Wu Tingyao

Ma ejiri ya naanị ya ma ọ bụ jikọtara ya, Lingzhi (nke a na-akpọ Ganoderma lucidum ma ọ bụ Reishi) nwere mmetụta nke ịchịkwa ọbara mgbali, na-ebelata mgbaàmà nke onwe ya na imeziwanye lipids ọbara.Ọzọkwa, iji Lingzhi ogologo oge agaghị akpata mmetụta ọjọọ na ọrụ ahụ.Maka nkọwa, lee "Nnwale ụlọ ọgwụ afọ 50 gara aga ekwenyela na Lingzhi nwere ike imeziwanye ọbara mgbali elu" yana "Nchọpụta ụlọ ọgwụ kwadoro na Lingzhi na-eme ka ọbara mgbali elu dịkwuo elu ma ọ dịghị emetụta ọbara mgbali elu".

Agbanyeghị, ọ bụghị naanị na Lingzhi nwere uru ndị a dị n'elu maka ọbara mgbali elu kamakwa ọ na-eme ka viscosity ọbara dịkwuo mma, microcirculation (ekesa ọbara nke capillaries), shuga ọbara na nguzogide insulin na ndị ọrịa nwere ọbara mgbali elu.Ọbụlagodi na-enweghị emetụta ọbara mgbali elu, ọ nwere ike ịkwalite microcirculation ma mee ka ọbara gbasaa na ndị nwere ahụike.

Lingzhi na-eme ka ọbara mgbali elu na ndị ọrịa nwere ọbara mgbali elu nwere viscosity dị elu.

Na 1992, Shanghai Medical University na Wakan Shoyaku Laboratory Co jikọtara ọnụ bipụtara akụkọ gbasara ahụike na "Journal of Chinese Pharmaceutical Sciences", nke nyochara uru nke iri Lingzhi na ndị ọrịa nwere ma ọrịa obi na ọbara viscosity dị elu.A nwalere ngụkọta nke isiokwu 33 (afọ 45 ruo 86), na 17 n'ime ha nwere ọbara mgbali elu.

Ha were mbadamba 2 Lingzhi (nwere 110 mg nke mmiri mmiri na-amị mkpụrụ nke Lingzhi, nke ya na 2.75 g Lingzhi na-amị mkpụrụ) kwa ụbọchị.Mgbe izu 2 gachara, ihe karịrị ọkara nke isiokwu ahụ mere ka mgbaàmà ha dịkwuo mma dị ka isi ọwụwa, mgbakasị ahụ, nhụjuanya nke akụkụ ahụ, nkwụsị obi na ehighị ụra nke ọma;maka ndị nwere ọbara mgbali elu, systolic na diastolic ọbara mgbali gbadara site na 12.5 mmHg (8.5%) na 6.4 mmHg (7.2%), n'otu n'otu, nke bụ nnukwu ọdịiche dị ịrịba ama ma e jiri ya tụnyere tupu ule ahụ (Njirimara 1).

Enwere ike imetụta ọbara mgbali elu site na ọnụọgụ obi (ọnụọgụ oge obi na-akụ kwa nkeji na izu ike) ma na-ejikọta ya na viscosity ọbara (nguzogide ọbara).

Ebe ọ bụ na isiokwu niile (gụnyere ndị nwere ọbara mgbali elu) enweghị ọdịiche dị ịrịba ama na ọnụọgụ obi tupu ule ahụ na mgbe ule ahụ gasịrị (74 ugboro → 77 ugboro), ha niile nọ n'ọnọdụ nkịtị, ma viscosity ọbara na-ebelata nke ukwuu.Ya mere, a na-eche na ihe mere Lingzhi nwere ike isi wedata ọbara mgbali elu nwere ike jikọta ya na mmụba nke viscosity ọbara.

Lingzhi na-eme ka ọbara mgbali elu siri ike na-agwọ ọrịa ma na-emekwa ka viscosity ọbara na microcirculation dịkwuo mma.

Iji kwadokwuo na enwere mmekọrịta dị n'etiti mmụba nke ọbara mgbali elu nke Lingzhi na mma nke viscosity ọbara, ndị otu sitere na Shanghai Medical University na Wakan Shoyaku Laboratory Co, na mmekorita ya na Ụlọ Ọgwụ Ndị Mmadụ anọ nke Xuzhou City, jiri otu ihe ahụ mee ihe. Nkwadebe Lingzhi dị ka ọ dị n'ọmụmụ ihe a dị n'elu iji duzie usoro (nke a jikọtara ọnụ), kpuru ìsì abụọ (ma ndị nyocha na isiokwu ndị ahụ amataghị otu ndị e kenyere isiokwu ahụ) yana nyocha ụlọ ọgwụ na-achịkwa placebo na ndị ọrịa nwere ọbara mgbali elu.

Dị ka akwụkwọ nyocha nke e bipụtara na "Journal of Chinese Microcirculation" na 1999, "ndị ọrịa na-agba ume ọbara mgbali elu" bụ ndị sonyere na nyocha ụlọ ọgwụ gụnyere ndị ọrịa nwere ọbara mgbali elu dị mkpa bụ ndị natara ọgwụgwọ nke captopril (angiotensin converting enzyme inhibitor) ma ọ bụ nimodipine (calcium antagonist). ) ihe karịrị otu ọnwa mana ọbara mgbali ha ka na-akarị 140/90 mmHg.

Nkezi afọ nke isiokwu ndị a bụ 57.8 ± 9.6 afọ, na oke nwoke na nwanyị bụ ihe dịka 2: 1.N'oge ule ahụ, ndị ọrịa na-ewere ọgwụ ndị ọdịda anyanwụ na-ewere ọgwụ ndị ọdịda anyanwụ dịka ha na-emebu.Otu placebo (ikpe iri na atọ) na-ewere placebo kwa ụbọchị ebe otu Lingzhi (ikpe 27) na-ewere mbadamba 6 Lingzhi kwa ụbọchị (nwere 330 mg nke mmiri mkpụrụ osisi Lingzhi), nke ya na 8.25 g nke anụ ahụ Lingzhi;dose a ji okpukpu atọ karịa nke ule ụlọ ọgwụ ahụ e kwuru n'elu nke e bipụtara na 1992).

(1) Ọganihu zuru oke na mgbali ọbara
Mgbe ọnwa 3 gachara ule, ọbara mgbali elu nke otu Lingzhi, ma ọ bụ ọbara mgbali elu aortic (na-atụ ogwe aka), ọbara mgbali elu arteriolar (na-atụ mkpịsị aka) ma ọ bụ ọbara mgbali elu (na-atụ ntu ntu-akpụkpọ anụ ahụ dị n'akụkụ ala ala). ọnụ nke ntu na ikpuchi mgbọrọgwụ nke ntu) dị ntakịrị ala karịa tupu ule ahụ, ma ọ dịghị mgbanwe dị ịrịba ama na placebo otu (Figure 2).

(2) viscosity ọbara belatakwara
N'otu oge ahụ, ihe ndị bụ isi na-egosi maka nyochaa viscosity ọbara, gụnyere nnukwu shear (ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ ọsọ) ọbara ọbara dum, obere shear (obere ọsọ ọsọ ọsọ ọsọ) ọbara viscosity na plasma viscosity nke na-emetụta ọbara viscosity dum (ọbara). viscosity mgbe ewepụrụ mkpụrụ ndụ ọbara, nke ọdịnaya nke protein, abụba na shuga na-emetụta), belatara nke ukwuu na otu Lingzhi ebe otu placebo nọ n'ọnọdụ (Nyocha 3).