Mliri watsopano wa coronavirus wasakaza anthu kwa zaka zitatu mpaka pano.Kuyambira Disembala 2022, kuyezetsa kwa nucleic acid kokhazikika kwaletsedwa m'malo ambiri ku China, ndipo satifiketi yoyeserera ya nucleic acid ya COVID-19 sidzayang'aniridwanso.China yalowa m'nthawi yogwirizana ndi mliriwu.Poyang'anizana ndi chiwopsezo chotheka cha matenda, momwe mungakulitsire chitetezo chokwanira ndikukhala munthu woyamba kukhala ndi udindo paumoyo wanu wakhala mutu wodetsa nkhawa kwambiri kwa anthu onse.

Ubwino wamankhwala achi China popewa komanso kuwongolera mliri wakula kwambiri, "Ganoderma lucidum", zomwe zimapangitsa kuti chitetezo cha mthupi chitetezeke komanso kusunga bwino ntchito zonse, zachita bwino kwambiri popewera ndi kuwongolera mliriwu.

Kotero, zimateroGanoderma lucidumali ndi choletsa chilichonse pa coronavirus yatsopano?Kodi odwala omwe ali ndi COVID-19 angadyeGanoderma lucidumkukhala ndi zotsatira zabwino pa thupi?Zotsatira zingapo zaposachedwa zimatipatsa umboni wabwino.

Mu Epulo 2020, magazini yapadziko lonse lapansi yamaphunziroMamolekyuadasindikiza "Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses".

Pepalali likuwunikiranso za kupezeka ndi kupita patsogolo kwa kafukufuku wa zinthu zachilengedwe zogwira ntchito za bowa zomwe zimalepheretsa kachilombo ka HIV (HIV) protease.Akuti yogwira mankhwala bowa, makamakaGanoderma lucidum(triterpenoids, polysaccharides ndi mapuloteni ang'onoang'ono a molekyulu) amagwira ntchito yofunika kwambiri poletsa chitetezo cha mthupi cha munthu kukhala ndi kachilombo ka HIV (HIV).

Kafukufukuyu akupereka munthu yemwe angathe kukhala ndi mankhwala oletsa komanso kuchiza ma coronavirus, omwe angagwiritsidwe ntchito mtsogolo popewa ndikuchiza ma coronavirus, makamaka popewa komanso kuchiza matenda atsopano a coronavirus.

Mu 2021, "Proceedings of the National Academy of Sciences (PNAS) 2021 Vol.118 No.5 ″ idasindikiza nkhani yakuti "Kuzindikiritsa Zoletsa za Novel Coronavirus Infection from Listed Drugs and Herbal Medicines".Kafukufukuyu anapeza kutiGanoderma lucidumKutulutsa kwamadzi kumatha kuletsa kwambiri matenda a coronavirus (SARS-Cov-2) mu vivo komanso mu vitro.

Chinese mankhwala azitsamba madzi Tingafinye (1.0 g/20 mL, 5%) ndiGanoderma lucidumpolysaccharide RF3 (0.25 mg/mL, 0.025%).IC50=mulingo woletsa theka (kachilombo);CC50=theka lapoizoni

Zotsatira zikutsimikizira zimenezoGanoderma lucidumpolysaccharide RF3 (2μg/ml) imakhala ndi mphamvu yoletsa ma virus pa SARS-Cov-2 yokulitsidwa mu m'galasi, ndipo imakhalabe ndi ntchito yolepheretsa ikachepetsedwa mpaka 1280.Koma ilibe kawopsedwe kwa ma cell a Vero E6 omwe ali ndi kachilomboka.

(A) Ofufuza adawona zotsatira za anti-sars-cov-2 zamankhwala ndi zowonjezera mu hamsters.Patsiku la 0, ma hamster adayatsidwa ndi intranasal instillation ya SARS-CoV-2.Pambuyo pake, ma hamster adaperekedwa pakamwa mankhwalawa (30mg/kg/d) ndi mankhwala achi China (200mg/kg/d), kawiri/d, ndipo kuchuluka kwa ma virus m'mapapo a hamsters adayesedwa patatha masiku atatu ( n = 5), * P <0.05 ;* * P <0.005(B) Kusintha kwa thupi pambuyo pa chithandizo cha 3-d, N = 5 mu gulu loyesera, N = 6 mu gulu lolamulira.Zotsatira zatsimikizira kuti poyerekeza ndi gulu loletsa matenda, kasamalidwe ka pakamwa kaGanoderma lucidumpolysaccharide RF3 akhoza kwambiri kuchepetsa kuchuluka kwa mavairasi (zokhutira) m'mapapo a hamsters omwe ali ndi kachilombo ka SARS-Cov-2, ndipo nyama sizinawonde poyesa.Kuyesa kwa ma antiviral mu vivo ndi in vitro kunatsimikizira iziGanoderma lucidumpolysaccharide RF3 yoletsa kwambiri matenda a SARS-Cov-2.

Mu February 2020, Pulofesa Sun Guifan, wachiwiri kwa wapampando wa Precision Nutrition Professional Committee ya China Nutrition and Health Food Association, ndi Institute of Preventive Medicine ya China Medical University, adatulutsa poyera nkhani yakuti "Nkhani yachiwiri yotchuka ya sayansi yofotokoza za thandizo lenileni. popewa komanso kuchiza matenda atsopano a coronavirus pankhani yazakudya - ntchito yazakudya zopatsa thanzi", adalengeza kwa anthu mitundu 12 yazakudya zomwe zingathandize kupewa ndi kuchiza matenda atsopano a coronavirus, kuphatikizaGanoderma lucidum, mankhwala azitsamba achi China!

M’nkhaniyo, Pulofesa Sun anafotokoza momveka bwino kutiGanoderma lucidumali ndi chitetezo chamthupi cholimbikitsa, chomwe chingakhudze mwachindunji mphamvu yake yolimbana ndi matenda a bakiteriya ndi ma virus.Kafukufuku wama cell a labotale awonetsa kuti kuchotsa kwa Reishi kumatha kuyimitsa kapena kuchedwetsa kukula kwa kachilombo ka fuluwenza, HIV, hepatitis B ndi ma virus ena ambiri, kubweza kuchepa kwa ukalamba kwa chitetezo chamthupi.

Pulofesa Zhi-Bin Lin wa ku Peking University Health Science Center, yemwe adayang'ana kwambiri kafukufuku wamankhwala aGanoderma lucidumkwa zaka zoposa 50, anayambitsa sapha mavairasi oyambitsa zotsatira ndi limagwirira waGanoderma lucidumm’nkhani yakuti “Matenda Olimbana ndi Matenda aGanoderma lucidum” lofalitsidwa kumapeto kwa 2020, ndikuwonetsa iziGanoderma lucidum, makamaka ma triterpenes omwe ali muGanoderma lucidum, amalepheretsa ma virus osiyanasiyana.

Pulofesa Zhi-Bin Lin poyamba adasanthula njira ya antiviral effectGanoderma lucidum, zomwe zimaphatikizapo kuletsa kulowetsedwa kapena kulowa kwa mavairasi m'maselo, kulepheretsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda zitheke.Ganoderma lucidumalibe kawopsedwe ku khamu maselo ndipo ali synergistic kwenikweni osakaniza odziwika sapha mavairasi oyambitsa mankhwala.

Nkhaniyi inanenanso kuti chipatala champhamvu chaGanoderma lucidumpa tizilombo matenda mwina makamaka zokhudzana ndi chitetezo cha m'thupi lamulo laGanoderma lucidum, anti-oxidation ndi free radical scavening zotsatira zaGanoderma lucidum, ndi chitetezo chaGanoderma lucidumpa ziwalo ndi minofu.

Kafukufuku wamakono amasonyeza zimenezoGanoderma lucidumali ndi zinthu zambiri zogwira ntchito, zomwe ndi "messenger" wowonjezera chitetezo chokwanira.

Nthawi zambiri, kuchuluka kwa zosakaniza zogwira ntchito kumapangitsa kuti chitetezo cha mthupi chitetezeke bwino.

Kumayambiriro kwa chaka cha 2017, GanoHerb ndi Fujian Provincial Center for Disease Control and Prevention pamodzi anayambitsa ntchito yofufuza za "Zotsatira zaGanoderma LucidumGranules pa Ntchito ya Immune".Makoswe anagawidwa m’magulu asanu, ndipo anapatsidwa milingo yosiyanasiyana yaGanoderma lucidumgranules (wolemba GanoHerb Technology (Fujian) Corporation).

Poyerekeza gulu la mlingo uliwonse wa chitsanzo ndi gulu lolamulira, zinapezeka kuti: ① Gulu lachitsanzo la mlingo waukulu linalimbikitsa kwambiri kuchulukitsidwa kwa ma lymphocyte a mbewa omwe amapangidwa ndi ConA ndi kuchedwa kwamtundu wa hypersensitivity wa mbewa wopangidwa ndi DNFB;②Magulu apakati ndi apamwamba kwambiri adakulitsa luso la kubadwa kwa ma antibody, gulu lapamwamba kwambiri lidawonjezera kuchuluka kwa seramu hemolysin mu mbewa;③Gulu lachitsanzo la mlingo waukulu linalimbikitsa kwambiri ntchito za maselo a NK mu mbewa.

Mapeto omwe adachokera ku mayesowa ndikuti ma Ganoderma granules opangidwa ndiGanoderma lucidumkuchotsa ndiGanoderma sinenseChotsitsacho chimakhala ndi ntchito yowonjezera chitetezo chokwanira.Monga kampani yotsogola yomwe ikuyang'ana kwambiri zamakampani azaumoyo a Ganoderma, kuyambira pomwe mliriwu udayamba mu 2020, GanoHerb yapereka ndalama zokwana 9.126 miliyoni za yuan ndi zida kuphatikiza.Ganoderma lucidummafuta a mpendadzuwa,Ganoderma lucidumspore powder ndiGanoderma lucidumchothandizira othandizira azachipatala akutsogolo ndi ena ogwira nawo ntchito kukonza chitetezo chawo komanso kupanga chitetezo chokwanira pamodzi.Ndi chifukwa cha udindo komanso kudzipereka kumeneku kuyesetsa kulimbana ndi mliriwu kuti mu 2021, GanoHerb Technology (Fujian) Corporation., wothandizidwa ndi GanoHerb Group, adalandira "Fujian Province Advanced Private Enterprise polimbana ndi Novel Coronary Pneumonia. Mliri".

Nthawi ya mpikisano woteteza chitetezo cha mthupi yafika.Kodi mwasungirako GanoHerb organicGanodermazomwe zimalimbitsa chitetezo chamthupi ndikuwongolera nyonga?