Jenụwarị 8, 2016/ Ụlọ akwụkwọ sayensị China nke sayensị na ahụike na Peking Union Medical College/ Frontiers in Microbiology

Ederede/Wu Tingyao

Ọ ga-abụrịrị na ị hụla ụfọdụ agwa jọgburu onwe ya na egwuregwu nke kwara ụkwara ogologo oge nke mere na ọ kwara ọnụ ọbara n'otu n'ime nnukwu ụkwara ya……Achọpụtara ya na ọ nwere ụkwara nta wee nọpụ ya iche ka ọ ghara ịgbasa ọrịa ahụ. ndị ọzọ.Site na ntinye aka mbụ nke ọgwụ ọgbara ọhụrụ, mmadụ ole na ole dara ọrịa, mana onye kpatara ya.Mụkwara nta ycobacterium, dị njikeremalite nnukwuọgụ mgbe usoro ahụ ji alụso ọrịa ọgụ na-emebi.Ugbu a, ozi ọma ahụ si China bịaGanoderma lucidum spores na sporelipids nwere ike igbochi prophylacticMụkwara nta ycobacterium.

Otu nnyocha nke Chinese Academy of Medical Sciences na Peking Union Medical College bipụtara na "Frontiers in Microbiology" na Jenụwarị 2016 gosiri na nchịkwa mgbochi nkeGanoderma lucidum wepụ (spores na sporelipid)nwere ike igbochi mmeghari na mmụba nkeMycobacterium ụkwara nta na ụmụ oke ma belata ọnụ ọgụgụ nkeMycobacterium ụkwara nta na ngụgụ na splin nke oke.

Ọrịa niile kpataraMycobacterium ụkwara nta a na-akpọkọta ọnụ dị ka "ụkwara nta".Mycobacterium ụkwara nta a na-ebutekarị site na ụmụ irighiri mmiri.Ọ na-efe efe nke ukwuu n'ime oghere na ebe dị anya.Anụ ahụ na akụkụ ọ bụla dị n'ahụ anyị nwere ike ibute ọrịa.Agbanyeghị,"ụkwara nta" nke ọrịa ngụgụ na-ebute bụ nke a na-ahụkarị.Ndị nwere ụkwara nta siri ike ga-anwụ n'ihi mmebi nke ngụgụ ha.

N'iburu ọnụ ọgụgụ nke Taiwan na 2012 dị ka ihe atụ, ọnụ ọgụgụ ndị nwụrụ n'ihi ụkwara nta n'afọ ahụ karịrị 600, nke ji okpukpu iri karịa ọnụ ọgụgụ ndị SARS nwụrụ na 2003. SARS na-abịa otu ugboro mgbe ụfọdụ, mana ụkwara nta na-adị mgbe niile. .A na-ekwu na ụkwara nta akwụsịbeghị kemgbe oge ochieNeolithic Afọ.Ọbụlagodi na ihe mepụtara BCG na-achịkwa ọnụ ọgụgụ nke ọrịa, mana ọ ka gbochiri kpamkpam ihe egwu ụkwara nta na-emetụta ụmụ mmadụ.Anyị ga-akpachara anyamegide ya.

Echela na ụkwara nta enweghị ihe jikọrọ gị na gị.Aghọtara na ihe ruru otu ụzọ n'ụzọ atọ nke ndị bi n'ụwa niile bu ụkwara nta.Mụ na gị nwere ike ịbụ otu n'ime ha.Ọ bụ naanị na ihe ka ọtụtụ n'ime ndị butere ọrịa ahụ enweghị ihe mgbaàmà (ụkwara ogologo oge karịa otu ọnwa, oke ibu, ahụ ọkụ na ọsụsọ abalị) yana obere ọrịa “ọrịa ụkwara nta” na-efe efe.

N'ezie, ọ bụrụhaala na mgbochi ahụ zuru oke.Mycobacterium ụkwara nta enwere ike idowe ya n'ọnọdụ "adịghị arụ ọrụ".Nsogbu bụ na mgbe usoro ahụ ji alụso ọrịa ọgụ na-emebi, karịsịa mgbe ị na-anata ọgwụgwọ redio, chemotherapy, ma ọ bụ bu nje HIV.Mycobacterium ụkwara nta nwere ike inwe nnukwu ohere ịwakpo.Ya mere, otu esi ezere ọrịa na otu esi egbochi ya nke ọma mgbe ọrịa gasịrị bụ ihe a na-elekwasị anya na mgbochi na ọgwụgwọ ụkwara nta.

Ndị otu nyocha nke Chinese Academy of Medical Sciences na Peking Union Medical College buru ụzọ jiri ụmụ oke C57BL/6 na obere ego.Mycobacterium ụkwara nta iji guzobe ụdị nnwale anụmanụ dị ka “ọrịa ụkwara nta latent” nke mmadụ, wee nyochaa nsonaazụ mgbochi ụkwara nta nke.Ganoderma lucidum.Ndị otu ahụ chọpụtara na:

Ebe ụmụ oke butere ọrịaMycobacterium ụkwara nta, a na-emeso ha n'otu ogeGanoderma lucidum nkwadebe (15 mg nke spore).s na 15 mg nke sporeegbugbere ọnụ e were ọnụ ụbọchị ọ bụla maka 16 izu, mgbe ahụ nnwale biri), ọnụ ọgụgụ nkeMycobacterium ụkwara nta na ngụgụ na splin nke ụmụ oke adịghị iche na nke a na-adịghị agwọ ọrịa.Otú ọ dị, ọ bụrụ na otu dose nkeGanoderma lucidum enwere ike inye ụmụ oke otu ọnwa tupu mmalite nke nnwale (ọrịa), ọ nwere ike belata ọnụ ọgụgụ nke ọma.Mycobacterium ụkwara nta na ngụgụ na splin nke oke.Karịsịa n'ime izu atọ na ise mbụ mgbeMycobacterium ụkwara nta na-abanye n'ime ahụ nke òké, mmetụta inhibitory dị ịrịba ama karị.

A hụkwara na nnwale ahụ na enweghị njikọ dị n'etiti ọnụ ọgụgụ nke mkpụrụ ndụ na-alụso ọrịa ọgụ na ọbara mpụta nke ụmụ oke, ọnụ ọgụgụ nke mmụba nke ụmụ oke.Mycobacterium ụkwara nta, na oke nke ngụgụ na splin ọnya.Otú ọ dị, na ụmụ oke na-eriGanoderma lucidum nkwadebe tupu ọrịa, n'ime izu atọ ma ọ bụ ise mgbe ọrịa Mycobacterium ụkwara nta butere, mkpụrụ ndụ dendritic dị n'ime ọbara na-ebelata nke ukwuu, mkpụrụ ndụ dendritic dị na ngụgụ mụbara nke ukwuu.Ihe omume a nwere ike ịkọwa ihe kpatara iri tupu nriGanoderma lucidum nwere ike igbochiMycobacterium ụkwara nta na ngụgụ ụmụ oke.

[Isi mmalite]Zhan L, et al.Iji ihe mgbochi nke Ganoderma lucidum wepụ nwere ike igbochi mmụgharị Mycobacterium ụkwara nta na ụdị òké ọhụrụ nke ọrịa ụkwara nta na-apụtaghị ìhè.Microbiol n'ihu.2016 Jenụwarị 8;6:1490 .doi: 10.3389/fmicb.2015.01490.eCollection 2015.

N'ikpeazụ

Banyere onye odee/ Oriakụ Wu Tingyao

Wu Tingyao na-akọ akụkọ mbụGanoderma lucidumozi kemgbe 1999. O bu odeeỌgwụgwọ na Ganoderma(nke e bipụtara na The People's Medical Publishing House na Eprel 2017).

★ A na-ebipụta akụkọ a n'okpuru ikike nke onye edemede ★ Ọrụ ndị a dị n'elu enweghị ike imepụtaghachi, wepụ ma ọ bụ jiri ya mee ihe n'ụzọ ndị ọzọ na-enweghị ikike nke onye edemede ★ imebi okwu a dị n'elu, onye edemede ga-agbaso ọrụ iwu metụtara ya ★ The mbụ Wu Tingyao dere ederede akụkọ a n'asụsụ Chinese ma Alfred Liu sụgharịrị ya na Bekee.Ọ bụrụ na enwere nghọtahie n'etiti ntụgharị asụsụ (Bekee) na nke izizi (Chinese), Chinese izizi ga-emeri.Ọ bụrụ na ndị na-agụ akwụkwọ nwere ajụjụ ọ bụla, biko kpọtụrụ onye edemede mbụ bụ Oriakụ Wu Tingyao.