January 8, 2016/ Chinese Academy of Medical Sciences ndi Peking Union Medical College/ Frontiers in Microbiology

Mawu/Wu Tingyao

Muyenera kuti munaonapo munthu wina womvetsa chisoni m’sewerolo yemwe anakhosomola kwa nthawi yaitali moti anatsokomola magazi ochuluka m’kamwa mwake mwa chifuwa chake chachikulu...... ena.Ndi kulowerera koyambirira kwamankhwala amakono, anthu ochepa adadwala kwambiri, koma wolakwayo,Mycobacterium chifuwa chachikulu, anali okonzeka kuterokuyambitsa chachikulukuukira pamene chitetezo cha m'thupi chawonongeka.Tsopano, kuchokera ku China kunabwera uthenga wabwino umenewoGanoderma lucidum spores ndi sporelipids akhoza kuletsa prophylacticallyMycobacterium chifuwa chachikulu.

Kafukufuku wofalitsidwa ndi Chinese Academy of Medical Sciences ndi Peking Union Medical College mu "Frontiers in Microbiology" mu Januwale 2016 adanena kuti kayendetsedwe ka chitetezo chaGanoderma lucidum kuchotsa (spores ndi sporelipids)imatha kulepheretsa kubwereza ndi kuchulukana kwaMycobacterium chifuwa chachikulu mu mbewa ndi kuchepetsa chiwerengero chaMycobacterium chifuwa chachikulu m'mapapo ndi ndulu ya mbewa.

Matenda onse oyambitsidwa ndiMycobacterium chifuwa chachikulu onse pamodzi amatchedwa "TB".Mycobacterium chifuwa chachikulu imafalitsidwa makamaka kudzera m'malovu.Ndi matenda opatsirana kwambiri m'malo otsekeka komanso kutali.Minofu ndi ziwalo zilizonse m'thupi lathu zitha kutenga kachilomboka.Komabe,“TB” yoyambitsidwa ndi matenda a m’mapapo ndiyo yofala kwambiri.Anthu omwe ali ndi chifuwa chachikulu cha TB adzafa chifukwa cha kuwonongeka kwa mapapo awo.

Kutengera ziwerengero za ku Taiwan mu 2012 monga mwachitsanzo, chiwerengero cha anthu omwe anamwalira chifukwa cha chifuwa chachikulu m'chaka chimenecho chinali choposa 600, chomwe chinali kuwirikiza kakhumi chiwerengero cha anthu omwe amafa ndi SARS mu 2003. SARS imabwera kamodzi, koma chifuwa chachikulu chimakhalapo nthawi zonse. .Akuti chifuwa cha TB sichinathe kuyambira kalekaleNeolithic Zaka.Ngakhale kupangidwa kwa BCG kunawongolera kukula kwa matenda, sikunatsekeretu kuopsa kwa chifuwa chachikulu kwa anthu.Tiyenera kukhala osamalamotsutsa izo.

Musaganize kuti chifuwa chachikulu sichikukhudzana ndi inu.Zikumveka kuti pafupifupi gawo limodzi mwa magawo atatu a anthu padziko lonse lapansi ali ndi matenda a chifuwa chachikulu.Inu ndi ine tikhoza kukhala mmodzi wa iwo.Kungoti anthu ambiri omwe ali ndi kachilomboka alibe zizindikiro (kutsokomola kwa nthawi yopitilira mwezi umodzi, kuchepa thupi, kutentha thupi komanso kutuluka thukuta usiku) komanso “matenda a chifuwa chachikulu chodziwikiratu” osapatsirana.

Ndipotu, malinga ngati chitetezo chokwanira chikukwanira,Mycobacterium chifuwa chachikulu ikhoza kusungidwa mumkhalidwe "wosagwira ntchito".Vuto ndilakuti chitetezo cha mthupi chikalowa m'mavuto, makamaka polandira chithandizo cha radiotherapy, chemotherapy, kapena kutenga kachilombo ka HIV.Mycobacterium chifuwa chachikulu akhoza kukhala ndi mwayi waukulu woukira.Choncho, mmene kupewa matenda ndi mmene bwino kupondereza pambuyo matenda ndi cholinga cha kupewa ndi kuchiza chifuwa chachikulu.

Gulu lofufuza la Chinese Academy of Medical Sciences ndi Peking Union Medical College lidayamba kugwiritsa ntchito mbewa za C57BL/6 ndi mbewa zochepa.Mycobacterium chifuwa chachikulu kuti akhazikitse chitsanzo choyesera nyama chofanana ndi "matenda a chifuwa chachikulu" cha anthu, ndikuwunikanso zotsatira za anti-TBGanoderma lucidum.Timuyi idapeza kuti:

Pamene mbewa zinali ndi matendaMycobacterium chifuwa chachikulu, iwo anathandizidwa nthawi imodziGanoderma lucidum kukonzekera (15 mg wa spores ndi 15 mg wa sporelipid anatengedwa pakamwa tsiku lililonse kwa masabata 16, ndiye kuyesa kunatha), chiwerengero chaMycobacterium chifuwa chachikulu m'mapapo ndi ndulu ya mbewa sizinasiyane ndi zomwe zili m'gulu losachiritsidwa.Komabe, ngati mlingo womwewo waGanoderma lucidum angaperekedwe kwa mbewa mwezi umodzi asanayambe kuyesa (matenda), akhoza kuchepetsa chiwerengero chaMycobacterium chifuwa chachikulu m'mapapo ndi ndulu ya mbewa.Makamaka mu masabata atatu kapena asanu oyambirira pameneMycobacterium chifuwa chachikulu amalowa m'thupi la mbewa, zotsatira zolepheretsa ndizofunika kwambiri.

Zinawonedwanso pakuyesa kuti panalibe kulumikizana pakati pa kuchuluka kwa maselo oteteza chitetezo m'magazi ozungulira a mbewa, kuchuluka kwa kuchuluka kwa mbewa.Mycobacterium chifuwa chachikulu, komanso kukula kwa zotupa za m'mapapo ndi ndulu.Komabe, mu mbewa zimene ankadyaGanoderma lucidum Kukonzekera pamaso pa matenda, patatha milungu itatu kapena isanu mutadwala chifuwa chachikulu cha Mycobacterium, maselo a dendritic m'magazi ozungulira amachepa kwambiri, ndipo maselo a dendritic m'mapapo amawonjezeka kwambiri.Chodabwitsa ichi chikhoza kufotokoza chifukwa chake kudya musanadyeGanoderma lucidum akhoza kuletsaMycobacterium chifuwa chachikulu m'mapapu a mbewa.

[Chitsime]Zhan L, ndi al.Kugwiritsa ntchito prophylactic kwa chotsitsa cha Ganoderma lucidum kungalepheretse kubwereza kwa Mycobacterium TB mu mtundu watsopano wa mbewa wa matenda a chifuwa chachikulu chodziwikiratu.Front Microbiol.2016 Jan 8; 6:1490.doi: 10.3389/fmicb.2015.01490.eCollection 2015.

TSIRIZA

Za wolemba/ Mayi Wu Tingyao

Wu Tingyao wakhala akunena za zomwe zikuchitikaGanoderma lucidumzambiri kuyambira 1999. Iye ndi mlembi waKuchiza ndi Ganoderma(lofalitsidwa mu The People's Medical Publishing House mu April 2017).

★ Nkhaniyi yasindikizidwa ndi chilolezo cha mlembi ★ Ntchito zomwe zili pamwambazi sizingabwerezedwe, kutsanulidwa kapena kugwiritsidwa ntchito mwanjira ina popanda chilolezo cha wolemba ★ Kuphwanya mawu omwe ali pamwambawa, wolemba adzakwaniritsa udindo wake wazamalamulo ★ Zoyambirira Nkhaniyi idalembedwa m'Chitchaina ndi Wu Tingyao ndikumasuliridwa m'Chingerezi ndi Alfred Liu.Ngati pali kusiyana kulikonse pakati pa kumasulira (Chingerezi) ndi choyambirira (Chitchaina), Chitchaina choyambirira chidzapambana.Ngati owerenga ali ndi mafunso, lemberani wolemba woyamba, Mayi Wu Tingyao.