Wu Tingyao

Kungakhathaliseki ukuthi isetshenziswa yodwa noma ihlangene, i-Lingzhi (ebuye ibizwe ngokuthi i-Ganoderma lucidum noma i-Reishi) inemiphumela yokulawula umfutho wegazi, ukwehlisa izimpawu ezibonisa ukuthi uzizwa ukhululekile futhi uthuthukise i-lipids yegazi.Ngaphezu kwalokho, ukusetshenziswa isikhathi eside kwe-Lingzhi ngeke kubangele imiphumela emibi emisebenzini yomzimba.Ukuze uthole imininingwane, bheka "Ukuhlolwa komtholampilo eminyakeni engu-50 edlule kuqinisekisile ukuthi i-Lingzhi ingathuthukisa umfutho wegazi ophakeme" futhi "Ucwaningo lwasemtholampilo luqinisekisile ukuthi i-Lingzhi ithuthukisa umfutho wegazi ophakeme kodwa ayithinti umfutho wegazi ojwayelekile".

Kodwa-ke, i-Lingzhi ayinazo kuphela izinzuzo ezingenhla zomfutho wegazi ophakeme kodwa futhi ithuthukisa i-viscosity yegazi, i-microcirculation (ukujikeleza kwegazi kwama-capillaries), ushukela wegazi kanye nokumelana ne-insulin ezigulini ezinomfutho wegazi ophakeme.Ngisho nangaphandle kokuthinta umfutho wegazi, kungakhuthaza i-microcirculation futhi kwandise ukugcwala kwegazi kubantu abanempilo.

I-Lingzhi ithuthukisa umfutho wegazi ezigulini ezinomfutho wegazi ophakeme ezine-viscosity ephezulu yegazi.

Ngo-1992, i-Shanghai Medical University kanye ne-Wakan Shoyaku Laboratory Co ngokuhlanganyela bashicilela umbiko womtholampilo “kuJournal of Chinese Pharmaceutical Sciences”, owawuhlaziya izinzuzo zokudla i-Lingzhi ezigulini ezinezifo zombili zenhliziyo nemithambo yegazi kanye ne-viscosity ephezulu yegazi.Ingqikithi yezifundo ezingama-33 (ezineminyaka engama-45 kuye kwengama-86 ubudala) zahlolwa, futhi eziyi-17 kuzo zazinomfutho wegazi ophakeme.

Bathathe amaphilisi ama-2 e-Lingzhi (aqukethe u-110 mg we-Lingzhi fruiting body extract, okulingana no-2.75 g we-Lingzhi fruiting body) ngosuku.Ngemva kwamaviki ama-2, ngaphezu kwengxenye yezifundo zathuthukisa izimpawu zazo ezifana nekhanda elibuhlungu, ukucwayiza, ukuba ndikindiki kwemilenze, ukuqina kwesifuba nokuqwasha;kubantu abanomfutho wegazi ophakeme, umfutho wegazi we-systolic ne-diastolic wehle ngo-12.5 mmHg (8.5%) no-6.4 mmHg (7.2%), ngokulandelana, umehluko ophawulekayo wezibalo uma kuqhathaniswa nangaphambi kokuhlolwa (Umfanekiso 1).

Umfutho wegazi ungathinteka ngokushaya kwenhliziyo (inani lezikhathi inhliziyo eshaya ngalo ngomzuzu lapho uphumule) futhi kuhlotshaniswa kahle nokubonakala kwegazi (ukungaguquguquki kwegazi).

Njengoba zonke izifundo (kuhlanganise nalabo abanomfutho wegazi ovamile) zazingenawo umehluko omkhulu ekushayeni kwenhliziyo ngaphambi nangemva kokuhlolwa (izikhathi ezingu-74 → izikhathi ezingu-77), zonke zazisebangeni elivamile, kodwa i-viscosity yegazi yancipha kakhulu.Ngakho-ke, kucatshangelwa ukuthi isizathu esenza uLingzhi ehlise umfutho wegazi ophakeme singase sihlobane nokuthuthukiswa kwe-viscosity yegazi.

I-Lingzhi ithuthukisa okunzima ukuwelapha umfutho wegazi ophakeme futhi ithuthukisa i-viscosity yegazi kanye ne-microcirculation.

Ukuqinisekisa ukuthi kukhona ubudlelwano phakathi kokuthuthukiswa komfutho wegazi ophakeme ngu-Lingzhi kanye nokuthuthukiswa kwe-viscosity yegazi, ithimba lase-Shanghai Medical University kanye ne-Wakan Shoyaku Laboratory Co, ngokubambisana neSibhedlela Sesine Sabantu sase-Xuzhou City, basebenzise okufanayo. Amalungiselelo e-Lingzhi njengakulolu cwaningo olungenhla ukwenza ukuhlolwa okungahleliwe (okuqoqiwe), okuyizimpumputhe kabili (kokubili abaphenyi kanye nezifundo babengazi ukuthi yiliphi iqembu izihloko ezabelwe kulo) kanye nokuhlolwa komtholampilo okulawulwa yi-placebo ezigulini ezine-hypertension ye-refractory.

Ngokusho kwephepha lomcwaningi elanyatheliswa ku- "Journal of Chinese Microcirculation" ngo-1999, "iziguli ezinomfutho wegazi ophakeme" ezazibambe iqhaza ekuhlolweni komtholampilo zazihlanganisa iziguli ezine-hypertension ebalulekile ezathola ukwelashwa kwe-captopril (i-angiotensin converting enzyme inhibitor) noma i-nimodipine (i-calcium antagonist). ) isikhathi esingaphezu kwenyanga eyodwa kodwa umfutho wegazi wabo usangaphezu kuka-140/90 mmHg.

Isilinganiso seminyaka yezifundo sasiyiminyaka engu-57.8 ± 9.6, futhi isilinganiso sowesilisa nowesifazane sasicishe sibe ngu-2:1.Ngesikhathi kuhlolwa, iziguli eziqale zathatha imithi yasentshonalanga zathatha imithi yasentshonalanga njengenjwayelo.Iqembu le-placebo (amacala angu-13) athatha i-placebo nsuku zonke kuyilapho iqembu le-Lingzhi (amacala angu-27) lithatha amaphilisi e-Lingzhi angu-6 nsuku zonke (aqukethe 330 mg Lingzhi fruiting body extract), okulingana no-8.25 g we-Lingzhi fruiting body;lesi sithako siphindwe izikhathi ezi-3 kunokuhlolwa komtholampilo okukhulunywe ngakho ngenhla okushicilelwe ngo-1992).

(1) Ukuthuthuka okuphelele komfutho wegazi
Ngemuva kwezinyanga ezi-3 zokuhlolwa, umfutho wegazi weqembu le-Lingzhi, noma ngabe umfutho wegazi we-aortic (ukulinganisa ingalo), umfutho wegazi we-arteriolar (ukulinganisa umunwe) noma umfutho wegazi we-capillary (ukulinganisa ukugoqa kwezinzipho-ukugoqa kwesikhumba omngceleni ophansi unqenqema lwezinzipho nokuvala impande yezipikili) bekuphansi kakhulu kunangaphambi kokuhlolwa, kodwa alukho ushintsho olubalulekile eqenjini le-placebo (Umfanekiso 2).

(2)I-viscosity yegazi nayo yehla
Ngasikhathi sinye, izinkomba eziyinhloko zokuhlola i-viscosity yegazi, kufaka phakathi izinga eliphezulu le-shear (isivinini sokugeleza kwegazi okusheshayo) i-viscosity yegazi lonke, izinga eliphansi le-shear (ijubane lokugeleza kwegazi eliphansi) lonke i-viscosity yegazi kanye ne-plasma viscosity ethinta i-viscosity yegazi (igazi i-viscosity ngemva kokususwa kwamangqamuzana egazi, athintwa okuqukethwe kwamaprotheni, amafutha kanye noshukela wegazi), kwehle kakhulu eqenjini le-Lingzhi ngenkathi iqembu le-placebo lihlala endaweni (Umfanekiso 3).