Umahluko omkhulu phakathiLingzhi(ekwabizwa ngokubaI-Ganoderma lucidumokanye i-Reishi mushroom) okanye amayeza e-Lingzhi kunye nokunye ukutya okuninzi okunempilo kukuba ekubeni i-Lingzhi iyasebenza kwizinyanya kunye noluntu ngokubanzi oluyityileyo ukususela kumaxesha amandulo ukuza kuthi ga ngoku, izazinzulu zisebenzisa iimvavanyo zezilwanyana kunye neeseli ukuqonda ukuba kutheni i-Lingzhi isebenzayo endaweni ukumema uluntu ukuba luthenge iqhekeza lengqondo emva kokufumanisa amandla onyango e-Lingzhi kwiiseli kunye novavanyo lwezilwanyana.

Kuyafana nakwiLingzhi kwizicelo ezichasene nethumba.Ke ngoko, uphando lwezazinzulu malunga nempembelelo ye-anti-tumor ye-Lingzhi inokuqhubeka nokwenza izinto ezintsha kumazwe kwihlabathi liphela iminyaka engaphezu kwama-50 ukusukela ngo-1986 xa ingxelo yokuqala yophando ebonakalise impembelelo ye-anti-tumor ye-Lingzhi yapapashwa ngokwembali yiSizwe. Iziko loPhando lweCancer laseJapan.

Wonke umntu kufuneka ukuba ulufundile uphando oluninzi malunga nendlela uLingzhi anokuthi alwe ngayo umhlaza wemiphunga, umhlaza wesibindi, umhlaza wamathumbu kunye nomhlaza wamabele emzimbeni, kodwa ngaba uyazi ukuba uLingzhi unokulwa nomhlaza wesisu?!

Ingxelo epapashwe kwiiMolekyuli nguNjingalwazi onguNjingalwazi uHyo Jeung Kang, iKyungpook National University yeKholeji yezoKhemesti ngo-Okthobha ka-2019, yaqinisekisa ukuba i-triterpenoid-rich.I-Ganoderma lucidumisiqhamo somzimba we-ethanol extract (ebizwa ngokuba yi-GLE kolu phononongo) inokuthintela ukukhula kwamathumba egastric emzimbeni.

Isiphumo seI-Ganoderma lucidumithamo

Abaphandi baqala bafakela imigca yeeseli zomhlaza wesisu somntu kwimiva yeempuku ezibuthathaka (iimpuku ezinqunu).Emva kweeveki ezimbini zokukhula kwethumba, iimpuku zalawulwa ngomlomoI-Ganoderma lucidumi-ethanol extract GLE kwi-dose yemihla ngemihla ye-30 mg / kg.

Xa uvavanyo luqhubela phambili ukuya kumhla wama-23, izinga lokukhula kwethumbaI-Ganoderma lucidumiqela (i-curve eluhlaza kwi-Fig. 1) ngokucacileyo yayicotha kakhulu kuneqela lokulawula (i-curve emnyama kwi-Fig. 1) engazange ifumane unyango.

Umzobo 1 Idosi ephezuluI-Ganoderma lucidumi-ethanol extract inokuthintela ukukhula kwamathumba esisu

Nangona kunjalo, ukuba iI-Ganoderma lucidumisicatshulwa se-ethanolI-GLE elawulwa ngomlomo kwiimpuku iyancipha ukuya kwisinye kwisithathu, okt kuphela i-10 mg / kg ngosuku, izinga lokukhula kwethumbaI-Ganoderma lucidumiqela (i-curve eluhlaza kwi-Figure 2) imalunga nokufana neqela elingaphathwanga (i-curve emnyama kuMfanekiso 2).

Umzobo 2 Idosi ephantsiI-Ganoderma lucidumi-ethanol extract ayikwazi ukuthintela ukukhula kwamathumba esisu

Ngamanye amazwi, emva kweI-Ganoderma lucidum Isicatshulwa se-ethanol siyagaywa kwaye sifakwe kwindlela yesisu, sinokunqanda amathumba e-gastric kwi-immune-deficient body, kodwa esi siphumo sisekelwe, oko kukuthi, idosi kufuneka yanele;xa ithamo lingonelanga, kunokubakho isiphelo sokuba "ukutya i-Lingzhi kungasebenzi".

Isiphumo sesinye dibanisa enye asiyomfuneko ukuba sibe sikhulu kunesibini.

Olu pho nonongo luphinde lwaxubusha umphumo we-synergistic we-quercetin (QCT, i-flavonoid efumaneka ngokubanzi kwiziqhamo ezahlukeneyo, imifuno kunye neeti) kunyeI-Ganoderma lucidumi-ethanol extract in inhibiting tumors gastric.

Umsebenzi we-antioxidant we-quercetin unika inxalenye yesiseko sesayensi "ukutya okwaneleyo kweziqhamo kunye nemifuno kunokunciphisa umngcipheko womhlaza".Ngoko ke, ukudibanisa kwe-quercetin kunyeI-Ganoderma lucidumkufuneka ikwazi ukudlala indima yesinye dibanisa enye enkulu kunesibini, akunjalo?

Ukuba uzimisele ukujonga emva kwiziphumo zovavanyo lwezilwanyana ezichazwe kwiMifanekiso 1 kunye ne-2, akunzima ukufumana loo mpembelelo yedosi ephezulu (30 mg / kg nganye) ye "I-Ganodermalucidum+ iquercetin” ayilunganga kunokusebenzisa enye yazo yodwa.Nangona isiphumo sedosi ephantsi (10 mg/kg nganye) ye “I-Ganodermalucidum+ quercetin” ingcono kunokusebenzisa idosi ephantsiI-Ganoderma lucidumyedwa okanye ukusebenzisa idosi ephantsi ye-quercetin yodwa, esi siphumo silungileyo asihlukanga kwisiphumo “sokusebenzisa idosi ephezulu.I-Ganodermalucidumyedwa”.

Oko kukuthi, ukusuka kwindawo yokujonga indalo yomntu, sihlala sifuna "ukongeza into" ukuphucula umphumo wokuchasana nomhlaza.I-Ganoderma lucidum.Nangona kunjalo, kwiziphumo zenzululwazi, ukudibanisa okufana noku ngasentla akunakuba kuhle "njengokutya i-Ganoderma lucidum yodwa".Ukuthathwa rhoqo kweI-Ganoderma lucidumkunye nokutya okufanelekileyo kwemihla ngemihla kunokunceda imizimba yethu iphuhlise amandla alungileyo okuchasa umhlaza wokuziphilisa.

Intsholongwane ka-Epstein-Barr enokuhlala ngoxolo okanye ibangele umhlaza

Kufanelekile ukukhankanya ukuba umgca weseli yomhlaza wesisu somntu i-MKN1-EBV esetyenziswe kuvavanyo lwezilwanyana olukhankanywe ngasentla yiseli yomhlaza wesisu kunye ne-Epstein-Barr virus (EBV).Malunga ne-10% yezigulane ezinomhlaza wesisu zikolu hlobo lomhlaza wesisu onxulumene nentsholongwane ye-EB “enokuvavanywa ukuba unayo intsholongwane ye-EB kwizihlunu zomhlaza”.

Enyanisweni, abaninzi abantu abadala baye bosulelwa yintsholongwane ye-Epstein-Barr bengayazi, kuba xa ihlasela iiseli ze-B kwizicubu ze-mucosal ngokusebenzisa i-oral mucosa (amathe), iya kuzifihla kwiiseli ze-B kwindawo yokulala kwaye ihlale kunye. ngoxolo nomntu osulelekileyo ubomi bonke.

Kuphela inani elincinci labantu eliya kuba nomhlaza wesisu, umhlaza we-nasopharyngeal okanye i-lymphoma ngenxa ye-virus ye-Epstein-Barr.Ukungonelanga kokhuselo lomzimba ngundoqo kwintsholongwane ye-Epstein-Barr ukuphula ulungelelwaniso kunye nokwenza umhlaza.

Ke ngoko, kukho iintsholongwane ezininzi ekufuneka abantu bafunde ukuhlala ngoxolo nazo!Ukuze ube seluxolweni naba bahlaseli ngaxeshanye, eyona ndlela ilula kukugcina impilo kunyeI-Ganoderma lucidumngokubaI-Ganoderma lucidumiqulethe zombini i-polysaccharides enokulawula i-immunity kunye ne-triterpenes enokuthintela ukwanda kwentsholongwane.

Xa umhlaza usenzeka ngelishwa, kungcono ukutyaI-Ganoderma lucidumkuba ngeli xesha umzimba awufuni kuphela iipolysaccharides ukomeleza amajoni omzimba ukulwa neeseli zomhlaza kodwa ufuna ii-triterpenes ukulwa ngqo neeseli zomhlaza.

Uphononongo olukhankanywe ngasentla lwaseKorea lubonise ukuba i-triterpene-richI-Ganoderma lucidumIsicatshulwa se-ethanol sinokunqanda ukukhula kwe-Epstein-Barr yesisu esinxulumene nentsholongwane emzimbeni ngokuchanekileyo kuba inokubangela intsholongwane kwiiseli zomhlaza ukuba iwise iiseli zomhlaza ngaphandle kokwenza ingozi kwiiseli eziqhelekileyo.Phakathi kwabo, isithako esiphambili esikhokela "umlo ochasene netyhefu enetyhefu" yi-ganoderic acid A kwi-triterpeneI-Ganoderma lucidum.

NgelixaI-Ganoderma lucidumi-triterpenes efana ne-ganoderic acid A iya ngaphambili ukubulala utshaba,I-Ganoderma lucidumiipolysaccharides zikhathalela ngasemva ngokunyusa amajoni omzimba.Ngaba akuqinisekanga ngakumbi ukuphumelela uloyiso oluhle?

Ngoko sinokufunda kwaye sihlolisise izithako ezahlukeneyoI-Ganoderma lucidum.Kodwa xa kutyiwaI-Ganoderma lucidum, qiniseka ukuba ukhethaI-Ganoderma lucidumngezithako ezipheleleyo ezisebenzayo.Kuphela enjaloI-Ganoderma luciduminokulinganisa umgca wangaphambili kunye nommandla ongasemva kwaye ufezekise umphumo oyifunayo.

[Umthombo weDatha]

Sora Huh, et al.I-Quercetin I-Synergistically Inhibit EBV-Associated Gastric Carcinoma kunye ne-Ganoderma lucidum Extracts.Iimolekyuli.2019 Okt 24;24 (21): 3834. doi: 10.3390/molecules24213834. (https://www.mdpi.com/1420-3049/24/21/3834)

ISIPHELO

Malunga nombhali/ Nksz. Wu Tingyao

UWu Tingyao unike ingxelo ngolwazi lweGanoderma lokuqala ukusukela ngo-1999. Ungumbhali wencwadiUkunyanga ngeGanoderma(ipapashwe kwiNdlu yePeople's Medical Publishing House ngo-Epreli 2017).

★ Eli nqaku lipapashwa phantsi kogunyaziso olukhethekileyo lombhali, kwaye ubunini bubo be-GANOHERB ★ Le misebenzi ingentla ayinakuphinda iphinde iphinde iphinde iphinde isetyenziswe, ikhutshwe okanye isetyenziswe ngezinye iindlela ngaphandle kogunyaziso lweGanoHerb ★ Ukuba imisebenzi igunyazisiwe ukuba isetyenziswe, kufuneka isetyenziswe ngaphakathi kwendawo yogunyaziso kwaye ibonise umthombo: GanoHerb ★ Ukwaphulwa kwengxelo engentla, iGanoHerb iya kulandela uxanduva lwayo olusemthethweni oluhambelanayo ★ Umbhalo wokuqala weli nqaku ubhalwe ngesiTshayina nguWu Tingyao kwaye waguqulelwa kwisiNgesi nguAlfred Liu.Ukuba kukho nakuphi na ukungangqinelani phakathi kwenguqulelo (isiNgesi) kunye neyoqobo (isiTshayina), isiTshayina sokuqala siya koyisa.Ukuba abafundi banayo nayiphi na imibuzo, nceda uqhagamshelane nombhali wokuqala, uNks. Wu Tingyao.

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