, kukiReishi mushroomtriterpene GLT irashobora kurinda amara？ Dukurikije ibimenyetso byasesenguwe muri ubu bushakashatsi, impamvu zishobora kugabanywamo ibice bitatu:
1. Kugabanya uburozi bwa kanseri: kugenga enzyme (cytochrome P450) ihindura metabolike ya amine PhIP mu mubiri, kandi ikabuza PhIP gukora na enzyme mubintu bifite ibikorwa bya kanseri.
2. Kurinda ingirangingo zo munda: kubuza gukora molekile za poroteyine zigira uruhare mu gutwika no gukwirakwira mu ngirabuzimafatizo zo mu mara (Ishusho 1) kugira ngo zidakorwa mu buryo bworoshye na enteritis itera na kanseri yo mu nda.
3. Tunganya igisubizo cyubudahangarwa: gabanya umubare wa macrophage winjira mumyanya ndangagitsina (Igicapo 2), kugirango igisubizo cyo gutwika kitazakomeza kwaguka kubera uruhare runini rwa macrophage, bityo bikagabanya gucana no kugabanya amahirwe yo guhagarika selile.

Igishushanyo 1: Ganoderma triterpène ibuza ikwirakwizwa ryimikorere idasanzwe

Igishushanyo 2: Ganoderma triterpène ibuza igisubizo cya macrophage

Gusabwa dosiye kumubiri wumuntu

GLT ikoreshwa muri ubu bushakashatsi ni imvange ya triterpene yabonetse mu gukuramo imibiri yera ya Ganoderma lucidum muburyo bwihariye.Ibigize byingenzi ni aside ganoderic A (3,8 mg / g), aside ganoderic H (1,74 mg / g) na aside ganoderic F (0,95 mg / g).
 
Abashakashatsi bahinduye igipimo cyiza cyane mubushakashatsi bwimbeba mo igipimo cyumuntu mukuru ufite ibiro 60 kugeza kuri 80.Garama 90-120 za GLT buri cyumweru (impuzandengo ya garama 12.9 kugeza 17.1 za GLT kumunsi) byagira ingaruka nkizo mubushakashatsi bwinyamaswa.
 
Kubera ko uburemere bwinyamaswa zigeragezwa zikoresha GLT zikomeje kwiyongera mubisanzwe, kandi nta mwijima udasanzwe nuburozi bwimpyiko, metabolisme yamaraso hamwe na glucose metabolism.Kubwibyo, kubantu bakunda inyama zitukura ariko bakanagira colitis ibisebe, kuzuza Ganoderma lucidum triterpène kugirango birinde no kuvura kanseri yibara bisa nkibikwiye kwitabwaho.
 
Lingzhiigenga ubudahangarwa kandi ikwiriye no gutwikwa bidasanzwe
 
Kubera amakuru y’uko Abe yeguye, ubushakashatsi bwashize kuri Ganoderma lucidum bwaragaragaye, gusa ugasanga Ganoderma lucidum polysaccharide na triterpène bigira ingaruka kuri kolite y ibisebe.
 
Mubyukuri, Ganoderma lucidum irashobora kandi kugabanya indwara ya Crohn, ubundi bwoko bwindwara zifata amara ziterwa na autoimmunite, hamwe no gutwika amara mato biterwa n'imiti igabanya ububabare (reba Reba 2 kugeza 4 kugirango ubone ibisobanuro).
 
Ibisubizo birerekana kandi ko Ganoderma lucidum ifite ubushobozi bwo kugenzura umuriro no kongera ubudahangarwa.
 
Ibintu bitandukanye bya Ganoderma lucidum bifite imirimo itandukanye.Niba Ganoderma lucidum polysaccharide na Ganoderma lucidum triterpene ishobora kuribwa icyarimwe, ingaruka zizaba nziza.
 
Nubwo bimeze bityo ariko, ntakibazo kirimo Ganoderma lucidum ikoreshwa, waba urya wenyine cyangwa ukayimenyekanisha mumuryango wawe ninshuti, nyamuneka wemeze guhitamo ibicuruzwa bya Ganoderma lucidum bifite ireme, kuko kugenzura ibipimo ngenderwaho byibigo bishobora kurinda umutekano kandi efficacy yibicuruzwa kuva kumurongo kugeza kubitunganya.Kugenzura ubuziranenge busanzwe birashobora gukora ibicuruzwa bituma umubiri wumuntu ugira ubuzima bwiza.
 
Reba
1. Sliva D, n'abandi.Ibihumyo Ganoderma lucidum irinda kanseri ifitanye isano na kanseri yo mu mbeba.PLoS Umwe.2012; 7 (10): e47873.
2. Liu C, n'abandi.Ingaruka zo Kurwanya Indwara ya Ganoderma lucidumTriterpenoid mu ndwara ya Crohn yumuntu ifitanye isano no kugabanya ibimenyetso bya NF-κB.Gutwika Amara Dis.2015 Kanama; 21 (8): 1918-25.
3. Hanaoka R, n'abandi.Amazi ashonga mumazi yumuco wa Ganoderma lucidum (Reishi) mycelia (Yagizwe MAK) ahindura kolite murine iterwa na trinitrobenzenesulphonicacid.Scand J Immunol.2011 Ugushyingo; 74 (5): 454-62.

4. Nagai K, n'abandi.Polysaccharide ikomoka kuri Ganoderma lucidum fungus mycelia ameliorate indomethacin iterwa no gukomeretsa mu mara mato binyuze mu kwinjiza GM-CSF muri macrophage.Akagari Immunol.2017 Ukwakira; 320: 20-28.

Ibyerekeye umwanditsi / Madamu Wu Tingyao
Wu Tingyao yagiye atanga amakuru ku makuru ya Ganoderma lucidum kuva mu 1999. Ni umwanditsi wa “Ganoderma lucidum: Ingenious Beyond Description” (yasohotse mu gitabo cy’ubuvuzi cy’ubuvuzi muri Mata 2017).

★ Iyi ngingo yasohowe uruhushya rwihariye rwumwanditsi, kandi nyirubwite ni iya GANOHERB works Ibikorwa byavuzwe haruguru ntibishobora kubyara, gucibwa cyangwa gukoreshwa mubundi buryo butabiherewe uburenganzira na GanoHerb ★ Niba imirimo yemerewe gukoreshwa, barayikoresheje bigomba gukoreshwa muburyo bwo gutanga uburenganzira no kwerekana inkomoko: GanoHerb ★ Kurenga ku magambo yavuzwe haruguru, GanoHerb izakurikirana inshingano zijyanye n'amategeko.

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