Impembelelo ye-anti-tumor yeI-Ganoderma lucidumibisoloko iyindawo eshushu kubaphandi.Indlela yokusebenza kwayo intsonkothe ​​ngakumbi, kwaye iingxelo zoncwadi ezinxulumene nazo zingaphezulu.Uninzi lwabaphengululi bakholelwa ukuba iGanoderma lucidum polysaccharide yeyona siseko semichiza yeGanoderma lucidum ukwenza iziphumo zokulwa nethumba.Impembelelo ye-anti-tumor ye-Ganoderma lucidum polysaccharides ihambelana nesakhiwo se-molecular of polysaccharides.Xa i-molecular mass ye-polysaccharides ingaphezulu kwe-10,000 daltons, ibonisa impembelelo enamandla yokuthintela kwiithumba.

I-Ganoderma lucidum polysaccharides inokukhuthaza okanye ikhuthaze i-phagocytosis ye-macrophages, iphucule umsebenzi weeseli ezibulalayo zendalo, inyuse izinga lokuguqulwa kwe-lymphocytes, ikhuthaze ukwakheka kwe-immunoglobulins, iphucule ukulawulwa kwamajoni omzimba, kwaye iphucule ukuxhathisa kwezifo zomzimba.Kwangaxeshanye, iGanoderma lucidum inokonyusa unyamezelo lomzimba kwiradiotherapy kunye nechemotherapy, ukuze kuphunyezwe isiphumo sokulwa nethumba.I-Polysaccharide yinxalenye yodonga lweeseli ezomeleza iiseli eziqhelekileyo ezichasene ne-carcinogens.Olunye uphononongo lubonise ukuba i-polysaccharides inokunqanda ukukhutshwa kwabalamli abangevaniyo, ngaloo ndlela ivalela ukwenzeka kokungachanekiyo, oko kuthintele imetastasis yeeseli zomhlaza emva kotyando.

Impembelelo yokuthintela i-Lingzhi fruiting body extract kumhlaza wesibindi yi-60.34%.Kwangaxeshanye, inokunciphisa umsebenzi we-glutamic oxalacetic transaminase kunye ne-glutamic-pyruvic transaminase kwi-tumor tissue kunye ne-serum, kwaye inqande ukwanda komgca weseli yomhlaza womntu TC26.Kutshanje kuye kwafunyaniswa ukuba isicatshulwa sotywala seGanoderma lucidum spores sinefuthe elithintela ngokuthe ngqo ukukhula kweeseli zomhlaza kwi-vitro.

Uvavanyo oluninzi lwezilwanyana luye lwakungqina okoReishi Mushroomine-anti-tumor effect, kwaye indlela yayo yokuchasana ne-tumor inokuba yi-host-mediated, oko kukuthi, inqanda ukukhula kwethumba ngokuphucula ukusebenza komzimba.Uvavanyo lwe-Ganoderma lucidum lucidum lwesicatshulwa lwamanzi ashushu lunokuvuselela i-phagocytosis ye-macrophages kwaye lukhuthaze umsebenzi wenkqubo ye-mononuclear-phagocytic, ukuze i-macrophages ivelise i-tumor necrosis factor, yandise umsebenzi weeseli zokubulala zendalo, kwaye ikhuthaze ukuveliswa kwe-interleukin-2, ukuxhathisa. amayeza echemotherapy ukukhuthaza ukuncipha kweleukopenia, ukwandisa iiseli ze-T ukuvelisa i-γ-interferon, kunye nokuphucula amandla okuphendula amajoni omzimba athile kwiiseli ze-T.Kukho neemvavanyo ezininzi zokuqinisekisa ukuba i-anti-tumor effect ye-Ganoderma lucidum iphunyezwa ngeendlela zokugonywa kwe-immunoregulatory.