Kusiyana kwakukulu pakatiLingzhi(amatchedwansoGanoderma lucidumkapena bowa wa Reishi) kapena mankhwala a Lingzhi ndi zakudya zina zambiri zathanzi ndikuti popeza Lingzhi ndi yothandiza kwa makolo ndi anthu wamba omwe adadya kuyambira nthawi zakale mpaka pano, asayansi amagwiritsa ntchito kuyesa kwa nyama ndi maselo kuti amvetsetse chifukwa chake Lingzhi ndi yothandiza m'malo mwake. kuitana anthu kuti agule malingaliro atazindikira kuthekera kwamankhwala kwa Lingzhi mu kuyesa kwa ma cell ndi nyama.

N'chimodzimodzinso ndi Lingzhi mu ntchito zotsutsana ndi chotupa.Chifukwa chake, kafukufuku wa asayansi pa zotsutsana ndi zotupa za Lingzhi zitha kupitiliza kupanga m'maiko padziko lonse lapansi kwazaka zopitilira 50 kuyambira 1986, pomwe lipoti loyamba lofufuza lomwe lidatsimikizira kuti Lingzhi anti-chotupa lidasindikizidwa kale ndi National. Cancer Center Research Institute ku Japan.

Aliyense ayenera kuti adawerenga kafukufuku wambiri momwe Lingzhi angathanirane ndi khansa ya m'mapapo, khansa ya chiwindi, khansa ya m'mimba ndi khansa ya m'mawere m'thupi, koma kodi mumadziwa kuti Lingzhi amathanso kulimbana ndi khansa ya m'mimba?!

Lipoti lofalitsidwa mu Molecules ndi Wothandizira Pulofesa Hyo Jeung Kang, Kyungpook National University's College of Pharmacy mu Okutobala 2019, adatsimikiza kuti olemera a triterpenoid.Ganoderma lucidumfruiting body ethanol extract (yotchedwa GLE mu phunziroli) imatha Kulepheretsa kukula kwa zotupa zam'mimba m'thupi.

Zotsatira zaGanoderma lucidummlingo

Ofufuzawo adayikapo mizere ya khansa ya m'mimba ya anthu kumbuyo kwa mbewa zopanda chitetezo (mbewa zamaliseche).Patapita milungu iwiri chotupa kukula, mbewa anapatsidwa pakamwa ndiGanoderma lucidumEthanol Tingafinye GLE pa mlingo tsiku 30 mg/kg.

Pamene kuyesa kudapitilira mpaka tsiku la 23, kuchuluka kwa chotupa kukukula kwaGanoderma lucidumgulu (mzere wobiriwira mu mkuyu 1) mwachiwonekere unali wocheperapo kusiyana ndi gulu lolamulira (mtundu wakuda mu Fig. 1) umene sunalandire chithandizo chilichonse.

Chithunzi 1 Mlingo wambiriGanoderma lucidumMowa Tingafinye zingalepheretse kukula kwa chapamimba zotupa

Komabe, ngatiGanoderma lucidumethanol kuchotsaGLE yoperekedwa pakamwa kwa mbewa imachepetsedwa kufika pa gawo limodzi mwa magawo atatu, mwachitsanzo 10 mg/kg patsiku, kuchuluka kwa chotupa cha mbewa.Ganoderma lucidumgulu (mzere wobiriwira mu Chithunzi 2) ndi ofanana ndi gulu lolamulira losagwiritsidwa ntchito (mtundu wakuda mu Chithunzi 2).

Chithunzi 2 Mlingo wochepaGanoderma lucidumMowa Tingafinye sangalepheretse kukula kwa chapamimba zotupa

M'mawu ena, pambuyo paGanoderma lucidum Mowa Tingafinye ndi digested ndi odzipereka mu m`mimba thirakiti, izo ndithu ziletsa chapamimba zotupa mu chitetezo akusowa thupi, koma zimenezi ndi premised, ndiko kuti, mlingo ayenera kukhala wokwanira;kamodzi mlingo uli wosakwanira, pakhoza kukhala mapeto kuti "kudya Lingzhi sikuthandiza".

Zotsatira za kuphatikizika kumodzi sizikhala zazikulu kuposa ziwiri.

Kafukufukuyu adakambirananso za synergistic zotsatira za quercetin (QCT, flavonoid yomwe imapezeka mu zipatso zosiyanasiyana, masamba ndi tiyi) ndiGanoderma lucidumKutulutsa kwa ethanol poletsa zotupa zam'mimba.

Ntchito ya antioxidant ya quercetin imapereka gawo la maziko a sayansi kuti "kudya mokwanira kwa zipatso ndi ndiwo zamasamba kungachepetse chiopsezo cha khansa".Chifukwa chake, kuphatikiza kwa quercetin ndiGanoderma lucidumayenera kukhala ndi gawo la chimodzi kuphatikiza chimodzi chachikulu kuposa ziwiri, sichoncho?

Ngati mukulolera kuyang'ana m'mbuyo pa zotsatira za kuyesa kwa zinyama zomwe zaperekedwa mu Zithunzi 1 ndi 2, sizovuta kupeza zotsatira za mlingo waukulu (30 mg / kg aliyense) wa "Ganodermalucidum+ quercetin” si bwino kuposa kugwiritsa ntchito imodzi mwa izo yokha.Ngakhale zotsatira za mlingo wochepa (10 mg / kg aliyense) wa "Ganodermalucidum+ quercetin” ndi yabwino kuposa kugwiritsa ntchito mlingo wochepaGanoderma lucidumpaokha kapena kugwiritsa ntchito mlingo wochepa wa quercetin wokha, zotsatira zabwinozi sizosiyana ndi zotsatira za "kugwiritsa ntchito mlingo waukulu.Ganodermalucidumyekha”.

Ndiko kunena kuti, kuchokera pamalingaliro aumunthu, nthawi zonse timafuna "kuwonjezera china" kuti tipititse patsogolo zotsutsana ndi khansa.Ganoderma lucidum.Komabe, kuchokera ku zotsatira za sayansi, kuphatikiza kofanana ndi pamwambapa sikungakhale bwino monga "kudya Ganoderma lucidum yekha".Kudya pafupipafupi kwaGanoderma lucidumkuphatikiza zakudya zoyenera zatsiku ndi tsiku zingathandize thupi lathu kukhala ndi mphamvu yodzichiritsa yokha yolimbana ndi khansa.

Epstein-Barr virus yomwe imatha kukhala mwamtendere kapena kuyambitsa khansa

Ndikoyenera kutchula kuti cell ya khansa ya m'mimba ya munthu MKN1-EBV yomwe imagwiritsidwa ntchito poyesa nyama yomwe tatchulayi ndi cell ya khansa ya m'mimba yokhala ndi kachilombo ka Epstein-Barr (EBV).Pafupifupi 10% ya odwala omwe ali ndi khansa ya m'mimba ali a mtundu uwu wa khansa ya m'mimba ya EB yokhudzana ndi kachilombo ka HIV yomwe "imatha kuyesedwa kuti ili ndi kachilombo ka EB m'magulu a khansa".

Ndipotu, achikulire ambiri ali ndi kachilombo ka Epstein-Barr popanda kudziwa, chifukwa pamene alowa mu B cell mucosal minofu kudzera mumphuno yapakamwa (malovu), imabisala m'maselo a B m'malo ogona ndikukhala pamodzi. mwamtendere ndi munthuyo kwa moyo wake wonse.

Ndi anthu ochepa okha omwe adzadwala khansa ya m'mimba, khansa ya m'mphuno kapena lymphoma chifukwa cha kachilombo ka Epstein-Barr.Kusagwira ntchito mokwanira kwa chitetezo chamthupi ndiye chinsinsi cha kachilombo ka Epstein-Barr kuti aswe bwino ndikuyambitsa khansa.

Chifukwa chake, pali ma virus angapo omwe anthu amayenera kuphunzira kukhala nawo mwamtendere!Kukhala pamtendere ndi owukirawa nthawi yomweyo, chophweka njira ndi kukhala ndi thanzi ndiGanoderma lucidumchifukwaGanoderma lucidumlili ndi ma polysaccharides omwe amatha kuwongolera chitetezo chokwanira komanso ma triterpenes omwe amatha kuletsa kuchulukana kwa ma virus.

Khansara ikachitika mwatsoka, ndi bwino kudyaGanoderma lucidumchifukwa panthawiyi thupi silimangofunika ma polysaccharides kuti apititse patsogolo chitetezo chamthupi kuti amenyane ndi maselo a khansa komanso amafunika triterpenes kuti athane ndi maselo a khansa.

Maphunziro aku Korea omwe tawatchulawa atsimikizira kuti olemera a triterpeneGanoderma lucidumTingafinye ethanol akhoza ziletsa kukula kwa Epstein-Barr HIV zokhudzana ndi chotupa chapamimba mu thupi ndendende chifukwa akhoza kuyambitsa kachilombo ka khansa maselo kugwa maselo a khansa popanda kuvulaza maselo abwinobwino.Pakati pawo, chinthu chachikulu chomwe chimatsogolera "kulimbana ndi poizoni ndi poizoni" ndi ganoderic acid A mu triterpene ya.Ganoderma lucidum.

PameneGanoderma lucidumtriterpenes monga ganoderic acid A kupita kutsogolo kukapha mdani,Ganoderma lucidumma polysaccharides amasamalira kumbuyo polimbikitsa chitetezo chamthupi.Kodi sizotsimikizika kwambiri kuti tipambane mokongola?

Kotero ife tikhoza kuphunzira ndi kufufuza zinthu zosiyanasiyana zaGanoderma lucidum.Koma podyaGanoderma lucidum, onetsetsani kuti mwasankhaGanoderma lucidumndi zosakaniza zonse zogwira ntchito.ZokhazoGanoderma lucidumimatha kulinganiza mzere wakutsogolo ndi kumbuyo ndikukwaniritsa zomwe mukufuna.

[Magwero a Data]

Sora Huh, et al.Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma yokhala ndi Ganoderma lucidum Extracts.Mamolekyu.2019 Oct 24;24 (21): 3834. doi: 10.3390/molecules24213834. (https://www.mdpi.com/1420-3049/24/21/3834)

TSIRIZA

Za wolemba/ Mayi Wu Tingyao

Wu Tingyao wakhala akufotokoza zambiri za Ganoderma kuyambira 1999. Iye ndi mlembi wa bukuli.Kuchiza ndi Ganoderma(lofalitsidwa mu The People's Medical Publishing House mu April 2017).

★ Nkhaniyi yasindikizidwa pansi pa chilolezo cha wolemba, ndipo umwini ndi wa GANOHERB ★ Ntchito zomwe zili pamwambazi sizingapangidwenso, kuchotsedwa kapena kugwiritsidwa ntchito m'njira zina popanda chilolezo cha GanoHerb ★ Ngati ntchitozo zaloledwa kugwiritsidwa ntchito, iwo ziyenera kugwiritsidwa ntchito mkati mwa chilolezo ndikuwonetsa gwero: GanoHerb ★ Kuphwanya mawu omwe ali pamwambawa, GanoHerb idzakwaniritsa udindo wake wokhudzana ndi malamulo ★ Zolemba zoyambirira za nkhaniyi zinalembedwa m'Chitchaina ndi Wu Tingyao ndikumasuliridwa ku Chingerezi ndi Alfred Liu.Ngati pali kusiyana kulikonse pakati pa kumasulira (Chingerezi) ndi choyambirira (Chitchaina), Chitchaina choyambirira chidzapambana.Ngati owerenga ali ndi mafunso, lemberani wolemba woyamba, Mayi Wu Tingyao.

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