Farqiga ugu weyn ee u dhexeeyaLingzhi(sidoo kale loo yaqaanGanoderma lucidumama likaha Reishi) ama daawooyinka Lingzhi iyo cuntooyin kale oo badan oo caafimaad ayaa ah in maadaama Lingzhi waxtar u leeyahay awoowayaashii iyo dadweynihii cuni jiray wakhtiyadii hore ilaa hadda, saynisyahannadu waxay isticmaalaan tijaabooyinka xayawaanka iyo unugyada si ay u fahmaan sababta Lingzhi waxtar u leeyahay halkii ay ka ahaan lahaayeen. ku martiqaadida dadweynaha inay iibsadaan qayb maskaxeed ka dib markii la ogaaday awoodda dawo ee Lingzhi ee tijaabooyinka unugyada iyo xayawaanka.

Isla sidaas oo kale waa run Lingzhi ee codsiyada ka hortagga burooyinka.Sidaa darteed, cilmi-baaristii saynisyahannada ee saameynta anti-buro ee Lingzhi waxay sii wadi kartaa inay hal-abuurnimo ka sameeyaan waddamada adduunka oo dhan in ka badan 50 sano tan iyo 1986 markii warbixintii ugu horreysay ee cilmi-baaris ee caddaynaysa saameynta anti-buro ee Lingzhi ay taariikh ahaan daabacday National Machadka Cilmi-baarista Xarunta Kansarka ee Japan.

Qof walba waa inuu akhriyay cilmi baaris badan oo ku saabsan sida Lingzhi uu ula dagaallamo kansarka sambabada, kansarka beerka, kansarka mindhicirka iyo kansarka naasaha ee jirka, laakiin ma ogtahay in Lingzhi uu sidoo kale la dagaallami karo kansarka caloosha?!

Warbixin lagu daabacay Molecules oo uu qoray Associate Professor Hyo Jeung Kang, Kulliyadda Farmasiiga ee Jaamacadda Qaranka ee Kyungpook bishii Oktoobar 2019, ayaa xaqiijisay in triterpenoid-hodanGanoderma lucidumlaga soosaaray ethanol jirka midhaha (oo loo yaqaan GLE daraasaddan) waxay joojin kartaa koritaanka burooyinka gastric ee jirka.

SaamayntaGanoderma lucidumqiyaasta

Cilmi-baadhayaashu waxay markii ugu horreysay ku dhejiyeen khadadka unugyada kansarka caloosha ee bini'aadamka ee dhabarka jiirarka difaaca jirkooda (jiirarka qaawan).Ka dib laba toddobaad oo koritaanka burada, jiirarka ayaa afka lagu maamulayGanoderma lucidumSoosaarida ethanol GLE ee qiyaasta maalinlaha ah ee 30 mg/kg.

Markii ay tijaabadu u gudubtay maalintii 23aad, heerka koritaanka burada eeGanoderma lucidumkooxda (qallooca cagaaran ee Jaantuska 1) waxa cad in uu aad uga gaabnaa kan kooxda xakamaynta (qalooca madow ee Jaantuska 1) ee aan helin wax daaweyn ah.

Jaantuska 1-aad qiyaas sare lehGanoderma lucidumSoosaarka ethanol wuxuu joojin karaa koritaanka burooyinka caloosha

Si kastaba ha ahaatee, haddii ayGanoderma lucidumsoosaar ethanolGLE afka laga maareeyo jiirarka ayaa lagu dhimaa saddex meelood meel, tusaale kaliya 10 mg/kg maalintii, heerka koritaanka buradaGanoderma lucidumkooxda (qallooca cagaaran ee Jaantuska 2) wuxuu la mid yahay kan kooxda kantaroolka aan la daawayn ( qalooca madow ee Jaantuska 2).

Jaantuska 2 Qiyaas yarGanoderma lucidumSoosaarka ethanol ma joojin karo koritaanka burooyinka caloosha

Si kale haddii loo dhigo, ka dibGanoderma lucidum Soosaarida ethanol waa la dheefshiido oo lagu nuugo mareenka caloosha iyo mindhicirka, waxay runtii joojin kartaa burooyinka gastric ee difaaca jirka ee daciifka ah, laakiin saameyntani waa mid la diyaariyey, taas oo ah, qiyaasta waa inay ahaataa mid ku filan;mar haddii qiyaasta qiyaasta ay ku filnaan weydo, waxaa jiri kara dhammaanaya in "cunista Lingzhi aysan waxtar lahayn".

Saamaynta hal lagu daray maaha qasab in ka badan laba.

Daraasaddan ayaa sidoo kale ka hadashay saameynta isku-dhafka ah ee quercetin (QCT, flavonoid si ballaaran looga helo miraha, khudaarta iyo shaaha) iyoGanoderma lucidumSoosaarida ethanol ee ka hortagga burooyinka caloosha.

Waxqabadka antioxidant ee quercetin wuxuu bixiyaa qayb ka mid ah aasaaska sayniska ee "qaadashada ku filan ee miraha iyo khudaarta waxay yareyn kartaa halista kansarka".Sidaa darteed, isku dhafka quercetin iyoGanoderma lucidumwaa in uu ciyaari karaa doorka mid lagu daray mid ka weyn laba, sax?

Haddii aad diyaar u tahay inaad dib u eegto natiijooyinka tijaabooyinka xayawaanka ee lagu soo bandhigay jaantusyada 1 iyo 2, ma adka in la helo saameyntaas qiyaasta sare ah (30 mg / kg midkiiba) "Ganodermalucidum+ quercetin” kama roona isticmaalka mid ka mid ah kaligiis.In kasta oo saamaynta qiyaasta-yar (10 mg/kg kasta) ee "Ganodermalucidum+ quercetin” ayaa ka wanaagsan isticmaalka qiyaas yarGanoderma lucidumkeligiis ama isticmaalka quercetin-dose yar oo kali ah, saamayntan wanaagsani kama duwana saamaynta “adeegsiga qiyaasta sareGanodermalucidumkeligiis”.

Taas macnaheedu waa, marka laga eego aragtida dabeecadda aadanaha, waxaan had iyo jeer rabnaa inaan "ku darno wax" si loo hagaajiyo saameynta ka hortagga kansarka eeGanoderma lucidum.Si kastaba ha noqotee, natiijooyinka sayniska, isku-dhafka la midka ah ee kor ku xusan ayaa laga yaabaa inaysan u fiicnayn sida "cunida Ganoderma lucidum oo keliya".Qaadasho joogto ah oo ahGanoderma lucidumoo lagu daray cunto maalinle ah oo ku habboon ayaa ka caawin karta jidhkeenna inuu yeesho awood is-bogsiin fiican oo ka-hortagga kansarka.

Fayraska Epstein-Barr kaas oo si nabad ah ugu wada noolaan kara ama keeni kara kansar

Waxaa xusid mudan in xariiqda unugyada kansarka caloosha ee bini'aadamka ee MKN1-EBV loo isticmaalo tijaabada xayawaanka ee kor ku xusan waa unug kansar gastric ah oo leh fayraska Epstein-Barr (EBV).Ku dhawaad ​​10% bukaanada qaba kansarka caloosha waxa ay ka tirsan yihiin nooca kansarka caloosha ee fayraska EB-ga la xiriira kaas oo “lagu tijaabin karo fayraska EB ee unugyada kansarka”.

Dhab ahaantii, dadka waaweyn intooda badan waxaa ku dhacay fayraska Epstein-Barr iyaga oo aan garanaynin, sababtoo ah marka uu ku soo galo unugyada B ee unugyada xuubka xuubka xuubka afka (candhuufta), waxay ku dhuuman doontaa unugyada B ee xaalad hurdo ah oo wada noolaanshaha. si nabad ah ula nool qofka cudurka qaba inta nool oo dhan.

Kaliya tiro yar oo dad ah ayaa ku dhici doona kansarka caloosha, kansarka sanbabada ama lymfoma sababtoo ah fayraska Epstein-Barr.Shaqada difaaca oo aan ku filneyn ayaa fure u ah fayraska Epstein-Barr si uu u jebiyo dheellitirka oo uu keeno kansar.

Sidaa darteed, waxa jira fayrasyo ​​badan oo ay tahay in aadamigu barto si ay nabad ugu wada noolaadaan!Si aad nabad ula heshid kuwa soo duulay isla mar ahaantaana, sida ugu fudud waa in la ilaaliyo caafimaadkaGanoderma lucidumsababtoo ahGanoderma lucidumwaxaa ku jira labadaba polysaccharides kuwaas oo xakameyn kara difaaca iyo triterpenes kuwaas oo xakameyn kara faafitaanka fayraska.

Marka uu kansarku dhaco nasiib darro, waxa fiican in la cunoGanoderma lucidumsababtoo ah wakhtigan jidhku kaliya uma baahna polysaccharides si kor loogu qaado habka difaaca si uu ula dagaallamo unugyada kansarka laakiin sidoo kale wuxuu u baahan yahay triterpenes si uu si toos ah ula dagaallamo unugyada kansarka.

Daraasadaha kore ee kor ku xusan waxay caddeeyeen in triterpene-hodanGanoderma lucidumsoosaaray ethanol waxay joojin kartaa koritaanka Epstein-Barr fayraska la xiriira burooyinka caloosha ee jirka si sax ah sababtoo ah waxay kicin kartaa fayraska unugyada kansarka si ay u burburaan unugyada kansarka iyada oo aan waxyeello u geysan unugyada caadiga ah.Waxaa ka mid ah, walxaha ugu muhiimsan ee hagaya "la dagaalanka sunta leh" waa ganoderic acid A ee triterpeneGanoderma lucidum.

HalkaGanoderma lucidumtriterpenes sida ganoderic acid A tag hore si ay u dilaan cadowga,Ganoderma lucidumpolysaccharides waxay xanaaneeyaan dhabarka iyagoo kor u qaadaya habka difaaca jirka.Miyaanay hubaal ahayn inaad guul qurux badan ku guulaysato?

Markaa waxaan baran karnaa oo aan sahamin karnaa maaddooyinka kala duwan ee ay ka kooban yihiinGanoderma lucidum.Laakiin markaad wax cunaysoGanoderma lucidum, hubi inaad dooratoGanoderma lucidumoo leh maaddooyin firfircoon oo dhammaystiran.Kaliya sidaGanoderma lucidumwaxay isku dheellitiri kartaa safka hore iyo aagga dambe waxayna gaari kartaa saameynta la rabo.

[Isha Xogta]

Soora Huh, iyo al.Quercetin Synergistically Inhibit EBV-Associated Gastric Carcinoma oo leh Ganoderma lucidum Extracts.Unugyada.2019 Oktoobar 24;24 (21): 3834. doi: 10.3390/molecules24213834. (https://www.mdpi.com/1420-3049/24/21/3834)

DHAMAAD

Ku saabsan qoraaga/Ms. Wu Tingyao

Wu Tingyao waxa ay ka warbixinaysay macluumaadka Ganoderma ee gacanta koowaad tan iyo 1999. Iyadu waa qoraagaKu bogsashada Ganoderma(waxaa lagu daabacay Guriga Daabacaada Caafimaadka Dadweynaha Abriil 2017).

★ Maqaalkan waxa lagu daabacay ogolaansho gaar ah oo uu leeyahay qoraaga, lahaanshahana waxaa iska leh GANOHERB ★ Shaqooyinka kor ku xusan lama soo saari karo, lama saari karo, lamana isticmaali karo siyaabo kale iyada oo aan fasax laga helin GanoHerb ★ Haddii shaqooyinka loo oggolaaday in la isticmaalo, waa in loo istcimaalaa inta ay le'egtahay oggolaanshaha oo tilmaama isha: GanoHerb ★ Ku xad-gudbida bayaanka sare, GanoHerb waxay sii wadi doontaa mas'uuliyadeeda sharci ee la xidhiidha ★ Qoraalka asalka ah ee maqaalkan waxaa ku qoray Shiinaha Wu Tingyao waxaana u tarjumay Ingiriisi Alfred Liu.Haddii uu jiro farqi u dhexeeya tarjumaada (Ingiriiska) iyo kan asalka ah (Shiineyska), Shiinaha asalka ah ayaa guulaysan doona.Haddii akhristayaasha ay qabaan wax su'aalo ah, fadlan la xiriir qoraaga asalka ah, Ms. Wu Tingyao.

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