Septhemba 1, 2015 / Isikhungo sikaMaratha Mandal sikaNathajirao G. Halgekar seDental Sciences and Research Cente / Contemporary Clinical Dentistry

Umbhalo/Wu Tingyao

Ngikuzwile lokho kufakwa isiceloI-Ganoderma lucidumimpushana ngqo ezinsinini ezivuvukele ingadambisa ukuvuvukala kwe-periodontal nobuhlungu.Abantu abathanda ukusebenzisaI-Ganoderma lucidumkungase kuthathe kalula lokhu “kukhuluma ngomlomo”, kodwa kulabo abangajwayelene nakhoI-Ganoderma lucidum, kungase kufane nephupho.Isayensi ingaluhlola kanjani lolu daba?Uma sibheka umbiko oshicilelwe ku-“Contemporary Clinical Dentistry” ngososayensi baseNdiya ngoSepthemba 2015, ikhambi elibonakala liyisintu alinangqondo.

Ibhaktheriya ye-Anaerobic Gram-negative ingalimaza izicubu zezinsini futhi ibangele i-periodontitis engapheli.Leli qembu lamagciwane ngokuvamile lingena emlonyeni nokudla futhi lihlale endaweni ephakathi kwamazinyo nezinsini.Uma zingasuswa ngesikhathi, zizozala lapha, okungeke kubangele i-periodontitis kuphela kodwa futhi kubangele umoya omubi, futhi kwenze amazinyo aphume ezinsinini ezixegayo.Ngakho-ke, nakuba amabhaktheriya emancane, azoba nomthelela omkhulu enjabulweni yokudla kwabantu kanye nobudlelwano phakathi kwabantu.

I-Prevotella intermedia iyona ebaluleke kakhulu kuleli qembu lamagciwane.Abacwaningi bawahlukanisa nama-plaque amazinyo eziguli ezingama-20 ezinezifo ezingamahlalakhona ze-periodontal.Ngemuva kokwelashwa, isixazululo se-spore powder aqueous (10 mg we-spore powder ku-1 mL ye-saline evamile) yakhuliswa ngamagciwane avela ezigulini ezahlukene amahora angu-48 ~ 72.

Kwatholakala ukuthi phakathi kwamasampula ebhaktheriya angama-20, amasampula ebhaktheriya ayi-13 ayezwela ekugxiliseni okuningi (1 ~ 500 mcg/mL)I-Ganoderma lucidumisixazululo se-spore aqueous (esinomphumela we-bacteriostatic), kodwa amasampula ebhaktheriya ayi-7 ahlala engathinteki kungakhathaliseki ukuthi yikuphi ukugcwalaI-Ganoderma lucidumspore isixazululo aqueous kuyinto.Ngokwesilinganiso, ukuhlushwa okuphansi kakhuluI-Ganoderma lucidumizinhlamvu ezivimbela ukukhulaI-Prevotella intermediakwakungu-3.62 mcg/mL.

Nakuba umphumela ungewona u-100%, kukhona okungenani amathuba angama-65% okuthi ukusetshenziswa kwangaphandle kwawoI-Ganoderma lucidumi-spore powder ingathuthukisa ukuvuvukala kwe-periodontal.Abacwaningi bakholelwa ukuthi imiphumela yalokhu kuhlola inikeza ubufakazi besayensi ngokubaluleka kweI-Ganoderma lucidumizinhlamvu ezisetshenziswa ngaphandle ezinsinini ezivuthayo;uma iI-Ganoderma lucidumI-spore powder ingathathwa ngomlomo ngesikhathi esifanayo, ithuthukise ukuqina komzimba weziguli ezinemiphumela yokuzivikela komzimba.I-Ganoderma lucidumngokwayo ingase ibe usizo kakhulu ekwelapheni isifo se-periodontal.

Yiqiniso, gcina umsebenzi oyisisekelo wokuvimbela nokwelapha isifo se-periodontal, okuhlanganisa ukuxubha ngesixubho, ukuxubha, nokugeza amazinyo njalo ukuze uvimbele amagciwane angalimazi izinsini, okungenzeka kube umkhuba wangempela oyisisekelo.

[Idatha] Nayak RN, et al.Ukuhlolwa komsebenzi we-anti-microbial we-spore powder ye-Ganoderma lucidum kuma-isolates emitholampilo ye-Prevotella intermedia: Ucwaningo lomshayeli.Contemp Clin Dent.2015 Sep;6(Suppl 1):S248-S252.

PHELA

 
Mayelana nombhali/ Nks. Wu Tingyao

UWu Tingyao ubelokhu ebika ngolwazi lukaLingzhi kusukela ngo-1999. Ungumbhali wencwadiUkwelapha nge-Ganoderma(ishicilelwe ku-People's Medical Publishing House ngo-Ephreli 2017).
 
★ Lesi sihloko sishicilelwe ngaphansi kokugunyazwa okukhethekile kombhali.★ Le misebenzi engenhla ayinakuphinda ikhiqizwe, ikhishwe noma isetshenziswe ngezinye izindlela ngaphandle kwemvume yombhali.★ Ukwephulwa kwesitatimende esingenhla, umbhali uzophishekela izibopho zayo ezingokomthetho ezihlobene.★ Umbhalo wokuqala walesi sihloko ubhalwe ngesiShayina nguWu Tingyao futhi wahunyushelwa esiNgisini ngu-Alfred Liu.Uma kukhona ukungqubuzana phakathi kokuhumusha (isiNgisi) kanye nokwangempela (isiShayina), isiShayina sangempela siyonqoba.Uma abafundi benemibuzo, sicela uthinte umbhali wokuqala, uNksz. Wu Tingyao.