Tus kab mob coronavirus tshiab tau ua phem rau tib neeg tau peb xyoos txog tam sim no.Txij li thaum lub Kaum Ob Hlis 2022, kev kuaj nucleic acid ib txwm raug tshem tawm hauv ntau qhov chaw thoob plaws Suav teb, thiab daim ntawv pov thawj nucleic acid tsis zoo rau COVID-19 yuav tsis raug kuaj ntxiv lawm.Tuam Tshoj tau nkag mus rau lub sijhawm ntawm kev sib koom ua ke nrog kev sib kis.Tau ntsib tus kab mob siab tshaj plaws, yuav ua li cas txhawm rau txhim kho kev tiv thaiv thiab ua thawj tus neeg saib xyuas koj tus kheej kev noj qab haus huv tau dhau los ua lub ntsiab lus ntawm kev txhawj xeeb tshaj plaws rau tag nrho lub zej zog.

Raws li qhov zoo ntawm cov tshuaj suav tshuaj hauv kev tiv thaiv thiab tswj kev sib kis tau dhau los ua qhov tseem ceeb, "Ganoderma lucidum", uas muaj cov txiaj ntsig ntawm kev txhim kho kev tiv thaiv thiab tswj kev sib npaug ntawm kev ua haujlwm tag nrho, tau ua tau zoo tshaj plaws hauv kev tiv thaiv thiab tswj kev sib kis.

Yog li, uaGanoderma lucidumPuas muaj kev cuam tshuam rau tus kabmob tshiab tshiab?Cov neeg mob COVID-19 tuaj yeem noj tauGanoderma lucidumkom muaj txiaj ntsig zoo rau lub cev?Ntau qhov kev tshawb fawb tsis ntev los no muab pov thawj zoo rau peb.

Thaum lub Plaub Hlis 2020, phau ntawv xov xwm kev kawm thoob ntiaj tebMoleculesluam tawm "Natural Bioactive Compounds los ntawm Fungi ua Cov Neeg Sib Tw Muaj Peev Xwm rau Protease Inhibitors thiab Immunomodulators Thov rau Coronaviruses".

Daim ntawv no tshuaj xyuas qhov kev tshawb pom thiab kev tshawb fawb txog kev ua tau zoo ntawm cov tshuaj nquag ntawm cov fungi hauv inhibiting human immunodeficiency virus (HIV) protease.Nws tawm tswv yim tias active compounds ntawm fungi, tshwj xeeb tshaj yogGanoderma lucidum(triterpenoids, polysaccharides thiab me me molecular proteins) ua lub luag haujlwm tseem ceeb hauv inhibiting human immunodeficiency viral (HIV) protease.

Txoj kev tshawb no muab cov neeg siv tshuaj muaj peev xwm rau kev tiv thaiv thiab kho tus mob coronaviruses, uas tuaj yeem siv yav tom ntej los tiv thaiv thiab kho tus mob coronaviruses, tshwj xeeb tshaj yog rau kev tiv thaiv thiab kho cov kab mob tshiab tshiab.

Hauv 2021, "Kev Ua Haujlwm ntawm National Academy of Sciences (PNAS) 2021 Vol.118 No.5 ″ tau luam tawm ib tsab xov xwm “Kev Qhia Txog Cov Tshuaj Tiv Thaiv Kab Mob Kab Mob Tshiab los ntawm Cov Tshuaj thiab Tshuaj Kho Mob”.Txoj kev tshawb nrhiav pom tiasGanoderma lucidumdej extract tuaj yeem cuam tshuam kev kis tus kabmob tshiab (SARS-Cov-2) ob leeg hauv vivo thiab hauv vitro.

Suav tshuaj ntsuab dej extract (1.0 g / 20 mL, 5%) thiabGanoderma lucidumpolysaccharide RF3 (0.25 mg / mL, 0.025%).IC50 = ib nrab inhibitory (tus kab mob) koob tshuaj;CC50 = ib nrab koob tshuaj lom

Cov txiaj ntsig ua pov thawj tiasGanoderma lucidumpolysaccharide RF3 (2μg / ml) muaj cov tshuaj tua kab mob tseem ceeb ntawm SARS-Cov-2 kab lis kev cai hauv vitro, thiab nws tseem muaj cov haujlwm inhibitory thaum diluted rau 1280 zaug.Tab sis nws tsis muaj toxicity rau tus kab mob host Vero E6 hlwb.

(A) Cov kws tshawb fawb tau pom cov tshuaj tiv thaiv-sars-cov-2 cov teebmeem ntawm cov tshuaj thiab cov tshuaj rho tawm hauv hamsters.Hnub 0, hamsters tau kis los ntawm intranasal instillation ntawm SARS-CoV-2.Tom qab ntawd, cov hamsters tau noj cov tshuaj hauv qhov ncauj (30mg / kg / d) thiab cov tshuaj suav tshuaj suav tshuaj (200mg / kg / d), ob zaug / d, thiab cov kab mob hauv lub ntsws ntawm cov hamsters tau ntsuas tom qab 3 hnub ( n = 5), * P < 0.05 ;* * P < 0.005(B) Lub cev hnyav hloov tom qab 3-d kev kho mob, N = 5 hauv pawg xeem, N = 6 hauv pawg tswj.Cov txiaj ntsig tau ua pov thawj tias piv nrog pawg tswj hwm kab mob, kev tswj hwm qhov ncauj ntawmGanoderma lucidumpolysaccharide RF3 tuaj yeem txo cov kab mob hnyav (cov ntsiab lus) hauv lub ntsws ntawm cov hamsters kis tus kab mob SARS-Cov-2, thiab cov tsiaj tsis poob qhov hnyav thaum kuaj.Hauv vivo thiab hauv vitro tshuaj tiv thaiv kab mob ua pov thawj tiasGanoderma lucidumpolysaccharide RF3 cuam tshuam rau tus kab mob SARS-Cov-2.

Thaum Lub Ob Hlis 2020, Xib Fwb Sun Guifan, tus lwm thawj ntawm Precision Nutrition Professional Committee ntawm Tuam Tshoj Nutrition thiab Health Food Association, thiab lub koom haum tiv thaiv tshuaj ntawm Tuam Tshoj Medical University, tshaj tawm tsab xov xwm "Qhov thib ob nrov science series kab lus ntawm kev pab meej. nyob rau hauv kev tiv thaiv thiab kho tus kab mob tshiab coronavirus hais txog kev noj zaub mov - kev ua haujlwm ntawm cov khoom noj khoom haus ", tshaj tawm rau pej xeem 12 yam khoom noj khoom haus uas tuaj yeem pab tiv thaiv thiab kho tus kabmob tshiab, suav nrogGanoderma lucidum, ib txwm suav tshuaj ntsuab!

Hauv tsab xov xwm, Xib Fwb Sun tau qhia meej meej tiasGanoderma lucidummuaj cov tshuaj tiv thaiv kab mob, uas tuaj yeem cuam tshuam ncaj qha rau nws lub peev xwm tiv thaiv kab mob thiab kis kab mob.Cov kev tshawb fawb ntawm tes tau pom tias Reishi extract tuaj yeem nres lossis qeeb kev loj hlob ntawm tus kab mob khaub thuas, HIV, kab mob siab B thiab ntau lwm yam kab mob, thim rov qab hnub nyoog txog kev poob qis hauv lub cev tsis muaj zog.

Xib fwb Zhi-Bin Lin ntawm Peking University Health Science Center, uas tau tsom mus rau kev tshawb fawb pharmacological ntawmGanoderma lucidumrau ntau tshaj 50 xyoo, qhia txog cov nyhuv antiviral thiab mechanism ntawmGanoderma lucidumnyob rau hauv tsab xov xwm "Antiviral nyhuv ntawmGanoderma lucidum” luam tawm thaum kawg ntawm 2020, taw qhia qhov ntawdGanoderma lucidum, tshwj xeeb tshaj yog cov triterpenes muaj nyob rau hauvGanoderma lucidum, muaj inhibitory cuam tshuam rau ntau yam kab mob.

Xib fwb Zhi-Bin Lin ua ntej txheeb xyuas cov txheej txheem ntawm cov tshuaj tiv thaiv kab mob ntawmGanoderma lucidum, uas cuam tshuam nrog inhibiting adsorption lossis nkag mus ntawm cov kab mob mus rau cov hlwb, inhibiting kab mob uncoating, inhibiting kev ua ntawm enzymes (xws li thim rov qab transcriptase thiab protease) xav tau rau cov kab mob synthesis hauv hlwb, thiab cuam tshuam cov kab mob DNA lossis RNA replication tab sisGanoderma lucidumtsis muaj toxicity rau host cells thiab muaj kev sib koom ua ke nrog cov tshuaj tiv thaiv kab mob paub.

Tsab ntawv kuj tau taw qhia tias qhov kev kho mob ua tau zoo ntawmGanoderma lucidumntawm cov kab mob viral tej zaum yuav muaj feem cuam tshuam nrog kev tiv thaiv kab mob ntawm cov kab mobGanoderma lucidum, anti-oxidation thiab dawb radical scavenging nyhuv ntawmGanoderma lucidum, thiab kev tiv thaiv zoo ntawmGanoderma lucidumntawm lub cev thiab cov ntaub so ntswg.

Kev tshawb fawb niaj hnub qhia tiasGanoderma lucidumyog nplua nuj nyob rau hauv kaum ob ntawm cov khoom xyaw nquag, uas yog "tus neeg xa xov liaison" txhawm rau txhim kho kev tiv thaiv.

Feem ntau hais lus, qhov siab dua cov ntsiab lus ntawm cov khoom xyaw nquag, cov txiaj ntsig zoo ntawm kev txhim kho kev tiv thaiv.

Raws li thaum ntxov xyoo 2017, GanoHerb thiab Fujian Provincial Chaw Tswj Xyuas Kab Mob thiab Tiv Thaiv tau sib koom ua haujlwm tshawb fawb txog "Cov nyhuv ntawmGanoderma LucidumGranules ntawm Immune Function ”.Cov nas tau muab faib ua tsib pawg, thiab lawv tau muab cov tshuaj sib txawvGanoderma lucidumgranules (los ntawm GanoHerb Technology (Fujian) Corporation).

Los ntawm kev sib piv txhua pawg koob tshuaj ntawm cov qauv nrog rau pawg tswj hwm, nws tau pom tias: ①Cov kab mob ntshav qab zib siab tau ua kom muaj peev xwm loj hlob ntawm nas spleen lymphocytes induced los ntawm ConA thiab ncua-hom hypersensitivity ntawm nas induced los ntawm DNFB;② Cov pab pawg nruab nrab thiab cov koob tshuaj siab tau ua kom muaj peev xwm ua kom muaj peev xwm tiv thaiv kab mob, pab pawg neeg koob tshuaj tau nce qib ntawm cov ntshav hemolysin hauv cov nas;③ Cov pab pawg neeg siv koob tshuaj ntau tau txhim kho cov haujlwm ntawm NK hlwb hauv cov nas.

Qhov xaus kos los ntawm kev xeem yog Ganoderma granules formulated nrogGanoderma lucidumextract thiabGanoderma sinenseextract muaj cov haujlwm ntawm kev txhim kho kev tiv thaiv.Raws li lub tuam txhab ua lag luam tsom mus rau Ganoderma kev lag luam kev noj qab haus huv, txij li thaum muaj tus kab mob sib kis xyoo 2020, GanoHerb tau pub nyiaj tag nrho ntawm 9.126 lab yuan hauv cov nyiaj ntsuab thiab cov ntaub ntawv suav nrog.Ganoderma lucidumspore yog ',Ganoderma lucidumspore hmoov thiabGanoderma lucidumrho tawm los pab cov neeg ua haujlwm kho mob pem hauv ntej thiab lwm tus neeg ua haujlwm txhim kho lawv tus kheej kev tiv thaiv thiab tsim kom muaj kev tiv thaiv kab mob ua ke.Nws yog qhov tseeb vim yog lub luag haujlwm no thiab kev cog lus los tawm tsam kev sib kis uas nyob rau xyoo 2021, GanoHerb Technology (Fujian) Corporation., ib lub koom haum ntawm GanoHerb Group, tau txais txiaj ntsig ntawm "Fujian Xeev Advanced Private Enterprise hauv Kev Tawm Tsam Tawm Tsam Novel Coronary Pneumonia Sib kis mus".

Ib lub sijhawm ntawm kev sib tw rau kev tiv thaiv kab mob tau los.Koj puas tau khaws cia ntawm GanoHerb organicGanodermauas txhawb kev tiv thaiv thiab tswj kev loj hlob?