Umphumela we-anti-tumor weI-Ganoderma lucidumbekulokhu kuyisizinda esishisayo kubacwaningi.Indlela yokusebenza kwayo iyinkimbinkimbi kakhulu, futhi imibiko yemibhalo ehlobene nayo ingaphezulu.Iningi lezazi likholelwa ukuthi i-Ganoderma lucidum polysaccharide iyisisekelo samakhemikhali esiyinhloko se-Ganoderma lucidum ukuze isebenzise imiphumela yokulwa nesimila.Umphumela we-anti-tumor we-Ganoderma lucidum polysaccharides uhlobene nesakhiwo samangqamuzana e-polysaccharides.Lapho i-molecular mass ye-polysaccharides ingaphezu kwama-daltons angu-10,000, ibonisa umthelela oqinile wokuvinjelwa kwamathumba.

I-Ganoderma lucidum polysaccharides ingayenga noma ikhuthaze i-phagocytosis yama-macrophage, ithuthukise umsebenzi wamangqamuzana abulalayo emvelo, ikhuphule izinga lokuguqulwa kwama-lymphocyte, ikhuthaze ukwakheka kwama-immunoglobulins, ithuthukise ukulawulwa kwamasosha omzimba, futhi ithuthukise ukumelana nezifo komzimba.Ngasikhathi sinye, i-Ganoderma lucidum ingaphinda ithuthukise ukubekezelelana komzimba ku-radiotherapy kanye nokwelashwa ngamakhemikhali, ukuze kuzuzwe umphumela wokulwa nesimila.I-Polysaccharide iyingxenye yodonga lwamaseli oluqinisa amangqamuzana avamile ngokumelene nama-carcinogens.Olunye ucwaningo luye lwabonisa ukuthi ama-polysaccharides nawo angavimbela ukukhululwa kwabaxhumanisi abangezwani nomzimba, ngaleyo ndlela avimbele ukuvela kokusabela okungaqondile, ngaleyo ndlela avimbele imetastasis yamangqamuzana omdlavuza ngemva kokuhlinzwa.

Umphumela ovimbelayo we-Lingzhi fruiting body extract kumdlavuza wesibindi ungama-60.34%.Ngasikhathi sinye, inganciphisa umsebenzi we-glutamic oxalacetic transaminase kanye ne-glutamic-pyruvic transaminase kuzicubu zesimila kanye ne-serum, futhi ivimbele ukwanda komugqa wamaseli womdlavuza womuntu we-TC26.Kusanda kutholakala ukuthi ukukhishwa kotshwala kwezinhlamvu ze-Ganoderma lucidum kunomphumela oqondile wokuvimbela ukukhula kwamaseli omdlavuza ku-vitro.

Inani elikhulu lokuhlolwa kwezilwane liye lakufakazela lokhoI-Reishi Mushroominomphumela we-anti-tumor, futhi indlela yayo yokulwa ne-tumor ingase ibe ngumxhumanisi, okungukuthi, ukuvimbela ukukhula kwesimila ngokuthuthukisa ukusebenza komzimba wokuzivikela.Ukuhlolwa kwamanzi ashisayo e-Ganoderma lucidum kungashukumisa i-phagocytosis ye-macrophages futhi kukhuthaze umsebenzi wesistimu ye-mononuclear-phagocytic, ukuze ama-macrophages akhiqize i-tumor necrosis factor, akhulise umsebenzi wamangqamuzana abulalayo emvelo, futhi akhuthaze ukukhiqizwa kwe-interleukin-2, ukumelana. Izidakamizwa ze-chemotherapy ukuze zenze ukuncipha kwe-leukopenia, andise ama-T cell ukuthi akhiqize i-γ-interferon, futhi athuthukise ikhono lokuphendula le-antigen-specific immune immune of T cells.Kukhona nokuhlola okuningi kokuqinisekisa ukuthi umphumela we-anti-tumor we-Ganoderma lucidum ufinyelelwa ngezinqubo zokuzivikela komzimba.